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Guest Editor ’s bio: Dr. Zuzana Diamant
Zuzana Diamant, MD PhD, is a pulmonologist and clinical pharmacologist, guest professor at the Dept of Microbiology Immunology& Transplantation, Ku Leuven, Catholic University of Leuven, Belgium and senior researcher and past guest-professor of Asthma and Allergy Research at Sk åne University Hospital in Lund, Sweden. She is also affiliated with the Department of Clinical Pharmacy and Pharmacology at the University Medical Center of Groningen, Netherlands and Department of Respiratory Medicine at Thomayer Hospital, Charles University, Prague, Czech Republic.
Source: Respiratory Medicine - September 1, 2023 Category: Respiratory Medicine Authors: Zuzanna Diamant Source Type: research
Breakthroughs in understanding and treating eosinophilic gastrointestinal diseases presented at the CEGIR/TIGERs Symposium at the 2022 American Academy of Allergy, Asthma & Immunology Meeting
The Consortium of Eosinophilic Gastrointestinal Diseases (CEGIR) and The International Gastrointestinal Eosinophil Researchers (TIGERs) organized a day-long symposium at the 2022 Annual Meeting of the American Academy of Allergy, Asthma& Immunology. The symposium featured a review of recent discoveries in the basic biology and pathogenesis of eosinophilic gastrointestinal diseases (EGIDs) in addition to advances in our understanding of the clinical features of EGIDs. Diagnostic and management approaches were reviewed and debated, and clinical trials of emerging therapies were highlighted.
Source: Journal of Allergy and Clinical Immunology - September 1, 2023 Category: Allergy & Immunology Authors: Mirna Chehade, Benjamin L. Wright, Dan Atkins, Seema S. Aceves, Steven J. Ackerman, Amal H. Assa ’ad, Maureen Bauer, Margaret H. Collins, Scott P. Commins, Carla M. Davis, Evan S. Dellon, Bethan Doerfler, Gerald J. Gleich, Sandeep K. Gupta, David A. Hil Source Type: research
Changing with the times —learning to pivot as an academic allergist
In 535 BCE, Heraclitus said “Change is the only constant in life.” As changes continue in allergy and immunology (AI) with respect to practice types, models and patient complexity, it is critical that trainees are provided the skills needed to navigate this ever-changing environment. The article by Dr Zafra and Dr Chiu ill ustrates the changes in recruitment, cost of medical education, salaries, and ACGME standards and wellness.1 We like to take this a step further focusing on the many domains of wellness: emotional, spiritual, intellectual, social, physical, environmental, financial, and occupational.
Source: Annals of Allergy, Asthma and Immunology - September 1, 2023 Category: Allergy & Immunology Authors: Theresa A. Bingemann, Vivian Hernandez-Trujillo Tags: Editorial Source Type: research
Chronic sinusitis in 2023
Estimates suggest that chronic rhinosinusitis (CRS) may affect up to 1 in 8 persons.1 CRS is a challenging condition that can have a dramatic effect on quality of life. If we remember that there are only 5 basic human senses and appreciate that olfactory dysfunction is a cardinal feature of CRS, we can begin to grasp the impact of living with this disease. By definition, CRS lasts at least 3 months, and estimates suggest that impairment of smell occurs in approximately 60% to 80% of patients.2,3 Compounding the impact on smell, nearly 28% of patients also experience dysgeusia.
Source: Annals of Allergy, Asthma and Immunology - September 1, 2023 Category: Allergy & Immunology Authors: Marcus S. Shaker Tags: Editorial Source Type: research
Resources, resources everywhere. However, not for everyone
In a survey conducted by the Pew Research Center, a significant majority (specifically 72%) of internet users reported searching online for medical information.1 Naturally, the question arises: Are publicly available health care –related educational resources sufficiently accessible? The American Medical Association recommends that health-related public information should be presented at or lesser than a sixth-grade reading level. As per a United States Department of Education report from 1993, most of the health care lit erature is written at a tenth-grade or higher reading level.
Source: Annals of Allergy, Asthma and Immunology - September 1, 2023 Category: Allergy & Immunology Authors: Viren Kaul, Nayab Ahmed Tags: Editorial Source Type: research
Causes and implications of increasing costs of prescription medications for allergists
Affecting 10% to 50% of the population, allergic rhinitis (AR) is 1 of the world's most prevalent chronic illnesses, generating a significant burden to society through treatment costs and quality-of-life decrements.1 In the United States, the annual cost of AR is estimated to range from $2 to $5 billion (2003 estimate).1 Allergen immunotherapy is an option for treating AR, but pharmaceutical medications remain the cornerstone of management. Unfortunately, as detailed in the thought-provoking article by Mi et al,2 the cost of many of these rhinologic medications has been increasing, adding more financial burden to patients with AR.
Source: Annals of Allergy, Asthma and Immunology - September 1, 2023 Category: Allergy & Immunology Authors: Di Sun, Christopher D. Codispoti Tags: Editorial Source Type: research
Comprehensive care of adults with respiratory diseases must include vaccines
Vaccines are among the most effective tools we have to improve and save lives, but only if they are administered to eligible patients. In this issue, Naeger et al1 highlight the major opportunities that the health care community has to achieve high adult vaccination rates. These vaccines include those for prevention of coronavirus disease 2019 (COVID-19), pneumococcal, and influenza, diseases that respiratory health professionals are most aware of, plus pertussis (in Tdap), herpes zoster (HZ, shingles), and as of May 3, 2023, respiratory syncytial viral, for which adults with asthma and chronic obstructive pulmonary diseas...
Source: Annals of Allergy, Asthma and Immunology - September 1, 2023 Category: Allergy & Immunology Authors: Barbara P. Yawn, Dennis Williams, Gregory Poland Tags: Editorial Source Type: research
Pharmacokinetics between intramuscular and subcutaneous manual epinephrine administration
We read with interest the article titled, “Comparison of the pharmacokinetics between intramuscular and subcutaneous manual epinephrine administration” by Tanimoto et al.1 There are some limitations worth noting.
Source: Annals of Allergy, Asthma and Immunology - September 1, 2023 Category: Allergy & Immunology Authors: T. Ted Song, Luke M. Pittman Tags: Correspondence Source Type: research
Marginal Zone
Cartootorial: Pollen counts are a popular topic for television news programs.1 Meteorologists typically obtain this information from local allergists; however, outside of major cities, the accuracy of pollen forecasts becomes questionable due to the limited number of certified pollen counting stations.1,2 This is, in part, because pollen counting is labor intensive and requires specialized training.2,3 To obtain pollen counts, pollen is collected from a validated air collection device and stained a fuchsia color (Calberla's solution) that adheres to the exine, or rigid outer wall of the pollen.
Source: Annals of Allergy, Asthma and Immunology - September 1, 2023 Category: Allergy & Immunology Authors: Erin L. Reigh Tags: Marginal Zone Source Type: research
80 years of skin testing evaluation in annals
When reading the article entitled “Evaluation of skin testing in allergy: a discussion of causative factors in misleading reactions,” one cannot help but acknowledge that Lieutenant Commander Steele's review written 80 years ago is a lesson in humility.1 Well before the discovery of immunoglobulin E or the mast cell, Dr Steele a cknowledges skin testing's utility no differently than we would today. He writes that it is only a valuable adjunct to the clinical findings while rejecting the skeptic's view that it is “a semi-cabalistic rite bordering on charlatanism” or the overzealous advocate's overinterpretation of minor variations.
Source: Annals of Allergy, Asthma and Immunology - September 1, 2023 Category: Allergy & Immunology Authors: John J. Oppenheimer, Harold Nelson Tags: Editorial Source Type: research
Air Pollution and Diet: Potential Interacting Exposures in Asthma
AbstractPurpose of ReviewTo provide a review of emerging literature describing the impact of diet on the respiratory response to air pollution in asthma.Recent FindingsAsthma phenotyping (observable characteristics) and endotyping (mechanistic pathways) have increased the specificity of diagnostic and treatment pathways and opened the doors to the identification of subphenotypes with enhanced susceptibility to exposures and interventions. Mechanisms underlying the airway immune response to air pollution are still being defined but include oxidative stress, inflammation, and activation of adaptive and innate immune response...
Source: Current Allergy and Asthma Reports - September 1, 2023 Category: Allergy & Immunology Source Type: research
Establishing a Virtual Home Assessment Program: from Concept to Implementation as a Result of the COVID-19 Pandemic
This article describes the development and delivery process, timelines of caregiver interaction, and guidelines for performing virtual home assessments. It summarizes the challenges and benefits of using a virtual process for delivering home assessment services for asthma and allergy patients. Overall, caregivers indicated they found the use of virtual technology had significant benefits for them including their personal comfort and the time efficiency gained by using virtual visits to interact with Healthy Homes Program staff.
Source: Current Allergy and Asthma Reports - September 1, 2023 Category: Allergy & Immunology Source Type: research
Computer-Assisted Clinical Diagnosis and Treatment
AbstractPurpose of ReviewComputer-assisted diagnosis and treatment (CAD/CAT) is a rapidly growing field of medicine that uses computer technology and telehealth to aid in the diagnosis and treatment of various diseases. The purpose of this paper is to provide a review on computer-assisted diagnosis and treatment. This technology gives providers access to diagnostic tools and treatment options so that they can make more informed decisions leading to improved patient outcomes.Recent FindingsCAD/CAT has expanded in allergy and immunology in the form of digital tools that enable remote patient monitoring such as digital inhale...
Source: Current Allergy and Asthma Reports - September 1, 2023 Category: Allergy & Immunology Source Type: research
Multiple Sclerosis Pathogenesis and Updates in Targeted Therapeutic Approaches
AbstractPurpose of ReviewIn this review, we provide a comprehensive update on current scientific advances and emerging therapeutic approaches in the field of multiple sclerosis.Recent FindingsMultiple sclerosis (MS) is a common disorder characterized by inflammation and degeneration within the central nervous system (CNS). MS is the leading cause of non-traumatic disability in the young adult population. Through ongoing research, an improved understanding of the disease underlying mechanisms and contributing factors has been achieved. As a result, therapeutic advancements and interventions have been developed specifically ...
Source: Current Allergy and Asthma Reports - September 1, 2023 Category: Allergy & Immunology Source Type: research
Role of Small Molecule Ligands in IgE-Mediated Allergy
AbstractPurpose of ReviewA significant fraction of allergens bind small molecular ligands, and many of these compounds are classified as lipids. However, in most cases, we do not know the role that is played by the ligands in the allergic sensitization or allergic effector phases.Recent FindingsMore effort is dedicated toward identification of allergens ’ ligands. This resulted in identification of some lipidic compounds that can play active immunomodulatory roles or impact allergens’ molecular and allergic properties.SummaryFour allergen families (lipocalins, NPC2, nsLTP, and PR-10) are among the best characterized in...
Source: Current Allergy and Asthma Reports - September 1, 2023 Category: Allergy & Immunology Source Type: research
