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Condition: Asthma

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Effects of Allergen Exposure and Environmental Risk Factors in Schools on Childhood Asthma
AbstractPurpose of ReviewThis review aims to assess the prevalence of common allergen exposures and environmental risk factors for asthma in schools, examine the underlying mechanisms of these environmental risk factors, and explore possible prevention strategies.Recent FindingsCockroach, mouse, dust mites, fungi, viral infections, ozone pollution, and cleaning products are common allergen exposures and environmental risk factors in schools which may affect asthma morbidity. Novel modifiable environmental risk factors in schools are also being investigated to identify potential associations with increased asthma morbidity....
Source: Current Allergy and Asthma Reports - August 31, 2023 Category: Allergy & Immunology Source Type: research

From the Pages of AllergyWatch
For this edition of From the Pages of AllergyWatch I've chosen articles from AllergyWatch focusing on atopic dermatitis, the main theme of this month's Annals. The first article, with comments from Dr. Spriet, investigates various biomarkers in stratum corneum tape strips to predict development of atopic dermatitis in infants and young children. The next article, with comments from Dr. Otani, evaluates the need for closer monitoring of the use of corticosteroids in patients with atopic dermatitis.
Source: Annals of Allergy, Asthma and Immunology - August 31, 2023 Category: Allergy & Immunology Authors: Stanley M. Fineman, Sarah Spriet, Iris Otani, Gerald B. Lee Tags: Special Series Source Type: research

How Patients With Asthma Can Reap the Benefits of Exercise How Patients With Asthma Can Reap the Benefits of Exercise
More and more research shows physical activity can boost lung function and ease the symptoms of asthma. But it can also trigger an asthma attack. Here ’s the best approach.WebMD Health News
Source: Medscape Allergy Headlines - August 30, 2023 Category: Allergy & Immunology Tags: Pulmonary Medicine News Source Type: news

Academic Interest of Allergists in Atopic Dermatitis before and after Approval of Systemic Immunomodulators
Ann Allergy Asthma Immunol. 2023 Aug 28:S1081-1206(23)00635-X. doi: 10.1016/j.anai.2023.08.593. Online ahead of print.NO ABSTRACTPMID:37648108 | DOI:10.1016/j.anai.2023.08.593
Source: Annals of Allergy, Asthma and Immunology - August 30, 2023 Category: Allergy & Immunology Authors: Sarah Zhang Peck Y Ong Source Type: research

Omalizumab Treatment in Uncontrolled Asthma and CRSwNP Patients, with Previous Endoscopic Sinus Surgery, to Improve Quality of Life and Endoscopic Outcomes: a Two-Year Real-Life Study
The objective of this study is to evaluate the effect of omalizumab as an adjunct to endoscopic sinus surgery (ESS) on the treatment of CRSwNP under real-life conditions.Recent FindingsSince the introduction of omalizumab, as the first biologic agent for the treatment of diseases such as severe allergic asthma, different studies have demonstrated an effect of omalizumab on CRSwNP, with significant improvements in sinonasal symptoms and endoscopic scores. The high efficacy derived from mAb therapy and the need for ESS prior to mAb recommended by guidelines, has led to compare both therapeutic alternatives, finding discrepan...
Source: Current Allergy and Asthma Reports - August 30, 2023 Category: Allergy & Immunology Source Type: research

Volume 44, Number 5, 1 September 2023
ALLERGY AND ASTHMA PROCEEDINGS, Volume 44, Number 5, 1 September 2023. Loaded on 2023-08-29
Source: Allergy and Asthma Proceedings - August 30, 2023 Category: Allergy & Immunology Source Type: research

Correlations between IL-36 family cytokines in peripheral blood and subjective and objective assessment results in patients with allergic rhinitis
Interleukin (IL)-36 family cytokines have received increasing attention, especially in the fields of inflammation and immunity research. However, whether IL-36 family cytokine levels are correlated with the re...
Source: Allergy, Asthma and Clinical Immunology - August 30, 2023 Category: Allergy & Immunology Authors: Jia Gu, Gang Qin, Liang Jiang, Wei Xu, Yuanyuan Wang, Jiangxue Liao, Hongzhu Pan and Zhuoping Liang Tags: Research Source Type: research

Neighborhood Factors in Childhood May Influence Asthma Risk
(MedPage Today) -- Living in neighborhoods with high or very high opportunity in early life was associated with lower childhood asthma incidence compared with living in neighborhoods with low opportunity, according to a nationwide cohort study...
Source: MedPage Today Allergy - August 29, 2023 Category: Allergy & Immunology Source Type: news

Perception of burden of oral and inhaled corticosteroid adverse effects on asthma-specific quality of life
CONCLUSION: The most burdensome AEs may not be the AEs that would cause patients to stop therapy. Furthermore, qualitative focus groups suggest a psychosocial burden associated with ICS, which needs further investigation.PMID:37643678 | DOI:10.1016/j.anai.2023.08.595
Source: Annals of Allergy, Asthma and Immunology - August 29, 2023 Category: Allergy & Immunology Authors: Purnadeo N Persaud Annie P Tran Donna Messner J Daryl Thornton Dennis Williams Logan J Harper Vickram Tejwani Source Type: research

Autoinflammatory gene mutations associated with eosinophilia and asthma
We describe five patients with uncontrolled respiratory symptoms that were seen at St. Joesph ’s Healthcare i...
Source: Allergy, Asthma and Clinical Immunology - August 29, 2023 Category: Allergy & Immunology Authors: Bashayr M. Alotaibi, Raquel Lopez Rodriguez, Carmen Venegas Garrido, Lucia Gonzalez Bravo, Nader Khalidi and Parameswaran Nair Tags: Case report Source Type: research

Cyclosporine for omalizumab-refractory chronic urticaria: a report of five cases
While both the AAAAI/ACAAI and the EAACI/GA2LEN/EuroGuiDerm/APAAACI guidelines recommend starting cyclosporine for patients with chronic urticaria who have had an inadequate response to omalizumab, many clinician...
Source: Allergy, Asthma and Clinical Immunology - August 29, 2023 Category: Allergy & Immunology Authors: Anthony F. LaCava and Olajumoke O. Fadugba Tags: Case report Source Type: research

Serum autophagy protein 5 is positively related to T helper 2/T helper 1 ratio, inflammation, and exacerbation in adult asthma patients
This study aimed to evaluate ATG5 levels and its clinical role...
Source: Allergy, Asthma and Clinical Immunology - August 29, 2023 Category: Allergy & Immunology Authors: Changjiang Ke and Sheng Xie Tags: Research Source Type: research

The Promise and Peril of Knowledge Translation For Food Allergy Prevention
Across recent decades, prevention efforts have evolved considerably from dietary avoidance for both mother and infant to a paradigm that actively encourages early infant introduction of potentially allergenic foods.(1) Contemporary management has been informed by controlled trials and meta-analyses of studies supporting early introduction of peanut, egg, and other potentially allergenic foods. Early introduction is promoted as safe and effective around the world.(1)
Source: Annals of Allergy, Asthma and Immunology - August 29, 2023 Category: Allergy & Immunology Authors: Marcus S. Shaker, Elissa M. Abrams, Douglas P. Mack, Edmond S. Chan, Edward G.A. Iglesia, David B.K. Golden, Matthew Greenhawt Tags: Perspective Source Type: research

Allergic rhinitis guidelines knowledge, attitudes, and practices among primary health care physicians: A national multicentre cross-sectional study
CONCLUSION: Our study demonstrates the importance of education and awareness for PHCPs managing AR. ARIA guidelines should be implemented as a standard of care for AR, as PHCPs are the first ones to encounter patients with AR, to improve outcomes and avoid undertreatment and complications.PMID:37636198 | PMC:PMC10451594 | DOI:10.4103/jfmpc.jfmpc_85_23
Source: Primary Care - August 28, 2023 Category: Primary Care Authors: Hisham Almousa Saad M Alsaad Dawood Ismail Saleh Mahjoub Sultan Bin Obaid Saad Alsaleh Source Type: research