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Bioinformatics-based analysis of core genes and pathway enrichment in early diabetic nephropathy
Cell Mol Biol (Noisy-le-grand). 2023 Jul 31;69(7):51-56. doi: 10.14715/cmb/2023.69.7.9.ABSTRACTDiabetic nephropathy (DN) is the main cause of end-stage renal disease (ESRD). Bioinformatics technology was adopted to screen and analyze the core genes of early DN to explore its pathogenesis. GSE30528, GSE96804, and GSE30122 chip data were obtained from Gene Expression Omnibus (GEO) database to screen DN and healthy controls for differentially expressed genes. Gene Ontology (GO), Kyoto Encyclopedia of Genes and Genomes (KEGG) for functional annotation and signaling pathway enrichment; String and Cytoscape were used for protein...
Source: Cellular and Molecular Biology - September 16, 2023 Category: Molecular Biology Authors: Yangwenxuan Han Xiaoyan Liu Jing Shang Na Li Chunjian Zhang Ying Li Jiaxin Zheng Source Type: research
Evaluation of Willis Polygon Morphometry with Cranial Tomographic Angiography
CONCLUSION: We also found that the vessel diameters were similar in the HT, DM and HT+DM groups, and smaller than the control group. In addition, we think that knowing WP morphometric measurements will both guide the radio-anatomical evaluations to be made and increase the level of microanatomical knowledge in surgical treatment.PMID:37715602 | DOI:10.5137/1019-5149.JTN.40346-22.4
Source: Turkish Neurosurgery - September 16, 2023 Category: Neurosurgery Authors: Rukiye Ciftci Aymelek Cetin Hilal Er Ulubaba Deniz Senol Fahri Safa Cinarli Davut Ozbag Source Type: research
Exudative vascular anomalous complex-like lesion of the peripapillary area
CONCLUSION: Exudative intraretinal aneurysmal lesions can occur in areas other than perifoveal area. OCT is an useful investigation for knowing their characteristics and the response to treatment. These aneurysmal lesions irrespective of their location can be called by the name eVAC-like or more aptly retinal capillary macro aneurysms (RCM).PMID:37715627 | DOI:10.1177/11206721231202895
Source: European Journal of Ophthalmology - September 16, 2023 Category: Opthalmology Authors: Shreyas Temkar Kaviyapriya Natarajan Amit Kumar Deb Pradeep Sagar Source Type: research
Comparison of various prediction models in the effect of Roux-en-Y gastric bypass on type 2 diabetes in the Chinese population 5 years after surgery
CONCLUSIONS: T2D was relieved to varying degrees 5 years after RYGB in patients with obesity. The prediction models in ABCD and the Panuzi et al. [34] studies showed the best prediction effects. ABCD was recommended for clinical use because of excellent predictive performance, good statistical test results, and simple and practical design features.PMID:37716844 | DOI:10.1016/j.soard.2023.05.012
Source: Surgery for Obesity and Related Diseases : official journal of the American Society for Bariatric Surgery - September 16, 2023 Category: Surgery Authors: Chengyuan Yu Zheng Wang Qiqige Wuyun Weijian Chen Zhehong Li Mingyue Shang Nengwei Zhang Source Type: research
Bioinformatics-based analysis of core genes and pathway enrichment in early diabetic nephropathy
Cell Mol Biol (Noisy-le-grand). 2023 Jul 31;69(7):51-56. doi: 10.14715/cmb/2023.69.7.9.ABSTRACTDiabetic nephropathy (DN) is the main cause of end-stage renal disease (ESRD). Bioinformatics technology was adopted to screen and analyze the core genes of early DN to explore its pathogenesis. GSE30528, GSE96804, and GSE30122 chip data were obtained from Gene Expression Omnibus (GEO) database to screen DN and healthy controls for differentially expressed genes. Gene Ontology (GO), Kyoto Encyclopedia of Genes and Genomes (KEGG) for functional annotation and signaling pathway enrichment; String and Cytoscape were used for protein...
Source: Cellular and Molecular Biology - September 16, 2023 Category: Molecular Biology Authors: Yangwenxuan Han Xiaoyan Liu Jing Shang Na Li Chunjian Zhang Ying Li Jiaxin Zheng Source Type: research
Multifunctional and theranostic hydrogels for wound healing acceleration: An emphasis on diabetic-related chronic wounds
Environ Res. 2023 Sep 14:117087. doi: 10.1016/j.envres.2023.117087. Online ahead of print.ABSTRACTHydrogels represent intricate three-dimensional polymeric structures, renowned for their compatibility with living systems and their ability to naturally degrade. These networks stand as promising and viable foundations for a range of biomedical uses. The practical feasibility of employing hydrogels in clinical trials has been well-demonstrated. Among the prevalent biomedical uses of hydrogels, a significant application arises in the context of wound healing. This intricate progression involves distinct phases of inflammation,...
Source: Environmental Research - September 16, 2023 Category: Environmental Health Authors: Pooya M Tehrany Parham Rahmanian Aryan Rezaee Golnaz Ranjbarpazuki Farima Sohrabi Fard Yasaman Asadollah Salmanpour Mohammad Arad Zandieh Ali Ranjbarpazuki Sajedeh Asghari Nazanin Javani Noushin Nabavi Amir Reza Aref Mehrdad Hashemi Mohsen Rashidi Afshin Source Type: research
Emergency department visits associated with wildfire smoke events in California, 2016-2019
We examined associations between smoke events and emergency department visits (EDVs) for respiratory, cardiovascular, diabetes, and mental health outcomes in California during the wildfire season June-December 2016-2019. Daily, zip code tabulation area-level wildfire-specific fine particulate matter (PM2.5) concentrations were aggregated to air basins. A "smoke event" was defined as an air basin-day with a wildfire-specific PM2.5 concentration at or above the 98th percentile across all air basin-days (threshold = 13.5 μg/m3). We conducted a two-stage time-series analysis using quasi-Poisson regression considering lag effe...
Source: Environmental Research - September 16, 2023 Category: Environmental Health Authors: Annie I Chen Keita Ebisu Tarik Benmarhnia Rupa Basu Source Type: research
Evaluation of Willis Polygon Morphometry with Cranial Tomographic Angiography
CONCLUSION: We also found that the vessel diameters were similar in the HT, DM and HT+DM groups, and smaller than the control group. In addition, we think that knowing WP morphometric measurements will both guide the radio-anatomical evaluations to be made and increase the level of microanatomical knowledge in surgical treatment.PMID:37715602 | DOI:10.5137/1019-5149.JTN.40346-22.4
Source: Turkish Neurosurgery - September 16, 2023 Category: Neurosurgery Authors: Rukiye Ciftci Aymelek Cetin Hilal Er Ulubaba Deniz Senol Fahri Safa Cinarli Davut Ozbag Source Type: research
MiRNA a New Insight in Metabolic and Human Diseases: A Review
Cell Mol Biol (Noisy-le-grand). 2023 Aug 31;69(8):102-110. doi: 10.14715/cmb/2023.69.8.16.ABSTRACTThe purpose of this research is to examine existing studies on the association between microRNAs (miRNA) and age-related disorders. The miRNAs are small, noncoding RNA molecules with the ability to regulate gene expression. These are well-established in extracellular circulation, including various types of diseases such as cancer, cardiovascular diseases, and diabetes. Similarly, several miRNAs are associated with certain age-related conditions, such as increased miR-21 expression in cancer patients. Besides that, the miR-122 ...
Source: Atherosclerosis - September 16, 2023 Category: Cardiology Authors: Ibrahim Jafri Source Type: research
Exudative vascular anomalous complex-like lesion of the peripapillary area
CONCLUSION: Exudative intraretinal aneurysmal lesions can occur in areas other than perifoveal area. OCT is an useful investigation for knowing their characteristics and the response to treatment. These aneurysmal lesions irrespective of their location can be called by the name eVAC-like or more aptly retinal capillary macro aneurysms (RCM).PMID:37715627 | DOI:10.1177/11206721231202895
Source: European Journal of Ophthalmology - September 16, 2023 Category: Opthalmology Authors: Shreyas Temkar Kaviyapriya Natarajan Amit Kumar Deb Pradeep Sagar Source Type: research
Bioinformatics-based analysis of core genes and pathway enrichment in early diabetic nephropathy
Cell Mol Biol (Noisy-le-grand). 2023 Jul 31;69(7):51-56. doi: 10.14715/cmb/2023.69.7.9.ABSTRACTDiabetic nephropathy (DN) is the main cause of end-stage renal disease (ESRD). Bioinformatics technology was adopted to screen and analyze the core genes of early DN to explore its pathogenesis. GSE30528, GSE96804, and GSE30122 chip data were obtained from Gene Expression Omnibus (GEO) database to screen DN and healthy controls for differentially expressed genes. Gene Ontology (GO), Kyoto Encyclopedia of Genes and Genomes (KEGG) for functional annotation and signaling pathway enrichment; String and Cytoscape were used for protein...
Source: Cellular and Molecular Biology - September 16, 2023 Category: Molecular Biology Authors: Yangwenxuan Han Xiaoyan Liu Jing Shang Na Li Chunjian Zhang Ying Li Jiaxin Zheng Source Type: research
Multifunctional and theranostic hydrogels for wound healing acceleration: An emphasis on diabetic-related chronic wounds
Environ Res. 2023 Sep 14:117087. doi: 10.1016/j.envres.2023.117087. Online ahead of print.ABSTRACTHydrogels represent intricate three-dimensional polymeric structures, renowned for their compatibility with living systems and their ability to naturally degrade. These networks stand as promising and viable foundations for a range of biomedical uses. The practical feasibility of employing hydrogels in clinical trials has been well-demonstrated. Among the prevalent biomedical uses of hydrogels, a significant application arises in the context of wound healing. This intricate progression involves distinct phases of inflammation,...
Source: Cell Research - September 16, 2023 Category: Cytology Authors: Pooya M Tehrany Parham Rahmanian Aryan Rezaee Golnaz Ranjbarpazuki Farima Sohrabi Fard Yasaman Asadollah Salmanpour Mohammad Arad Zandieh Ali Ranjbarpazuki Sajedeh Asghari Nazanin Javani Noushin Nabavi Amir Reza Aref Mehrdad Hashemi Mohsen Rashidi Afshin Source Type: research
Obstetric care for environmental migrants
ConclusionMaternity healthcare providers are likely to provide care for environmental migrants over the coming years. Environmental disasters and migration as individual factors have complex effects on perinatal health, and environmental migrants may be at risk of specific perinatal complications. Obstetricians and maternity healthcare workers should be aware of these challenges and appreciate the individualised and specialised care that these patients require.
Source: Irish Journal of Medical Science - September 16, 2023 Category: General Medicine Source Type: research
