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Total 118587 results found since Jan 2013.
Missing the Point of Buprenorphine Treatment
A forum reader wrote about concerns over a partner on buprenorphine. Her concerns pointed out a common misperception about the goals of treatment of opioid use disorder using buprenorphine, or using methadone for that matter.
Her question, amended for privacy:
I married the love of my life. He is still he love of my life but has been an addict for 15 of them. Our children have been greatly affected by his addiction. He made promise after promise that he was clean, and I dove back in with complete faith time after time only to get burned.
His addiction started with recreational pills increasing over time, but now he i...
Source: Suboxone Talk Zone - June 17, 2017 Category: Addiction Authors: Jeffrey Junig MD PhD Tags: Addiction Buprenorphine Suboxone treatment buprenorphine treatment opioid taper rapid detox Suboxone taper Source Type: blogs
The SEARCH for Diabetes in Youth Study: Rationale, Findings, and Future Directions.
Abstract
The SEARCH for Diabetes in Youth (SEARCH) study was initiated in 2000, with funding from the Centers for Disease Control and Prevention and support from the National Institute of Diabetes and Digestive and Kidney Diseases, to address major knowledge gaps in the understanding of childhood diabetes. SEARCH is being conducted at five sites across the U.S. and represents the largest, most diverse study of diabetes among U.S. youth. An active registry of youth diagnosed with diabetes at age <20 years allows the assessment of prevalence (in 2001 and 2009), annual incidence (since 2002), and trends by age, ra...
Source: Diabetes Care - November 25, 2014 Category: Endocrinology Authors: Hamman RF, Bell RA, Dabelea D, D'Agostino RB, Dolan L, Imperatore G, Lawrence JM, Linder B, Marcovina SM, Mayer-Davis EJ, Pihoker C, Rodriguez BL, Saydah S, for the SEARCH for Diabetes in Youth Study Group Tags: Diabetes Care Source Type: research
Prevalence, Characteristics and Clinical Diagnosis of Maturity Onset Diabetes of the Young Due to Mutations in HNF1A, HNF4A, and Glucokinase: Results from the SEARCH for Diabetes in Youth.
Conclusions/Interpretation:In this systematic study of MODY in a large pediatric US diabetes cohort, unselected by referral pattern or family history, MODY was usually misdiagnosed and incorrectly treated with insulin. While many type 2 diabetes-like metabolic features were less common in the mutation-positive group, no single characteristic identified all patients with mutations. Clinicians should be alert to the possibility of MODY diagnosis, particularly in antibody negative youth with diabetes.
PMID: 23771925 [PubMed - as supplied by publisher]
Source: The Journal of Clinical Endocrinology and Metabolism - June 14, 2013 Category: Endocrinology Authors: Gilliam LK, Pihoker C, Ellard S, Hattersley AT, Dabelea D, Davis C, Dolan LM, Greenbaum CJ, Imperatore G, Lawrence JM, Marcovina SM, Mayer-Davis E, Rodriguez BL, Steck AK, Williams DE, for the SEARCH for Diabetes in Youth Study Group Tags: J Clin Endocrinol Metab Source Type: research
Prevalence of Diabetes Mellitus in U.S. Youth in 2009: The SEARCH for Diabetes in Youth Study.
ConclusionDiabetes mellitus, one of the leading chronic diseases in childhood, affects over 190,000 (1 out of 433) youth less than age 20 years in the US, with racial and ethnic disparities seen in diabetes prevalence, overall and by diabetes type.
PMID: 24041677 [PubMed - as supplied by publisher]
Source: Diabetes Care - September 16, 2013 Category: Endocrinology Authors: Pettitt DJ, Talton J, Dabelea D, Divers J, Imperatore G, Lawrence JM, Liese AD, Linder B, Mayer-Davis EJ, Pihoker C, Saydah SH, Standiford DA, Hamman RF, for the SEARCH for Diabetes in Youth Study Group Tags: Diabetes Care Source Type: research
Peripheral Neuropathy in Adolescents and Young Adults With Type 1 and Type 2 Diabetes From the SEARCH for Diabetes in Youth Follow-Up Cohort: A pilot study.
CONCLUSIONSDPN prevalence among youth with type 2 diabetes approached rates reported in adult populations with diabetes. Our findings suggest not only that youth with diabetes are at risk for DPN but also that many already show measurable signs of DPN.
PMID: 24144652 [PubMed - as supplied by publisher]
Source: Diabetes Care - October 21, 2013 Category: Endocrinology Authors: Jaiswal M, Lauer A, Martin CL, Bell RA, Divers J, Dabelea D, Pettitt DJ, Saydah S, Pihoker C, Standiford DA, Rodriguez BL, Pop-Busui R, Feldman EL, for The SEARCH For Diabetes In Youth Study Group Tags: Diabetes Care Source Type: research
Factors influencing time to case registration for youth with type 1 and type 2 diabetes: SEARCH for Diabetes in Youth Study.
CONCLUSIONS: These findings highlight the need for continued childhood diabetes surveillance to identify future trends and influences on changes in prevalence and incidence.
PMID: 27664849 [PubMed - as supplied by publisher]
Source: Annals of Epidemiology - August 31, 2016 Category: Epidemiology Authors: Crume TL, Hamman RF, Isom S, Talton J, Divers J, Mayer-Davis EJ, Zhong VW, Liese AD, Saydah S, Standiford DA, Lawrence JM, Pihoker C, Dabelea D, SEARCH for Diabetes in Youth Study Group Tags: Ann Epidemiol Source Type: research
Buprenorphine: A Key Ingredient in the Fight to Solve America's Pain Crisis
"If you do not change direction, you may end up where you are heading." -- Lao Tzu Over the last few weeks, the CDC, the U.S. Department of Health and Human Services (HHS), and the president of the United States have all separately hit the emergency button over the subject of chronic pain treatment and opioid pain killers. Concerns over the rising tide of pain killer addiction, accidental overdose deaths, and a carryover effect causing a steep rise in heroin use have made this a "code blue" emergency for Washington. President Obama has made it clear that addressing the opioid epidemic is now an administration priority, and...
Source: Healthy Living - The Huffington Post - April 5, 2016 Category: Consumer Health News Source Type: news
Transdermal Buprenorphine Relieves Neuropathic Pain: A Randomized, Double-Blind, Parallel-Group, Placebo-Controlled Trial in Diabetic Peripheral Neuropathic Pain
CONCLUSIONS
Transdermal buprenorphine, when tolerated, is an effective therapy for DPNP and provides another option to manage this challenging painful condition. Nausea and constipation need to be managed proactively to optimize treatment outcomes.
Source: Diabetes Care - August 22, 2016 Category: Endocrinology Authors: Simpson, R. W.; Wlodarczyk, J. H. Tags: Clinical Care/Education/Nutrition/Psychosocial Research Source Type: research
Obama and the TREAT Act
I just read an article in the Daily Beast that reads like a better version of something I would write about the value of medication-assisted treatment of opioid dependence. I appreciate Christopher Moraff telling a story that has been untold far too long, and I hope the story raises questions across the country.
But I have something else on my mind that deserves a story of its own. I am just a small-town psychiatrist in the Midwest, of course, and so I could be missing something. I watch Veep and House of Cards, but I assume that the political games in those shows are grossly exaggerated. I’ll offer a bit of ...
Source: Suboxone Talk Zone - May 12, 2016 Category: Addiction Authors: Jeffrey Junig MD PhD Tags: Addiction Buprenorphine Legal Public policy Suboxone treatment heroin addiction Obama patient cap TREAT Act Source Type: blogs
Obama’s Lousy Suboxone Offer
I was reading more about Obama’s executive order over at Dr. Burson’s blog. I guess she is a ‘competitor’ in the blogging world, but I have to admit that her blog has a lot more detail about the issue than I do. If you haven’t been there yet, check it out. Keep coming back here too of course!
She wrote recently about the rules that would be required by the Feds, in order for them t o allow us the ‘right’ to treat people with buprenorphine. I wrote to Dr. Burson after reading her post that she is providing the facts, and I can’t help but provide the emotion. And af...
Source: Suboxone Talk Zone - May 15, 2016 Category: Addiction Authors: Jeffrey Junig MD PhD Tags: Addiction Buprenorphine Public policy Suboxone treatment heroin addiction obama suboxone treatment Suboxone treatment cap TREAT Act Source Type: blogs
Obama ’s Lousy Suboxone Offer
I was reading more about Obama’s executive order over at Dr. Burson’s blog. I guess she is a ‘competitor’ in the blogging world, but I have to admit that her blog has a lot more detail about the issue than I do. If you haven’t been there yet, check it out. Keep coming back here too of course!
She wrote recently about the rules that would be required by the Feds, in order for them t o allow us the ‘right’ to treat people with buprenorphine. I wrote to Dr. Burson after reading her post that she is providing the facts, and I can’t help but provide the emotion. And af...
Source: Suboxone Talk Zone - May 15, 2016 Category: Addiction Authors: Jeffrey Junig MD PhD Tags: Addiction Buprenorphine Public policy Suboxone treatment heroin addiction obama suboxone treatment Suboxone treatment cap TREAT Act Source Type: blogs
Opioid use disorder and type 2 diabetes mellitus: Effect of participation in buprenorphine-naloxone substitution programs on glycemic control.
CONCLUSION: Patients with diabetes who also suffer from opioid use disorder achieve significant (P = .011) improvement in glycemic control when treated with buprenorphine-naloxone substitution therapy compared with other patients with diabetes. Treating opioid use disorder with buprenorphine-naloxone substitution therapy has an unintended positive effect on diabetes management.
PMID: 28701461 [PubMed - in process]
Source: Canadian Family Physician Medecin de Famille Canadien - July 1, 2017 Category: Primary Care Authors: Tilbrook D, Jacob J, Parsons P, Edwards C, Loewen K, Kelly L Tags: Can Fam Physician Source Type: research
Tapentadol, Buprenorphine, and Levorphanol for the Treatment of Neuropathic Pain: a Systematic Review
The objective of this systematic review is to present the available evidence for the utilization of the atypical opioids tapentadol, buprenorphine, and levorphanol for the treatment of neuropathic pain.Recent FindingsIn total, 1619 articles were retrieved of which 10 studies were included. Of 5 included studies pertaining to tapentadol, 4 studies show tapentadol monotherapy to be effective for the treatment of diabetic peripheral neuropathy or chronic, radiating low back pain. Of the 3 studies included for buprenorphine, only one was a randomized controlled trial found not to have a statistically significant reduction in p...
Source: Current Pain and Headache Reports - February 25, 2021 Category: Neurology Source Type: research
