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Vaccination: Pneomococcal Vaccine

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Total 3009 results found since Jan 2013.

Efficacy of whole-cell pneumococcal vaccine in mice: A systematic review and meta-analysis
ConclusionsThe best protocol for use of a WCV is its application with CT adjuvant administered intranasally in three inoculations at doses of 10⁸ CFU. Further studies performed under similar conditions to obtain accurate results on the effectiveness of this vaccine are recommended.
Source: Microbial Pathogenesis - July 5, 2018 Category: Infectious Diseases Source Type: research

Th17 responses to pneumococcus in blood and adenoidal cells in children.
This article is protected by copyright. All rights reserved. PMID: 30325010 [PubMed - as supplied by publisher]
Source: Clinical and Developmental Immunology - October 16, 2018 Category: Allergy & Immunology Authors: Oliver E, Pope C, Clarke E, Langton Hewer C, Ogunniyi AD, Paton JC, Mitchell T, Malley R, Finn A Tags: Clin Exp Immunol Source Type: research

Immunogenicity, safety and tolerability of anti-pneumococcal vaccination in systemic lupus erythematosus patients: An evidence-informed and PRISMA compliant systematic review and meta-analysis
In conclusion, due to the high risk of pneumococcal infection in SLE patients and given the safety and, at least partial, effectiveness according our study in such patients, preventive strategies mainly by immunization are required in all age groups and in those needing immunosuppressive therapy, immunization should be given prior the initiation of the treatment.PROSPERO registration code 103605.
Source: Autoimmunity Reviews - November 6, 2018 Category: Allergy & Immunology Source Type: research

Evidence Based Recommendations for Supportive Care in Multiple Myeloma
Conclusion:Along with anti-myeloma chemotherapy therapy, management of complications (anemia, infections, renal insufficiency) and other associated symptoms is necessary to improve the quality of life.DisclosuresNo relevant conflicts of interest to declare.
Source: Blood - November 21, 2018 Category: Hematology Authors: Qureshi, A., Tariq, M. J., Shah, Z., Abu Zar, M., Aslam, S., Rafae, A., Malik, M. N., Kamal, A., Jose, J. A., Selene, I. I., Shafqat, M., Jamil, F., Durer, S., Durer, C., Anwer, F. Tags: 653. Myeloma: Therapy, excluding Transplantation: Poster I Source Type: research

Interventions to improve vaccine acceptance among rheumatoid arthritis patients: a systematic review
ConclusionsInterventions to enhance vaccine uptake in RA focused almost exclusively on improving provider prescription of vaccines using reminder-type interventions. Although effective in improving vaccination rates, those studies used heterogeneous interventions and behavior change techniques. Few studies measured provider prescribing behavior as an outcome. Future studies targeting providers should measure relevant provided-related outcomes and their impact on patient outcomes, to determine overall efficacy.
Source: Clinical Rheumatology - January 15, 2019 Category: Rheumatology Source Type: research

Current antimicrobial management of community-acquired pneumonia in HIV-infected children.
Authors: Nuttall JJC Abstract INTRODUCTION: Community-acquired pneumonia is a leading cause of morbidity and mortality amongst HIV-infected infants and children. Polymicrobial infection is common and, due to the difficulties in confirming the etiology of pneumonia, empiric broad-spectrum antimicrobial therapy is frequently used. Areas covered: The author based this article on literature identified from PubMed. The author's search terms included: pneumonia, community-acquired pneumonia, HIV, children. The articles reviewed included original studies, recent review articles and current guidelines on the management of ...
Source: Expert Opinion on Pharmacotherapy - January 23, 2019 Category: Drugs & Pharmacology Tags: Expert Opin Pharmacother Source Type: research

The Future of Flu: A Review of the Human Challenge Model and Systems Biology for Advancement of Influenza Vaccinology
Conclusions: Human challenge studies and systems biology approaches are important tools that should be used in concert to advance our understanding of influenza infection and provide targets for novel therapeutics and immunizations. Introduction Although influenza virus was recognized as an important pathogen over a century ago, influenza continues to cause a significant burden of disease. In the United States alone, it's estimated that in the 2017–2018 season there were 959,000 hospitalizations related to influenza illness, and 79,400 deaths (CDC, 2018). Worldwide, WHO estimates that annual influen...
Source: Frontiers in cellular and infection microbiology - April 16, 2019 Category: Microbiology Source Type: research

Pneumococcal vaccination in celiac disease.
Authors: Casella G, Ingravalle F, Abbate G, Monti C, Bonetti F, Bassotti G, Mansueto P, Villanacci V, Carroccio A Abstract INTRODUCTION: Celiac disease (CD) is an immune-mediated disorder associated with gluten exposure in genetically predisposed subjects. Areas covered: Infectious disease is one of the causes of morbidity and mortality in CD patients. Invasive streptococcus pneumoniae (pneumococcus) is a particularly dangerous morbid condition in both the general population and celiac patients. Pneumococcal vaccination is the most effective means for its prevention. Expert opinion: In CD, evaluation of spleen func...
Source: Expert Review of Gastroenterology and Hepatology - April 17, 2019 Category: Gastroenterology Tags: Expert Rev Gastroenterol Hepatol Source Type: research

Cost Effectiveness of Elderly Pneumococcal Vaccination in Presence of Higher-Valent Pneumococcal Conjugate Childhood Vaccination: Systematic Literature Review with Focus on Methods and Assumptions
ConclusionMethodological approaches and assumptions in modeling VE and the indirect effects of childhood vaccination have a major impact on outcomes of decision-analytic models and cost-effectiveness estimates. Considering recently observed trends in the epidemiology of pneumococcal serotypes, there is currently inconclusive evidence regarding the cost effectiveness of pneumococcal vaccination of the elderly due to lack of studies that model key serotypes such as serotype 3 separately from other groups of serotypes.
Source: PharmacoEconomics - April 25, 2019 Category: Health Management Source Type: research

A Critical View of Specific Antibody Deficiencies
Ricardo U. Sorensen1,2,3* 1Professor Emeritus of Pediatrics, Department of Pediatrics, Louisiana State University Health Science Center, New Orleans, LA, United States 2Louisiana Primary Immunodeficiency Network, New Orleans, LA, United States 3Honorary Professor, Faculty of Medicine, University of La Frontera, Temuco, Chile In thisopinion manuscript the author postulates that the present definition of Specific Antibody Deficiency (SAD) needs to be revised and expanded. It is presently defined as a syndrome of low IgG antibody responses to purified Streptococcus pneumoniae capsular polysaccharides vaccine...
Source: Frontiers in Immunology - April 30, 2019 Category: Allergy & Immunology Source Type: research

Serotype distribution of disease-causing Streptococcus pneumoniae in Thailand: A systematic review.
CONCLUSION: This review demonstrates that the serotypes which were most responsible for disease in Thailand are included in PCV10 and PCV13. Better surveillance data of IPD and non-IPD are required for monitoring vaccine effectiveness if PCV is implemented nationally. PMID: 31060951 [PubMed - as supplied by publisher]
Source: Vaccine - May 2, 2019 Category: Allergy & Immunology Authors: Hocknell RE, Cleary DW, Srifeungfung S, Clarke SC Tags: Vaccine Source Type: research

Pneumococcal conjugate vaccines for preventing acute otitis media in children.
CONCLUSIONS: Administration of the licenced CRM197-PCV7 and PHiD-CV10 during early infancy is associated with large relative risk reductions in pneumococcal AOM. However, the effects of these vaccines on all-cause AOM is far more uncertain. We found no evidence of a beneficial effect on all-cause AOM of administering PCVs in high-risk infants, after early infancy (i.e. in children one year and above), and in older children with a history of respiratory illness. Compared to control vaccines, PCVs were associated with an increase in mild local reactions (redness, swelling), fever, and pain and/or tenderness. We found no evid...
Source: Cochrane Database of Systematic Reviews - May 27, 2019 Category: General Medicine Authors: Fortanier AC, Venekamp RP, Boonacker CW, Hak E, Schilder AG, Sanders EA, Damoiseaux RA Tags: Cochrane Database Syst Rev Source Type: research

Interventions to Increase the Rate of Influenza and Pneumococcal Vaccination in Patients with Chronic Obstructive Pulmonary Disease: A Scoping Review.
Conclusions: Further, adequately powered, high quality studies are needed. It is crucial for individual institutions to monitor their own vaccination rates to determine if there is scope for performance improvement. PMID: 31208087 [PubMed - in process]
Source: Medicina (Kaunas) - June 14, 2019 Category: Universities & Medical Training Authors: Trethewey SP, Patel N, Turner AM Tags: Medicina (Kaunas) Source Type: research

Pneumococcal Vaccination Strategies Among HIV-infected Adult Patients: A Review of the Literature
Conclusion: Further studies are needed to determine the optimal vaccines and intervals for subsequent revaccinations during the lifetime.
Source: In Vivo - August 29, 2019 Category: Research Authors: GARMPI, A., DAMASKOS, C., GARMPIS, N., PATSOURAS, A., SAVVANIS, S., GRAVVANIS, N., DIAMANTIS, E. Tags: Reviews Source Type: research