Nephrotic Syndrome Complicated with Familial Hypocalciuric Hypercalcemia in an Infant: A Case Report and Comprehensive Literature Review
CONCLUSIONS: This case report is the first documenting familial hypocalciuric hypercalcemia in a child with primary nephrotic syndrome and delineates the familial pedigree. While familial hypocalciuric hypercalcemia is infrequent, our findings affirm its generally benign nature. A critical aspect of patient care involves monitoring for potential complications, including acute pancreatitis or chondrocalcinosis. The indispensability of genetic studies in both diagnosis and the differentiation of related conditions is underscored, emphasizing their pivotal role in enhancing our understanding of this rare yet clinically signif...
Source: Alternative Therapies in Health and Medicine - May 3, 2024 Category: Complementary Medicine Authors: Min Yu Mei Xue Xiaoyan Fan Chunlin Gao Zhengkun Xia Source Type: research
Spectrum of renal disease in scleroderma other than scleroderma renal crisis: A review of the literature
CONCLUSION: The spectrum of kidney involvement in SSc can range from asymptomatic reduction of the glomerular filtration rate to life-threatening scleroderma renal crisis. Therefore, it is essential that physicians closely monitor renal function in these patients for any emerging renal dysfunction.PMID:38699985 | DOI:10.5414/CN111243 (Source: Clinical Nephrology)
Source: Clinical Nephrology - May 3, 2024 Category: Urology & Nephrology Authors: Larabe Farrukh Virginia Steen Lee Shapiro Geovani Faddoul Swati Mehta Source Type: research
Nephrotic Syndrome Complicated with Familial Hypocalciuric Hypercalcemia in an Infant: A Case Report and Comprehensive Literature Review
CONCLUSIONS: This case report is the first documenting familial hypocalciuric hypercalcemia in a child with primary nephrotic syndrome and delineates the familial pedigree. While familial hypocalciuric hypercalcemia is infrequent, our findings affirm its generally benign nature. A critical aspect of patient care involves monitoring for potential complications, including acute pancreatitis or chondrocalcinosis. The indispensability of genetic studies in both diagnosis and the differentiation of related conditions is underscored, emphasizing their pivotal role in enhancing our understanding of this rare yet clinically signif...
Source: Alternative Therapies in Health and Medicine - May 3, 2024 Category: Complementary Medicine Authors: Min Yu Mei Xue Xiaoyan Fan Chunlin Gao Zhengkun Xia Source Type: research
Spectrum of renal disease in scleroderma other than scleroderma renal crisis: A review of the literature
CONCLUSION: The spectrum of kidney involvement in SSc can range from asymptomatic reduction of the glomerular filtration rate to life-threatening scleroderma renal crisis. Therefore, it is essential that physicians closely monitor renal function in these patients for any emerging renal dysfunction.PMID:38699985 | DOI:10.5414/CN111243 (Source: Clinical Nephrology)
Source: Clinical Nephrology - May 3, 2024 Category: Urology & Nephrology Authors: Larabe Farrukh Virginia Steen Lee Shapiro Geovani Faddoul Swati Mehta Source Type: research
Nephrotic Syndrome Complicated with Familial Hypocalciuric Hypercalcemia in an Infant: A Case Report and Comprehensive Literature Review
CONCLUSIONS: This case report is the first documenting familial hypocalciuric hypercalcemia in a child with primary nephrotic syndrome and delineates the familial pedigree. While familial hypocalciuric hypercalcemia is infrequent, our findings affirm its generally benign nature. A critical aspect of patient care involves monitoring for potential complications, including acute pancreatitis or chondrocalcinosis. The indispensability of genetic studies in both diagnosis and the differentiation of related conditions is underscored, emphasizing their pivotal role in enhancing our understanding of this rare yet clinically signif...
Source: Alternative Therapies in Health and Medicine - May 3, 2024 Category: Complementary Medicine Authors: Min Yu Mei Xue Xiaoyan Fan Chunlin Gao Zhengkun Xia Source Type: research
Spectrum of renal disease in scleroderma other than scleroderma renal crisis: A review of the literature
CONCLUSION: The spectrum of kidney involvement in SSc can range from asymptomatic reduction of the glomerular filtration rate to life-threatening scleroderma renal crisis. Therefore, it is essential that physicians closely monitor renal function in these patients for any emerging renal dysfunction.PMID:38699985 | DOI:10.5414/CN111243 (Source: Clinical Nephrology)
Source: Clinical Nephrology - May 3, 2024 Category: Urology & Nephrology Authors: Larabe Farrukh Virginia Steen Lee Shapiro Geovani Faddoul Swati Mehta Source Type: research
Nephrotic Syndrome Complicated with Familial Hypocalciuric Hypercalcemia in an Infant: A Case Report and Comprehensive Literature Review
CONCLUSIONS: This case report is the first documenting familial hypocalciuric hypercalcemia in a child with primary nephrotic syndrome and delineates the familial pedigree. While familial hypocalciuric hypercalcemia is infrequent, our findings affirm its generally benign nature. A critical aspect of patient care involves monitoring for potential complications, including acute pancreatitis or chondrocalcinosis. The indispensability of genetic studies in both diagnosis and the differentiation of related conditions is underscored, emphasizing their pivotal role in enhancing our understanding of this rare yet clinically signif...
Source: Alternative Therapies in Health and Medicine - May 3, 2024 Category: Complementary Medicine Authors: Min Yu Mei Xue Xiaoyan Fan Chunlin Gao Zhengkun Xia Source Type: research
Nephrotic Syndrome Complicated with Familial Hypocalciuric Hypercalcemia in an Infant: A Case Report and Comprehensive Literature Review
CONCLUSIONS: This case report is the first documenting familial hypocalciuric hypercalcemia in a child with primary nephrotic syndrome and delineates the familial pedigree. While familial hypocalciuric hypercalcemia is infrequent, our findings affirm its generally benign nature. A critical aspect of patient care involves monitoring for potential complications, including acute pancreatitis or chondrocalcinosis. The indispensability of genetic studies in both diagnosis and the differentiation of related conditions is underscored, emphasizing their pivotal role in enhancing our understanding of this rare yet clinically signif...
Source: Alternative Therapies in Health and Medicine - May 3, 2024 Category: Complementary Medicine Authors: Min Yu Mei Xue Xiaoyan Fan Chunlin Gao Zhengkun Xia Source Type: research
Nephrotic Syndrome Complicated with Familial Hypocalciuric Hypercalcemia in an Infant: A Case Report and Comprehensive Literature Review
CONCLUSIONS: This case report is the first documenting familial hypocalciuric hypercalcemia in a child with primary nephrotic syndrome and delineates the familial pedigree. While familial hypocalciuric hypercalcemia is infrequent, our findings affirm its generally benign nature. A critical aspect of patient care involves monitoring for potential complications, including acute pancreatitis or chondrocalcinosis. The indispensability of genetic studies in both diagnosis and the differentiation of related conditions is underscored, emphasizing their pivotal role in enhancing our understanding of this rare yet clinically signif...
Source: Alternative Therapies in Health and Medicine - May 3, 2024 Category: Complementary Medicine Authors: Min Yu Mei Xue Xiaoyan Fan Chunlin Gao Zhengkun Xia Source Type: research
Renal histiocytic fibrillary inclusions in a patient with new-onset proteinuria and monoclonal gammopathy
(Source: Virchows Archiv)
Source: Virchows Archiv - May 3, 2024 Category: Pathology Source Type: research
Remission induced by renal protective therapy in nephrotic syndrome with thin basement membrane in an older patient: a case report
ConclusionsThis case illustrated the novel outcomes of combining medical treatment without steroid use for nephrotic syndrome with thin glomerular basement membrane disease. At the time of writing this report, the patient ’s renal function was stable and she was free of edema, although moderate proteinuria and occult hematuria persisted. The final diagnosis was uncertain because of the lack of genetic investigation; however, the response to the aforementioned medical treatment suggests the effectiveness of the supp ortive therapy. (Source: Journal of Medical Case Reports)
Source: Journal of Medical Case Reports - May 3, 2024 Category: General Medicine Source Type: research
Toripalimab Plus Bevacizumab as First-line Treatment for Advanced Hepatocellular Carcinoma: A Prospective, Multicenter, Single-Arm, Phase II Trial
CONCLUSIONS: Toripalimab plus bevacizumab showed a favorable efficacy and safety profile, supporting further studies of this combination regimen as a first-line treatment of advanced HCC.PMID:38687583 | DOI:10.1158/1078-0432.CCR-24-0006 (Source: Clinical Cancer Research)
Source: Clinical Cancer Research - April 30, 2024 Category: Cancer & Oncology Authors: Yajin Chen Cheng-You Du Shunli Shen Wu Zhang Yunfeng Shan Ang Lyu Jianhui Wu Changzhen Shang Xuan Luo Jinxing Wei Heng Xiao Jianguo Qiu Yunpeng Hua Shutong Wang Ting Wang Shengjie Dai Shuhao Zhang Bingying Xie Yinghao Wu Chunyi Hao Source Type: research
Zibotentan Can Be Co-administered with Contraceptives Containing Ethinyl Estradiol and Levonorgestrel: A Pharmacokinetic Drug-Drug Interaction Study
In conclusion, contraception containing ethinyl estradiol/levonorgestrel is regarded possible under zibotentan-containing treatments. This expands choices for women of childbearing potential, supporting diversity in the ZENITH High Proteinuria trial.PMID:38686600 | DOI:10.1002/cpt.3280 (Source: Clinical Pharmacology and Therapeutics)
Source: Clinical Pharmacology and Therapeutics - April 30, 2024 Category: Drugs & Pharmacology Authors: Anne-Kristina Mercier Abigail K Kois Deeyen Karsanji Richard Baldry Filip Birve Maria Hedwall Oleksandr Molodetskyi Michael Gillen Source Type: research
Hydralazine use can be associated with IgM-dominated immune complex-mediated glomerulonephritis
CONCLUSION: The hydralazine-induced autoimmune phenomenon can be seen in IgM-dominant ICMGN, which should be classified as a subtype of membranoproliferative glomerulonephritis.PMID:38685716 | DOI:10.1080/01913123.2024.2346660 (Source: Ultrastructural Pathology)
Source: Ultrastructural Pathology - April 30, 2024 Category: Pathology Authors: Ping L Zhang Brandon D Metcalf Sarang Khan Jamal Abukhaled Khalid Zafar Wei Li Hassan D Kanaan Source Type: research
Toripalimab Plus Bevacizumab as First-line Treatment for Advanced Hepatocellular Carcinoma: A Prospective, Multicenter, Single-Arm, Phase II Trial
CONCLUSIONS: Toripalimab plus bevacizumab showed a favorable efficacy and safety profile, supporting further studies of this combination regimen as a first-line treatment of advanced HCC.PMID:38687583 | DOI:10.1158/1078-0432.CCR-24-0006 (Source: Clinical Cancer Research)
Source: Clinical Cancer Research - April 30, 2024 Category: Cancer & Oncology Authors: Yajin Chen Cheng-You Du Shunli Shen Wu Zhang Yunfeng Shan Ang Lyu Jianhui Wu Changzhen Shang Xuan Luo Jinxing Wei Heng Xiao Jianguo Qiu Yunpeng Hua Shutong Wang Ting Wang Shengjie Dai Shuhao Zhang Bingying Xie Yinghao Wu Chunyi Hao Source Type: research
