The 2012 Briganti nomogram predicts disease progression in surgically treated intermediate-risk prostate cancer patients with favorable tumor grade group eventually associated with some adverse factors
AbstractTo evaluate the prognostic potential of the 2012 Briganti nomogram for pelvic lymph node invasion on disease progression after surgery in intermediate-risk (IR) prostate cancer (PCa) patients with favorable tumor grade (International Society of Urological Pathology grade group 1 or 2), eventually associated with adverse clinical features as PSA between 10 and 20 ng/mL and/or clinical stage T2b. All IR PCa patients treated with robot-assisted radical prostatectomy and eventually extended pelvic lymph node dissection at the Department of Urology of the Integrated University Hospital of Verona between 2013 and 2021,...
Source: Journal of Robotic Surgery - March 23, 2024 Category: Surgery Source Type: research
The superior detection rate of total-body [ < sup > 68 < /sup > Ga]Ga-PSMA-11 PET/CT compared to short axial field-of-view [ < sup > 68 < /sup > Ga]Ga-PSMA-11 PET/CT for early recurrent prostate cancer patients with PSA & lt; 0.2 ng/mL after radical prostatectomy
CONCLUSIONS: In BCR patients with PSA < 0.2 ng/mL, total-body [68Ga]Ga-PSMA-11 PET/CT not only demonstrated a significantly higher detection rate compared to SAFOV [68Ga]Ga-PSMA-11 PET/CT but also led to significant alterations in treatment regimens.PMID:38514483 | DOI:10.1007/s00259-024-06674-1 (Source: Molecular Medicine)
Source: Molecular Medicine - March 22, 2024 Category: Molecular Biology Authors: Yining Wang Liang Dong Haitao Zhao Lianghua Li Gang Huang Wei Xue Jianjun Liu Ruohua Chen Source Type: research
The superior detection rate of total-body [ < sup > 68 < /sup > Ga]Ga-PSMA-11 PET/CT compared to short axial field-of-view [ < sup > 68 < /sup > Ga]Ga-PSMA-11 PET/CT for early recurrent prostate cancer patients with PSA & lt; 0.2 ng/mL after radical prostatectomy
CONCLUSIONS: In BCR patients with PSA < 0.2 ng/mL, total-body [68Ga]Ga-PSMA-11 PET/CT not only demonstrated a significantly higher detection rate compared to SAFOV [68Ga]Ga-PSMA-11 PET/CT but also led to significant alterations in treatment regimens.PMID:38514483 | DOI:10.1007/s00259-024-06674-1 (Source: Molecular Medicine)
Source: Molecular Medicine - March 22, 2024 Category: Molecular Biology Authors: Yining Wang Liang Dong Haitao Zhao Lianghua Li Gang Huang Wei Xue Jianjun Liu Ruohua Chen Source Type: research
Transurethral surgical treatment for benign prostatic hyperplasia with detrusor underactivity: a systematic review and meta-analysis
ConclusionsOur meta-analysis results showed that transurethral surgery can improve the symptoms of BPH patients with DU. Surgery also showed advantages over pharmacological treatment for BPH patients with DU.Systematic review registrationPROSPERO CRD42023415188. (Source: Systematic Reviews)
Source: Systematic Reviews - March 22, 2024 Category: International Medicine & Public Health Source Type: research
Cancers, Vol. 16, Pages 1248: Prognostic Significance of the Cribriform Pattern in Prostate Cancer: Clinical Outcomes and Genomic Alterations
Conclusions: PC patients with CP4 have distinct genomic alterations and are at a high risk of disease progression following RP. Therefore, these patients may benefit from additional post-RP treatments and should be the subject of a prospective randomized clinical trial. (Source: Cancers)
Source: Cancers - March 22, 2024 Category: Cancer & Oncology Authors: Mutlay Sayan Yetkin Tuac Mahmut Akgul Grace K. Pratt Mary D. Rowan Dilara Akbulut Samet Kucukcolak Elza Tjio Shalini Moningi Jonathan E. Leeman Peter F. Orio Paul L. Nguyen Anthony V. D ’Amico Cagdas Aktan Tags: Article Source Type: research
Urinary incontinence rehabilitation of after radical prostatectomy: a systematic review and network meta-analysis
ConclusionIn general, all treatment methods improve the different stages of functional recovery of the pelvic floor muscles. However, in the long term, there are no significant differences between the treatments. Given the cost-effectiveness, pelvic floor muscle training + routine care + biofeedback + professional therapist–guided treatment + electrical nerve stimulation therapy within 3 months and pelvic floor muscle + routine care after 3 months may be a more economical option to treat urinary incontinence.Systematic review registrationhttps://www.crd.york.ac.uk/prospero/display_record.php?RecordID=331797, identifier C...
Source: Frontiers in Oncology - March 22, 2024 Category: Cancer & Oncology Source Type: research
The death of laparoscopy
ConclusionsThe study suggests a transformative shift towards robotic-assisted surgery, poised to dominate various minimally invasive procedures. The forecasts indicate that robotic surgery may surpass laparoscopy and open surgery in colectomies, proctectomies, pancreatectomies, and esophagectomies by 2025. This anticipated change emphasizes the need for proactive adjustments in surgical training programs to align with evolving surgical practices. The findings have substantial implications for future healthcare practices, necessitating a balance between traditional laparoscopy and the burgeoning role of robotic-assisted sur...
Source: Surgical Endoscopy - March 22, 2024 Category: Surgery Source Type: research
Erectile dysfunction criteria of 131,350 patients after open, laparoscopic, and robotic radical prostatectomy
ConclusionsThe reverse systematic review demonstrated that the robot-assisted radical prostatectomy showed higher rates of erectile function recovery at all times analyzed (1 –>18 months), in relation to the retropubic radical prostatectomy and laparoscopic radical prostatectomy. TheErection Sufficient for Intercourse criterion was the most used in the literature and showed the lowest bias capable of influencing the results and favoring any of the techniques and might be the fairest option for future comparisons. (Source: Andrology)
Source: Andrology - March 21, 2024 Category: Urology & Nephrology Authors: Tom ás Bernardo Costa Moretti,
Luís Alberto Magna,
Leonardo Oliveira Reis Tags: ORIGINAL ARTICLE Source Type: research
Develop prediction model to help forecast advanced prostate cancer patients ’ prognosis after surgery using neural network
ConclusionPatients with advanced prostate cancer may benefit from surgery. In order to forecast their overall survival, we first build a clinical features-based prognostic model. This model is accuracy and may offer some reference on clinical decision making. (Source: Frontiers in Endocrinology)
Source: Frontiers in Endocrinology - March 21, 2024 Category: Endocrinology Source Type: research
Development of Machine Learning Algorithm to Predict the Risk of Incontinence After Robot-Assisted Radical Prostatectomy
Journal of Endourology, Ahead of Print. (Source: Journal of Endourology)
Source: Journal of Endourology - March 21, 2024 Category: Urology & Nephrology Authors: Daniele Amparore Sabrina De Cillis Eugenio Alladio Michele Sica Federico Piramide Paolo Verri Enrico Checcucci Alberto Piana Alberto Quar à Edoardo Cisero Matteo Manfredi Michele Di Dio Cristian Fiori Francesco Porpiglia Source Type: research
Extended pelvic lymph node dissection during robotic prostatectomy: antegrade versus retrograde technique
Robot-assisted radical prostatectomy (RARP) with extended lymphadenectomy (ePLND) is the gold standard for surgical treatment of prostate cancer (PCa). Recently, the en-bloc ePLND has been proposed but no stud... (Source: BMC Urology)
Source: BMC Urology - March 21, 2024 Category: Urology & Nephrology Authors: Giancarlo Albo, Andrea Gallioli, Francesco Ripa, Elisa De Lorenzis, Luca Boeri, Carolina Bebi, Lorenzo Rocchini, Fabrizio Longo, Stefano Paolo Zanetti, Matteo Turetti, Michela Piccoli and Emanuele Montanari Tags: Research Source Type: research
Modified Retzius-sparing robot-assisted radical prostatectomy for cases with anterior tumor: a propensity score-matched analysis
ConclusionmRS-RARP seems to be an oncologically safe approach for patients with anterior PCa. Compared with the conventional approach, mRS-RARP approach shows benefits in the short-term postoperative UC recovery. (Source: World Journal of Urology)
Source: World Journal of Urology - March 20, 2024 Category: Urology & Nephrology Source Type: research
Can we predict pathology without surgery? Weighing the added value of multiparametric MRI and whole prostate radiomics in integrative machine learning models
ConclusionsOur results highlight the potential benefit of integrative ML models for pathological status prediction in PCa. Additional studies regarding clinical integration of such models can provide valuable information for personalizing therapy offering a tool to improve non-invasive prediction of pathological status.Clinical relevance statementThe best machine learning model was less prone to under-staging of the disease. The improved accuracy of our pathological prediction models could constitute an asset to the clinical workflow by providing clinicians with accurate pathological predictions prior to treatment.Key Poin...
Source: European Radiology - March 20, 2024 Category: Radiology Source Type: research
Impacts of Perioperative Comprehensive Nursing Intervention on Postoperative Urinary Incontinence and Quality of Life of Patients Undergoing Laparoscopic Radical Prostatectomy
Cancer Invest. 2024 Mar 19:1-10. doi: 10.1080/07357907.2024.2308173. Online ahead of print.ABSTRACTTo evaluate the impact of perioperative comprehensive nursing intervention on postoperative urinary incontinence, various aspects of patient well-being were assessed. The comprehensive group, that received the nursing intervention, demonstrated significant improvements in self-care skills, health knowledge level, self-care responsibility, and self-concept compared to the standard group. The findings indicate that perioperative comprehensive nursing intervention has a remarkable effect on patients undergoing laparoscopic radic...
Source: Cancer Investigation - March 19, 2024 Category: Cancer & Oncology Authors: Lulu Xin Jinjin Guo Source Type: research
Neoadjuvant chemohormonal therapy before radical prostatectomy in high-risk prostate cancer: a mini-review
Am J Clin Exp Urol. 2024 Feb 15;12(1):1-7. eCollection 2024.ABSTRACTHigh-risk localized prostate cancer (PCa) has the potential of recurrence and progression to a lethal phenotype, and neoadjuvant therapy followed by radical prostatectomy (RP) may be an option for these patients. Docetaxel has been recently shown to be an effective chemotherapeutic agent for high-volume metastatic hormone-sensitive PCa and metastatic castration-resistant PCa, and these increased efficacy create the impetus to assess the potential role of preoperative docetaxel in high-risk localized PCa. In this mini-review, we found that neoadjuvant chemo...
Source: Clinical Prostate Cancer - March 19, 2024 Category: Cancer & Oncology Authors: Junjie Fan Zhangdong Jiang Guojing Wang Dalin He Kaijie Wu Source Type: research
