Radical prostatectomy versus radiotherapy as local therapy for primary tumors in patients with oligometastatic prostate cancer
ConclusionTherefore, RP seems to be a possible treatment option for patients with omPC, exhibiting oncologic outcomes comparable to those with RT. (Source: Frontiers in Oncology)
Source: Frontiers in Oncology - March 13, 2024 Category: Cancer & Oncology Source Type: research

Clinical risk prediction model and external validation of positive surgical margin in laparoscopic radical prostatectomy based on MRI lesion location
ConclusionThe positive rate of surgical margin in middle PZ was significantly lower than that in other regions, and MRI lesion location was an independent risk factor for PSM. (Source: Clinical and Translational Oncology)
Source: Clinical and Translational Oncology - March 13, 2024 Category: Cancer & Oncology Source Type: research

Robot-assisted vs open retropubic radical prostatectomy: a propensity score-matched comparative analysis based on 15 years and 18,805 patients
ConclusionBoth RARP and ORP yielded similar oncological outcomes. RARP offered a slight advantage in terms of continence recovery, but its clinical significance may be less meaningful. RARP resulted in significantly improved postoperative EF, suggesting a potential influence of both surgical experience and minimally invasive approach. (Source: World Journal of Urology)
Source: World Journal of Urology - March 13, 2024 Category: Urology & Nephrology Source Type: research

Evaluating the relationship between contouring variability and modelled treatment outcome for prostate bed radiotherapy
This study focused on post-prostatectomy radiotherapy and aimed to 1) identify if there is a relationship between variations in commonly used contouring similarity metrics and resulting dosimetry and 2) identify the variation in clinical target volume (CTV) contouring that significantly impacts dosimetry.APPROACH: The study retrospectively analysed CT scans of 10 patients from the TROG 08.03 RAVES trial. The CTV, rectum, and bladder were contoured independently by three experienced observers. Using these contours reference simultaneous truth and performance level estimation (STAPLE) volumes were established. Additional CTV...
Source: Physics in Medicine and Biology - March 12, 2024 Category: Physics Authors: Viet Le Bao Annette Haworth Jason A Dowling Amy Walker Sankar Arumugam Michael Jameson Phillip Chlap Kirsty Wiltshire Sarah Keats Kirrily Cloak Mark Sidhom Andrew Kneebone Lois Holloway Source Type: research

Association between 3D membranous urethral parameters and urinary continence recovery after RARP
ConclusionThis clinical study shows that patients with larger MUV and longer MUL can return to UC earlier after surgery. Among that, eMUV is a better predictor. (Source: European Journal of Medical Research)
Source: European Journal of Medical Research - March 12, 2024 Category: Research Source Type: research

Correction: Utility of a penile compression device for the quality of life in male patients with urinary incontinence after prostatectomy (the MORE study): a randomized prospective study
(Source: BMC Research Notes)
Source: BMC Research Notes - March 12, 2024 Category: Research Authors: Daisuke Gotoh, Kazumasa Torimoto, Kenta Onishi, Yosuke Morizawa, Shunta Hori, Yasushi Nakai, Makito Miyake and Kiyohide Fujimoto Tags: Correction Source Type: research

Patients experience with the use of a penile clamp in post-prostatectomy incontinence - a prospective pilot study
CONCLUSION: The penile clamp shows promising results in reducing leakage with minimal risks of complications. It can be used as a treatment for patients awaiting surgery. However, patient selection is important regarding hand function, cognitive function and the penile anatomy.PMID:38462945 | DOI:10.2340/sju.v59.9586 (Source: Scandinavian Journal of Urology)
Source: Scandinavian Journal of Urology - March 11, 2024 Category: Urology & Nephrology Authors: Alexandru Jula Anders Andreasson Yr Logadottir Teresa Olsen Ekerhult Source Type: research

Late genitourinary toxicity in salvage radiotherapy for prostate cancer after radical prostatectomy: impact of daily fraction doses
CONCLUSION: The present results showed that ≥2.1 Gy/fraction resulted in a higher incidence of late grade ≥2 GU toxicity in SRT.ADVANCES IN KNOWLEDGE: The impact of fraction doses on late GU toxicity after SRT remains unknown. The results suggest that higher fraction doses may increase the risk of late GU toxicity in SRT.PMID:38466928 | DOI:10.1093/bjr/tqae055 (Source: The British Journal of Radiology)
Source: The British Journal of Radiology - March 11, 2024 Category: Radiology Authors: Seiya Takano Natsuo Tomita Taiki Takaoka Masanari Niwa Akira Torii Nozomi Kita Dai Okazaki Kaoru Uchiyama Mikiko Nakanishi-Imai Shiho Ayakawa Masato Iida Yusuke Tsuzuki Shinya Otsuka Yoshihiko Manabe Kento Nomura Yasutaka Ogawa Akifumi Miyakawa Akihiko Mi Source Type: research

Patients experience with the use of a penile clamp in post-prostatectomy incontinence - a prospective pilot study
CONCLUSION: The penile clamp shows promising results in reducing leakage with minimal risks of complications. It can be used as a treatment for patients awaiting surgery. However, patient selection is important regarding hand function, cognitive function and the penile anatomy.PMID:38462945 | DOI:10.2340/sju.v59.9586 (Source: Scandinavian Journal of Urology)
Source: Scandinavian Journal of Urology - March 11, 2024 Category: Urology & Nephrology Authors: Alexandru Jula Anders Andreasson Yr Logadottir Teresa Olsen Ekerhult Source Type: research

Late genitourinary toxicity in salvage radiotherapy for prostate cancer after radical prostatectomy: impact of daily fraction doses
CONCLUSION: The present results showed that ≥2.1 Gy/fraction resulted in a higher incidence of late grade ≥2 GU toxicity in SRT.ADVANCES IN KNOWLEDGE: The impact of fraction doses on late GU toxicity after SRT remains unknown. The results suggest that higher fraction doses may increase the risk of late GU toxicity in SRT.PMID:38466928 | DOI:10.1093/bjr/tqae055 (Source: The British Journal of Radiology)
Source: The British Journal of Radiology - March 11, 2024 Category: Radiology Authors: Seiya Takano Natsuo Tomita Taiki Takaoka Masanari Niwa Akira Torii Nozomi Kita Dai Okazaki Kaoru Uchiyama Mikiko Nakanishi-Imai Shiho Ayakawa Masato Iida Yusuke Tsuzuki Shinya Otsuka Yoshihiko Manabe Kento Nomura Yasutaka Ogawa Akifumi Miyakawa Akihiko Mi Source Type: research

Patients experience with the use of a penile clamp in post-prostatectomy incontinence - a prospective pilot study
CONCLUSION: The penile clamp shows promising results in reducing leakage with minimal risks of complications. It can be used as a treatment for patients awaiting surgery. However, patient selection is important regarding hand function, cognitive function and the penile anatomy.PMID:38462945 | DOI:10.2340/sju.v59.9586 (Source: Scandinavian Journal of Urology)
Source: Scandinavian Journal of Urology - March 11, 2024 Category: Urology & Nephrology Authors: Alexandru Jula Anders Andreasson Yr Logadottir Teresa Olsen Ekerhult Source Type: research

Morphologic features of prostate cancer-encased native vessels: An image analysis study
CONCLUSIONS: Similar to the 2000 study, increased media thickness and hypercellularity of vessels encased by PC were evident compared to controls. Borderline grade-dependent increased vessel cellularity changes were seen, suggesting a possible role in PC progression; the predictive value of these changes for outcome is uncertain. Whether the etiology of changes reflects locally increased intravascular pressure of vessels within tumor should be investigated.PMID:38461692 | DOI:10.1016/j.prp.2024.155239 (Source: Pathology, Research and Practice)
Source: Pathology, Research and Practice - March 10, 2024 Category: Pathology Authors: Cristina Fernandez Gonzalez De La Vega Savannah Duenweg Pragya Jain Sarah I Rubenstein Samuel Bobholz Michael J Barrett Peter S LaViolette Kenneth A Iczkowski Source Type: research

Morphologic features of prostate cancer-encased native vessels: An image analysis study
CONCLUSIONS: Similar to the 2000 study, increased media thickness and hypercellularity of vessels encased by PC were evident compared to controls. Borderline grade-dependent increased vessel cellularity changes were seen, suggesting a possible role in PC progression; the predictive value of these changes for outcome is uncertain. Whether the etiology of changes reflects locally increased intravascular pressure of vessels within tumor should be investigated.PMID:38461692 | DOI:10.1016/j.prp.2024.155239 (Source: Pathology, Research and Practice)
Source: Pathology, Research and Practice - March 10, 2024 Category: Pathology Authors: Cristina Fernandez Gonzalez De La Vega Savannah Duenweg Pragya Jain Sarah I Rubenstein Samuel Bobholz Michael J Barrett Peter S LaViolette Kenneth A Iczkowski Source Type: research