PSMA-PET helps plan treatment in men with relapsed prostate cancer
This study is an interim analysis on the use of PSMA-PET for managing patients, while the final readout of the primary endpoint -- whether the technique improves outcomes -- is planned for 2025, they noted. The researchers included a total of 178 with salvage RT plans available who had enrolled in the trial between September 2018 and August 2020 at UCLA and the University of California, San Francisco. They split 76 patients into a control arm and 102 to the PSMA-PET arm; fluciclovine-PET was used in 33 patients in the control arm. The main management change observed in the PSMA-PET arm was treatment escalation (addition ...
Source: AuntMinnie.com Headlines - January 31, 2024 Category: Radiology Authors: Will Morton Tags: Radiation Oncology/Therapy Source Type: news

Diagnostic Imaging Not Yet Enough for Biopsy-Free Radical Prostatectomy
(MedPage Today) -- While prostate-specific membrane antigen (PSMA)-PET may improve diagnostic accuracy in suspected prostate cancer, it may not be accurate enough to skip the biopsy when considering radical prostatectomy. In a retrospective review... (Source: MedPage Today Hematology/Oncology)
Source: MedPage Today Hematology/Oncology - November 27, 2023 Category: Hematology Source Type: news

PET tracer shows promise in prostate cancer patients
CHICAGO – Gallium-68 (Ga-68) RM2-PET/MRI is better than MRI alone for detecting relapse in prostate cancer patients, according to research presented November 26 at RSNA 2023. Moreover, the approach could help detect disease that other effective prostate cancer PET radiotracers may miss, said Heying Duan, MD, a nuclear medicine research scientist at Stanford University, during a November 26 scientific session. “You've hear a lot about PSMA. I wanted to introduce a new player in the game: gallium-68 GRPR antagonist,” Duan told attendees, during a scientific session on prostate cancer imaging. Several prostate-specif...
Source: AuntMinnie.com Headlines - November 26, 2023 Category: Radiology Authors: Will Morton Tags: Subspecialties Resources Genitourinary Radiology Nuclear Radiology Conference RSNA 2023 Source Type: news

Clarity, PSI enter agreement on phase III of SAR-bisPSMA trial
Clarity Pharmaceuticals, a clinical-stage radiopharmaceutical company, and PSI CRO, a global contract research organization, plan to conduct a trial using Clarity's phase III diagnostic trial of Clarify for prostate cancer patients.Clarify derives from PET imaging using copper-64 (Cu-64) SAR-bisPSMA in participants with high-risk prostate cancer prior to radical prostatectomy. It is a prospective, single-arm, multicenter, blinded-review, diagnostic performance study that will include 383 participants.The aim of the trial is to assess the diagnostic performance of Cu-64 SAR-bisPSMA PET to detect prostate cancer within lymp...
Source: AuntMinnie.com Headlines - October 26, 2023 Category: Radiology Authors: AuntMinnie.com staff writers Tags: Industry News Source Type: news

Observation, Not Radiotherapy, After Radical Prostatectomy Observation, Not Radiotherapy, After Radical Prostatectomy
The investigators observed no benefit to adjuvant radiotherapy after radical prostatectomy in patients with prostate cancer in the phase 3 RADICALS-RT trial.Medscape Medical News (Source: Medscape Hematology-Oncology Headlines)
Source: Medscape Hematology-Oncology Headlines - October 21, 2023 Category: Cancer & Oncology Tags: Hematology-Oncology News Source Type: news

Pelvic Muscle Training and Incontinence After Prostatectomy Pelvic Muscle Training and Incontinence After Prostatectomy
Could pelvic floor muscle training help improve the symptoms of post-prostatectomy stress urinary incontinence? A new study evaluated the therapeutic effects.Translational Andrology and Urology (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - September 7, 2023 Category: Consumer Health News Tags: Urology Journal Article Source Type: news

Presurgical MRI predicts cancer recurrence after prostatectomy
Preprostatectomy, MRI-based staging features perform comparably to postsurgica...Read more on AuntMinnie.comRelated Reading: AI developed for staging patients with prostate cancer PET/MRI emerges as a valuable theranostics technology ISMRM: Multiparametric MRI data interpretation varies among radiologists ISMRM: PET/MRI adds value in clinical cancer imaging SIR to host Capitol Hill briefing on prostate health (Source: AuntMinnie.com Headlines)
Source: AuntMinnie.com Headlines - July 5, 2023 Category: Radiology Source Type: news

Janssen to Highlight Scientific Advances and Commitment to Transform Cancer Care at ASCO and EHA with More than 90 Presentations Showcasing Robust, Differentiated Portfolio and Pipeline in Hematologic Malignancies and Solid Tumors
This study evaluates an investigational combination regimen of IMBRUVICA® (ibrutinib) plus venetoclax (I+V) for newly diagnosed chronic lymphocytic leukemia (CLL) and small lymphocytic lymphoma (SLL), (Abstracts #7535 and #P617, respectively).Advancing the Science of Solid Tumors Through Precision MedicineJanssen’s continued innovation in solid tumors focuses on advancing precision medicine options for patients with biomarker-driven disease who have limited targeted treatment options and moving patients into earlier lines of therapy when treatments may be more effective. Lung CancerAn oral presentation will report ...
Source: Johnson and Johnson - May 18, 2023 Category: Pharmaceuticals Tags: Innovation Source Type: news

rWT Does Not Improve Erectile Function After Prostatectomy rWT Does Not Improve Erectile Function After Prostatectomy
A study that looked at the outcomes of radial wave therapy for post-radical prostatectomy erectile dysfunction did not find substantial improvements with this therapy.Translational Andrology and Urology (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - May 8, 2023 Category: Consumer Health News Tags: Urology Journal Article Source Type: news

Initiating Salvage RT When PSA & gt;0.25 ng/mL Linked to All-Cause Mortality
FRIDAY, March 31, 2023 -- For men with one high-risk factor, initiating post-radical prostatectomy salvage radiation therapy (sRT) when prostate-specific antigen (PSA) levels are greater than 0.25 ng/mL is associated with an increased risk for... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - March 31, 2023 Category: Pharmaceuticals Source Type: news

Deaths From PSA-Detected Prostate Cancer Low at 15 Years, No Matter the Treatment
(MedPage Today) -- For prostate cancers detected by screening, cancer-specific mortality was low at 15-year follow-up regardless of whether patients underwent active monitoring, prostatectomy, or radiotherapy, results from the phase III randomized... (Source: MedPage Today Hematology/Oncology)
Source: MedPage Today Hematology/Oncology - March 12, 2023 Category: Hematology Source Type: news

Comparing Robot-Assisted and Laparoscopic Prostatectomy Comparing Robot-Assisted and Laparoscopic Prostatectomy
How do these two prostatectomy techniques compare in terms of safety, efficacy, and economic costs?Translational Andrology and Urology (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - February 27, 2023 Category: Consumer Health News Tags: Urology Journal Article Source Type: news

Escalated ADT Falls Short in Men With High-Risk Features After Prostatectomy
(MedPage Today) -- SAN FRANCISCO -- Add-on hormone therapy plus an antiandrogen to salvage radiation and androgen deprivation therapy (ADT) did not boost survival outcomes in high-risk prostate cancer. In the FORMULA-509 trial, the addition... (Source: MedPage Today Hematology/Oncology)
Source: MedPage Today Hematology/Oncology - February 18, 2023 Category: Hematology Source Type: news

Neoadjuvant Novel Hormonal Agents Studied in High-Risk Prostate Cancer
THURSDAY, Sept. 22, 2022 -- Neoadjuvant therapy with a novel hormonal agent prior to radical prostatectomy is associated with better outcomes for men with high-risk prostate cancer versus upfront radical prostatectomy, according to a study published... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - September 22, 2022 Category: Pharmaceuticals Source Type: news

Long-Term ADT With Radiation Helps Prevent Post-Prostatectomy Metastases
(MedPage Today) -- PARIS -- In men undergoing radiotherapy after radical prostatectomy, 2 years of androgen deprivation therapy (ADT) improved outcomes when compared with a shorter course of ADT, according to results from the RADICALS-HD trial... (Source: MedPage Today Hematology/Oncology)
Source: MedPage Today Hematology/Oncology - September 14, 2022 Category: Hematology Source Type: news