Clinical and imaging features of lymphomatosis cerebri: analysis of 8 cases and systematic review of the literature
AbstractLymphomatosis cerebri (LC) is a rare type of primary central nervous system lymphoma with diffuse, nonenhancing infiltrative lesions and is often misdiagnosed. Our study aimed to investigate the clinical characteristics and prognosis of LC through analyzing patients from the literature and our own center, so as to improve early diagnosis and treatment. PubMed, Web of Science and our hospital databases were reviewed, and information on demographic, clinical, pathological, cerebrospinal fluid (CSF), neuroimaging and treatment options was extracted. Univariate survival analysis was conducted by generating survival cur...
Source: Clinical and Experimental Medicine - November 18, 2023 Category: Research Source Type: research
Exosomal miR-200c and miR-141 as cerebrospinal fluid biopsy biomarkers for the response to chemotherapy in primary central nervous system lymphoma
ConclusionCollectively, miR-200c and miR-141 are likely to be upregulated in CSF exosomes after chemotherapy in patients with PCNSL, highlighting their potential as reliable liquid biopsy biomarkers for PCNSL diagnosis and chemotherapy efficacy monitoring. (Source: Hormones and Cancer)
Source: Hormones and Cancer - November 16, 2023 Category: Cancer & Oncology Source Type: research
Is reduced-dose whole-brain radiotherapy also feasible in primary CNS lymphoma for curative or salvage purpose?
ConclusionReduced-dose WBRT in curative and salvage treatments for PCNSL had no significant negative effect on the intracranial disease control rate or survival. Therefore, without impaired efficacy, use of reduced-dose WBRT appears promising for reduction of neurotoxicity. (Source: Journal of Neuro-Oncology)
Source: Journal of Neuro-Oncology - November 14, 2023 Category: Cancer & Oncology Source Type: research
A comprehensive overview of diagnosis, imaging and treatment of vitreoretinal lymphoma
Eur J Ophthalmol. 2023 Nov 13:11206721231211931. doi: 10.1177/11206721231211931. Online ahead of print.ABSTRACTVitreoretinal lymphoma (VRL) is a rare B-cell intraocular neoplasia characterized by poor long-term prognosis and lack of effective therapies. It mainly involves the vitreous humor, the retina, and the retinal pigment epithelium (RPE), although anterior segment involvement can occur. VRL is classified as a lymphoma of immune privileged sites, along with testis lymphoma and primary central nervous system lymphoma (PCNSL). VRL and PCNSL are strictly connected indeed: 80% of VRL develop PCNSL, while 20% of patients w...
Source: European Journal of Ophthalmology - November 13, 2023 Category: Opthalmology Authors: Matteo Menean Chiara Giuffr è Maria Vittoria Cicinelli Alessandro Marchese Giulio Modorati Francesco Bandello Elisabetta Miserocchi Source Type: research
Clonal hematopoiesis with TET2 mutations spawning synchronous primary central nervous system lymphoma and myelodysplastic syndrome
(Source: Annals of Hematology)
Source: Annals of Hematology - November 11, 2023 Category: Hematology Source Type: research
Associations between BMI in youth and site-specific cancer in men-A cohort study with register linkage
CONCLUSIONS: This study reports linear associations between BMI at age 18 and subsequent site-specific cancers, calling for rapid action to stem the obesity epidemic and to prepare the health care system for steep increases in cancer cases.PMID:37927128 | DOI:10.1002/oby.23942 (Source: Obesity)
Source: Obesity - November 6, 2023 Category: Eating Disorders & Weight Management Authors: Aron Onerup Kirsten Mehlig Agnes Af Geijerstam Elin Ekblom-Bak Hans-Georg Kuhn Lauren Lissner Annika Rosengren Mats B örjesson Maria Åberg Source Type: research
Associations between BMI in youth and site-specific cancer in men-A cohort study with register linkage
CONCLUSIONS: This study reports linear associations between BMI at age 18 and subsequent site-specific cancers, calling for rapid action to stem the obesity epidemic and to prepare the health care system for steep increases in cancer cases.PMID:37927128 | DOI:10.1002/oby.23942 (Source: Obesity)
Source: Obesity - November 6, 2023 Category: Eating Disorders & Weight Management Authors: Aron Onerup Kirsten Mehlig Agnes Af Geijerstam Elin Ekblom-Bak Hans-Georg Kuhn Lauren Lissner Annika Rosengren Mats B örjesson Maria Åberg Source Type: research
Associations between BMI in youth and site-specific cancer in men-A cohort study with register linkage
CONCLUSIONS: This study reports linear associations between BMI at age 18 and subsequent site-specific cancers, calling for rapid action to stem the obesity epidemic and to prepare the health care system for steep increases in cancer cases.PMID:37927128 | DOI:10.1002/oby.23942 (Source: Obesity)
Source: Obesity - November 6, 2023 Category: Eating Disorders & Weight Management Authors: Aron Onerup Kirsten Mehlig Agnes Af Geijerstam Elin Ekblom-Bak Hans-Georg Kuhn Lauren Lissner Annika Rosengren Mats B örjesson Maria Åberg Source Type: research
Associations between BMI in youth and site-specific cancer in men-A cohort study with register linkage
CONCLUSIONS: This study reports linear associations between BMI at age 18 and subsequent site-specific cancers, calling for rapid action to stem the obesity epidemic and to prepare the health care system for steep increases in cancer cases.PMID:37927128 | DOI:10.1002/oby.23942 (Source: Obesity)
Source: Obesity - November 6, 2023 Category: Eating Disorders & Weight Management Authors: Aron Onerup Kirsten Mehlig Agnes Af Geijerstam Elin Ekblom-Bak Hans-Georg Kuhn Lauren Lissner Annika Rosengren Mats B örjesson Maria Åberg Source Type: research
Associations between BMI in youth and site-specific cancer in men-A cohort study with register linkage
CONCLUSIONS: This study reports linear associations between BMI at age 18 and subsequent site-specific cancers, calling for rapid action to stem the obesity epidemic and to prepare the health care system for steep increases in cancer cases.PMID:37927128 | DOI:10.1002/oby.23942 (Source: Obesity)
Source: Obesity - November 6, 2023 Category: Eating Disorders & Weight Management Authors: Aron Onerup Kirsten Mehlig Agnes Af Geijerstam Elin Ekblom-Bak Hans-Georg Kuhn Lauren Lissner Annika Rosengren Mats B örjesson Maria Åberg Source Type: research
Associations between BMI in youth and site-specific cancer in men-A cohort study with register linkage
CONCLUSIONS: This study reports linear associations between BMI at age 18 and subsequent site-specific cancers, calling for rapid action to stem the obesity epidemic and to prepare the health care system for steep increases in cancer cases.PMID:37927128 | DOI:10.1002/oby.23942 (Source: Obesity)
Source: Obesity - November 6, 2023 Category: Eating Disorders & Weight Management Authors: Aron Onerup Kirsten Mehlig Agnes Af Geijerstam Elin Ekblom-Bak Hans-Georg Kuhn Lauren Lissner Annika Rosengren Mats B örjesson Maria Åberg Source Type: research
Associations between BMI in youth and site-specific cancer in men-A cohort study with register linkage
CONCLUSIONS: This study reports linear associations between BMI at age 18 and subsequent site-specific cancers, calling for rapid action to stem the obesity epidemic and to prepare the health care system for steep increases in cancer cases.PMID:37927128 | DOI:10.1002/oby.23942 (Source: Obesity)
Source: Obesity - November 6, 2023 Category: Eating Disorders & Weight Management Authors: Aron Onerup Kirsten Mehlig Agnes Af Geijerstam Elin Ekblom-Bak Hans-Georg Kuhn Lauren Lissner Annika Rosengren Mats B örjesson Maria Åberg Source Type: research
Prognosis, Risk Factors and Clinical Features of Intraocular Recurrence in Primary Vitreoretinal Lymphoma
CONCLUSIONS: This study did not identify an impact of intraocular recurrence on CNS manifestations or survival outcomes in patients with PVRL. Younger patients have a higher risk of intraocular recurrence, and combined systemic and intravitreal chemotherapy may reduce intraocular recurrence. Regular ophthalmic follow-up and IL-10 testing are recommended to detect intraocular recurrence.PMID:37918656 | DOI:10.1016/j.oret.2023.10.021 (Source: Cancer Control)
Source: Cancer Control - November 2, 2023 Category: Cancer & Oncology Authors: Shixue Liu Tingting Jiang Junxiang Gu Xinyi Zhou Wenwen Chen Bo Ping Yuhong Zhou Ting Zhang Xin Huang Gezhi Xu Qing Chang Source Type: research
Cancers, Vol. 15, Pages 5266: Functional Outcome and Overall Survival in Patients with Primary or Secondary CNS Lymphoma after Surgical Resection vs. Biopsy
Conclusions: Our data show a favourable outcome when resection is compared to either stereotactic or open biopsy. Additionally, the marginally improved postoperative functional status observed in patients who underwent resection, as opposed to in those who underwent biopsy, provides further evidence in favour of the advantages of surgical resection for enhancing neurological deficits. (Source: Cancers)
Source: Cancers - November 2, 2023 Category: Cancer & Oncology Authors: Franziska Staub-Bartelt Jos Rittenauer Michael Sabel Marion Rapp Tags: Article Source Type: research
