Machine learning-based pathomics signature of histology slides as a novel prognostic indicator in primary central nervous system lymphoma
ConclusionAs a novel, non-invasive, and convenient approach, the newly developed pathomics signature is a powerful predictor of OS and PFS in PCNSL and might be a potential predictive indicator for therapeutic response. (Source: Journal of Neuro-Oncology)
Source: Journal of Neuro-Oncology - April 1, 2024 Category: Cancer & Oncology Source Type: research
Elderly long-term survivors in the Nordic phase II study with first-line maintenance temozolomide for primary central nervous system lymphoma: a 10-year follow-up
Haematologica. 2024 Mar 28. doi: 10.3324/haematol.2024.285207. Online ahead of print.ABSTRACTNot available.PMID:38546689 | DOI:10.3324/haematol.2024.285207 (Source: Haematologica)
Source: Haematologica - March 28, 2024 Category: Hematology Authors: Elisa Jacobsen Pulczynski Mikkel Runason Simonsen Outi Kuittinen Unn-Merete Fagerli Martin Erlanson Øystein Fluge Sirpa Lepp ä Bj ørn Østenstad Alexander Foss å Mikael Eriksson Tarec El-Galaly Hanne Kuitunen Karin Papworth Maria Ljungqvist Martin B P Source Type: research
Elderly long-term survivors in the Nordic phase II study with first-line maintenance temozolomide for primary central nervous system lymphoma: a 10-year follow-up
Haematologica. 2024 Mar 28. doi: 10.3324/haematol.2024.285207. Online ahead of print.ABSTRACTNot available.PMID:38546689 | DOI:10.3324/haematol.2024.285207 (Source: Haematologica)
Source: Haematologica - March 28, 2024 Category: Hematology Authors: Elisa Jacobsen Pulczynski Mikkel Runason Simonsen Outi Kuittinen Unn-Merete Fagerli Martin Erlanson Øystein Fluge Sirpa Lepp ä Bj ørn Østenstad Alexander Foss å Mikael Eriksson Tarec El-Galaly Hanne Kuitunen Karin Papworth Maria Ljungqvist Martin B P Source Type: research
Elderly long-term survivors in the Nordic phase II study with first-line maintenance temozolomide for primary central nervous system lymphoma: a 10-year follow-up
Haematologica. 2024 Mar 28. doi: 10.3324/haematol.2024.285207. Online ahead of print.ABSTRACTNot available.PMID:38546689 | DOI:10.3324/haematol.2024.285207 (Source: Haematologica)
Source: Haematologica - March 28, 2024 Category: Hematology Authors: Elisa Jacobsen Pulczynski Mikkel Runason Simonsen Outi Kuittinen Unn-Merete Fagerli Martin Erlanson Øystein Fluge Sirpa Lepp ä Bj ørn Østenstad Alexander Foss å Mikael Eriksson Tarec El-Galaly Hanne Kuitunen Karin Papworth Maria Ljungqvist Martin B P Source Type: research
Elderly long-term survivors in the Nordic phase II study with first-line maintenance temozolomide for primary central nervous system lymphoma: a 10-year follow-up
Haematologica. 2024 Mar 28. doi: 10.3324/haematol.2024.285207. Online ahead of print.ABSTRACTNot available.PMID:38546689 | DOI:10.3324/haematol.2024.285207 (Source: Haematologica)
Source: Haematologica - March 28, 2024 Category: Hematology Authors: Elisa Jacobsen Pulczynski Mikkel Runason Simonsen Outi Kuittinen Unn-Merete Fagerli Martin Erlanson Øystein Fluge Sirpa Lepp ä Bj ørn Østenstad Alexander Foss å Mikael Eriksson Tarec El-Galaly Hanne Kuitunen Karin Papworth Maria Ljungqvist Martin B P Source Type: research
Gamma-delta T-cell lymphoma of the central nervous system: A case report and review of the literature
We describe a case of TCL presenting in the basal ganglia with γδ receptor expression and a remarkably aggressive clinical course. To the best of our knowledge, this is the fifth reported case of γδ TCL presenting in the CNS. We review existing literature, including the previously reported cases of γδ TCL of the CNS. In our case, a 69-year-old male presented with acute onset dysarthria and right-sided weakness, with initial imaging concerning for stroke. Repeat imaging demonstrated a 2.6-cm mass in the left basal ganglia-corona radiata. Pathologic examination of a stereotactic biopsy revealed TCL with γδ receptor p...
Source: Clinical Neuropathology - March 22, 2024 Category: Pathology Authors: Alexa T Andre Meagan Chambers Daniel E Sabath Source Type: research
Gamma-delta T-cell lymphoma of the central nervous system: A case report and review of the literature
We describe a case of TCL presenting in the basal ganglia with γδ receptor expression and a remarkably aggressive clinical course. To the best of our knowledge, this is the fifth reported case of γδ TCL presenting in the CNS. We review existing literature, including the previously reported cases of γδ TCL of the CNS. In our case, a 69-year-old male presented with acute onset dysarthria and right-sided weakness, with initial imaging concerning for stroke. Repeat imaging demonstrated a 2.6-cm mass in the left basal ganglia-corona radiata. Pathologic examination of a stereotactic biopsy revealed TCL with γδ receptor p...
Source: Clinical Neuropathology - March 22, 2024 Category: Pathology Authors: Alexa T Andre Meagan Chambers Daniel E Sabath Source Type: research
Gamma-delta T-cell lymphoma of the central nervous system: A case report and review of the literature
We describe a case of TCL presenting in the basal ganglia with γδ receptor expression and a remarkably aggressive clinical course. To the best of our knowledge, this is the fifth reported case of γδ TCL presenting in the CNS. We review existing literature, including the previously reported cases of γδ TCL of the CNS. In our case, a 69-year-old male presented with acute onset dysarthria and right-sided weakness, with initial imaging concerning for stroke. Repeat imaging demonstrated a 2.6-cm mass in the left basal ganglia-corona radiata. Pathologic examination of a stereotactic biopsy revealed TCL with γδ receptor p...
Source: Clinical Neuropathology - March 22, 2024 Category: Pathology Authors: Alexa T Andre Meagan Chambers Daniel E Sabath Source Type: research
Gamma-delta T-cell lymphoma of the central nervous system: A case report and review of the literature
We describe a case of TCL presenting in the basal ganglia with γδ receptor expression and a remarkably aggressive clinical course. To the best of our knowledge, this is the fifth reported case of γδ TCL presenting in the CNS. We review existing literature, including the previously reported cases of γδ TCL of the CNS. In our case, a 69-year-old male presented with acute onset dysarthria and right-sided weakness, with initial imaging concerning for stroke. Repeat imaging demonstrated a 2.6-cm mass in the left basal ganglia-corona radiata. Pathologic examination of a stereotactic biopsy revealed TCL with γδ receptor p...
Source: Clinical Neuropathology - March 22, 2024 Category: Pathology Authors: Alexa T Andre Meagan Chambers Daniel E Sabath Source Type: research
Gamma-delta T-cell lymphoma of the central nervous system: A case report and review of the literature
We describe a case of TCL presenting in the basal ganglia with γδ receptor expression and a remarkably aggressive clinical course. To the best of our knowledge, this is the fifth reported case of γδ TCL presenting in the CNS. We review existing literature, including the previously reported cases of γδ TCL of the CNS. In our case, a 69-year-old male presented with acute onset dysarthria and right-sided weakness, with initial imaging concerning for stroke. Repeat imaging demonstrated a 2.6-cm mass in the left basal ganglia-corona radiata. Pathologic examination of a stereotactic biopsy revealed TCL with γδ receptor p...
Source: Clinical Neuropathology - March 22, 2024 Category: Pathology Authors: Alexa T Andre Meagan Chambers Daniel E Sabath Source Type: research
Gamma-delta T-cell lymphoma of the central nervous system: A case report and review of the literature
We describe a case of TCL presenting in the basal ganglia with γδ receptor expression and a remarkably aggressive clinical course. To the best of our knowledge, this is the fifth reported case of γδ TCL presenting in the CNS. We review existing literature, including the previously reported cases of γδ TCL of the CNS. In our case, a 69-year-old male presented with acute onset dysarthria and right-sided weakness, with initial imaging concerning for stroke. Repeat imaging demonstrated a 2.6-cm mass in the left basal ganglia-corona radiata. Pathologic examination of a stereotactic biopsy revealed TCL with γδ receptor p...
Source: Clinical Neuropathology - March 22, 2024 Category: Pathology Authors: Alexa T Andre Meagan Chambers Daniel E Sabath Source Type: research
Gamma-delta T-cell lymphoma of the central nervous system: A case report and review of the literature
We describe a case of TCL presenting in the basal ganglia with γδ receptor expression and a remarkably aggressive clinical course. To the best of our knowledge, this is the fifth reported case of γδ TCL presenting in the CNS. We review existing literature, including the previously reported cases of γδ TCL of the CNS. In our case, a 69-year-old male presented with acute onset dysarthria and right-sided weakness, with initial imaging concerning for stroke. Repeat imaging demonstrated a 2.6-cm mass in the left basal ganglia-corona radiata. Pathologic examination of a stereotactic biopsy revealed TCL with γδ receptor p...
Source: Clinical Neuropathology - March 22, 2024 Category: Pathology Authors: Alexa T Andre Meagan Chambers Daniel E Sabath Source Type: research
Gamma-delta T-cell lymphoma of the central nervous system: A case report and review of the literature
We describe a case of TCL presenting in the basal ganglia with γδ receptor expression and a remarkably aggressive clinical course. To the best of our knowledge, this is the fifth reported case of γδ TCL presenting in the CNS. We review existing literature, including the previously reported cases of γδ TCL of the CNS. In our case, a 69-year-old male presented with acute onset dysarthria and right-sided weakness, with initial imaging concerning for stroke. Repeat imaging demonstrated a 2.6-cm mass in the left basal ganglia-corona radiata. Pathologic examination of a stereotactic biopsy revealed TCL with γδ receptor p...
Source: Clinical Neuropathology - March 22, 2024 Category: Pathology Authors: Alexa T Andre Meagan Chambers Daniel E Sabath Source Type: research
Gamma-delta T-cell lymphoma of the central nervous system: A case report and review of the literature
We describe a case of TCL presenting in the basal ganglia with γδ receptor expression and a remarkably aggressive clinical course. To the best of our knowledge, this is the fifth reported case of γδ TCL presenting in the CNS. We review existing literature, including the previously reported cases of γδ TCL of the CNS. In our case, a 69-year-old male presented with acute onset dysarthria and right-sided weakness, with initial imaging concerning for stroke. Repeat imaging demonstrated a 2.6-cm mass in the left basal ganglia-corona radiata. Pathologic examination of a stereotactic biopsy revealed TCL with γδ receptor p...
Source: Clinical Neuropathology - March 22, 2024 Category: Pathology Authors: Alexa T Andre Meagan Chambers Daniel E Sabath Source Type: research
Gamma-delta T-cell lymphoma of the central nervous system: A case report and review of the literature
We describe a case of TCL presenting in the basal ganglia with γδ receptor expression and a remarkably aggressive clinical course. To the best of our knowledge, this is the fifth reported case of γδ TCL presenting in the CNS. We review existing literature, including the previously reported cases of γδ TCL of the CNS. In our case, a 69-year-old male presented with acute onset dysarthria and right-sided weakness, with initial imaging concerning for stroke. Repeat imaging demonstrated a 2.6-cm mass in the left basal ganglia-corona radiata. Pathologic examination of a stereotactic biopsy revealed TCL with γδ receptor p...
Source: Clinical Neuropathology - March 22, 2024 Category: Pathology Authors: Alexa T Andre Meagan Chambers Daniel E Sabath Source Type: research
