C-reactive protein levels, the prognostic nutritional index, and the lactate dehydrogenase-to-lymphocyte ratio are important prognostic factors in primary central nervous system lymphoma: a single-center study of 223 patients
AbstractPrimary central nervous system lymphoma (PCNSL) is a rare and highly aggressive type of extranodal non-Hodgkin lymphoma (NHL), and the prognosis is poor. Currently, the most used prognostic models are the Memorial Sloan-Kettering Cancer Center (MSKCC) and International Extranodal Lymphoma Study Group (IELSG) scores; however, their predictive effects are changing with increasing incidence and changing treatment regimens. A growing body of evidence has demonstrated that inflammatory and nutritional markers are factors that can determine tumor prognosis. Therefore, the aim of this study was to identify and validate no...
Source: Neurosurgical Review - December 19, 2023 Category: Neurosurgery Source Type: research
Primary central nervous system lymphoma
AbstractPrimary central nervous system lymphoma (PCNSL) is a rare type of non-Hodgkin lymphoma (NHL) manifesting in the brain, spinal cord, cerebrospinal fluid and/or eyes, in the absence of systemic manifestations. With an increasing incidence and a 30% 5-year overall survival if promptly treated, timely diagnosis and subsequent treatment is paramount. The typical MRI appearance for PCNSL is a solitary or multiple T2-hypointense, homogeneous gadolinium-enhancing lesion with restricted diffusion. Dexamethasone treatment might compromise and delay the diagnosis. Hallmark of treatment is induction with intravenous high-dose ...
Source: Journal of Neurology - December 19, 2023 Category: Neurology Source Type: research
The role of PET/CT in the central nervous system tumours
Magy Onkol. 2023 Dec 18;67(4):321-331. Epub 2023 Oct 6.ABSTRACTThe appearance of hybrid imaging, including PET/CT has been a huge milestone not only in the development of nuclear medicine but of the whole medical imaging. The examination with 18F-FDG, the most frequently used radiopharmaceutical has become for now one of the most important diagnostic tools in oncological patient care, applied with numerous indication goals. However, the depiction of central nervous system malignancies, especially those of the brain, with FDG PET has limitations due to high cerebral background activity, it can be used primarily in lymphoma ...
Source: Magyar Onkologia - December 18, 2023 Category: Cancer & Oncology Authors: P éter Szabó Source Type: research
Molecular Analysis of Liquid Vitreous Biopsy Reveals Occult Lymphoma Following Cytology-Negative Biopsies of the Brain and Vitreous
CONCLUSION: This case illustrates the unique contribution of liquid biopsy neuropathology-oriented molecular testing in a challenging case with high clinical suspicion of PCNSL in which gold-standard diagnostic testing failed to yield a diagnosis.PMID:38109211 | DOI:10.1080/09273948.2023.2287061 (Source: Ocular Immunology and Inflammation)
Source: Ocular Immunology and Inflammation - December 18, 2023 Category: Allergy & Immunology Authors: Daniel A Balikov Kyle Conway Noah A Brown Sandra Camelo-Piragua Rajesh C Rao Source Type: research
The role of PET/CT in the central nervous system tumours
Magy Onkol. 2023 Dec 18;67(4):321-331. Epub 2023 Oct 6.ABSTRACTThe appearance of hybrid imaging, including PET/CT has been a huge milestone not only in the development of nuclear medicine but of the whole medical imaging. The examination with 18F-FDG, the most frequently used radiopharmaceutical has become for now one of the most important diagnostic tools in oncological patient care, applied with numerous indication goals. However, the depiction of central nervous system malignancies, especially those of the brain, with FDG PET has limitations due to high cerebral background activity, it can be used primarily in lymphoma ...
Source: Magyar Onkologia - December 18, 2023 Category: Cancer & Oncology Authors: P éter Szabó Source Type: research
Molecular Analysis of Liquid Vitreous Biopsy Reveals Occult Lymphoma Following Cytology-Negative Biopsies of the Brain and Vitreous
CONCLUSION: This case illustrates the unique contribution of liquid biopsy neuropathology-oriented molecular testing in a challenging case with high clinical suspicion of PCNSL in which gold-standard diagnostic testing failed to yield a diagnosis.PMID:38109211 | DOI:10.1080/09273948.2023.2287061 (Source: Ocular Immunology and Inflammation)
Source: Ocular Immunology and Inflammation - December 18, 2023 Category: Allergy & Immunology Authors: Daniel A Balikov Kyle Conway Noah A Brown Sandra Camelo-Piragua Rajesh C Rao Source Type: research
The role of PET/CT in the central nervous system tumours
Magy Onkol. 2023 Dec 18;67(4):321-331. Epub 2023 Oct 6.ABSTRACTThe appearance of hybrid imaging, including PET/CT has been a huge milestone not only in the development of nuclear medicine but of the whole medical imaging. The examination with 18F-FDG, the most frequently used radiopharmaceutical has become for now one of the most important diagnostic tools in oncological patient care, applied with numerous indication goals. However, the depiction of central nervous system malignancies, especially those of the brain, with FDG PET has limitations due to high cerebral background activity, it can be used primarily in lymphoma ...
Source: Magyar Onkologia - December 18, 2023 Category: Cancer & Oncology Authors: P éter Szabó Source Type: research
Molecular Analysis of Liquid Vitreous Biopsy Reveals Occult Lymphoma Following Cytology-Negative Biopsies of the Brain and Vitreous
CONCLUSION: This case illustrates the unique contribution of liquid biopsy neuropathology-oriented molecular testing in a challenging case with high clinical suspicion of PCNSL in which gold-standard diagnostic testing failed to yield a diagnosis.PMID:38109211 | DOI:10.1080/09273948.2023.2287061 (Source: Ocular Immunology and Inflammation)
Source: Ocular Immunology and Inflammation - December 18, 2023 Category: Allergy & Immunology Authors: Daniel A Balikov Kyle Conway Noah A Brown Sandra Camelo-Piragua Rajesh C Rao Source Type: research
The role of PET/CT in the central nervous system tumours
Magy Onkol. 2023 Dec 18;67(4):321-331. Epub 2023 Oct 6.ABSTRACTThe appearance of hybrid imaging, including PET/CT has been a huge milestone not only in the development of nuclear medicine but of the whole medical imaging. The examination with 18F-FDG, the most frequently used radiopharmaceutical has become for now one of the most important diagnostic tools in oncological patient care, applied with numerous indication goals. However, the depiction of central nervous system malignancies, especially those of the brain, with FDG PET has limitations due to high cerebral background activity, it can be used primarily in lymphoma ...
Source: Magyar Onkologia - December 18, 2023 Category: Cancer & Oncology Authors: P éter Szabó Source Type: research
The role of PET/CT in the central nervous system tumours
Magy Onkol. 2023 Dec 18;67(4):321-331. Epub 2023 Oct 6.ABSTRACTThe appearance of hybrid imaging, including PET/CT has been a huge milestone not only in the development of nuclear medicine but of the whole medical imaging. The examination with 18F-FDG, the most frequently used radiopharmaceutical has become for now one of the most important diagnostic tools in oncological patient care, applied with numerous indication goals. However, the depiction of central nervous system malignancies, especially those of the brain, with FDG PET has limitations due to high cerebral background activity, it can be used primarily in lymphoma ...
Source: Magyar Onkologia - December 18, 2023 Category: Cancer & Oncology Authors: P éter Szabó Source Type: research
The role of PET/CT in the central nervous system tumours
Magy Onkol. 2023 Dec 18;67(4):321-331. Epub 2023 Oct 6.ABSTRACTThe appearance of hybrid imaging, including PET/CT has been a huge milestone not only in the development of nuclear medicine but of the whole medical imaging. The examination with 18F-FDG, the most frequently used radiopharmaceutical has become for now one of the most important diagnostic tools in oncological patient care, applied with numerous indication goals. However, the depiction of central nervous system malignancies, especially those of the brain, with FDG PET has limitations due to high cerebral background activity, it can be used primarily in lymphoma ...
Source: Magyar Onkologia - December 18, 2023 Category: Cancer & Oncology Authors: P éter Szabó Source Type: research
The role of PET/CT in the central nervous system tumours
Magy Onkol. 2023 Dec 18;67(4):321-331. Epub 2023 Oct 6.ABSTRACTThe appearance of hybrid imaging, including PET/CT has been a huge milestone not only in the development of nuclear medicine but of the whole medical imaging. The examination with 18F-FDG, the most frequently used radiopharmaceutical has become for now one of the most important diagnostic tools in oncological patient care, applied with numerous indication goals. However, the depiction of central nervous system malignancies, especially those of the brain, with FDG PET has limitations due to high cerebral background activity, it can be used primarily in lymphoma ...
Source: Magyar Onkologia - December 18, 2023 Category: Cancer & Oncology Authors: P éter Szabó Source Type: research
The role of PET/CT in the central nervous system tumours
Magy Onkol. 2023 Dec 18;67(4):321-331. Epub 2023 Oct 6.ABSTRACTThe appearance of hybrid imaging, including PET/CT has been a huge milestone not only in the development of nuclear medicine but of the whole medical imaging. The examination with 18F-FDG, the most frequently used radiopharmaceutical has become for now one of the most important diagnostic tools in oncological patient care, applied with numerous indication goals. However, the depiction of central nervous system malignancies, especially those of the brain, with FDG PET has limitations due to high cerebral background activity, it can be used primarily in lymphoma ...
Source: Magyar Onkologia - December 18, 2023 Category: Cancer & Oncology Authors: P éter Szabó Source Type: research
The role of PET/CT in the central nervous system tumours
Magy Onkol. 2023 Dec 18;67(4):321-331. Epub 2023 Oct 6.ABSTRACTThe appearance of hybrid imaging, including PET/CT has been a huge milestone not only in the development of nuclear medicine but of the whole medical imaging. The examination with 18F-FDG, the most frequently used radiopharmaceutical has become for now one of the most important diagnostic tools in oncological patient care, applied with numerous indication goals. However, the depiction of central nervous system malignancies, especially those of the brain, with FDG PET has limitations due to high cerebral background activity, it can be used primarily in lymphoma ...
Source: Magyar Onkologia - December 18, 2023 Category: Cancer & Oncology Authors: P éter Szabó Source Type: research
The role of PET/CT in the central nervous system tumours
Magy Onkol. 2023 Dec 18;67(4):321-331. Epub 2023 Oct 6.ABSTRACTThe appearance of hybrid imaging, including PET/CT has been a huge milestone not only in the development of nuclear medicine but of the whole medical imaging. The examination with 18F-FDG, the most frequently used radiopharmaceutical has become for now one of the most important diagnostic tools in oncological patient care, applied with numerous indication goals. However, the depiction of central nervous system malignancies, especially those of the brain, with FDG PET has limitations due to high cerebral background activity, it can be used primarily in lymphoma ...
Source: Magyar Onkologia - December 18, 2023 Category: Cancer & Oncology Authors: P éter Szabó Source Type: research
