Polyethylene Glycol Research This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Isopropanol-promoted DNA extraction by polydopamine functionalized magnetic particles based on metal coordination
Talanta. 2024 Apr 17;275:126115. doi: 10.1016/j.talanta.2024.126115. Online ahead of print.ABSTRACTHigh-quality DNA is an important guarantee to start downstream experiments in many biological and medical research areas. Magnetic particle-based DNA extraction methods from blood mainly depend on electrostatic adsorption in a low-pH environment. However, the strong acidic environment can influence the DNA stability. Herein, a polydopamine-functionalized magnetic particle (PDA@Fe3O4)-based protocol was developed for DNA extraction from whole blood samples. In the protocol, Mg2+ and Ca2+ were utilized to bridge the adsorption ...
Source: Talanta - April 25, 2024 Category: Chemistry Authors: Wenjuan Yang Xiaoxiao Pu Wenting Xie Ling Li Zixuan Ding Li Jia Source Type: research

Comparison between a single dose of PEG G-CSF and multiple doses of non-PEG G-CSF: a systematic review and meta-analysis from Clinical Practice Guidelines for the use of G-CSF 2022
CONCLUSIONS: A single dose of PEG G-CSF is strongly recommended over multiple-dose non-PEG G-CSF therapy for the primary prophylaxis of FN.PMID:38649648 | DOI:10.1007/s10147-024-02504-4 (Source: Clinical Breast Cancer)
Source: Clinical Breast Cancer - April 22, 2024 Category: Cancer & Oncology Authors: Tetsuhiro Yoshinami Kazuki Nozawa Takamichi Yokoe Yukinori Ozaki Hiroshi Nishio Kenji Tsuchihashi Eiki Ichihara Yuji Miura Makoto Endo Shingo Yano Dai Maruyama Nobuyuki Susumu Munetaka Takekuma Takashi Motohashi Mamoru Ito Eishi Baba Nobuaki Ochi Toshio K Source Type: research

Comparison between a single dose of PEG G-CSF and multiple doses of non-PEG G-CSF: a systematic review and meta-analysis from Clinical Practice Guidelines for the use of G-CSF 2022
CONCLUSIONS: A single dose of PEG G-CSF is strongly recommended over multiple-dose non-PEG G-CSF therapy for the primary prophylaxis of FN.PMID:38649648 | DOI:10.1007/s10147-024-02504-4 (Source: Clinical Genitourinary Cancer)
Source: Clinical Genitourinary Cancer - April 22, 2024 Category: Cancer & Oncology Authors: Tetsuhiro Yoshinami Kazuki Nozawa Takamichi Yokoe Yukinori Ozaki Hiroshi Nishio Kenji Tsuchihashi Eiki Ichihara Yuji Miura Makoto Endo Shingo Yano Dai Maruyama Nobuyuki Susumu Munetaka Takekuma Takashi Motohashi Mamoru Ito Eishi Baba Nobuaki Ochi Toshio K Source Type: research

Host ‐Guest Interaction Mediated Interfacial Co‐Assembly of Cyclodextrin and Bottlebrush Surfactants for Precisely Tunable Photonic Supraballs
Precisely tunable photonic supraballs are achieved through the host-guest interaction betweenα-cyclodextrin and bottlebrush block copolymer at oil-water interfaces during organized spontaneous emulsification (OSE) process. The increased asymmetry of BBCP molecules, resulting from the complexation ofα-CD and PEG within BBCPs, induces increased spherical curvature of internal droplets, leading to a distinct blueshift of structural color. AbstractInvestigations of host-guest interactions at water-oil (w/o) interfaces are limited in single emulsion systems producing simple self-assembled objects with limited uses. Here, with...
Source: Small - April 22, 2024 Category: Nanotechnology Authors: Dezhi Liu, Zhenli Zhang, Kunyu Zhang, Yuesheng Li, Dong ‐Po Song Tags: Research Article Source Type: research

Swift Covalent Gelation Coupled with Robust Wet Adhesive Powder: A Novel Approach for Acute Massive Hemorrhage Control in Dynamic and High ‐Pressure Wound Environments
This study presents a self-gelling powder comprising Na2HPO4 as the “H+ sucker ” withε-PLL and 4-arm-PEG-NHS as the hydrogel skeleton. Na2HPO4/ε-PLL/PEG demonstrates ultrafast self-gelation and robust wet adhesion. Applied to the dynamic and high-pressure wounds, the powder rapidly absorbs interfacial blood and undergoes an ultrafast powder-hydrogel transition that creates robust physical sealing while aggregating blood cells to accelerate coagulation. AbstractThe quest for efficient hemostatic agents in emergency medicine is critical, particularly for managing massive hemorrhages in dynamic and high-pressure wound e...
Source: Small - April 21, 2024 Category: Nanotechnology Authors: Kangli Chen, Kun Wang, Yanjun Pan, Yi Zhang, Jiajun Zhang, Shizhao Ji, Meng Yin, Changsheng Liu, Xue Qu Tags: Research Article Source Type: research

Engineering pH-sensitive dissolution of lipid-polymer nanoparticles by Eudragit integration impacts plasmid DNA (pDNA) transfection
In this study, biocompatible Eudragit constructs E100 and RS100 were formulated as lipid-polymer nanoparticles loaded with pDNA expressing red fluorescent protein (RFP) as a model therapeutic. Using a facile nanoprecipitation technique, a core-shell structure stabilised by lipid-polyethylene glycol (PEG) surfactant was produced and displayed resistance to ultracentrifugation. Both cationic polymers E100 (pH-sensitive dissolution at 5) and RS100 (pH-insensitive dissolution) produced 150-200 nm sized particles with a small positive surface charge (+3-5 mV) and high pDNA encapsulation efficiencies (EE) of 75-90 %. The dissolu...
Source: European Journal of Pharmaceutics and Biopharmaceutics - April 21, 2024 Category: Drugs & Pharmacology Authors: Diviya Santhanes Huiming Zhang Alex Wilkins Robert John Aitken Anne-Louise Gannon Mingtao Liang Source Type: research

Cutaneous adverse reactions associated with COVID-19 vaccines: Current evidence and potential immune mechanisms
Clin Immunol. 2024 Apr 18:110220. doi: 10.1016/j.clim.2024.110220. Online ahead of print.ABSTRACTAs the number of vaccinated individuals has increased, there have been increasing reports of cutaneous hypersensitivity reactions. The main COVID-19 vaccines administered include messenger ribonucleic acid vaccines, non-replicating viral vector vaccines, inactivated whole-virus vaccines, and protein-based vaccines. These vaccines contain active components such as polyethylene glycol, polysorbate 80, aluminum, tromethamine, and disodium edetate dihydrate. Recent advances in understanding the coordination of inflammatory response...
Source: Clinical Immunology - April 20, 2024 Category: Allergy & Immunology Authors: Po-Chien Wu Wan-Chen Lin Chuang-Wei Wang Wen-Hung Chung Chun-Bing Chen Source Type: research

Unusually large microporous HKUST-1 via polyethylene glycol-templated synthesis: enhanced CO 2 uptake with high selectivity over CH 4 and N 2 
Environ Sci Pollut Res Int. 2024 Apr 17. doi: 10.1007/s11356-024-33263-4. Online ahead of print.ABSTRACTPorous solids with highly microporous structures for effective carbon dioxide uptake and separation from mixed gases are highly desirable. Here we present the use of polyethylene glycol (20,000 g/mol) as a soft template for the simple and rapid synthesis of a highly microporous Cu-BTC (denoted as HKUST-1). The polyethylene glycol-templated HKUST-1 obtained at room temperature in 10 min exhibited a very high Brunauer-Emmett-Teller (BET) surface area of 1904 m2/g, pore volume of 0.87 cm3/g, and average micropore size of 0....
Source: Environmental Science and Pollution Research International - April 17, 2024 Category: Environmental Health Authors: Fahed A Aloufi Nadhem Missaoui Riyadh F Halawani Hamza Kahri Bassem Jamoussi Andrew J Gross Source Type: research

Metagenomic investigations into the microbial consortia, degradation pathways, and enzyme systems involved in the biodegradation of plastics in a tropical lentic pond sediment
AbstractThe exploitation of exciting features of plastics for diverse applications has resulted in significant plastic waste generation, which negatively impacts environmental compartments, metabolic processes, and the well-being of aquatic ecosystems biota. A shotgun metagenomic approach was deployed to investigate the microbial consortia, degradation pathways, and enzyme systems involved in the degradation of plastics in a tropical lentic pond sediment (APS). Functional annotation of the APS proteome (ORFs) using the PlasticDB database revealed annotation of 1015 proteins of enzymes such as depolymerase, esterase, lipase...
Source: World Journal of Microbiology and Biotechnology - April 17, 2024 Category: Microbiology Source Type: research

Polyvinyl alcohol/chitosan quaternary ammonium salt composite hydrogel with directional macroporous structure for photothermal synergistic antibacterial and wound healing promotion
Int J Biol Macromol. 2024 Apr 14:131549. doi: 10.1016/j.ijbiomac.2024.131549. Online ahead of print.ABSTRACTAfter skin tissue trauma, wound infections caused by bacteria posed a great threat to skin repair. However, resistance to antibiotics, the current treatment of choice for bacterial infections, greatly affected the efficiency of anti-infection and wound healing. Therefore, there has been a critical need for the development of novel antimicrobial materials and advanced therapeutic methods to aid in skin repair. In this paper, rGO-PDA@ZIF-8 nanofillers were prepared by coating graphene oxide (GO) with dopamine (DA), fol...
Source: International Journal of Biological Macromolecules - April 16, 2024 Category: Biochemistry Authors: Xianyu Lan Hang Yang Yuzhu Xiong Guanyue Zeng Fuping Dong Source Type: research

Design, optimization and pharmaceutical characterization of wound healing film dressings with chloramphenicol and ibuprofen
CONCLUSIONS: The QbD approach was successfully implemented to develop and optimize a novel film dressing promising for the treatment of low-exuding acute wounds prone to infection and inflammation.PMID:38622817 | DOI:10.1080/03639045.2024.2339306 (Source: Drug Development and Industrial Pharmacy)
Source: Drug Development and Industrial Pharmacy - April 16, 2024 Category: Drugs & Pharmacology Authors: Ioana Savencu Sonia Iurian C ătălina Bogdan Nicoleta Sp înu Maria Suciu Anca Pop Alexandru Țoc Ioan Tomu ță Source Type: research