A nanoporous gold film sensor modified with polypyrrole/CuO nanocomposite for electrochemical determination of piroxicam and tramadole
Environ Res. 2022 Nov 4:114633. doi: 10.1016/j.envres.2022.114633. Online ahead of print.ABSTRACTIn this paper, an electrochemical sensor was developed to determine piroxicam (PX) and tramadole (Tr) based on their enhanced electrochemical responses at the surface of the polypyrrole/CuO nanocomposite-modified nanoporous gold film (NPGF) electrode. The experimental results showed that PX provide an oxidation peak at 0.65 V in pH = 8.0. The DPV results were linearly affiliated on PX concentration within the two closed windows (C1PX = 0.05-30.0 μM, correlation coefficient of 0.9905, and C2PX = 50.0-300.0 μM, correlation coef...
Source: Environmental Research - November 7, 2022 Category: Environmental Health Authors: Mehrnoosh Sadeghi Mehdi Shabani-Nooshabadi Hanieh Ansarinejad Source Type: research

[ASAP] Pharmaceutical Salts of Piroxicam and Meloxicam with Organic Counterions
Crystal Growth& DesignDOI: 10.1021/acs.cgd.2c00722 (Source: Crystal Growth and Design)
Source: Crystal Growth and Design - October 21, 2022 Category: Chemistry Authors: Shan Huang, Dean S. Venables, and Simon E. Lawrence Source Type: research

Effectiveness of new selenium-enriched mutated probiotics in reducing inflammatory effects of piroxicam medication in liver and kidney
This study used selenium-enriched probiotics to reduce the side effects of piroxicam on the liver and kidney tissues and functions. Forty-eight male albino mice were randomly assigned to control, piroxicam (P), piroxicam plus selenium-enrichedLactobacillus plantarum PSe40/60/1  (P + SP), piroxicam plus selenium-enrichedBifidobacterium longum BSe50/20/1 (P  + SB), selenium-enrichedL. plantarum PSe40/60/1 (SP), and selenium-enrichedB. longum BSe50/20/1 (SB) groups. In this study, the function of the liver and kidney was biochemically determined; the histopathology of the liver and kidney tissues was microscopically ...
Source: Inflammopharmacology - September 9, 2022 Category: Drugs & Pharmacology Source Type: research

Fabrication of a novel sensor based on Cu quantum dot and SH-SiO < sub > 2 < /sub > nanoparticles supported on copper-based metal organic framework (Cu QD-SH-SiO < sub > 2 < /sub > @Cu-MOF) and its application for the simultaneous determination of norepinephrine, piroxicam and epinephrine
Talanta. 2022 Aug 8;252:123776. doi: 10.1016/j.talanta.2022.123776. Online ahead of print.ABSTRACTIn this research, a novel electrochemical sensor with excellent sensitivity was fabricated based on Cu quantum dot (Cu QD) and SH-SiO2 nanoparticles immobilized on copper-metal-organic frameworks (Cu-MOFs) for determining piroxicam and simultaneous determination of norepinephrine, piroxicam and epinephrine. The nanoparticles were synthesized and characterized using FT-IR, EDX, FESEM, TEM and BET, and were subsequently used to modify carbon paste electrode. Cu QD-SH-SiO2@Cu-MOF for electrode modification possesses a distinctive...
Source: Talanta - August 20, 2022 Category: Chemistry Authors: Fatemeh Fallah M Reza Shishehbore Ali Sheibani Source Type: research

Alloimperatorin from Ammi majus fruits mitigates Piroxicam-provoked gastric ulcer and hepatorenal toxicity in rats < em > via < /em > suppressing oxidative stress and apoptosis
Conclusion: Alloimperatorin exhibited anti-oxidative, anti-inflammatory, and anti-apoptotic activities.PMID:35837760 | DOI:10.1080/1354750X.2022.2102213 (Source: Biomarkers)
Source: Biomarkers - July 15, 2022 Category: Research Authors: Howaida I Abd-Alla Ghadha Ibrahim Fouad Kawkab A Ahmed Kamel Shaker Source Type: research

Alloimperatorin from Ammi majus fruits mitigates Piroxicam-provoked gastric ulcer and hepatorenal toxicity in rats < em > via < /em > suppressing oxidative stress and apoptosis
CONCLUSION: Alloimperatorin exhibited anti-oxidative, anti-inflammatory, and anti-apoptotic activities.PMID:35837760 | DOI:10.1080/1354750X.2022.2102213 (Source: Biomarkers)
Source: Biomarkers - July 15, 2022 Category: Research Authors: Howaida I Abd-Alla Ghadha Ibrahim Fouad Kawkab A Ahmed Kamel Shaker Source Type: research

Organic extract of < em > Geodia cydonium < /em > induces cell cycle block in human mesothelioma cells
In conclusion, to the best of our knowledge, the present results indicated for the first time that GEOCYDO can contain active compounds able to affect cell proliferation in mesothelioma, suggesting that it could be considered as a potential novel drug source for cancer treatment.PMID:35814825 | PMC:PMC9260718 | DOI:10.3892/ol.2022.13406 (Source: Oncology Letters)
Source: Oncology Letters - July 11, 2022 Category: Cancer & Oncology Authors: Francesco Di Meo Roberta Esposito Rossana Cuciniello Gregorio Favale Mario Arenga Nadia Ruocco Genoveffa Nuzzo Angelo Fontana Stefania Filosa Stefania Crispi Maria Costantini Source Type: research