Longitudinal cerebral perfusion in presymptomatic genetic frontotemporal dementia: GENFI results
DISCUSSION: Cerebral perfusion is a potential biomarker for assessing genetic FTD and its genetic subgroups prior to symptom onset.HIGHLIGHTS: Gray matter perfusion declines in at-risk genetic frontotemporal dementia (FTD). Regional perfusion decline differs between at-risk genetic FTD subgroups . Hypoperfusion in the left thalamus is common across all presymptomatic groups. Converters exhibit greater right frontal hypoperfusion than non-converters past their expected conversion date. Cerebral hypoperfusion is a potential early biomarker of genetic FTD.PMID:38623902 | DOI:10.1002/alz.13750 (Source: The Journal of Alzheimers Association)
Source: The Journal of Alzheimers Association - April 16, 2024 Category: Psychiatry Authors: Maurice Pasternak Saira S Mirza Nicholas Luciw Henri J M M Mutsaerts Jan Petr David Thomas David Cash Martina Bocchetta Maria Carmela Tartaglia Sara B Mitchell Sandra E Black Morris Freedman David Tang-Wai Ekaterina Rogaeva Lucy L Russell Arabella Bouzigu Source Type: research
SPINNED: Simulation-based physics-informed neural network for deconvolution of dynamic susceptibility contrast MRI perfusion data
CONCLUSION: These results support that the proposed SPINNED method can be a good alternative to the existing methods for resolving the deconvolution problem in DSC MRI. The proposed method does not require any separate ground-truth measurement for training and offers additional benefits of quick processing time and coverage of diverse clinical scenarios. Consequently, it will contribute to more reliable, accurate, and rapid diagnoses in clinical applications compared with the previous methods including those based on supervised learning.PMID:38623911 | DOI:10.1002/mrm.30095 (Source: Magnetic Resonance in Medicine)
Source: Magnetic Resonance in Medicine - April 16, 2024 Category: Radiology Authors: Muhammad Asaduddin Eung Yeop Kim Sung-Hong Park Source Type: research
Uterine infusion strategies for infertile patients with recurrent implantation failure: a systematic review and network meta-analysis
CONCLUSIONS: Intrauterine infusion of HCG, PBMC, G-CSF, and PRP are promising strategies for improving pregnancy outcomes for infertile patients with recurrent implantation failure. Among these treatments, PRP may be the best. More researches are required to explore the effect of drug combinations and less commonly used drugs as well.TRIAL REGISTRATION: Our study was registered in PROSPERO and the ID was CRD42023467188.PMID:38627790 | DOI:10.1186/s12958-024-01221-x (Source: Reproductive Biology)
Source: Reproductive Biology - April 16, 2024 Category: Reproduction Medicine Authors: Qin Xie Xiaozhen Quan Yanli Lan Xuezhou Yang Source Type: research
Clinical outcomes in critically ill children on extracorporeal membrane oxygenation with severe thrombocytopenia
CONCLUSIONS: Our results indicate a restrictive platelet transfusion strategy is not associated with higher proportions of subsequent bleeding, duration of ECMO, or on-ECMO mortality rate. Multicenter studies are needed to evaluate further the appropriateness of this strategy.PMID:38626382 | DOI:10.1177/02676591241247981 (Source: Perfusion)
Source: Perfusion - April 16, 2024 Category: Cardiovascular & Thoracic Surgery Authors: Sonia Labarinas Kalpana Norbisrath Dana Johnson Jon Meliones Christopher Greenleaf Jorge Salazar Oliver Karam Source Type: research
Perioperative management of a double valve replacement and coronary artery bypass graft in a patient with carcinoid syndrome; a case report and literature review
CONCLUSION: No carcinoid crisis was evident perioperatively. High vigilance with appropriate monitoring, aggressive management combined with meticulous choice of pharmaceutical agents led to this outcome.PMID:38626318 | DOI:10.1177/02676591241247977 (Source: Perfusion)
Source: Perfusion - April 16, 2024 Category: Cardiovascular & Thoracic Surgery Authors: Despoina G Sarridou Anna Gkiouliava Helena Argiriadou Sophia Anastasia Mouratoglou Jeremy B Mitchell Christopher P Walker Source Type: research
Correction to 'corrigendum to "Microplegia in paediatric hearts"'
Perfusion. 2024 Apr 15:2676591241240299. doi: 10.1177/02676591241240299. Online ahead of print.NO ABSTRACTPMID:38622967 | DOI:10.1177/02676591241240299 (Source: Perfusion)
Source: Perfusion - April 16, 2024 Category: Cardiovascular & Thoracic Surgery Source Type: research
Prediction of postoperative cerebral infarction after combined bypass surgery in adult moyamoya disease: combining quantitative parameters on RAPID perfusion CT with clinically related factors
CONCLUSIONS: For adult patients with MMD and a large volume of Tmax > 6 sec over 59.5 ml, more caution is required when deciding to undergo bypass surgery and in postoperative management.PMID:38626473 | DOI:10.3171/2024.1.JNS232641 (Source: Journal of Neurosurgery)
Source: Journal of Neurosurgery - April 16, 2024 Category: Neurosurgery Authors: Si Un Lee Yongjae Lee Tae Won Choi Sang Hyo Lee Young-Deok Kim Seung Pil Ban O-Ki Kwon Chang Wan Oh Jae Seung Bang Source Type: research
Longitudinal cerebral perfusion in presymptomatic genetic frontotemporal dementia: GENFI results
DISCUSSION: Cerebral perfusion is a potential biomarker for assessing genetic FTD and its genetic subgroups prior to symptom onset.HIGHLIGHTS: Gray matter perfusion declines in at-risk genetic frontotemporal dementia (FTD). Regional perfusion decline differs between at-risk genetic FTD subgroups . Hypoperfusion in the left thalamus is common across all presymptomatic groups. Converters exhibit greater right frontal hypoperfusion than non-converters past their expected conversion date. Cerebral hypoperfusion is a potential early biomarker of genetic FTD.PMID:38623902 | DOI:10.1002/alz.13750 (Source: The Journal of Alzheimers Association)
Source: The Journal of Alzheimers Association - April 16, 2024 Category: Psychiatry Authors: Maurice Pasternak Saira S Mirza Nicholas Luciw Henri J M M Mutsaerts Jan Petr David Thomas David Cash Martina Bocchetta Maria Carmela Tartaglia Sara B Mitchell Sandra E Black Morris Freedman David Tang-Wai Ekaterina Rogaeva Lucy L Russell Arabella Bouzigu Source Type: research
SPINNED: Simulation-based physics-informed neural network for deconvolution of dynamic susceptibility contrast MRI perfusion data
CONCLUSION: These results support that the proposed SPINNED method can be a good alternative to the existing methods for resolving the deconvolution problem in DSC MRI. The proposed method does not require any separate ground-truth measurement for training and offers additional benefits of quick processing time and coverage of diverse clinical scenarios. Consequently, it will contribute to more reliable, accurate, and rapid diagnoses in clinical applications compared with the previous methods including those based on supervised learning.PMID:38623911 | DOI:10.1002/mrm.30095 (Source: Magnetic Resonance in Medicine)
Source: Magnetic Resonance in Medicine - April 16, 2024 Category: Radiology Authors: Muhammad Asaduddin Eung Yeop Kim Sung-Hong Park Source Type: research
Prediction of postoperative cerebral infarction after combined bypass surgery in adult moyamoya disease: combining quantitative parameters on RAPID perfusion CT with clinically related factors
CONCLUSIONS: For adult patients with MMD and a large volume of Tmax > 6 sec over 59.5 ml, more caution is required when deciding to undergo bypass surgery and in postoperative management.PMID:38626473 | DOI:10.3171/2024.1.JNS232641 (Source: Journal of Neurosurgery)
Source: Journal of Neurosurgery - April 16, 2024 Category: Neurosurgery Authors: Si Un Lee Yongjae Lee Tae Won Choi Sang Hyo Lee Young-Deok Kim Seung Pil Ban O-Ki Kwon Chang Wan Oh Jae Seung Bang Source Type: research
SPINNED: Simulation-based physics-informed neural network for deconvolution of dynamic susceptibility contrast MRI perfusion data
CONCLUSION: These results support that the proposed SPINNED method can be a good alternative to the existing methods for resolving the deconvolution problem in DSC MRI. The proposed method does not require any separate ground-truth measurement for training and offers additional benefits of quick processing time and coverage of diverse clinical scenarios. Consequently, it will contribute to more reliable, accurate, and rapid diagnoses in clinical applications compared with the previous methods including those based on supervised learning.PMID:38623911 | DOI:10.1002/mrm.30095 (Source: Magnetic Resonance in Medicine)
Source: Magnetic Resonance in Medicine - April 16, 2024 Category: Radiology Authors: Muhammad Asaduddin Eung Yeop Kim Sung-Hong Park Source Type: research
Prediction of postoperative cerebral infarction after combined bypass surgery in adult moyamoya disease: combining quantitative parameters on RAPID perfusion CT with clinically related factors
CONCLUSIONS: For adult patients with MMD and a large volume of Tmax > 6 sec over 59.5 ml, more caution is required when deciding to undergo bypass surgery and in postoperative management.PMID:38626473 | DOI:10.3171/2024.1.JNS232641 (Source: Journal of Neurosurgery)
Source: Journal of Neurosurgery - April 16, 2024 Category: Neurosurgery Authors: Si Un Lee Yongjae Lee Tae Won Choi Sang Hyo Lee Young-Deok Kim Seung Pil Ban O-Ki Kwon Chang Wan Oh Jae Seung Bang Source Type: research
Prediction of postoperative cerebral infarction after combined bypass surgery in adult moyamoya disease: combining quantitative parameters on RAPID perfusion CT with clinically related factors
CONCLUSIONS: For adult patients with MMD and a large volume of Tmax > 6 sec over 59.5 ml, more caution is required when deciding to undergo bypass surgery and in postoperative management.PMID:38626473 | DOI:10.3171/2024.1.JNS232641 (Source: Journal of Neurosurgery)
Source: Journal of Neurosurgery - April 16, 2024 Category: Neurosurgery Authors: Si Un Lee Yongjae Lee Tae Won Choi Sang Hyo Lee Young-Deok Kim Seung Pil Ban O-Ki Kwon Chang Wan Oh Jae Seung Bang Source Type: research
Isolated Fragments of Intact Microvessels: Tissue Vascularization, Modeling, and Therapeutics
ABSTRACTThe microvasculature is integral to nearly every tissue in the body, providing not only perfusion to and from the tissue, but also homing sites for immune cells, cellular niches for tissue dynamics, and cooperative interactions with other tissue elements. As a microtissue itself, the microvasculature is a composite of multiple cell types exquisitely organized into structures (individual vessel segments and extensive vessel networks) capable of considerable dynamics and plasticity. Consequently, it has been challenging to include a functional microvasculature in assembled or fabricated tissues. Isolated fragments of...
Source: Microcirculation - April 16, 2024 Category: Research Authors: Hannah A. Strobel,
Sarah M. Moss,
James B. Hoying Tags: REVIEW Source Type: research
Post-ductal coarctation of aorta aneurysm repair in adult via left antero-axillary thoracotomy with antegrade cerebral perfusion —a case series
We describe our experience in managing three such patients through antero-lateral thoracotomy with antegrade cerebral perfusion. We have found this technique helpful in treating aneurysms of the distal aortic arch or proximal descending thoracic aorta. (Source: Indian Journal of Thoracic and Cardiovascular Surgery)
Source: Indian Journal of Thoracic and Cardiovascular Surgery - April 16, 2024 Category: Cardiovascular & Thoracic Surgery Source Type: research
