PDA Occlusion Using NIRS
Conditions: Organ Perfusion Determined by Using NIRS Post Transcatheter PDA Occlusion or Medical Closure of PDA Interventions: Device: NIRS monitor Sponsors: University of Louisville; Norton Healthcare Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - April 11, 2024 Category: Research Source Type: clinical trials

Assessing Repeatability and Intra-individual Variability in [O15]H2O-PET Myocardial Perfusion Imaging
Conditions: Myocardial Blood Flow Interventions: Diagnostic Test: Myocardial perfusion imaging (MPI) using [O15]H2O-PET-CT Sponsors: Peter Hovind Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - April 10, 2024 Category: Research Source Type: clinical trials

Hemodynamic Effects of Steep Trendelenburg Position and Pneumoperitoneum
Conditions: Perfusion Index; Pleth Variability Index Sponsors: Ege University Completed (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - April 8, 2024 Category: Research Source Type: clinical trials

NRM on Vascular Perfusion in Heathy Adults
Conditions: Vascular Stiffness Interventions: Dietary Supplement: Nicotinamide Riboside Malate; Other: Placebo Sponsors: Mayo Clinic Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - April 3, 2024 Category: Research Source Type: clinical trials

Computational mOdelliNg of myoCardial pERfusion to Improve ouTcome Prediction Based on cOronary Artery Stenosis and Atherosclerotic Plaque Burden Assessment by Computed Tomography
Conditions: Chronic Coronary Syndrome Sponsors: Centro Cardiologico Monzino; Azienda Ospedaliero-Universitaria Consorziale Policlinico di Bari; Politecnico di Milano Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - March 29, 2024 Category: Research Source Type: clinical trials

Mechanisms of Pulmonary Vascular Dysfunction in Heart Failure
Conditions: Heart Failure; Pulmonary Hypertension; Pulmonary Vascular Resistance Abnormality Interventions: Diagnostic Test: non-contrast chest CT; Diagnostic Test: spirometry with diffusing lung capacity for carbon monoxide (DLCO) analysis; Diagnostic Test: Omics analysis of blood plasma obtained from pulmonary artery or peripheral blood; Diagnostic Test: supine bike exercise during right heart catheterisation; Diagnostic Test: Lung ventilation/perfusion SPECT Sponsors: Institute for Clinical and Experimental Medicine Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - March 26, 2024 Category: Research Source Type: clinical trials

Optimization of cardiopulmonary bypass prime fluid to preserve microcirculatory perfusion during on-pump coronary artery bypass graft surgery: PRIME study protocol for a double-blind randomized trial
DiscussionPRIME is the first study to assess the effect of different prime fluid strategies on microcirculatory perfusion in cardiac surgery with CPB. If the results suggest that a specific crystalloid or colloid prime fluid strategy better preserves microcirculatory perfusion during on-pump cardiac surgery, the current study may help to find the optimal pump priming in cardiac surgery.Trial registrationClinicalTrials.gov NCT05647057. Registered on 04/25/2023. ClinicalTrials.gov PRS: Record Summary NCT05647057, all items can be found in the protocol. (Source: Trials)
Source: Trials - March 26, 2024 Category: Research Source Type: clinical trials

Intraoperative Intestinal Perfusion Assessment by Fluorescence Angiography in Emergency Surgery
Conditions: Bowel; Ischemic, Acute Interventions: Other: Indocyanine green Sponsors: Rigshospitalet, Denmark Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - March 21, 2024 Category: Research Source Type: clinical trials

Comparison of Free-breathing 3D Quantitative Perfusion in Patients With MINOCA and MINOCA-mimics
Conditions: Myocardial Infarction With Non-Obstructive Coronary Artery; Myocarditis Acute; Takotsubo Cardiomyopathy; Spontaneous Coronary Artery Dissection; Non ST Elevation Myocardial Infarction Interventions: Diagnostic Test: CMR Sponsors: University of Zurich; ETH Zurich Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - March 21, 2024 Category: Research Source Type: clinical trials

Intestinal Perfusion After Feeding in Preterm and Term Infants
Conditions: Premature; Necrotizing Enterocolitis Interventions: Other: Evaluation of intestinal perfusion with color Doppler abdominal ultrasound before and after feeding. Sponsors: The Hospital for Sick Children; Xiamen Children ' s Hospital Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - March 20, 2024 Category: Research Source Type: clinical trials

Improvements in Dynamic Contrast-Enhanced MR Angiography and Perfusion
Conditions: Prostate Neoplasm Interventions: Other: Non-Interventional Study Sponsors: Mayo Clinic; National Cancer Institute (NCI); National Institute for Biomedical Imaging and Bioengineering (NIBIB) Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - March 18, 2024 Category: Research Source Type: clinical trials

CMR Assessment of Cardiac Microvascular Dysfunction in Patients With HFpEF
Conditions: Microvascular Coronary Artery Disease; Heart Failure With Reduced Ejection Fraction Interventions: Diagnostic Test: stress perfusion cardiac magnetic resonance; Diagnostic Test: cardiopulmonary exercise test Sponsors: Istituto Auxologico Italiano Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - March 18, 2024 Category: Research Source Type: clinical trials

Beyond MARS: Magnetic Resonance Study: A Novel Assessment of Placental Perfusion During Pregnancy
Conditions: Placenta Diseases Interventions: Diagnostic Test: functional Magnetic Resonance Imaging (fMRI) Sponsors: NorthShore University HealthSystem Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - March 15, 2024 Category: Research Source Type: clinical trials

Plethysmographic Perfusion Index and Fluid Responsiveness
Conditions: Fluid Responsiveness Interventions: Diagnostic Test: Perfusion index Sponsors: Avicenna Military Hospital Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - March 15, 2024 Category: Research Source Type: clinical trials

Mean Arterial Pressure (MAP) Trial: study protocol for a multicentre, randomized, controlled trial to compare three different strategies of mean arterial pressure management during cardiopulmonary bypass
We described herein the methodology of a multicentre, randomized, controlled trial comparing three different approaches to MAP management during CPB in patients undergoing elective cardiac surgery: the historically accepted “standard MAP” (50–60 mmHg), the “high MAP” (70–80 mmHg) and the “patient-tailored MAP” (comparable to the patient’s preoperative MAP). It is the aim of the study to find the most suitable management in order to obtain the most adequate perfusion of end-organs during cardiac surger y. For this purpose, the primary endpoint will be the peak of serum lactate (Lmax) released during CPB, a...
Source: Trials - March 15, 2024 Category: Research Source Type: clinical trials