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Comparison of intravesical chemotherapy regimens after radical nephroureterectomy for upper tract urothelial carcinoma and analysis of risk factors for postoperative recurrence
CONCLUSIONS: Epirubicin and gemcitabine reduced the occurrence of bladder cancer and effectively inhibited tumor angiogenesis after radical nephroureterectomy for UTUC. The tumor location, number of lesions, tumor stage, preoperative ureteral examination, and preoperative history of bladder cancer were risk factors for postoperative bladder cancer.PMID:38567601 | DOI:10.26355/eurrev_202403_35745 (Source: European Review for Medical and Pharmacological Sciences)
Source: European Review for Medical and Pharmacological Sciences - April 3, 2024 Category: Drugs & Pharmacology Authors: S-C Jiang Y-G Liao J Luo D Hu Y-D Wang K He Source Type: research

Globalization of perfusion education: Our profession's contribution to addressing cardiac surgery inequity worldwide
Perfusion. 2024 Apr 3:2676591241242636. doi: 10.1177/02676591241242636. Online ahead of print.NO ABSTRACTPMID:38569138 | DOI:10.1177/02676591241242636 (Source: Perfusion)
Source: Perfusion - April 3, 2024 Category: Cardiovascular & Thoracic Surgery Authors: Bruce Searles Robert Groom Source Type: research

Donation After Circulatory Death Heart Transplantation: A Narrative Review
Heart transplantation is the definitive treatment for refractory, end-stage heart failure. The number of patients awaiting transplantation far exceeds available organs. In an effort to expand the donor pool, donation after circulatory death (DCD) heart transplantation has garnered renewed interest. Unlike, donation after brain death, DCD donors do not meet criteria for brain death and are dependent on life-sustaining therapies. Procurement can include a direct strategy or normothermic regional perfusion, whereby there is restoration of perfusion to the organ prior to explantation. (Source: Journal of Cardiothoracic and Vascular Anesthesia)
Source: Journal of Cardiothoracic and Vascular Anesthesia - April 3, 2024 Category: Anesthesiology Authors: Dr. Kristin Constantine Trela, Dr. Christopher T. Salerno, Dr. Emuejevoke Chuba, Dr. Richa Dhawan Tags: Review Article Source Type: research

Convolutional Neural Networks To Study Contrast-Enhanced Magnetic Resonance Imaging Based Skeletal Calf Muscle Perfusion In Peripheral Artery Disease
Peripheral artery disease (PAD) is associated with impaired blood flow in the lower extremities and histopathological changes of the skeletal calf muscles resulting in abnormal microvascular perfusion. We studied the use of convolutional neural networks (CNNs) to differentiate PAD patients from matched controls by utilizing perfusion pattern features from contrast-enhanced magnetic resonance imaging (CE-MRI) of the skeletal calf muscles. We acquired CE-MRI based skeletal calf muscle perfusion in 56 individuals (36 PAD patients, 20 matched controls). (Source: The American Journal of Cardiology)
Source: The American Journal of Cardiology - April 3, 2024 Category: Cardiology Authors: Bijen Khagi, Tatiana Belousova, Christina M. Short, Addison Taylor, Jean Bismuth, Dipan J. Shah, Gerd Brunner Source Type: research

Development of a protocol for standardized use of a water-soluble contrast agent with polyethylene glycol in post-mortem CT angiography
AbstractComputed tomography angiography (PMCTA) is increasingly used in postmortem cases. Standardized validated protocols permit to compare different PMCTA images and make it more easily to defend a case in court. In addition to the well-known technique by Grabherr et al. (2011) which is using paraffin oil as a carrier substance, water-soluble polyethylene glycol 200 (PEG200) can be used in combination with the contrast agent Accupaque ® 300. As to date, there exists no standardized protocol for the use of this contrast agent mixture, the aim of this study was to develop a protocol using it. Between 2012 and 2022, 23 PMC...
Source: International Journal of Legal Medicine - April 3, 2024 Category: Medical Law Source Type: research

Normothermic Regional Perfusion to Expand Liver Transplant From cDCD
Controlled donation after circulatory death (cDCD) donors, who are declared dead following cardiorespiratory arrest, are a growing source of organs. DCD is the best field for donor expansion to help to alleviate the organ shortage. Already in 2009, the American Society of Transplant Surgeons recommended focusing efforts on increasing the number of organs from cDCD. However, in the US, only 11.4% of liver recipients who undergo transplant from a deceased donor receive a cDCD liver. Other sources of donor expansion, such as living donors, account for less than 10% of liver donation in US and even less in Europe. (Source: JAMA Surgery)
Source: JAMA Surgery - April 3, 2024 Category: Sports Medicine Source Type: research

US Liver Transplant Outcomes After Normothermic Regional Perfusion vs Standard Super Rapid Recovery
This cohort study investigates the outcomes of US liver transplants using controlled donation after circulatory death livers recovered with normothermic regional perfusion vs standard super rapid recovery. (Source: JAMA Surgery)
Source: JAMA Surgery - April 3, 2024 Category: Sports Medicine Source Type: research