Image denoising and model-independent parameterization for IVIM MRI
Phys Med Biol. 2024 Apr 11. doi: 10.1088/1361-6560/ad3db8. Online ahead of print.ABSTRACTObjective: To improve intravoxel incoherent motion imaging (IVIM) magnetic resonance Imaging (MRI) quality using a new image denoising technique and model-independent parameterization of the signal versus b-value curve.Approach: IVIM images were acquired for 13 head-and-neck patients prior to radiotherapy. Post-radiotherapy scans were also acquired for five patients. Images were denoised prior to parameter fitting using neural blind deconvolution, a method of solving the mathematical problem of blind deconvolution using neural networks...
Source: Physics in Medicine and Biology - April 11, 2024 Category: Physics Authors: Caleb Sample Jonn Wu Haley Clark Source Type: research
Synergistic large segmental bone repair by 3D printed bionic scaffolds and engineered ADSC nanovesicles: Towards an optimized regenerative microenvironment
This study utilized digital laser processing (DLP)-based 3D printing technology to successfully fabricate high-precision methacryloylated polycaprolactone (PCLMA) bionic bone scaffold structures. Adipose-derived stem cell-engineered nanovesicles (ADSC-ENs) were uniformly and stably modified onto the bionic scaffold surface using a perfusion device, constructing a conducive microenvironment for tissue regeneration and long bone defect repair through the scaffold's structural design and the vesicles' biological functions. Scanning electron microscopy (SEM) examination of the scaffold surface confirmed the efficient loading o...
Source: Biomaterials - April 11, 2024 Category: Materials Science Authors: Wenbin Jiang Yichen Zhan Yifan Zhang Di Sun Guo Zhang Zhenxing Wang Lifeng Chen Jiaming Sun Source Type: research
Image denoising and model-independent parameterization for IVIM MRI
Phys Med Biol. 2024 Apr 11. doi: 10.1088/1361-6560/ad3db8. Online ahead of print.ABSTRACTObjective: To improve intravoxel incoherent motion imaging (IVIM) magnetic resonance Imaging (MRI) quality using a new image denoising technique and model-independent parameterization of the signal versus b-value curve.Approach: IVIM images were acquired for 13 head-and-neck patients prior to radiotherapy. Post-radiotherapy scans were also acquired for five patients. Images were denoised prior to parameter fitting using neural blind deconvolution, a method of solving the mathematical problem of blind deconvolution using neural networks...
Source: Physics in Medicine and Biology - April 11, 2024 Category: Physics Authors: Caleb Sample Jonn Wu Haley Clark Source Type: research
Synergistic large segmental bone repair by 3D printed bionic scaffolds and engineered ADSC nanovesicles: Towards an optimized regenerative microenvironment
This study utilized digital laser processing (DLP)-based 3D printing technology to successfully fabricate high-precision methacryloylated polycaprolactone (PCLMA) bionic bone scaffold structures. Adipose-derived stem cell-engineered nanovesicles (ADSC-ENs) were uniformly and stably modified onto the bionic scaffold surface using a perfusion device, constructing a conducive microenvironment for tissue regeneration and long bone defect repair through the scaffold's structural design and the vesicles' biological functions. Scanning electron microscopy (SEM) examination of the scaffold surface confirmed the efficient loading o...
Source: Biomaterials - April 11, 2024 Category: Materials Science Authors: Wenbin Jiang Yichen Zhan Yifan Zhang Di Sun Guo Zhang Zhenxing Wang Lifeng Chen Jiaming Sun Source Type: research
Recommendations for quantitative cerebral perfusion MRI using multi-timepoint arterial spin labeling: Acquisition, quantification, and clinical applications
This article is part of a series published by the International Society for Magnetic Resonance in Medicine (ISMRM) Perfusion Study Group, aiming to guide and inspire the advancement and utilization of ASL beyond the scope of the 2015 consensus article.PMID:38594906 | DOI:10.1002/mrm.30091 (Source: Magnetic Resonance in Medicine)
Source: Magnetic Resonance in Medicine - April 10, 2024 Category: Radiology Authors: Joseph G Woods Eric Achten Iris Asllani Divya S Bolar Weiying Dai John A Detre Audrey P Fan Mar ía A Fernández-Seara Xavier Golay Matthias G ünther Jia Guo Luis Hernandez-Garcia Mai-Lan Ho Meher R Juttukonda Hanzhang Lu Bradley J MacIntosh Ananth J Mad Source Type: research
Perioperative complications of minor and major reinterventions for peripheral arterial disease
CONCLUSIONS: In this study, major reinterventions after LER were associated with greater perioperative morbidity than minor reinterventions, with no difference in mortality. Major reinterventions performed via open surgery and CDT had similar morbidity and mortality.PMID:38597200 | DOI:10.1177/17085381241246907 (Source: Vascular)
Source: Vascular - April 10, 2024 Category: Surgery Authors: Joshua J Huttler Keyuree K Satam Tanner I Kim Haoran Zhuo Yawei Zhang Edouard Aboian Raul J Guzman Cassius Iyad Ochoa Chaar Source Type: research
Diagnostic and prognostic value of mannan-binding lectin associated protein (MAp19) for functionally relevant coronary artery disease
CONCLUSION: MAp19 demonstrated an association with the risk of myocardial infarction. Increases in MAp19 concentration were observed during bicycle and combined stress-tests.PMID:38599540 | DOI:10.1016/j.cca.2024.119668 (Source: International Journal of Clinical Chemistry)
Source: International Journal of Clinical Chemistry - April 10, 2024 Category: Chemistry Authors: Ganna Isayeva Klara Rumora Eliska Potlukova Jan-Philipp Leibfarth Ibrahim Sch äfer Zsofia Bartha Michael J Zellweger Marten Trendelenburg Trine Korsgaard Hejlesen Annette Gudmann Hansen Steffen Thiel Christian Mueller Source Type: research
Recommendations for quantitative cerebral perfusion MRI using multi-timepoint arterial spin labeling: Acquisition, quantification, and clinical applications
This article is part of a series published by the International Society for Magnetic Resonance in Medicine (ISMRM) Perfusion Study Group, aiming to guide and inspire the advancement and utilization of ASL beyond the scope of the 2015 consensus article.PMID:38594906 | DOI:10.1002/mrm.30091 (Source: Magnetic Resonance in Medicine)
Source: Magnetic Resonance in Medicine - April 10, 2024 Category: Radiology Authors: Joseph G Woods Eric Achten Iris Asllani Divya S Bolar Weiying Dai John A Detre Audrey P Fan Mar ía A Fernández-Seara Xavier Golay Matthias G ünther Jia Guo Luis Hernandez-Garcia Mai-Lan Ho Meher R Juttukonda Hanzhang Lu Bradley J MacIntosh Ananth J Mad Source Type: research
Perioperative complications of minor and major reinterventions for peripheral arterial disease
CONCLUSIONS: In this study, major reinterventions after LER were associated with greater perioperative morbidity than minor reinterventions, with no difference in mortality. Major reinterventions performed via open surgery and CDT had similar morbidity and mortality.PMID:38597200 | DOI:10.1177/17085381241246907 (Source: Vascular)
Source: Vascular - April 10, 2024 Category: Surgery Authors: Joshua J Huttler Keyuree K Satam Tanner I Kim Haoran Zhuo Yawei Zhang Edouard Aboian Raul J Guzman Cassius Iyad Ochoa Chaar Source Type: research
Diagnostic and prognostic value of mannan-binding lectin associated protein (MAp19) for functionally relevant coronary artery disease
CONCLUSION: MAp19 demonstrated an association with the risk of myocardial infarction. Increases in MAp19 concentration were observed during bicycle and combined stress-tests.PMID:38599540 | DOI:10.1016/j.cca.2024.119668 (Source: International Journal of Clinical Chemistry)
Source: International Journal of Clinical Chemistry - April 10, 2024 Category: Chemistry Authors: Ganna Isayeva Klara Rumora Eliska Potlukova Jan-Philipp Leibfarth Ibrahim Sch äfer Zsofia Bartha Michael J Zellweger Marten Trendelenburg Trine Korsgaard Hejlesen Annette Gudmann Hansen Steffen Thiel Christian Mueller Source Type: research
Recommendations for quantitative cerebral perfusion MRI using multi-timepoint arterial spin labeling: Acquisition, quantification, and clinical applications
This article is part of a series published by the International Society for Magnetic Resonance in Medicine (ISMRM) Perfusion Study Group, aiming to guide and inspire the advancement and utilization of ASL beyond the scope of the 2015 consensus article.PMID:38594906 | DOI:10.1002/mrm.30091 (Source: Magnetic Resonance in Medicine)
Source: Magnetic Resonance in Medicine - April 10, 2024 Category: Radiology Authors: Joseph G Woods Eric Achten Iris Asllani Divya S Bolar Weiying Dai John A Detre Audrey P Fan Mar ía A Fernández-Seara Xavier Golay Matthias G ünther Jia Guo Luis Hernandez-Garcia Mai-Lan Ho Meher R Juttukonda Hanzhang Lu Bradley J MacIntosh Ananth J Mad Source Type: research
Diagnostic and prognostic value of mannan-binding lectin associated protein (MAp19) for functionally relevant coronary artery disease
CONCLUSION: MAp19 demonstrated an association with the risk of myocardial infarction. Increases in MAp19 concentration were observed during bicycle and combined stress-tests.PMID:38599540 | DOI:10.1016/j.cca.2024.119668 (Source: International Journal of Clinical Chemistry)
Source: International Journal of Clinical Chemistry - April 10, 2024 Category: Chemistry Authors: Ganna Isayeva Klara Rumora Eliska Potlukova Jan-Philipp Leibfarth Ibrahim Sch äfer Zsofia Bartha Michael J Zellweger Marten Trendelenburg Trine Korsgaard Hejlesen Annette Gudmann Hansen Steffen Thiel Christian Mueller Source Type: research
Recommendations for quantitative cerebral perfusion MRI using multi-timepoint arterial spin labeling: Acquisition, quantification, and clinical applications
This article is part of a series published by the International Society for Magnetic Resonance in Medicine (ISMRM) Perfusion Study Group, aiming to guide and inspire the advancement and utilization of ASL beyond the scope of the 2015 consensus article.PMID:38594906 | DOI:10.1002/mrm.30091 (Source: Magnetic Resonance in Medicine)
Source: Magnetic Resonance in Medicine - April 10, 2024 Category: Radiology Authors: Joseph G Woods Eric Achten Iris Asllani Divya S Bolar Weiying Dai John A Detre Audrey P Fan Mar ía A Fernández-Seara Xavier Golay Matthias G ünther Jia Guo Luis Hernandez-Garcia Mai-Lan Ho Meher R Juttukonda Hanzhang Lu Bradley J MacIntosh Ananth J Mad Source Type: research
Unraveling the Gordian knot of coronary pressure-flow autoregulation
The coronary circulation has the inherent ability to maintain myocardial perfusion constant over a wide range of perfusion pressures. The phenomenon of pressure-flow autoregulation is crucial in response to flow-limiting atherosclerotic lesions which diminish coronary driving pressure and increase risk of myocardial ischemia and infarction. Despite well over half a century of devoted research, understanding of the mechanisms responsible for autoregulation remains one of the most fundamental and contested questions in the field today. (Source: Journal of Molecular and Cellular Cardiology)
Source: Journal of Molecular and Cellular Cardiology - April 10, 2024 Category: Cytology Authors: Johnathan D. Tune, Cooper M. Warne, Salman I. Essajee, Selina M. Tucker, C. Alberto Figueroa, Gregory M. Dick, Daniel A. Beard Tags: Review article Source Type: research
Inhibition of Notch3/Hey1 ameliorates peribiliary hypoxia by preventing hypertrophic hepatic arteriopathy in biliary atresia progression
This study examined both human and experimental BA. Structural and hemodynamic features of hepatic arteries were investigated by Doppler ultrasound, ind ocyanine green angiography, microscopic histology, and invasive arterial pressure measurement. Opal multiplex immunohistochemistry, western blot, and RT-PCR were applied to assess Notch3 expression and the phenotype of hepatic arterial smooth muscle cells (HASMCs). We established animal models of N otch3 inhibition, overexpression, and knockout to evaluate the differences in overall survival, hepatic artery morphology, peribiliary hypoxia, and HASMC phenotype. Hypertrophi...
Source: Histochemistry and Cell Biology - April 10, 2024 Category: Biomedical Science Source Type: research
