Prediction of postoperative cerebral infarction after combined bypass surgery in adult moyamoya disease: combining quantitative parameters on RAPID perfusion CT with clinically related factors
CONCLUSIONS: For adult patients with MMD and a large volume of Tmax > 6 sec over 59.5 ml, more caution is required when deciding to undergo bypass surgery and in postoperative management.PMID:38626473 | DOI:10.3171/2024.1.JNS232641 (Source: Journal of Neurosurgery)
Source: Journal of Neurosurgery - April 16, 2024 Category: Neurosurgery Authors: Si Un Lee Yongjae Lee Tae Won Choi Sang Hyo Lee Young-Deok Kim Seung Pil Ban O-Ki Kwon Chang Wan Oh Jae Seung Bang Source Type: research

Longitudinal cerebral perfusion in presymptomatic genetic frontotemporal dementia: GENFI results
DISCUSSION: Cerebral perfusion is a potential biomarker for assessing genetic FTD and its genetic subgroups prior to symptom onset.HIGHLIGHTS: Gray matter perfusion declines in at-risk genetic frontotemporal dementia (FTD). Regional perfusion decline differs between at-risk genetic FTD subgroups . Hypoperfusion in the left thalamus is common across all presymptomatic groups. Converters exhibit greater right frontal hypoperfusion than non-converters past their expected conversion date. Cerebral hypoperfusion is a potential early biomarker of genetic FTD.PMID:38623902 | DOI:10.1002/alz.13750 (Source: The Journal of Alzheimers Association)
Source: The Journal of Alzheimers Association - April 16, 2024 Category: Psychiatry Authors: Maurice Pasternak Saira S Mirza Nicholas Luciw Henri J M M Mutsaerts Jan Petr David Thomas David Cash Martina Bocchetta Maria Carmela Tartaglia Sara B Mitchell Sandra E Black Morris Freedman David Tang-Wai Ekaterina Rogaeva Lucy L Russell Arabella Bouzigu Source Type: research

SPINNED: Simulation-based physics-informed neural network for deconvolution of dynamic susceptibility contrast MRI perfusion data
CONCLUSION: These results support that the proposed SPINNED method can be a good alternative to the existing methods for resolving the deconvolution problem in DSC MRI. The proposed method does not require any separate ground-truth measurement for training and offers additional benefits of quick processing time and coverage of diverse clinical scenarios. Consequently, it will contribute to more reliable, accurate, and rapid diagnoses in clinical applications compared with the previous methods including those based on supervised learning.PMID:38623911 | DOI:10.1002/mrm.30095 (Source: Magnetic Resonance in Medicine)
Source: Magnetic Resonance in Medicine - April 16, 2024 Category: Radiology Authors: Muhammad Asaduddin Eung Yeop Kim Sung-Hong Park Source Type: research

Prediction of postoperative cerebral infarction after combined bypass surgery in adult moyamoya disease: combining quantitative parameters on RAPID perfusion CT with clinically related factors
CONCLUSIONS: For adult patients with MMD and a large volume of Tmax > 6 sec over 59.5 ml, more caution is required when deciding to undergo bypass surgery and in postoperative management.PMID:38626473 | DOI:10.3171/2024.1.JNS232641 (Source: Journal of Neurosurgery)
Source: Journal of Neurosurgery - April 16, 2024 Category: Neurosurgery Authors: Si Un Lee Yongjae Lee Tae Won Choi Sang Hyo Lee Young-Deok Kim Seung Pil Ban O-Ki Kwon Chang Wan Oh Jae Seung Bang Source Type: research

SPINNED: Simulation-based physics-informed neural network for deconvolution of dynamic susceptibility contrast MRI perfusion data
CONCLUSION: These results support that the proposed SPINNED method can be a good alternative to the existing methods for resolving the deconvolution problem in DSC MRI. The proposed method does not require any separate ground-truth measurement for training and offers additional benefits of quick processing time and coverage of diverse clinical scenarios. Consequently, it will contribute to more reliable, accurate, and rapid diagnoses in clinical applications compared with the previous methods including those based on supervised learning.PMID:38623911 | DOI:10.1002/mrm.30095 (Source: Magnetic Resonance in Medicine)
Source: Magnetic Resonance in Medicine - April 16, 2024 Category: Radiology Authors: Muhammad Asaduddin Eung Yeop Kim Sung-Hong Park Source Type: research

Prediction of postoperative cerebral infarction after combined bypass surgery in adult moyamoya disease: combining quantitative parameters on RAPID perfusion CT with clinically related factors
CONCLUSIONS: For adult patients with MMD and a large volume of Tmax > 6 sec over 59.5 ml, more caution is required when deciding to undergo bypass surgery and in postoperative management.PMID:38626473 | DOI:10.3171/2024.1.JNS232641 (Source: Journal of Neurosurgery)
Source: Journal of Neurosurgery - April 16, 2024 Category: Neurosurgery Authors: Si Un Lee Yongjae Lee Tae Won Choi Sang Hyo Lee Young-Deok Kim Seung Pil Ban O-Ki Kwon Chang Wan Oh Jae Seung Bang Source Type: research

Isolated Fragments of Intact Microvessels: Tissue Vascularization, Modeling, and Therapeutics
ABSTRACTThe microvasculature is integral to nearly every tissue in the body, providing not only perfusion to and from the tissue, but also homing sites for immune cells, cellular niches for tissue dynamics, and cooperative interactions with other tissue elements. As a microtissue itself, the microvasculature is a composite of multiple cell types exquisitely organized into structures (individual vessel segments and extensive vessel networks) capable of considerable dynamics and plasticity. Consequently, it has been challenging to include a functional microvasculature in assembled or fabricated tissues. Isolated fragments of...
Source: Microcirculation - April 16, 2024 Category: Research Authors: Hannah  A. Strobel, Sarah M. Moss, James B. Hoying Tags: REVIEW Source Type: research

Post-ductal coarctation of aorta aneurysm repair in adult via left antero-axillary thoracotomy with antegrade cerebral perfusion —a case series
We describe our experience in managing three such patients through antero-lateral thoracotomy with antegrade cerebral perfusion. We have found this technique helpful in treating aneurysms of the distal aortic arch or proximal descending thoracic aorta. (Source: Indian Journal of Thoracic and Cardiovascular Surgery)
Source: Indian Journal of Thoracic and Cardiovascular Surgery - April 16, 2024 Category: Cardiovascular & Thoracic Surgery Source Type: research

ESR Essentials: imaging in stable chest pain – practice recommendations by ESCR
AbstractStable chest pain is a common symptom with multiple potential causes. Non-invasive imaging has an important role in diagnosis and guiding management through the assessment of coronary stenoses, atherosclerotic plaque, myocardial ischaemia or infarction, and cardiac function. Computed tomography (CT) provides the anatomical evaluation of coronary artery disease (CAD) with the assessment of stenosis, plaque type and plaque burden, with additional functional information available from CT fractional flow reserve (FFR) or CT myocardial perfusion imaging. Stress magnetic resonance imaging, nuclear stress myocardial perfu...
Source: European Radiology - April 16, 2024 Category: Radiology Source Type: research

Is Kinesio taping acutely effective for peripheral tissue perfusion in women with mild to moderate chronic venous insufficiency? A randomized controlled trial
Objective To evaluate the acute effect of Kinesio Taping ® (KT) on peripheral tissue perfusion in women with chronic venous insufficiency (CVI). Methods: This randomized, double-blind controlled trial included 59 women with mild to moderate CVI. They were randomized to a control group (n = 23; 54.08 ± 9.04 years) and KT group (n = 36; 55.87 ± 9.97 years). Near-infrared spectroscopy was positioned in the medial gastrocnemius muscle for assessment of resting tissue perfusion 48 h after the first day of evaluation and after placement of the Kinesio Taping® tape. (Source: Journal of Bodywork and Movement Therapies)
Source: Journal of Bodywork and Movement Therapies - April 16, 2024 Category: Physiotherapy Authors: Maria Luiza Vieira Carvalho, Viviane De Menezes Caceres, Isabella de Oliveira Nascimento, Henrique Silveira Costa, Pedro Henrique Schedit Figueiredo, Vanessa Pereira Lima, Debora Pantuso Monteiro, Danielle Aparecida Gomes Pereira Source Type: research

Cancers, Vol. 16, Pages 1519: Contrast Agent Dynamics Determine Radiomics Profiles in Oncologic Imaging
Conclusions: CT and MRI radiomics features in both prostate and lung tumors are significantly affected by interindividual differences in contrast agent dynamics. (Source: Cancers)
Source: Cancers - April 16, 2024 Category: Cancer & Oncology Authors: Martin L. Watzenboeck Lucian Beer Daria Kifjak Sebastian R öhrich Benedikt H. Heidinger Florian Prayer Ruxandra-Iulia Milos Paul Apfaltrer Georg Langs Pascal A. T. Baltzer Helmut Prosch Tags: Article Source Type: research

Cerebellar blood perfusion is a diagnostic, but not a prognostic, marker for parkinsonian-dominant type multiple system atrophy.
Multiple system atrophy (MSA) is clinically characterized by various neurological symptoms. According to the diagnostic criteria, MSA is classified into parkinsonian-dominant type (MSA-P) or cerebellar ataxia-dominant type (MSA-C) based on the predominant signs displayed. Recently, N-isopropyl-p-[123I] iodoamphetamine (123I-IMP) single-photon emission computed tomography (SPECT), a radiological examination evaluating brain perfusion, has been successful in detecting cerebellar hypoperfusion in MSA-P patients, demonstrating its utility in the early detection of cerebellar dysfunction. (Source: Parkinsonism and Related Disorders)
Source: Parkinsonism and Related Disorders - April 16, 2024 Category: Neurology Authors: Kenta Shiina, Taiji Tsunemi, Nobutaka Hattori Source Type: research

Cuboid Bone for Distal Radius Reconstruction: An Anatomical Cadaver Study
Conclusion The CB presented reasonable anatomical similarities with the DR and a long and consistent pedicle with an adequate blood supply observed during ICG injection. Clinical Relevance This study supports the possibility of using the CB as a vascularized bone transfer for autologous reconstruction of the articular surface of the DR. Further study is warranted. [...] Thieme Medical Publishers, Inc. 333 Seventh Avenue, 18th Floor, New York, NY 10001, USAArticle in Thieme eJournals: Table of contents  |  Abstract  |  Full text (Source: Journal of Wrist Surgery)
Source: Journal of Wrist Surgery - April 16, 2024 Category: Orthopaedics Authors: Alvedro-Ruiz, Pedro Trapero-Ovejero, Ana Ferr às-Tarragó, Joan P érez-García, Alberto Valverde-Navarro, Alfonso Thione, Alessandro Tags: Scientific Article Source Type: research

Longitudinal alterations in brain perfusion and vascular reactivity in the zQ175DN mouse model of Huntington ’s disease
Huntington ’s disease (HD) is marked by a CAG-repeat expansion in the huntingtin gene that causes neuronal dysfunction and loss, affecting mainly the striatum and the cortex. Alterations in the neurovascular co... (Source: Journal of Biomedical Science)
Source: Journal of Biomedical Science - April 16, 2024 Category: Biomedical Science Authors: Tamara Vasilkovska, Somaie Salajeghe, Verdi Vanreusel, Johan Van Audekerke, Marlies Verschuuren, Lydiane Hirschler, Jan Warnking, Isabel Pintelon, Dorian Pustina, Roger Cachope, Ladislav Mrzljak, Ignacio Mu ñoz-Sanjuan, Emmanuel L. Barbier, Winnok H. De Tags: Research Source Type: research

Multiparametric ultrasound as a new concept of assessment of liver tissue damage
World J Gastroenterol. 2024 Mar 28;30(12):1663-1669. doi: 10.3748/wjg.v30.i12.1663.ABSTRACTLiver disease accounts for approximately 2 million deaths per year worldwide. All chronic liver diseases (CLDs), whether of toxic, genetic, autoimmune, or infectious origin, undergo typical histological changes in the structure of the tissue. These changes may include the accumulation of extracellular matrix material, fats, triglycerides, or tissue scarring. Noninvasive methods for diagnosing CLD, such as conventional B-mode ultrasound (US), play a significant role in diagnosis. Doppler US, when coupled with B-mode US, can be helpful...
Source: World Journal of Gastroenterology : WJG - April 15, 2024 Category: Gastroenterology Authors: Angela Peltec Ioan Sporea Source Type: research