Parathyroid carcinoma - a study of 29 cases
CONCLUSIONS: A diagnosis of parathyroid carcinoma should always be considered during surgery in patients diagnosed with primary hyperparathyroidism, especially in patients with severe hypercalcaemia, significantly enlarged neck circumference, and concomitant diseases of the renal and skeletal system. Parathyroid carcinoma is rarely definitively diagnosed preoperatively or even intraoperatively, and the final diagnosis can be made exclusively after operation. The optimal treatment is a complete surgical resection at a reference centre - specialized in parathyroid surgery - to improve outcomes and provide the best chance of ...
Source: Endokrynologia Polska - February 14, 2022 Category: Endocrinology Authors: Grzegorz J ózef Kowalski Adam Bednarczyk Grzegorz Bu ła Agata Gawrychowska Jacek Gawrychowski Source Type: research
Parathyroid carcinoma - a study of 29 cases
CONCLUSIONS: A diagnosis of parathyroid carcinoma should always be considered during surgery in patients diagnosed with primary hyperparathyroidism, especially in patients with severe hypercalcaemia, significantly enlarged neck circumference, and concomitant diseases of the renal and skeletal system. Parathyroid carcinoma is rarely definitively diagnosed preoperatively or even intraoperatively, and the final diagnosis can be made exclusively after operation. The optimal treatment is a complete surgical resection at a reference centre - specialized in parathyroid surgery - to improve outcomes and provide the best chance of ...
Source: Endokrynologia Polska - February 14, 2022 Category: Endocrinology Authors: Grzegorz J ózef Kowalski Adam Bednarczyk Grzegorz Bu ła Agata Gawrychowska Jacek Gawrychowski Source Type: research
Parathyroid carcinoma - a study of 29 cases
CONCLUSIONS: A diagnosis of parathyroid carcinoma should always be considered during surgery in patients diagnosed with primary hyperparathyroidism, especially in patients with severe hypercalcaemia, significantly enlarged neck circumference, and concomitant diseases of the renal and skeletal system. Parathyroid carcinoma is rarely definitively diagnosed preoperatively or even intraoperatively, and the final diagnosis can be made exclusively after operation. The optimal treatment is a complete surgical resection at a reference centre - specialized in parathyroid surgery - to improve outcomes and provide the best chance of ...
Source: Endokrynologia Polska - February 14, 2022 Category: Endocrinology Authors: Grzegorz J ózef Kowalski Adam Bednarczyk Grzegorz Bu ła Agata Gawrychowska Jacek Gawrychowski Source Type: research
Parathyroid carcinoma - a study of 29 cases
CONCLUSIONS: A diagnosis of parathyroid carcinoma should always be considered during surgery in patients diagnosed with primary hyperparathyroidism, especially in patients with severe hypercalcaemia, significantly enlarged neck circumference, and concomitant diseases of the renal and skeletal system. Parathyroid carcinoma is rarely definitively diagnosed preoperatively or even intraoperatively, and the final diagnosis can be made exclusively after operation. The optimal treatment is a complete surgical resection at a reference centre - specialized in parathyroid surgery - to improve outcomes and provide the best chance of ...
Source: Endokrynologia Polska - February 14, 2022 Category: Endocrinology Authors: Grzegorz J ózef Kowalski Adam Bednarczyk Grzegorz Bu ła Agata Gawrychowska Jacek Gawrychowski Source Type: research
Parathyroid carcinoma - a study of 29 cases
CONCLUSIONS: A diagnosis of parathyroid carcinoma should always be considered during surgery in patients diagnosed with primary hyperparathyroidism, especially in patients with severe hypercalcaemia, significantly enlarged neck circumference, and concomitant diseases of the renal and skeletal system. Parathyroid carcinoma is rarely definitively diagnosed preoperatively or even intraoperatively, and the final diagnosis can be made exclusively after operation. The optimal treatment is a complete surgical resection at a reference centre - specialized in parathyroid surgery - to improve outcomes and provide the best chance of ...
Source: Endokrynologia Polska - February 14, 2022 Category: Endocrinology Authors: Grzegorz J ózef Kowalski Adam Bednarczyk Grzegorz Bu ła Agata Gawrychowska Jacek Gawrychowski Source Type: research
Parathyroid carcinoma - a study of 29 cases
CONCLUSIONS: A diagnosis of parathyroid carcinoma should always be considered during surgery in patients diagnosed with primary hyperparathyroidism, especially in patients with severe hypercalcaemia, significantly enlarged neck circumference, and concomitant diseases of the renal and skeletal system. Parathyroid carcinoma is rarely definitively diagnosed preoperatively or even intraoperatively, and the final diagnosis can be made exclusively after operation. The optimal treatment is a complete surgical resection at a reference centre - specialized in parathyroid surgery - to improve outcomes and provide the best chance of ...
Source: Endokrynologia Polska - February 14, 2022 Category: Endocrinology Authors: Grzegorz J ózef Kowalski Adam Bednarczyk Grzegorz Bu ła Agata Gawrychowska Jacek Gawrychowski Source Type: research
Parathyroid carcinoma - a study of 29 cases
CONCLUSIONS: A diagnosis of parathyroid carcinoma should always be considered during surgery in patients diagnosed with primary hyperparathyroidism, especially in patients with severe hypercalcaemia, significantly enlarged neck circumference, and concomitant diseases of the renal and skeletal system. Parathyroid carcinoma is rarely definitively diagnosed preoperatively or even intraoperatively, and the final diagnosis can be made exclusively after operation. The optimal treatment is a complete surgical resection at a reference centre - specialized in parathyroid surgery - to improve outcomes and provide the best chance of ...
Source: Endokrynologia Polska - February 14, 2022 Category: Endocrinology Authors: Grzegorz J ózef Kowalski Adam Bednarczyk Grzegorz Bu ła Agata Gawrychowska Jacek Gawrychowski Source Type: research
Parathyroid carcinoma - a study of 29 cases
CONCLUSIONS: A diagnosis of parathyroid carcinoma should always be considered during surgery in patients diagnosed with primary hyperparathyroidism, especially in patients with severe hypercalcaemia, significantly enlarged neck circumference, and concomitant diseases of the renal and skeletal system. Parathyroid carcinoma is rarely definitively diagnosed preoperatively or even intraoperatively, and the final diagnosis can be made exclusively after operation. The optimal treatment is a complete surgical resection at a reference centre - specialized in parathyroid surgery - to improve outcomes and provide the best chance of ...
Source: Endokrynologia Polska - February 14, 2022 Category: Endocrinology Authors: Grzegorz J ózef Kowalski Adam Bednarczyk Grzegorz Bu ła Agata Gawrychowska Jacek Gawrychowski Source Type: research
Parathyroid carcinoma - a study of 29 cases
CONCLUSIONS: A diagnosis of parathyroid carcinoma should always be considered during surgery in patients diagnosed with primary hyperparathyroidism, especially in patients with severe hypercalcaemia, significantly enlarged neck circumference, and concomitant diseases of the renal and skeletal system. Parathyroid carcinoma is rarely definitively diagnosed preoperatively or even intraoperatively, and the final diagnosis can be made exclusively after operation. The optimal treatment is a complete surgical resection at a reference centre - specialized in parathyroid surgery - to improve outcomes and provide the best chance of ...
Source: Endokrynologia Polska - February 14, 2022 Category: Endocrinology Authors: Grzegorz J ózef Kowalski Adam Bednarczyk Grzegorz Bu ła Agata Gawrychowska Jacek Gawrychowski Source Type: research
Parathyroid carcinoma - a study of 29 cases
CONCLUSIONS: A diagnosis of parathyroid carcinoma should always be considered during surgery in patients diagnosed with primary hyperparathyroidism, especially in patients with severe hypercalcaemia, significantly enlarged neck circumference, and concomitant diseases of the renal and skeletal system. Parathyroid carcinoma is rarely definitively diagnosed preoperatively or even intraoperatively, and the final diagnosis can be made exclusively after operation. The optimal treatment is a complete surgical resection at a reference centre - specialized in parathyroid surgery - to improve outcomes and provide the best chance of ...
Source: Endokrynologia Polska - February 14, 2022 Category: Endocrinology Authors: Grzegorz J ózef Kowalski Adam Bednarczyk Grzegorz Bu ła Agata Gawrychowska Jacek Gawrychowski Source Type: research
An approach to a patient with primary hyperparathyroidism and a suspected ectopic parathyroid adenoma
J Clin Endocrinol Metab. 2022 Feb 12:dgac024. doi: 10.1210/clinem/dgac024. Online ahead of print.ABSTRACTPrimary hyperparathyroidism (PHPT) is characterised by hypercalcemia driven by excess parathyroid hormone (PTH) secretion. PHPT is a common endocrine condition with a prevalence of one to seven cases per 1000 adults. PHPT typically presents in the fifth or sixth decade and shows significant female preponderance. Solitary hyper-functioning parathyroid adenomas account for 85-90% of PHPT cases. The remaining 10-15% include cases of multi-glandular disease (multiple adenomas or hyperplasia) and, rarely, parathyroid carcino...
Source: The Journal of Clinical Endocrinology and Metabolism - February 12, 2022 Category: Endocrinology Authors: Clarke Glasgow Eunice Y C Lau Luigi Aloj Ines Harper Heok Cheow Tilak Das Laurence Berman Andrew S Powlson Waiel Bashari Benjamin G Challis Alison Marker Penelope Moyle Isra Mohamed Nadia Schoenmakers Jonathan Broomfield Sue Oddy Carla Moran Mark Gurnell Source Type: research
An approach to a patient with primary hyperparathyroidism and a suspected ectopic parathyroid adenoma
J Clin Endocrinol Metab. 2022 Feb 12:dgac024. doi: 10.1210/clinem/dgac024. Online ahead of print.ABSTRACTPrimary hyperparathyroidism (PHPT) is characterised by hypercalcemia driven by excess parathyroid hormone (PTH) secretion. PHPT is a common endocrine condition with a prevalence of one to seven cases per 1000 adults. PHPT typically presents in the fifth or sixth decade and shows significant female preponderance. Solitary hyper-functioning parathyroid adenomas account for 85-90% of PHPT cases. The remaining 10-15% include cases of multi-glandular disease (multiple adenomas or hyperplasia) and, rarely, parathyroid carcino...
Source: The Journal of Clinical Endocrinology and Metabolism - February 12, 2022 Category: Endocrinology Authors: Clarke Glasgow Eunice Y C Lau Luigi Aloj Ines Harper Heok Cheow Tilak Das Laurence Berman Andrew S Powlson Waiel Bashari Benjamin G Challis Alison Marker Penelope Moyle Isra Mohamed Nadia Schoenmakers Jonathan Broomfield Sue Oddy Carla Moran Mark Gurnell Source Type: research
Cancers, Vol. 14, Pages 876: MicroRNA Profile Alterations in Parathyroid Carcinoma: Latest Updates and Perspectives
Siewko
Parathyroid tumors are a genetically heterogenous group with a significant variability in clinical features. Due to a lack of specific signs and symptoms and uncertain histopathological criteria, parathyroid carcinomas (PCs) are challenging to diagnose, both before and after surgery. There is a great interest in searching for accurate molecular biomarkers for early detection, disease monitoring, and clinical management. Due to improvements in molecular pathology, the latest studies have reported that PC tumorigenesis is strongly linked to the epigenetic regulation of gene expression. MicroRNA (miRNA) profiling ...
Source: Cancers - February 10, 2022 Category: Cancer & Oncology Authors: Marta Wielog órska Beata Podg órska Magdalena Niemira Ma łgorzata Szelachowska Adam Kr ętowski Katarzyna Siewko Tags: Review Source Type: research
A Bibliometric Analysis of the Landscape of Parathyroid Carcinoma Research Based on the PubMed (2000 –2021)
ConclusionThere are huge unmet research needs for parathyroid carcinoma. Improving the diagnosis rates of parathyroid cancer by clinicians and establishing new and reliable molecular pathological markers and new image localization techniques will continue to be the focus of future research. (Source: Frontiers in Oncology)
Source: Frontiers in Oncology - February 7, 2022 Category: Cancer & Oncology Source Type: research
Denosumab for the Treatment of Hypercalcemia in a Patient With Parathyroid Carcinoma: A Case Report
We report another case of refractory hypercalcemia treated with several doses of denosumab in a patient with parathyroid carcinoma. (Source: Frontiers in Endocrinology)
Source: Frontiers in Endocrinology - January 31, 2022 Category: Endocrinology Source Type: research
