Approach to the Patient With Parathyroid Carcinoma
We describe herein a patient with severe PHPT due to PC and provide a systematic diagnostic and treatment approach. A thorough review of the medical history, a typical clinical and biochemical phenotype and, in some cases, the revision of the histological examination provide the clues for the diagnosis of PC.PMID:37531615 | DOI:10.1210/clinem/dgad455 (Source: The Journal of Clinical Endocrinology and Metabolism)
Source: The Journal of Clinical Endocrinology and Metabolism - August 2, 2023 Category: Endocrinology Authors: Filomena Cetani Elena Pardi Liborio Torregrossa Simona Borsari Laura Pierotti Elisa Dinoi Claudio Marcocci Source Type: research
Approach to the Patient With Parathyroid Carcinoma
We describe herein a patient with severe PHPT due to PC and provide a systematic diagnostic and treatment approach. A thorough review of the medical history, a typical clinical and biochemical phenotype and, in some cases, the revision of the histological examination provide the clues for the diagnosis of PC.PMID:37531615 | DOI:10.1210/clinem/dgad455 (Source: The Journal of Clinical Endocrinology and Metabolism)
Source: The Journal of Clinical Endocrinology and Metabolism - August 2, 2023 Category: Endocrinology Authors: Filomena Cetani Elena Pardi Liborio Torregrossa Simona Borsari Laura Pierotti Elisa Dinoi Claudio Marcocci Source Type: research
Parathyroid cancer with MTOR gene mutation: Case report and review of the literature
Ann Endocrinol (Paris). 2023 Jun 24:S0003-4266(23)00117-8. doi: 10.1016/j.ando.2023.06.003. Online ahead of print.NO ABSTRACTPMID:37500361 | DOI:10.1016/j.ando.2023.06.003 (Source: Annales d'Endocrinologie)
Source: Annales d'Endocrinologie - July 27, 2023 Category: Endocrinology Authors: J úlia Stark Judit T őke Gergely Huszty P éter Nagy G ábor Bedics Csaba B ödör J ózsef Tímár Mikl ós Tóth Source Type: research
Parathyroid cancer with MTOR gene mutation: Case report and review of the literature
Ann Endocrinol (Paris). 2023 Jun 24:S0003-4266(23)00117-8. doi: 10.1016/j.ando.2023.06.003. Online ahead of print.NO ABSTRACTPMID:37500361 | DOI:10.1016/j.ando.2023.06.003 (Source: Annales d'Endocrinologie)
Source: Annales d'Endocrinologie - July 27, 2023 Category: Endocrinology Authors: J úlia Stark Judit T őke Gergely Huszty P éter Nagy G ábor Bedics Csaba B ödör J ózsef Tímár Mikl ós Tóth Source Type: research
Parathyroid cancer with MTOR gene mutation: Case report and review of the literature
Ann Endocrinol (Paris). 2023 Jun 24:S0003-4266(23)00117-8. doi: 10.1016/j.ando.2023.06.003. Online ahead of print.NO ABSTRACTPMID:37500361 | DOI:10.1016/j.ando.2023.06.003 (Source: Annales d'Endocrinologie)
Source: Annales d'Endocrinologie - July 27, 2023 Category: Endocrinology Authors: J úlia Stark Judit T őke Gergely Huszty P éter Nagy G ábor Bedics Csaba B ödör J ózsef Tímár Mikl ós Tóth Source Type: research
Parathyroid cancer with MTOR gene mutation: Case report and review of the literature
Ann Endocrinol (Paris). 2023 Jun 24:S0003-4266(23)00117-8. doi: 10.1016/j.ando.2023.06.003. Online ahead of print.NO ABSTRACTPMID:37500361 | DOI:10.1016/j.ando.2023.06.003 (Source: Annales d'Endocrinologie)
Source: Annales d'Endocrinologie - July 27, 2023 Category: Endocrinology Authors: J úlia Stark Judit T őke Gergely Huszty P éter Nagy G ábor Bedics Csaba B ödör J ózsef Tímár Mikl ós Tóth Source Type: research
Diagnostic dilemma in a rare case of nonfunctional parathyroid carcinoma at a referral facility in Northern Tanzania
Photography of the patient showing a huge palpable parathyroid tumour with infiltration of the overlying skin (A); Gross appearance of the resected tumour specimen (B). Key Clinical MessageRare cancer originating from parathyroid parenchymal cells. Preoperative diagnosis is often difficult. Presents with normal serum levels of calcium and parathyroid hormone. Treated by en bloc resection. Benefits of adjuvant therapy are unclear.AbstractParathyroid carcinoma is an uncommon endocrine tumor. Its typical presentation is that of primary hyperparathyroidism with elevated serum calcium and parathormone levels. Nonfunctioning car...
Source: Clinical Case Reports - July 22, 2023 Category: General Medicine Authors: Alex Mremi,
Michael Kayuza,
Patrick Amsi,
Marco Magwizi,
Desderius Chussi Tags: CASE REPORT Source Type: research
Investigating the risk of metabolic and cardiovascular comorbidities among patients with parathyroid cancer: a nationwide representative cohort study in Taiwan
This study aimed to determine whether primary parathyroid cancer patients were associated with increased metabolic and cardiovascular comorbidities in comparison to the general population. (Source: BMC Medicine)
Source: BMC Medicine - July 10, 2023 Category: Internal Medicine Authors: Ming-Chieh Tsai, Min-Shu Hsu, Hsin-Yin Hsu, Tzu-Lin Yeh, Chun-Ju Chiang, Wen-Chung Lee, Jing-Rong Jhuang, Shih-Ping Cheng, Po-Jung Tseng and Kuo-Liong Chien Tags: Research article Source Type: research
Hypercalcemia in metastatic parathyroid carcinoma followed by hypocalcemia after resection: A case report
Parathyroid carcinoma is rare. This is a valuable case in which the serum calcium level was controlled by surgery. The patient also developed post-operative hypocalcaemia, which should be reported. AbstractA 72-year-old man was diagnosed with hypercalcaemia 13 years ago. He was diagnosed with hyperparathyroidism associated with a parathyroid tumour and surgery was performed. Postoperatively, his serum calcium levels, which had once normalized, rose again. Medical treatment for hypercalcaemia failed to control the condition. A chest computed tomography showed multiple pulmonary nodules which were diagnosed as pulmonary m...
Source: Respirology Case Reports - July 4, 2023 Category: Respiratory Medicine Authors: Takuya Ohashi,
Mitsumasa Kawago,
Yoshimitsu Hirai,
Yumi Yata,
Aya Fusamoto,
Hideto Iguchi,
Takahito Nakaya,
Megumi Kiyoi,
Miwako Miyasaka,
Mari Kawaji,
Yuki Furuta,
Yoshiharu Nishimura Tags: CASE REPORT Source Type: research
Reticular fibre structure in the differential diagnosis of parathyroid neoplasms
To investigate the characteristics of reticular fibre structure (RFS) in parathyroid adenoma (PTA), atypical parathyroid tumour (APT), and parathyroid carcinoma (PTC), and to assess its value as a diagnostic i... (Source: Diagnostic Pathology)
Source: Diagnostic Pathology - July 4, 2023 Category: Pathology Authors: Xiumei Hu, Shurong He, Xingran Jiang, Ping Wei, Xiang Zhou, Zhongyue Shi, Xue Li, Jun Lu, Hongying Zhao, Bojun Wei and Mulan Jin Tags: Research Source Type: research
A parathyroid cancer with soporous state, depression, and severe cognitive decline in acute renal failure
This report describes a case of parathyroid carcinoma (PC) with an uncommon first clinical presentation: soporous state, depression, and severe cognitive decline in association with acute renal failure. After discovering extremely high serum calcium and parathyroid hormone (PTH) levels, the diagnosis of primary hyperparathyroidism (pHPT) was made and a surgical en bloc resection was performed. After the surgical intervention, the histological examination revealed the presence of a malignant parathyroid disease, thus confirming our first preoperative suspicion. (Source: Clinical Case Reports)
Source: Clinical Case Reports - June 30, 2023 Category: General Medicine Authors: Federica Vultaggio,
Barbara Martino,
Letizia Nitro,
Emanuela Fuccillo,
Giovanni Felisati,
Loredana De Pasquale Tags: CASE REPORT Source Type: research
Phenotypic Profiling and Molecular Mechanisms in Hyperparathyroidism-Jaw Tumor Syndrome
CONCLUSIONS: Multiple, recurrent atypical adenomyomatous uterine polyps appear to be enriched in women with HPT-JT and appear characteristic of the disease. Patients with CDC73 variants at p.M1 residue appear predisposed to kidney tumors.PMID:37339334 | DOI:10.1210/clinem/dgad368 (Source: The Journal of Clinical Endocrinology and Metabolism)
Source: The Journal of Clinical Endocrinology and Metabolism - June 20, 2023 Category: Endocrinology Authors: Rana Tora James Welch Jian Sun Sunita K Agarwal Debra A Bell Maria Merino Lee S Weinstein William F Simonds Smita Jha Source Type: research
Phenotypic Profiling and Molecular Mechanisms in Hyperparathyroidism-Jaw Tumor Syndrome
CONCLUSIONS: Multiple, recurrent atypical adenomyomatous uterine polyps appear to be enriched in women with HPT-JT and appear characteristic of the disease. Patients with CDC73 variants at p.M1 residue appear predisposed to kidney tumors.PMID:37339334 | DOI:10.1210/clinem/dgad368 (Source: The Journal of Clinical Endocrinology and Metabolism)
Source: The Journal of Clinical Endocrinology and Metabolism - June 20, 2023 Category: Endocrinology Authors: Rana Tora James Welch Jian Sun Sunita K Agarwal Debra A Bell Maria Merino Lee S Weinstein William F Simonds Smita Jha Source Type: research
