Parathyroid Disorders
Am Fam Physician. 2022 Mar 1;105(3):289-298.ABSTRACTParathyroid disorders are most often identified incidentally by abnormalities in serum calcium levels when screening for renal or bone disease or other conditions. Parathyroid hormone, which is released by the parathyroid glands primarily in response to low calcium levels, stimulates osteoclastic bone resorption and serum calcium elevation, reduces renal calcium clearance, and stimulates intestinal calcium absorption through synthesis of 1,25-dihydroxyvitamin D. Primary hyperparathyroidism, in which calcium levels are elevated without appropriate suppression of parathyroi...
Source: American Family Physician - March 15, 2022 Category: Primary Care Authors: Jarrett Sell Sarah Ramirez Michael Partin Source Type: research
Parathyroid Disorders
Am Fam Physician. 2022 Mar 1;105(3):289-298.ABSTRACTParathyroid disorders are most often identified incidentally by abnormalities in serum calcium levels when screening for renal or bone disease or other conditions. Parathyroid hormone, which is released by the parathyroid glands primarily in response to low calcium levels, stimulates osteoclastic bone resorption and serum calcium elevation, reduces renal calcium clearance, and stimulates intestinal calcium absorption through synthesis of 1,25-dihydroxyvitamin D. Primary hyperparathyroidism, in which calcium levels are elevated without appropriate suppression of parathyroi...
Source: American Family Physician - March 15, 2022 Category: Primary Care Authors: Jarrett Sell Sarah Ramirez Michael Partin Source Type: research
Parathyroid Disorders
Am Fam Physician. 2022 Mar 1;105(3):289-298.ABSTRACTParathyroid disorders are most often identified incidentally by abnormalities in serum calcium levels when screening for renal or bone disease or other conditions. Parathyroid hormone, which is released by the parathyroid glands primarily in response to low calcium levels, stimulates osteoclastic bone resorption and serum calcium elevation, reduces renal calcium clearance, and stimulates intestinal calcium absorption through synthesis of 1,25-dihydroxyvitamin D. Primary hyperparathyroidism, in which calcium levels are elevated without appropriate suppression of parathyroi...
Source: American Family Physician - March 15, 2022 Category: Primary Care Authors: Jarrett Sell Sarah Ramirez Michael Partin Source Type: research
Parathyroid Disorders
Am Fam Physician. 2022 Mar 1;105(3):289-298.ABSTRACTParathyroid disorders are most often identified incidentally by abnormalities in serum calcium levels when screening for renal or bone disease or other conditions. Parathyroid hormone, which is released by the parathyroid glands primarily in response to low calcium levels, stimulates osteoclastic bone resorption and serum calcium elevation, reduces renal calcium clearance, and stimulates intestinal calcium absorption through synthesis of 1,25-dihydroxyvitamin D. Primary hyperparathyroidism, in which calcium levels are elevated without appropriate suppression of parathyroi...
Source: American Family Physician - March 15, 2022 Category: Primary Care Authors: Jarrett Sell Sarah Ramirez Michael Partin Source Type: research
Parathyroid Disorders
Am Fam Physician. 2022 Mar 1;105(3):289-298.ABSTRACTParathyroid disorders are most often identified incidentally by abnormalities in serum calcium levels when screening for renal or bone disease or other conditions. Parathyroid hormone, which is released by the parathyroid glands primarily in response to low calcium levels, stimulates osteoclastic bone resorption and serum calcium elevation, reduces renal calcium clearance, and stimulates intestinal calcium absorption through synthesis of 1,25-dihydroxyvitamin D. Primary hyperparathyroidism, in which calcium levels are elevated without appropriate suppression of parathyroi...
Source: American Family Physician - March 15, 2022 Category: Primary Care Authors: Jarrett Sell Sarah Ramirez Michael Partin Source Type: research
Parathyroid Disorders
Am Fam Physician. 2022 Mar 1;105(3):289-298.ABSTRACTParathyroid disorders are most often identified incidentally by abnormalities in serum calcium levels when screening for renal or bone disease or other conditions. Parathyroid hormone, which is released by the parathyroid glands primarily in response to low calcium levels, stimulates osteoclastic bone resorption and serum calcium elevation, reduces renal calcium clearance, and stimulates intestinal calcium absorption through synthesis of 1,25-dihydroxyvitamin D. Primary hyperparathyroidism, in which calcium levels are elevated without appropriate suppression of parathyroi...
Source: American Family Physician - March 15, 2022 Category: Primary Care Authors: Jarrett Sell Sarah Ramirez Michael Partin Source Type: research
Parathyroid Disorders
Am Fam Physician. 2022 Mar 1;105(3):289-298.ABSTRACTParathyroid disorders are most often identified incidentally by abnormalities in serum calcium levels when screening for renal or bone disease or other conditions. Parathyroid hormone, which is released by the parathyroid glands primarily in response to low calcium levels, stimulates osteoclastic bone resorption and serum calcium elevation, reduces renal calcium clearance, and stimulates intestinal calcium absorption through synthesis of 1,25-dihydroxyvitamin D. Primary hyperparathyroidism, in which calcium levels are elevated without appropriate suppression of parathyroi...
Source: American Family Physician - March 15, 2022 Category: Primary Care Authors: Jarrett Sell Sarah Ramirez Michael Partin Source Type: research
Re: Hyperparathyroidism Due to Concurrent Parathyroid Carcinoma and Parathyroid Adenoma
No abstract available (Source: Clinical Nuclear Medicine)
Source: Clinical Nuclear Medicine - March 10, 2022 Category: Nuclear Medicine Tags: Letters to the Editor Source Type: research
Hyperparathyroidism Due to Concurrent Parathyroid Carcinoma and Parathyroid Adenoma: Reply
No abstract available (Source: Clinical Nuclear Medicine)
Source: Clinical Nuclear Medicine - March 10, 2022 Category: Nuclear Medicine Tags: Letters to the Editor Source Type: research
Cancers, Vol. 14, Pages 1426: Parathyroid Carcinoma: Incidence, Survival Analysis, and Management: A Study from the SEER Database and Insights into Future Therapeutic Perspectives
Conclusion: PC is a very rare tumor mostly affecting Caucasian individuals in the fifth decade. Older age, poor histologic differentiation, and distant metastasis are associated with a worse prognosis. Surgical resection offers the best survival outcome. To better understand the pathogenesis and factors affecting survival, all PC patients should be enrolled in national and international registries. (Source: Cancers)
Source: Cancers - March 10, 2022 Category: Cancer & Oncology Authors: Asad Ullah Jaffar Khan Abdul Waheed Nitasha Sharma Elizabeth K. Pryor Tanner R. Stumpe Luis Velasquez Zarate Frederick D. Cason Suresh Kumar Subhasis Misra Sravan Kavuri Hector Mesa Nitin Roper Shahin Foroutan Nabin Raj Karki Jaydira Del Rivero William F. Tags: Article Source Type: research
Genetics and Epigenetics of Parathyroid Carcinoma
Parathyroid carcinoma (PC) is an extremely rare malignancy, accounting less than 1% of all parathyroid neoplasms, and an uncommon cause of primary hyperparathyroidism (PHPT), characterized by an excessive secretion of parathyroid hormone (PTH) and severe hypercalcemia. As opposed to parathyroid hyperplasia and adenomas, PC is associated with a poor prognosis, due to a commonly unmanageable hypercalcemia, which accounts for death in the majority of cases, and an overall survival rate of 78-85% and 49-70% at 5 and 10 years after diagnosis, respectively. No definitively effective therapies for PC are currently available. The ...
Source: Frontiers in Endocrinology - February 24, 2022 Category: Endocrinology Source Type: research
Atypical parathyroid adenoma: Severe manifestations in an adolescent girl
CONCLUSIONS: Atypical parathyroid adenoma, a rare cause of PHPT, may be associated with severe manifestations. Although malignancy was not discerned in the immediate post-operative period, we plan to continue long-term follow-up of the patient to look for any signs of recurrence or development of parathyroid carcinoma.PMID:35193332 | DOI:10.5114/pedm.2021.109127 (Source: Pediatric Endocrinology, Diabetes, and Metabolism)
Source: Pediatric Endocrinology, Diabetes, and Metabolism - February 23, 2022 Category: Endocrinology Authors: Hiya Boro Sarah Alam Vijay Kubihal Saurav Khatiwada Suraj Kubihal Shipra Agarwal Rajesh Khadgawat Source Type: research
Atypical parathyroid adenoma: Severe manifestations in an adolescent girl
CONCLUSIONS: Atypical parathyroid adenoma, a rare cause of PHPT, may be associated with severe manifestations. Although malignancy was not discerned in the immediate post-operative period, we plan to continue long-term follow-up of the patient to look for any signs of recurrence or development of parathyroid carcinoma.PMID:35193332 | DOI:10.5114/pedm.2021.109127 (Source: Pediatric Endocrinology, Diabetes, and Metabolism)
Source: Pediatric Endocrinology, Diabetes, and Metabolism - February 23, 2022 Category: Endocrinology Authors: Hiya Boro Sarah Alam Vijay Kubihal Saurav Khatiwada Suraj Kubihal Shipra Agarwal Rajesh Khadgawat Source Type: research
Atypical parathyroid adenoma: Severe manifestations in an adolescent girl
CONCLUSIONS: Atypical parathyroid adenoma, a rare cause of PHPT, may be associated with severe manifestations. Although malignancy was not discerned in the immediate post-operative period, we plan to continue long-term follow-up of the patient to look for any signs of recurrence or development of parathyroid carcinoma.PMID:35193332 | DOI:10.5114/pedm.2021.109127 (Source: Pediatric Endocrinology, Diabetes, and Metabolism)
Source: Pediatric Endocrinology, Diabetes, and Metabolism - February 23, 2022 Category: Endocrinology Authors: Hiya Boro Sarah Alam Vijay Kubihal Saurav Khatiwada Suraj Kubihal Shipra Agarwal Rajesh Khadgawat Source Type: research
Atypical parathyroid adenoma: Severe manifestations in an adolescent girl
CONCLUSIONS: Atypical parathyroid adenoma, a rare cause of PHPT, may be associated with severe manifestations. Although malignancy was not discerned in the immediate post-operative period, we plan to continue long-term follow-up of the patient to look for any signs of recurrence or development of parathyroid carcinoma.PMID:35193332 | DOI:10.5114/pedm.2021.109127 (Source: Pediatric Endocrinology, Diabetes, and Metabolism)
Source: Pediatric Endocrinology, Diabetes, and Metabolism - February 23, 2022 Category: Endocrinology Authors: Hiya Boro Sarah Alam Vijay Kubihal Saurav Khatiwada Suraj Kubihal Shipra Agarwal Rajesh Khadgawat Source Type: research
