Log in to search using one of your social media accounts:

 

Complementary and alternative medicine in Brazilian children and adolescents with type 1 diabetes mellitus.
CONCLUSIONS: The construction of the profile revealed a group of patients that deserve a special attention by health professionals because they are more prone to adopt behaviors that impair the success of the treatment, such as not counting carbohydrates and not informing the doctor about the use of CAM. PMID: 29073288 [PubMed - in process] (Source: Pediatric Endocrinology, Diabetes, and Metabolism)
Source: Pediatric Endocrinology, Diabetes, and Metabolism - October 28, 2017 Category: Endocrinology Authors: Machado LCB, Alves C Tags: Pediatr Endocrinol Diabetes Metab Source Type: research

PM10 concentration and microbiological assessment of air in relation to the number of acute cases of type 1 diabetes mellitus in the Lubelskie Voivodeship. Preliminary report.
Abstract INTRODUCTION: The aim of our study was to evaluate the relation between the concentration of particulate matter of less than 10 μm in diameter (PM10) in air and the effect of psychrophilic bacteria, mesophilic bacteria and mould fungi on the number of new cases of type 1 diabetes mellitus in children and adolescents in the Lubelskie Voivodeship in the years 2015-2016. PATIENTS AND METHODS: Epidemiological data on the number of new cases of T1DM was obtained from the Department of Paediatric Endocrinology and Diabetology of the Medical University in Lublin. The number of births for the year 2015 an...
Source: Pediatric Endocrinology, Diabetes, and Metabolism - October 28, 2017 Category: Endocrinology Authors: Michalska M, Bartoszewicz M, Wąż P, Kozaczuk S, Beń-Skowronek I, Zorena K Tags: Pediatr Endocrinol Diabetes Metab Source Type: research

Nutritional status at the moment of diagnosis in childhood cancer patients.
Abstract INTRODUCTION: Children with a neoplastic disease are highly susceptible to malnutrition. The main objective of the study was to assess the frequency of undernourishment and obesity at the time of the diagnosis of the neoplastic disease at children. MATERIALS AND METHODS: The study included 734 patients (58% males) at the age 1-20,25, with the diagnosis of neoplasm in the years 1986-2014. The patients were divided into groups depending on the type of the diagnosis: 1) ALL, 2) ANLL, 3) HL, 4) NHL, 5) NBL, 6) Wilms tumor, 7) mesenchymal malignant tumor. The BMI SDS and the height SDS were evaluated. The...
Source: Pediatric Endocrinology, Diabetes, and Metabolism - October 28, 2017 Category: Endocrinology Authors: Połubok J, Malczewska A, Rąpała M, Szymocha J, Kozicka M, Dubieńska K, Duczek M, Kazanowska B, Barg E Tags: Pediatr Endocrinol Diabetes Metab Source Type: research

[Direction of change in the somatic development in children and adolescents with type 1 diabetes].
CONCLUSIONS: Changes in body build in patients with diabetes type 1 are associated with chronological age, duration of disease and metabolic control. It has been observed that the increase of weight and waist circumference concern girls. Patients with overweight and obesity represent a risk of early development of complications and require special care. PMID: 29073291 [PubMed - in process] (Source: Pediatric Endocrinology, Diabetes, and Metabolism)
Source: Pediatric Endocrinology, Diabetes, and Metabolism - October 28, 2017 Category: Endocrinology Authors: Kołodziejczyk H, Wajda-Cuszlag M, Świercz A, Szalecki M Tags: Pediatr Endocrinol Diabetes Metab Source Type: research

TOFI phenotype - its effect on the occurrence of diabetes.
Abstract Recent studies have reported a significant increase in the incidence of type 2 diabetes in the past 30 years. They also predict that this trend will continue. This is related to a change in lifestyle, which results in a parallel increase in the incidence of overweight and obesity. However, symptoms of the metabolic syndrome, so far closely related to abdominal obesity, are relatively common among people with normal body mass index (BMI) and waist circumference. The aim of the study is to present the TOFI phenotype (thin outside, fat inside) as an important factor in pathogenesis of type 2 diabetes. In the...
Source: Pediatric Endocrinology, Diabetes, and Metabolism - October 28, 2017 Category: Endocrinology Authors: Zdrojewicz Z, Popowicz E, Szyca M, Michalik T, Śmieszniak B Tags: Pediatr Endocrinol Diabetes Metab Source Type: research

Prader-Willi Syndrome - nutritional management in children, adolescents and adults.
Abstract Prader-Willi Syndrome is a genetic condition caused by an abnormality of chromosome 15, mostly resulting from a deletion.The prevalence of syndrome in Europe has been reported between 1 in 8,000 to 1 in 45,000 births. Characteristic features of the syndrome include hypotonia, short stature, psychomotor development delay, hypogonadism and progressive, life-threatening obesity. Treatment of Prader-Willi Syndrome consists of intensive rehabilitation, psychologicalcare, speech therapy and also, if patient is fulfilling appropriate criteria, growth hormone treatment. An extremely important element of therapy i...
Source: Pediatric Endocrinology, Diabetes, and Metabolism - October 28, 2017 Category: Endocrinology Authors: Krasińska A, Skowrońska B Tags: Pediatr Endocrinol Diabetes Metab Source Type: research

Previously unreported abnormalities in Wolfram Syndrome Type 2.
We report possible additional clinical and laboratory findings that have not been pre-viously reported, such as asymptomatic hypoparathyroidism, osteomalacia, growth hormone (GH) deficiency and hepatomegaly. Even though not a requirement for the diagnosis of WFS2 currently, our case series confirm hypogonadotropic hypogonadism to be also a feature of this syndrome, as reported before. PMID: 29073294 [PubMed - in process] (Source: Pediatric Endocrinology, Diabetes, and Metabolism)
Source: Pediatric Endocrinology, Diabetes, and Metabolism - October 28, 2017 Category: Endocrinology Authors: Akturk Md HK, Yasa MSc S Tags: Pediatr Endocrinol Diabetes Metab Source Type: research

[Early enzyme replacement therapy - hope for patients with mucopolysaccharidosis Type II].
We present an unexpected outcome of 10 years of enzyme replacement therapy of a boy with mucopolysaccharidosis type II. Due to a positive familiar history (severe disease course in a sibling) the diagnosis was established in the first month of life. Treatment with Elaprase was introduced two months later. Since then normal physical and mental development is observed. The patient presents only relatively large head circumference (+2.1 SD) and slight decrease of joints mobility. In our opinion, early introduction of enzyme replecement therapy could attenuate the disease course. PMID: 29073295 [PubMed - in process] (Sour...
Source: Pediatric Endocrinology, Diabetes, and Metabolism - October 28, 2017 Category: Endocrinology Authors: Orchel-Szastak K, Ptak K, Hrnciar K, Pilch B, Kania U, Bik-Multanowski M Tags: Pediatr Endocrinol Diabetes Metab Source Type: research

Potential Clinical Benefits of a Two-bag System for Fluid Management in Pediatric Intensive Care Unit Patients with Diabetic Ketoacidosis.
CONCLUSION: The two-bag system is associated with lower incidence of hypoglycemia and faster discharge from the PICU. We recommend that clinicians consider using the two-bag system for fluid management in pediatric patients with diabetic ketoacidosis. PMID: 29073302 [PubMed - in process] (Source: Pediatric Endocrinology, Diabetes, and Metabolism)
Source: Pediatric Endocrinology, Diabetes, and Metabolism - October 28, 2017 Category: Endocrinology Authors: Velasco Md JP, Fogel PhD J, Levine Md PhD RL, Ciminera Md P, Fagan Md D, Bargman Md R Tags: Pediatr Endocrinol Diabetes Metab Source Type: research

Significant differences in parameters of glucose metabolism in children of hypertensive and normotensive parents.
Abstract INTRODUCTION: In the recent years, alterations in the carbohydrate metabolism, including insulin resistance, are considered as risk factors in the development of hypertension and its complications in young age. Hypertension is associated with significant cardiovascular morbidity and mortality. The onset of pathology responsible for the development of hypertension, as well as levels of biomarkers specific for early stages of atherosclerosis are poorly understood. AIM: To compare a group of children whose parents have a history of hypertension (study group) with a group of children with normotensive pa...
Source: Pediatric Endocrinology, Diabetes, and Metabolism - October 28, 2017 Category: Endocrinology Authors: Gryko A, Głowińska-Olszewska B, Płudowska K, Smithson WH, Owłasiuk A, Żelazowska-Rutkowska B, Wojtkielewicz K, Milewski R, Chlabicz S Tags: Pediatr Endocrinol Diabetes Metab Source Type: research

Environmental factors affecting management of type 1 diabetes in children below the age of 10.
Abstract INTRODUCTION: The way parents manage diabetes of their small children and environmental influence are crucial for maintaining glycemic control. The aim of the study was to assess environmental factors affecting metabolic control of young children with T1D treated with insulin pumps. MATERIAL AND METHODS: Parents of children with T1D under the age of 10 years completed: General Self-Efficacy Scale, Parental Diabetes Quality of Life Questionnaire, Beck Depression Inventory and a questionnaire on socioeconomic factors. RESULTS: There were analyzed 165 questionnaires. 66% of children achieved HbA1c
Source: Pediatric Endocrinology, Diabetes, and Metabolism - October 28, 2017 Category: Endocrinology Authors: Piechowiak K, Zduńczyk B, Szypowska A Tags: Pediatr Endocrinol Diabetes Metab Source Type: research

[Topinambour - nutritional and medical properties of the Jerusalem artichoke (Helianthus tuberoses L.)].
Abstract Topinambour (Helianthus tuberosus L.), also known as the Jerusalem artichoke is a plant, which origins from North America. In XVII century it was brought to the Europe. For ages it was cultivated due to edible tuber and its healing properties.The aim of the article is to present medical properties and application of topinmbour in patient's diet. Many studies were performed on animals to specify medical properties of topinambour. Results show, that topinambour lowers plasma glucose, total cholesterol and triglyceride levels. It is believed that these effects are caused by high level of inulin present it it...
Source: Pediatric Endocrinology, Diabetes, and Metabolism - October 28, 2017 Category: Endocrinology Authors: Horochowska M, Kołeczek E, Zdrojewicz Z, Jagiełło J, Pawlus K Tags: Pediatr Endocrinol Diabetes Metab Source Type: research

[Y chromosome in Turner syndrome].
Abstract Turner syndrome (TS) is an inherited genetic disorder caused by numerical and/or structural chromosome X aberrations occurring at a frequency of 1:1200-1:2500 live-born girls. The most common karyotype is X chromosome monosomy (45,X) (approximately 50-60% of cases). Approximately 5-6% of patients may have abnormal Y chromosome or mosaicism characterized by the coexistence of 45,X cell line with cell line in which all or part of chromosome Y is present. In patients with TS who have all or fragmented genetic material from chromosome Y there is a substantial risk of cancerous lesions in these dysgenetic gona...
Source: Pediatric Endocrinology, Diabetes, and Metabolism - October 28, 2017 Category: Endocrinology Authors: Rojek A, Kwasiuk K, Obara-Moszyńska M, Kolesińska Z, Niedziela M Tags: Pediatr Endocrinol Diabetes Metab Source Type: research

A follow-up history of young man with apparent cortisone reductase deficiency (ACRD) - several years after diagnosis.
CONCLUSIONS: Hydrocortisone treatment is ineffective in ACRD patients because it was rapidly metabolized to cortisone. We have found the balance between the dexamethasone treatment effects of adrenal suppression and the achievement of full height potential considering the condition of our patient. PMID: 29073307 [PubMed - in process] (Source: Pediatric Endocrinology, Diabetes, and Metabolism)
Source: Pediatric Endocrinology, Diabetes, and Metabolism - October 28, 2017 Category: Endocrinology Authors: Zajkowska A, Rydzewska M, Wojtkielewicz K, Pomaski J, Romer T, Bossowski A Tags: Pediatr Endocrinol Diabetes Metab Source Type: research

15-Year old girl with APS type IIIc, 12 months post-thymectomy remission of myasthenia.
We describe a teenage female patient - with the family history of autoimmune diseases, who has simultaneously developed the symptoms of autoimmune thyroid disease with the clinical picture of hyperthyroidism and myasthenia gravis at the age of fifteen. Graves' disease was diagnosed approximately 2 months before myasthenia. Co-occurance of those two diseases allowed us to diagnose PAS type IIIC, however it caused specific diagnostic and treatment difficulties. Furthermore, several months after the diagnosis the patient was found to be GAD-Ab positive, whilst the glycaemic control remained normal. No evidence of other autoim...
Source: Pediatric Endocrinology, Diabetes, and Metabolism - October 28, 2017 Category: Endocrinology Authors: Jamiołkowska M, Bossowski A Tags: Pediatr Endocrinol Diabetes Metab Source Type: research

Zesp ół Silvera-Rusella. Część II.
Zespół Silvera-Rusella. Część II. Pediatr Endocrinol Diabetes Metab. 2016 Jun 8;21(3):132-42 Authors: Kalina MA, Tańska A, Marczak-Hałupka A, Chrzanowska KH PMID: 27275769 [PubMed - in process] (Source: Pediatric Endocrinology, Diabetes, and Metabolism)
Source: Pediatric Endocrinology, Diabetes, and Metabolism - June 7, 2016 Category: Endocrinology Authors: Kalina MA, Tańska A, Marczak-Hałupka A, Chrzanowska KH Tags: Pediatr Endocrinol Diabetes Metab Source Type: research

Assessment of ghrelin, leptin, orexin A and alpha-MSH serum concentrations and the levels of the autoantibodies against the aforementioned peptides in relation to Helicobacter pylori infections and Candida albicans colonization in children with short stature.
PMID: 27275765 [PubMed - in process] (Source: Pediatric Endocrinology, Diabetes, and Metabolism)
Source: Pediatric Endocrinology, Diabetes, and Metabolism - June 7, 2016 Category: Endocrinology Authors: Stawerska R, Czkwianianc E, Matusiak A, Smyczyńska J, Hilczer M, Chmiela M, Lewiński A Tags: Pediatr Endocrinol Diabetes Metab Source Type: research

[Body mass and body length of warsaw's newborns].
PMID: 27275766 [PubMed - in process] (Source: Pediatric Endocrinology, Diabetes, and Metabolism)
Source: Pediatric Endocrinology, Diabetes, and Metabolism - June 7, 2016 Category: Endocrinology Authors: Milde K, Wiśniewski A, Gyrczuk E, Tomaszewski P, Sienkiewicz-Dianzenza E, Stupnicki R Tags: Pediatr Endocrinol Diabetes Metab Source Type: research

[Screening in specific categories of neonates exposed to congenital hypothyroidism].
PMID: 27275767 [PubMed - in process] (Source: Pediatric Endocrinology, Diabetes, and Metabolism)
Source: Pediatric Endocrinology, Diabetes, and Metabolism - June 7, 2016 Category: Endocrinology Authors: Beń-Skowronek I, Kucharska A, Hilczer M, Ołtarzewski M, Szalecki M, Walczak M, Jackowska T, Lewiński A, Bossowski A Tags: Pediatr Endocrinol Diabetes Metab Source Type: research

[The treatment and monitoring of the therapy of congenital hypothyroidism].
PMID: 27275768 [PubMed - in process] (Source: Pediatric Endocrinology, Diabetes, and Metabolism)
Source: Pediatric Endocrinology, Diabetes, and Metabolism - June 7, 2016 Category: Endocrinology Authors: Kucharska AM, Beń-Skowronek I, Walczak M, Petriczko E, Jackowska T, Lewiński A, Bossowski A Tags: Pediatr Endocrinol Diabetes Metab Source Type: research

Zespół Silvera-Rusella. Część II.
Zespół Silvera-Rusella. Część II. Pediatr Endocrinol Diabetes Metab. 2016 Jun 8;21(3):132-42 Authors: Kalina MA, Tańska A, Marczak-Hałupka A, Chrzanowska KH PMID: 27275769 [PubMed - in process] (Source: Pediatric Endocrinology, Diabetes, and Metabolism)
Source: Pediatric Endocrinology, Diabetes, and Metabolism - June 7, 2016 Category: Endocrinology Authors: Kalina MA, Tańska A, Marczak-Hałupka A, Chrzanowska KH Tags: Pediatr Endocrinol Diabetes Metab Source Type: research

[Dental abnormalities and orthodontic disorders in Turner's syndrome patients].
PMID: 27275770 [PubMed - in process] (Source: Pediatric Endocrinology, Diabetes, and Metabolism)
Source: Pediatric Endocrinology, Diabetes, and Metabolism - June 7, 2016 Category: Endocrinology Authors: Borkowska M, Gawlik A, Hankus M, Małecka-Tendera E Tags: Pediatr Endocrinol Diabetes Metab Source Type: research

Evaluation of selected endocrine disorders after anticancer treatment of solid tumors in childhood.
PMID: 26901137 [PubMed - as supplied by publisher] (Source: Pediatric Endocrinology, Diabetes, and Metabolism)
Source: Pediatric Endocrinology, Diabetes, and Metabolism - February 18, 2016 Category: Endocrinology Authors: Połubok J, Gonera A, Jasielska O, Sęga-Pondel D, Galant K, Kazanowska B, Barg E Tags: Pediatr Endocrinol Diabetes Metab Source Type: research

Reasons for the discontinuation of therapy of personal insulin pump in children with type 1 diabetes.
CONCLUSIONS: The individual psycho-emotional state of the child and appropriate education are important at the start and continuation of CSII. PMID: 26901138 [PubMed - as supplied by publisher] (Source: Pediatric Endocrinology, Diabetes, and Metabolism)
Source: Pediatric Endocrinology, Diabetes, and Metabolism - February 18, 2016 Category: Endocrinology Authors: Binek A, Rembierz-Knoll A, Polańska J, Jarosz-Chobot P Tags: Pediatr Endocrinol Diabetes Metab Source Type: research

[Overweight, obesity and lipids abnormalities in adolescents with type 1 diabetes].
CONCLUSIONS: The most important risk factor for obesity in adolescents with type 1 diabetes is female gender. Lipids profile is closely dependent on metabolic control and mass excess. Diabetes duration, metabolic control and lipids profile are significant risk factors for overweight and abdominal obesity. PMID: 26901139 [PubMed - as supplied by publisher] (Source: Pediatric Endocrinology, Diabetes, and Metabolism)
Source: Pediatric Endocrinology, Diabetes, and Metabolism - February 18, 2016 Category: Endocrinology Authors: Wysocka-Mincewicz M, Kołodziejczyk H, Wierzbicka E, Szalecki M Tags: Pediatr Endocrinol Diabetes Metab Source Type: research

[New onset diabetes after transplantation].
PMID: 26901140 [PubMed - as supplied by publisher] (Source: Pediatric Endocrinology, Diabetes, and Metabolism)
Source: Pediatric Endocrinology, Diabetes, and Metabolism - February 18, 2016 Category: Endocrinology Authors: Wysocka-Mincewicz M, Szalecki M Tags: Pediatr Endocrinol Diabetes Metab Source Type: research

LPL gene mutation as the cause of severe hypertriglyceridemia in the course of ketoacidosis in a patient with newly diagnosed type 1 diabetes mellitus.
CONCLUSION: In patient with T1DM the diagnosis of severe hypertriglyceridemia in the course of ketoacidosis should be based on careful interpretation of laboratory tests results. Moreover genetic tests of the patient and his/her immediate relatives blood samples should be performed. PMID: 26901141 [PubMed - as supplied by publisher] (Source: Pediatric Endocrinology, Diabetes, and Metabolism)
Source: Pediatric Endocrinology, Diabetes, and Metabolism - February 18, 2016 Category: Endocrinology Authors: Nocoń-Bohusz J, Wikiera B, Basiak A, Śmigiel R, Noczyńska A Tags: Pediatr Endocrinol Diabetes Metab Source Type: research

Down syndrome and hyperthyroidism - two case reports.
PMID: 26901142 [PubMed - as supplied by publisher] (Source: Pediatric Endocrinology, Diabetes, and Metabolism)
Source: Pediatric Endocrinology, Diabetes, and Metabolism - February 18, 2016 Category: Endocrinology Authors: Szatkowska M, Zimny D, Barg E Tags: Pediatr Endocrinol Diabetes Metab Source Type: research

[Birth weight of newborns and health behaviours and haematological parameters of pregnant women - results of preliminary studies].
PMID: 26901040 [PubMed - as supplied by publisher] (Source: Pediatric Endocrinology, Diabetes, and Metabolism)
Source: Pediatric Endocrinology, Diabetes, and Metabolism - December 15, 2015 Category: Endocrinology Authors: Suliga E, Adamczyk-Gruszka O Tags: Pediatr Endocrinol Diabetes Metab Source Type: research

[Are children from resort spa healthy? The overweight and obesity in children from Kudowa-Zdrój].
[Are children from resort spa healthy? The overweight and obesity in children from Kudowa-Zdrój]. Pediatr Endocrinol Diabetes Metab. 2015 Dec 15;21(1):15-22 Authors: Połubok J, Gonera A, Ubysz J, Wójcik M, Kozicka M, Barg E Abstract ABSTRACT: Overweight and obesity are becoming a more and more common problem among children and teenagers. AIM: . The aim of this study is to evaluate the development of children and teenagers from Kudowa-Zdroj and to assess the prevalence of overweight and obesity in this population. MATERIALS AND METHODS: . The study included 545 children, aged 5...
Source: Pediatric Endocrinology, Diabetes, and Metabolism - December 15, 2015 Category: Endocrinology Authors: Połubok J, Gonera A, Ubysz J, Wójcik M, Kozicka M, Barg E Tags: Pediatr Endocrinol Diabetes Metab Source Type: research

[Assessments of dietary patterns of children aged 10-12 in the city of Olsztyn].
CONCLUSIONS: The study results showed the mistakes made by the studied population group in the method of nutrition, including daily diet energy value (deficiencies), its structure and the quality of the meals. PMID: 26901042 [PubMed - as supplied by publisher] (Source: Pediatric Endocrinology, Diabetes, and Metabolism)
Source: Pediatric Endocrinology, Diabetes, and Metabolism - December 15, 2015 Category: Endocrinology Authors: Hałacz J, Warechowska M Tags: Pediatr Endocrinol Diabetes Metab Source Type: research

Metabolicsyndrome in youngpatients.
PMID: 26901043 [PubMed - as supplied by publisher] (Source: Pediatric Endocrinology, Diabetes, and Metabolism)
Source: Pediatric Endocrinology, Diabetes, and Metabolism - December 15, 2015 Category: Endocrinology Authors: Otto-Buczkowska E, Dryżałowski M Tags: Pediatr Endocrinol Diabetes Metab Source Type: research

[Gene polymorphism and dyslipidemias].
PMID: 26901044 [PubMed - as supplied by publisher] (Source: Pediatric Endocrinology, Diabetes, and Metabolism)
Source: Pediatric Endocrinology, Diabetes, and Metabolism - December 15, 2015 Category: Endocrinology Authors: Czajka M, Rachubik P, Rzeszutek J, Matysiak M, Kruszewski M, Kapka-Skrzypczak L Tags: Pediatr Endocrinol Diabetes Metab Source Type: research

[Congenital hyperinsulinism: course and consequences - case report].
PMID: 26901045 [PubMed - as supplied by publisher] (Source: Pediatric Endocrinology, Diabetes, and Metabolism)
Source: Pediatric Endocrinology, Diabetes, and Metabolism - December 15, 2015 Category: Endocrinology Authors: Gonera A, Buraczewska M, Borowiec M, Barg E Tags: Pediatr Endocrinol Diabetes Metab Source Type: research

The Pro12Ala PPARg2 gene polymorphism involves residual C-peptide secretionand BMI in type 1 diabetes.
CONCLUSIONS: Thus, it is likely that PPARg2 gene polymorphism and/or the genetically determined insulin resistance may be associated with residual C-peptide secretion and involve excessive BMI in type 1 diabetes. PMID: 26615044 [PubMed - as supplied by publisher] (Source: Pediatric Endocrinology, Diabetes, and Metabolism)
Source: Pediatric Endocrinology, Diabetes, and Metabolism - August 31, 2015 Category: Endocrinology Authors: Zmyslowska A, Szadkowska A, Mianowska B, Pietrzak I, Wyka K, Mlynarski W Tags: Pediatr Endocrinol Diabetes Metab Source Type: research

The impact of having siblings - analysis of "hygiene theory" of chronic diseases in patients with type 1 diabetes in population of the Łódz region Hygiene theory and type 1 diabetes.
The impact of having siblings - analysis of "hygiene theory" of chronic diseases in patients with type 1 diabetes in population of the Łódz region Hygiene theory and type 1 diabetes. Pediatr Endocrinol Diabetes Metab. 2015 Aug 31;20(3):95-100 Authors: Żurawska-Kliś M, Lesman J, Pietrzak I, Mianowska B, Szadkowska A, Cypryk K Abstract INTRODUCTION: In the recent years there has been a significant increase in the incidence of the type 1 diabetes mellitus. Therefore, numerous studies are underway to evaluate the possible factors underlying this trend. Some studies suggest that better ...
Source: Pediatric Endocrinology, Diabetes, and Metabolism - August 31, 2015 Category: Endocrinology Authors: Żurawska-Kliś M, Lesman J, Pietrzak I, Mianowska B, Szadkowska A, Cypryk K Tags: Pediatr Endocrinol Diabetes Metab Source Type: research

Silver-Russell Syndrome - Part I: Clinical Characteristics and Genetic Background.
Abstract Silver-Russell syndrome (SRS) is a rare, clinically and genetically heterogeneous entity, caused by (epi)genetic alternations. It is characterized by prenatal and postnatal growth retardation, relative macrocephaly, the triangular face and body asymmetry. About 40-60% of cases are caused by hypomethylation of 11p.15.5 Imprinting Centre Region 1 (ICR1) on the paternal chromosome, and maternal uniparental disomy for chromosome 7 (UPD(7)mat) is found in 5-10% of cases. There are suggested correlations between genotype and the phenotype. Psychomotor development may be delayed, usually mildly, with school diff...
Source: Pediatric Endocrinology, Diabetes, and Metabolism - August 31, 2015 Category: Endocrinology Authors: Marczak-Hałupka A, Kalina MA, Tańska A, Chrzanowska KH Tags: Pediatr Endocrinol Diabetes Metab Source Type: research

[Insulin resistance in children].
Abstract Insulin resistance is the state of reduced tissue sensitivity to insulin. The frequency of this occurrence is increasing dramatically in developed countries. Both, environmental and genetic factors are involved in the pathogenesis of insulin resistance. Sedentary lifestyle and the excessive calorie intake cause the substantial increase of the fat issue, leading to overweight and obesity. Insulin resistance occurs physiologically during puberty, but it is also a pathological condition predisposing children to develop abnormal glucose tolerance, diabetes, hypertension and polycystic ovary syndrome among gir...
Source: Pediatric Endocrinology, Diabetes, and Metabolism - August 31, 2015 Category: Endocrinology Authors: Stąpor N, Beń-Skowronek I Tags: Pediatr Endocrinol Diabetes Metab Source Type: research

[Transition of young adults with type 1 diabetes mellitus from a pediatric to adult diabetes clinic - problems, challenges and recommendations].
Abstract ABSTRACT: Type 1 diabetes is a chronic disease associated with the risk of acute and chronic complications. The patients with type 1 diabetes require constant monitoring in a diabetes outpatient clinic, regardless of their age, and the cessation of diabetes care may result in deterioration of metabolic control and earlier development of chronic complications. When the children grow up and reach 18 years of age, they must transfer from the custody of the pediatric outpatient clinic to the care of adult diabetes center. This is a very important time in the life of a young patient. When the transition is wel...
Source: Pediatric Endocrinology, Diabetes, and Metabolism - August 31, 2015 Category: Endocrinology Authors: Modrzyńska K, Szadkowska A Tags: Pediatr Endocrinol Diabetes Metab Source Type: research

[Suspicion of anorexia nervosa as a cause of delayed diagnosis of brain tumor. A case report].
Abstract Tumors of the central nervous system (CNS) are the most common solid tumors diagnosed in children. The most frequent symptoms of brain tumors in this age group are headaches and vomiting, regardless of the location of the lesions. These symptoms are non-specific, and in each case require differential diagnosis, especially if there is no gradual improvement in the patient's condition or progression. The most common signs of anorexia nervosa are chronic vomiting, weakness of the body, pain and in extreme cases cachexia. These symptoms are similar to the clinical image of CNS tumor. Teenager, described in ou...
Source: Pediatric Endocrinology, Diabetes, and Metabolism - August 31, 2015 Category: Endocrinology Authors: Niedzielska E, Węcławek-Tompol J, Kazanowska B, Barg E Tags: Pediatr Endocrinol Diabetes Metab Source Type: research

[Assessment of selected anthropometric parameters in children exposed to gestational diabetes in utero - preliminary results].
CONCLUSIONS: Excessive body weight before pregnancy in mothers with gestational diabetes can influence not only the anthropometric parameters of newborns and lead to fetal macrosomy, but also can be a predisposing factor for overweight and obesity in later childhood. PMID: 26615012 [PubMed - as supplied by publisher] (Source: Pediatric Endocrinology, Diabetes, and Metabolism)
Source: Pediatric Endocrinology, Diabetes, and Metabolism - July 31, 2015 Category: Endocrinology Authors: Wilk M, Horodnicka-Józwa A, Molęda P, Petriczko E, Ciechanowski P, Safranow K, Walczak M Tags: Pediatr Endocrinol Diabetes Metab Source Type: research

[Risk factors for cardiovascular disease in children with type 1 diabetes in 2000-2010 in Podlasie Province].
CONCLUSIONS: Contemporary patients frequently have excessive body weight and live in families burdened with risk factors for atherosclerosis. Despite the use of modern technology, metabolic control is not satisfactory. PMID: 26615013 [PubMed - as supplied by publisher] (Source: Pediatric Endocrinology, Diabetes, and Metabolism)
Source: Pediatric Endocrinology, Diabetes, and Metabolism - July 31, 2015 Category: Endocrinology Authors: Polkowska A, Głowińska-Olszewska B, Tobiaszewska M, Bossowski A Tags: Pediatr Endocrinol Diabetes Metab Source Type: research

[The use of metabolomics in medicine - some examples of oncological and metabolic diseases].
Abstract Metabolomics is a new field of medicine focused on examining and analyzing metabolites produced in biological cells. Biological fluids primarily used in this method include: plasma, cerebrospinal fluid, saliva and urine. The most common methods of evaluating the composition involve nuclear magnetic resonance (NMR) and magnetic resonance (MR) with addition of gas chromatography (GC-MS) or liquid chromatography (LC-MS). Metabolomics is used in a wide variety of medicine disciplines. The variability of biochemical processes in tumor cells in comparison to normal cells is the starting point of such studies. T...
Source: Pediatric Endocrinology, Diabetes, and Metabolism - July 31, 2015 Category: Endocrinology Authors: Zimny D, Szatkowska M, Połubok J, Maciaszek J, Machaj M, Barg E Tags: Pediatr Endocrinol Diabetes Metab Source Type: research

[The clinical utility of C-peptide measurement in diabetology].
Abstract C-peptide is produced in equal amounts to insulin and is the best measure of endogenous insulin secretion in patients with diabetes. Measurement of insulin secretion using C-peptide can be helpful in clinical practice: differences in insulin secretion are fundamental to different requirements in the treatment of diabetes. An important clinical role of C-peptide is differentiating between type 1 and type 2 diabetes. Low basal C-peptide can be considered as criterion for transferring the patients, initially diagnosed as type 2 diabetes, in the type 1 diabetes group. C-peptide level may be a good predictor o...
Source: Pediatric Endocrinology, Diabetes, and Metabolism - July 31, 2015 Category: Endocrinology Authors: Otto-Buczkowska E Tags: Pediatr Endocrinol Diabetes Metab Source Type: research

[Cardiometabolic risk factors in Turner syndrome].
Abstract Congenital cardiovascular structural abnormalities, hypertension, low birth weight, increased prevalence of obesity, frequent glucose intolerance and dyslipidemia are risk factors of premature mortality for cardiovascular events in Turner syndrome (TS). The life expectancy in TS is reduced by at least 10 years and the risk of premature death is increased 3-fold compared to general female population. Hormonal therapy in TS, both estrogens in different algorithms and growth hormone in supraphysiological dose, may additionally modify these factors. In this review we summarize cardiometabolic markers potentia...
Source: Pediatric Endocrinology, Diabetes, and Metabolism - July 31, 2015 Category: Endocrinology Authors: Gawlik A, Gieburowska J, Małecka-Tendera E Tags: Pediatr Endocrinol Diabetes Metab Source Type: research

Growth hormone therapy in a girl with Turner syndrome and diabetes type 1 - case report.
CONCLUSIONS: The decision of rGH therapy in TS with diabetes is certainly difficult. While starting the growth hormone treatment the clinician must keep in mind the risk of metabolic complications, but also the awareness that gives the patient a chance to improve the final height. In terms of the proper psycho-emotional development the reduction of growth deficit is very important. PMID: 26615017 [PubMed - as supplied by publisher] (Source: Pediatric Endocrinology, Diabetes, and Metabolism)
Source: Pediatric Endocrinology, Diabetes, and Metabolism - July 31, 2015 Category: Endocrinology Authors: Obara-Moszynska M, Banaszak M, Niedziela M Tags: Pediatr Endocrinol Diabetes Metab Source Type: research

[Nutrients as inflammatory state modulators].
Abstract The role of diet in reduction of the risk of chronic diseases such as cardiovascular diseases, diabetes mellitus, obesity, and metabolic syndrome has been widely documented. There is evidence that the link between diet and this kind of diseases is low grade chronic inflammation induced by some nutrients. Inflammation is a natural defense mechanism which helps to avoid tissue injuries caused by biological, physical and chemical factors. Adequate inflammatory process is defined by intensity and duration. As a chronic state (silent inflammation, low grade chronic inflammation), it became an etiologic factor ...
Source: Pediatric Endocrinology, Diabetes, and Metabolism - January 1, 2013 Category: Endocrinology Authors: Kapka-Skrzypczak L, Niedźwiecka J, Skrzypczak M, Kruszewski M Tags: Pediatr Endocrinol Diabetes Metab Source Type: research