Pediatric Endocrinology, Diabetes, and Metabolism
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Potential bacteriophages to overcome bacterial infection of Alcaligenes faecalis in diabetic ulcer
CONCLUSIONS: The 6 isolates that were isolated had the ability to infect by forming a prophage that could inhibit the growth of Alcaligenes faecalis and other pathogenic bacteria in diabetic ulcers.PMID:37728456 | PMC:PMC10411081 | DOI:10.5114/pedm.2023.125363 (Source: Pediatric Endocrinology, Diabetes, and Metabolism)
Source: Pediatric Endocrinology, Diabetes, and Metabolism - September 20, 2023 Category: Endocrinology Authors: Erlia Narulita Vivi Indah Nur Cahyati Riska A Febrianti Mochammad Iqbal Source Type: research
Assessment of fibroblast growth factor 21 in children with type 1 diabetes mellitus in relation to microvascular complications
CONCLUSIONS: FGF21 is significantly higher among children with DM1 than in controls. However, its role in diabetic microvascular complica-tions needs further assessment.PMID:37728457 | PMC:PMC10411091 | DOI:10.5114/pedm.2022.121372 (Source: Pediatric Endocrinology, Diabetes, and Metabolism)
Source: Pediatric Endocrinology, Diabetes, and Metabolism - September 20, 2023 Category: Endocrinology Authors: Nermien Tantawy Eman Sherif Randa M Matter Nouran Salah Nour Eldin Abozeid Heba Atif Source Type: research
Are menstrual disorders in adolescent girls related to metabolic disorders?
CONCLUSIONS: Adolescent girls with menstrual disorders are insulin resistant, regardless of PCOS diagnosis. The severity of menstrual disorders may be related to the incidence of lipid disorders in adolescent girls.PMID:37728458 | PMC:PMC10411084 | DOI:10.5114/pedm.2023.125364 (Source: Pediatric Endocrinology, Diabetes, and Metabolism)
Source: Pediatric Endocrinology, Diabetes, and Metabolism - September 20, 2023 Category: Endocrinology Authors: El żbieta Foryś Adrianna Baran Aleksandra Dziurdzia Ewelina Jarosz-W ójcik Pawe ł Matusik Aneta Gawlik Ryszard Tomaszewski Agnieszka Zachurzok Source Type: research
The positive impact of lifestyle intervention on selected mio- and chemokines levels in prepubertal children with obesity
CONCLUSIONS: Personalized diet modification and regular, daily exercises may positively influence on the levels of irisin and chemerin.PMID:37728459 | PMC:PMC10411087 | DOI:10.5114/pedm.2023.127273 (Source: Pediatric Endocrinology, Diabetes, and Metabolism)
Source: Pediatric Endocrinology, Diabetes, and Metabolism - September 20, 2023 Category: Endocrinology Authors: Agnieszka Kozio ł-Kozakowska Ma łgorzata Wójcik Dominika Janu ś Jerzy Starzyk Source Type: research
Lipid metabolism and renal function markers in obese adolescents
CONCLUSIONS: Renal function of the obese adolescents included in the study was normal and the associations with lipid metabolism were poorly expressed.PMID:37728460 | PMC:PMC10411080 | DOI:10.5114/pedm.2023.125612 (Source: Pediatric Endocrinology, Diabetes, and Metabolism)
Source: Pediatric Endocrinology, Diabetes, and Metabolism - September 20, 2023 Category: Endocrinology Authors: Aleksandra Radosz Anna Obuchowicz Source Type: research
Subclinical hypothyroidism in children and adolescents as mild dysfunction of the thyroid gland: a single-center study
Pediatr Endocrinol Diabetes Metab. 2023;29(2):97-103. doi: 10.5114/pedm.2023.124266.ABSTRACTINTRODUCTION: Subclinical hypothyroidism (SH) is a biochemical diagnosis made when a serum thyroid-stimulating hormone (TSH) is ele-vated with circulating thyroid hormone levels within their reference ranges.AIM OF THE STUDY: Aim of our prospective non-randomized study was to evaluate the course of SH.MATERIAL AND METHODS: All patients with suspicion of SH referred to the Endocrinology Outpatient Clinic between 2014 and 2018 were recruited to prospective study.RESULTS: A total of 130 patients with SH were recruited for this study. T...
Source: Pediatric Endocrinology, Diabetes, and Metabolism - September 20, 2023 Category: Endocrinology Authors: Kamila Szeliga Aleksandra Antosz Karolina Skrzynska Barbara Kalina-Faska Aneta Gawlik Source Type: research
"The obesity pandemic" in the COVID-19 pandemic - new treatment for an old problem
This article provides a review of the literature on the recent worsening of obesity in the paediatric population, with particular emphasis on the importance of the COVID-19 pandemic. New methods of fighting obesity with the use of telemedicine and current methods of pharmacotherapy, including new drugs, are presented.PMID:37728462 | PMC:PMC10411083 | DOI:10.5114/pedm.2023.129342 (Source: Pediatric Endocrinology, Diabetes, and Metabolism)
Source: Pediatric Endocrinology, Diabetes, and Metabolism - September 20, 2023 Category: Endocrinology Authors: Kalina Fabin-Czepiel Karolina Pieczy ńska-Chapuła Gra żyna Deja Source Type: research
Premature pubarche during minipuberty - literature review and two case reports
CONCLUSIONS: Isolated pubic hair in infancy as a mild, self-limiting variant of precocious puberty in infants should be a diagnosis of exclusion. The condition resolves spontaneously, but it absolutely requires further follow-up to exclude serious aetiology in the case of puberty progression.PMID:37728463 | PMC:PMC10411085 | DOI:10.5114/pedm.2023.129343 (Source: Pediatric Endocrinology, Diabetes, and Metabolism)
Source: Pediatric Endocrinology, Diabetes, and Metabolism - September 20, 2023 Category: Endocrinology Authors: Anna Raku ś-Kwiatosz El żbieta Budzyńska Iwona Be ń-Skowronek Source Type: research
Novel homozygous leptin receptor mutation in an infant with monogenic obesity
We report the case of a 12-month-old male infant born of a non-consanguineous marriage. He presented to us with rapid weight gain from 2 months of age along with hyperphagia. Biochemistry revealed a deranged lipid profile, elevated transaminases, and markedly raised serum leptin levels. On genetic analysis, a novel mutation was detected, which was a homozygous variation In exon 12 of the LEPR gene (chr1:g.65608901G>A) that resulted in the synonymous amino acid change of lysine at codon 584 proximal to donor splice site (p.Lys584). The in silico prediction of the variant was 'damaging' by MutationTaster2. The mutation wa...
Source: Pediatric Endocrinology, Diabetes, and Metabolism - September 20, 2023 Category: Endocrinology Authors: Hiya Boro Vikash Bundela Velmurugan Mannar Lakshmi Nagendra Vinita Jain Bimal Jain Senthil Kumar Sourabh Agstam Source Type: research
Potential bacteriophages to overcome bacterial infection of Alcaligenes faecalis in diabetic ulcer
CONCLUSIONS: The 6 isolates that were isolated had the ability to infect by forming a prophage that could inhibit the growth of Alcaligenes faecalis and other pathogenic bacteria in diabetic ulcers.PMID:37728456 | PMC:PMC10411081 | DOI:10.5114/pedm.2023.125363 (Source: Pediatric Endocrinology, Diabetes, and Metabolism)
Source: Pediatric Endocrinology, Diabetes, and Metabolism - September 20, 2023 Category: Endocrinology Authors: Erlia Narulita Vivi Indah Nur Cahyati Riska A Febrianti Mochammad Iqbal Source Type: research
Assessment of fibroblast growth factor 21 in children with type 1 diabetes mellitus in relation to microvascular complications
CONCLUSIONS: FGF21 is significantly higher among children with DM1 than in controls. However, its role in diabetic microvascular complica-tions needs further assessment.PMID:37728457 | PMC:PMC10411091 | DOI:10.5114/pedm.2022.121372 (Source: Pediatric Endocrinology, Diabetes, and Metabolism)
Source: Pediatric Endocrinology, Diabetes, and Metabolism - September 20, 2023 Category: Endocrinology Authors: Nermien Tantawy Eman Sherif Randa M Matter Nouran Salah Nour Eldin Abozeid Heba Atif Source Type: research
Are menstrual disorders in adolescent girls related to metabolic disorders?
CONCLUSIONS: Adolescent girls with menstrual disorders are insulin resistant, regardless of PCOS diagnosis. The severity of menstrual disorders may be related to the incidence of lipid disorders in adolescent girls.PMID:37728458 | PMC:PMC10411084 | DOI:10.5114/pedm.2023.125364 (Source: Pediatric Endocrinology, Diabetes, and Metabolism)
Source: Pediatric Endocrinology, Diabetes, and Metabolism - September 20, 2023 Category: Endocrinology Authors: El żbieta Foryś Adrianna Baran Aleksandra Dziurdzia Ewelina Jarosz-W ójcik Pawe ł Matusik Aneta Gawlik Ryszard Tomaszewski Agnieszka Zachurzok Source Type: research
The positive impact of lifestyle intervention on selected mio- and chemokines levels in prepubertal children with obesity
CONCLUSIONS: Personalized diet modification and regular, daily exercises may positively influence on the levels of irisin and chemerin.PMID:37728459 | PMC:PMC10411087 | DOI:10.5114/pedm.2023.127273 (Source: Pediatric Endocrinology, Diabetes, and Metabolism)
Source: Pediatric Endocrinology, Diabetes, and Metabolism - September 20, 2023 Category: Endocrinology Authors: Agnieszka Kozio ł-Kozakowska Ma łgorzata Wójcik Dominika Janu ś Jerzy Starzyk Source Type: research
Lipid metabolism and renal function markers in obese adolescents
CONCLUSIONS: Renal function of the obese adolescents included in the study was normal and the associations with lipid metabolism were poorly expressed.PMID:37728460 | PMC:PMC10411080 | DOI:10.5114/pedm.2023.125612 (Source: Pediatric Endocrinology, Diabetes, and Metabolism)
Source: Pediatric Endocrinology, Diabetes, and Metabolism - September 20, 2023 Category: Endocrinology Authors: Aleksandra Radosz Anna Obuchowicz Source Type: research
Subclinical hypothyroidism in children and adolescents as mild dysfunction of the thyroid gland: a single-center study
Pediatr Endocrinol Diabetes Metab. 2023;29(2):97-103. doi: 10.5114/pedm.2023.124266.ABSTRACTINTRODUCTION: Subclinical hypothyroidism (SH) is a biochemical diagnosis made when a serum thyroid-stimulating hormone (TSH) is ele-vated with circulating thyroid hormone levels within their reference ranges.AIM OF THE STUDY: Aim of our prospective non-randomized study was to evaluate the course of SH.MATERIAL AND METHODS: All patients with suspicion of SH referred to the Endocrinology Outpatient Clinic between 2014 and 2018 were recruited to prospective study.RESULTS: A total of 130 patients with SH were recruited for this study. T...
Source: Pediatric Endocrinology, Diabetes, and Metabolism - September 20, 2023 Category: Endocrinology Authors: Kamila Szeliga Aleksandra Antosz Karolina Skrzynska Barbara Kalina-Faska Aneta Gawlik Source Type: research