Endocrine disorders in a patient with a suspicion of a mitochondrial disease, MELAS syndrome - a case report and literature review
We present a girl who was suspected of MELAS syndrome during the diagnostic evaluation of short stature. The patient suffered from symptoms potentially indicating mitochondrial disease, such as muscular weakness, cranial nerve VI palsy, headaches, retinitis pigmentosa, sensory-neural hearing loss, and elevated lactic acid. T2-weighted brain MRI showed hyperintense lesions in the white matter. Muscular biopsy revealed ragged red fibres. Genetic evaluation did not detect the most common mutations in the MT-TL1 gene and MT-ND5 gene. Endocrine tests led to the confirmation of growth hormone deficiency, and so replacement treat...
Source: Pediatric Endocrinology, Diabetes, and Metabolism - October 1, 2021 Category: Endocrinology Authors: Marta Baszy ńska-Wilk El żbieta Moszczyńska Maria Szarras-Czapnik Marta Wysocka-Mincewicz Urszula W ątrobińska Agata Koz łowska Mieczys ław Szalecki Source Type: research

Continuous glucose monitoring systems in well-controlled children with type 1 diabetes mellitus
Pediatr Endocrinol Diabetes Metab. 2021 Oct 1:44673. doi: 10.5114/pedm.2021.107717. Online ahead of print.ABSTRACTINTRODUCTION: Numerous studies have demonstrated the clinical benefits of using continuous glucose monitoring (CGM) systems among patients with type 1 diabetes (T1D). Aim of the study was to assess the effectiveness of CGM on metabolic control in children with T1D and well-controlled disease prior to the study.MATERIAL AND METHODS: This prospective analysis included 99 children (46 girls) at the median age of 11.23 years and diabetes duration of at least 1 year (median: 5.16 years), generally well controlled me...
Source: Pediatric Endocrinology, Diabetes, and Metabolism - October 1, 2021 Category: Endocrinology Authors: Emilia M Kowalczyk Marta Adamczyk Justyna Pietrzyk Barbara Jastrz ębska Agnieszka Szypowska Source Type: research

Endocrine disorders in a patient with a suspicion of a mitochondrial disease, MELAS syndrome - a case report and literature review
We present a girl who was suspected of MELAS syndrome during the diagnostic evaluation of short stature. The patient suffered from symptoms potentially indicating mitochondrial disease, such as muscular weakness, cranial nerve VI palsy, headaches, retinitis pigmentosa, sensory-neural hearing loss, and elevated lactic acid. T2-weighted brain MRI showed hyperintense lesions in the white matter. Muscular biopsy revealed ragged red fibres. Genetic evaluation did not detect the most common mutations in the MT-TL1 gene and MT-ND5 gene. Endocrine tests led to the confirmation of growth hormone deficiency, and so replacement treat...
Source: Pediatric Endocrinology, Diabetes, and Metabolism - October 1, 2021 Category: Endocrinology Authors: Marta Baszy ńska-Wilk El żbieta Moszczyńska Maria Szarras-Czapnik Marta Wysocka-Mincewicz Urszula W ątrobińska Agata Koz łowska Mieczys ław Szalecki Source Type: research

Continuous glucose monitoring systems in well-controlled children with type 1 diabetes mellitus
Pediatr Endocrinol Diabetes Metab. 2021 Oct 1:44673. doi: 10.5114/pedm.2021.107717. Online ahead of print.ABSTRACTINTRODUCTION: Numerous studies have demonstrated the clinical benefits of using continuous glucose monitoring (CGM) systems among patients with type 1 diabetes (T1D). Aim of the study was to assess the effectiveness of CGM on metabolic control in children with T1D and well-controlled disease prior to the study.MATERIAL AND METHODS: This prospective analysis included 99 children (46 girls) at the median age of 11.23 years and diabetes duration of at least 1 year (median: 5.16 years), generally well controlled me...
Source: Pediatric Endocrinology, Diabetes, and Metabolism - October 1, 2021 Category: Endocrinology Authors: Emilia M Kowalczyk Marta Adamczyk Justyna Pietrzyk Barbara Jastrz ębska Agnieszka Szypowska Source Type: research

Endocrine disorders in a patient with a suspicion of a mitochondrial disease, MELAS syndrome - a case report and literature review
We present a girl who was suspected of MELAS syndrome during the diagnostic evaluation of short stature. The patient suffered from symptoms potentially indicating mitochondrial disease, such as muscular weakness, cranial nerve VI palsy, headaches, retinitis pigmentosa, sensory-neural hearing loss, and elevated lactic acid. T2-weighted brain MRI showed hyperintense lesions in the white matter. Muscular biopsy revealed ragged red fibres. Genetic evaluation did not detect the most common mutations in the MT-TL1 gene and MT-ND5 gene. Endocrine tests led to the confirmation of growth hormone deficiency, and so replacement treat...
Source: Pediatric Endocrinology, Diabetes, and Metabolism - October 1, 2021 Category: Endocrinology Authors: Marta Baszy ńska-Wilk El żbieta Moszczyńska Maria Szarras-Czapnik Marta Wysocka-Mincewicz Urszula W ątrobińska Agata Koz łowska Mieczys ław Szalecki Source Type: research

Continuous glucose monitoring systems in well-controlled children with type 1 diabetes mellitus
Pediatr Endocrinol Diabetes Metab. 2021 Oct 1:44673. doi: 10.5114/pedm.2021.107717. Online ahead of print.ABSTRACTINTRODUCTION: Numerous studies have demonstrated the clinical benefits of using continuous glucose monitoring (CGM) systems among patients with type 1 diabetes (T1D). Aim of the study was to assess the effectiveness of CGM on metabolic control in children with T1D and well-controlled disease prior to the study.MATERIAL AND METHODS: This prospective analysis included 99 children (46 girls) at the median age of 11.23 years and diabetes duration of at least 1 year (median: 5.16 years), generally well controlled me...
Source: Pediatric Endocrinology, Diabetes, and Metabolism - October 1, 2021 Category: Endocrinology Authors: Emilia M Kowalczyk Marta Adamczyk Justyna Pietrzyk Barbara Jastrz ębska Agnieszka Szypowska Source Type: research

Endocrine disorders in a patient with a suspicion of a mitochondrial disease, MELAS syndrome - a case report and literature review
We present a girl who was suspected of MELAS syndrome during the diagnostic evaluation of short stature. The patient suffered from symptoms potentially indicating mitochondrial disease, such as muscular weakness, cranial nerve VI palsy, headaches, retinitis pigmentosa, sensory-neural hearing loss, and elevated lactic acid. T2-weighted brain MRI showed hyperintense lesions in the white matter. Muscular biopsy revealed ragged red fibres. Genetic evaluation did not detect the most common mutations in the MT-TL1 gene and MT-ND5 gene. Endocrine tests led to the confirmation of growth hormone deficiency, and so replacement treat...
Source: Pediatric Endocrinology, Diabetes, and Metabolism - October 1, 2021 Category: Endocrinology Authors: Marta Baszy ńska-Wilk El żbieta Moszczyńska Maria Szarras-Czapnik Marta Wysocka-Mincewicz Urszula W ątrobińska Agata Koz łowska Mieczys ław Szalecki Source Type: research

Continuous glucose monitoring systems in well-controlled children with type 1 diabetes mellitus
Pediatr Endocrinol Diabetes Metab. 2021 Oct 1:44673. doi: 10.5114/pedm.2021.107717. Online ahead of print.ABSTRACTINTRODUCTION: Numerous studies have demonstrated the clinical benefits of using continuous glucose monitoring (CGM) systems among patients with type 1 diabetes (T1D). Aim of the study was to assess the effectiveness of CGM on metabolic control in children with T1D and well-controlled disease prior to the study.MATERIAL AND METHODS: This prospective analysis included 99 children (46 girls) at the median age of 11.23 years and diabetes duration of at least 1 year (median: 5.16 years), generally well controlled me...
Source: Pediatric Endocrinology, Diabetes, and Metabolism - October 1, 2021 Category: Endocrinology Authors: Emilia M Kowalczyk Marta Adamczyk Justyna Pietrzyk Barbara Jastrz ębska Agnieszka Szypowska Source Type: research

Endocrine disorders in a patient with a suspicion of a mitochondrial disease, MELAS syndrome - a case report and literature review
We present a girl who was suspected of MELAS syndrome during the diagnostic evaluation of short stature. The patient suffered from symptoms potentially indicating mitochondrial disease, such as muscular weakness, cranial nerve VI palsy, headaches, retinitis pigmentosa, sensory-neural hearing loss, and elevated lactic acid. T2-weighted brain MRI showed hyperintense lesions in the white matter. Muscular biopsy revealed ragged red fibres. Genetic evaluation did not detect the most common mutations in the MT-TL1 gene and MT-ND5 gene. Endocrine tests led to the confirmation of growth hormone deficiency, and so replacement treat...
Source: Pediatric Endocrinology, Diabetes, and Metabolism - October 1, 2021 Category: Endocrinology Authors: Marta Baszy ńska-Wilk El żbieta Moszczyńska Maria Szarras-Czapnik Marta Wysocka-Mincewicz Urszula W ątrobińska Agata Koz łowska Mieczys ław Szalecki Source Type: research

Continuous glucose monitoring systems in well-controlled children with type 1 diabetes mellitus
Pediatr Endocrinol Diabetes Metab. 2021 Oct 1:44673. doi: 10.5114/pedm.2021.107717. Online ahead of print.ABSTRACTINTRODUCTION: Numerous studies have demonstrated the clinical benefits of using continuous glucose monitoring (CGM) systems among patients with type 1 diabetes (T1D). Aim of the study was to assess the effectiveness of CGM on metabolic control in children with T1D and well-controlled disease prior to the study.MATERIAL AND METHODS: This prospective analysis included 99 children (46 girls) at the median age of 11.23 years and diabetes duration of at least 1 year (median: 5.16 years), generally well controlled me...
Source: Pediatric Endocrinology, Diabetes, and Metabolism - October 1, 2021 Category: Endocrinology Authors: Emilia M Kowalczyk Marta Adamczyk Justyna Pietrzyk Barbara Jastrz ębska Agnieszka Szypowska Source Type: research

Endocrine disorders in a patient with a suspicion of a mitochondrial disease, MELAS syndrome - a case report and literature review
We present a girl who was suspected of MELAS syndrome during the diagnostic evaluation of short stature. The patient suffered from symptoms potentially indicating mitochondrial disease, such as muscular weakness, cranial nerve VI palsy, headaches, retinitis pigmentosa, sensory-neural hearing loss, and elevated lactic acid. T2-weighted brain MRI showed hyperintense lesions in the white matter. Muscular biopsy revealed ragged red fibres. Genetic evaluation did not detect the most common mutations in the MT-TL1 gene and MT-ND5 gene. Endocrine tests led to the confirmation of growth hormone deficiency, and so replacement treat...
Source: Pediatric Endocrinology, Diabetes, and Metabolism - October 1, 2021 Category: Endocrinology Authors: Marta Baszy ńska-Wilk El żbieta Moszczyńska Maria Szarras-Czapnik Marta Wysocka-Mincewicz Urszula W ątrobińska Agata Koz łowska Mieczys ław Szalecki Source Type: research

Continuous glucose monitoring systems in well-controlled children with type 1 diabetes mellitus
Pediatr Endocrinol Diabetes Metab. 2021 Oct 1:44673. doi: 10.5114/pedm.2021.107717. Online ahead of print.ABSTRACTINTRODUCTION: Numerous studies have demonstrated the clinical benefits of using continuous glucose monitoring (CGM) systems among patients with type 1 diabetes (T1D). Aim of the study was to assess the effectiveness of CGM on metabolic control in children with T1D and well-controlled disease prior to the study.MATERIAL AND METHODS: This prospective analysis included 99 children (46 girls) at the median age of 11.23 years and diabetes duration of at least 1 year (median: 5.16 years), generally well controlled me...
Source: Pediatric Endocrinology, Diabetes, and Metabolism - October 1, 2021 Category: Endocrinology Authors: Emilia M Kowalczyk Marta Adamczyk Justyna Pietrzyk Barbara Jastrz ębska Agnieszka Szypowska Source Type: research

Endocrine disorders in a patient with a suspicion of a mitochondrial disease, MELAS syndrome - a case report and literature review
We present a girl who was suspected of MELAS syndrome during the diagnostic evaluation of short stature. The patient suffered from symptoms potentially indicating mitochondrial disease, such as muscular weakness, cranial nerve VI palsy, headaches, retinitis pigmentosa, sensory-neural hearing loss, and elevated lactic acid. T2-weighted brain MRI showed hyperintense lesions in the white matter. Muscular biopsy revealed ragged red fibres. Genetic evaluation did not detect the most common mutations in the MT-TL1 gene and MT-ND5 gene. Endocrine tests led to the confirmation of growth hormone deficiency, and so replacement treat...
Source: Pediatric Endocrinology, Diabetes, and Metabolism - October 1, 2021 Category: Endocrinology Authors: Marta Baszy ńska-Wilk El żbieta Moszczyńska Maria Szarras-Czapnik Marta Wysocka-Mincewicz Urszula W ątrobińska Agata Koz łowska Mieczys ław Szalecki Source Type: research

Continuous glucose monitoring systems in well-controlled children with type 1 diabetes mellitus
Pediatr Endocrinol Diabetes Metab. 2021 Oct 1:44673. doi: 10.5114/pedm.2021.107717. Online ahead of print.ABSTRACTINTRODUCTION: Numerous studies have demonstrated the clinical benefits of using continuous glucose monitoring (CGM) systems among patients with type 1 diabetes (T1D). Aim of the study was to assess the effectiveness of CGM on metabolic control in children with T1D and well-controlled disease prior to the study.MATERIAL AND METHODS: This prospective analysis included 99 children (46 girls) at the median age of 11.23 years and diabetes duration of at least 1 year (median: 5.16 years), generally well controlled me...
Source: Pediatric Endocrinology, Diabetes, and Metabolism - October 1, 2021 Category: Endocrinology Authors: Emilia M Kowalczyk Marta Adamczyk Justyna Pietrzyk Barbara Jastrz ębska Agnieszka Szypowska Source Type: research

Endocrine disorders in a patient with a suspicion of a mitochondrial disease, MELAS syndrome - a case report and literature review
We present a girl who was suspected of MELAS syndrome during the diagnostic evaluation of short stature. The patient suffered from symptoms potentially indicating mitochondrial disease, such as muscular weakness, cranial nerve VI palsy, headaches, retinitis pigmentosa, sensory-neural hearing loss, and elevated lactic acid. T2-weighted brain MRI showed hyperintense lesions in the white matter. Muscular biopsy revealed ragged red fibres. Genetic evaluation did not detect the most common mutations in the MT-TL1 gene and MT-ND5 gene. Endocrine tests led to the confirmation of growth hormone deficiency, and so replacement treat...
Source: Pediatric Endocrinology, Diabetes, and Metabolism - October 1, 2021 Category: Endocrinology Authors: Marta Baszy ńska-Wilk El żbieta Moszczyńska Maria Szarras-Czapnik Marta Wysocka-Mincewicz Urszula W ątrobińska Agata Koz łowska Mieczys ław Szalecki Source Type: research

Continuous glucose monitoring systems in well-controlled children with type 1 diabetes mellitus
Pediatr Endocrinol Diabetes Metab. 2021 Oct 1:44673. doi: 10.5114/pedm.2021.107717. Online ahead of print.ABSTRACTINTRODUCTION: Numerous studies have demonstrated the clinical benefits of using continuous glucose monitoring (CGM) systems among patients with type 1 diabetes (T1D). Aim of the study was to assess the effectiveness of CGM on metabolic control in children with T1D and well-controlled disease prior to the study.MATERIAL AND METHODS: This prospective analysis included 99 children (46 girls) at the median age of 11.23 years and diabetes duration of at least 1 year (median: 5.16 years), generally well controlled me...
Source: Pediatric Endocrinology, Diabetes, and Metabolism - October 1, 2021 Category: Endocrinology Authors: Emilia M Kowalczyk Marta Adamczyk Justyna Pietrzyk Barbara Jastrz ębska Agnieszka Szypowska Source Type: research

Endocrine disorders in a patient with a suspicion of a mitochondrial disease, MELAS syndrome - a case report and literature review
We present a girl who was suspected of MELAS syndrome during the diagnostic evaluation of short stature. The patient suffered from symptoms potentially indicating mitochondrial disease, such as muscular weakness, cranial nerve VI palsy, headaches, retinitis pigmentosa, sensory-neural hearing loss, and elevated lactic acid. T2-weighted brain MRI showed hyperintense lesions in the white matter. Muscular biopsy revealed ragged red fibres. Genetic evaluation did not detect the most common mutations in the MT-TL1 gene and MT-ND5 gene. Endocrine tests led to the confirmation of growth hormone deficiency, and so replacement treat...
Source: Pediatric Endocrinology, Diabetes, and Metabolism - October 1, 2021 Category: Endocrinology Authors: Marta Baszy ńska-Wilk El żbieta Moszczyńska Maria Szarras-Czapnik Marta Wysocka-Mincewicz Urszula W ątrobińska Agata Koz łowska Mieczys ław Szalecki Source Type: research

Continuous glucose monitoring systems in well-controlled children with type 1 diabetes mellitus
Pediatr Endocrinol Diabetes Metab. 2021 Oct 1:44673. doi: 10.5114/pedm.2021.107717. Online ahead of print.ABSTRACTINTRODUCTION: Numerous studies have demonstrated the clinical benefits of using continuous glucose monitoring (CGM) systems among patients with type 1 diabetes (T1D). Aim of the study was to assess the effectiveness of CGM on metabolic control in children with T1D and well-controlled disease prior to the study.MATERIAL AND METHODS: This prospective analysis included 99 children (46 girls) at the median age of 11.23 years and diabetes duration of at least 1 year (median: 5.16 years), generally well controlled me...
Source: Pediatric Endocrinology, Diabetes, and Metabolism - October 1, 2021 Category: Endocrinology Authors: Emilia M Kowalczyk Marta Adamczyk Justyna Pietrzyk Barbara Jastrz ębska Agnieszka Szypowska Source Type: research

Endocrine disorders in a patient with a suspicion of a mitochondrial disease, MELAS syndrome - a case report and literature review
We present a girl who was suspected of MELAS syndrome during the diagnostic evaluation of short stature. The patient suffered from symptoms potentially indicating mitochondrial disease, such as muscular weakness, cranial nerve VI palsy, headaches, retinitis pigmentosa, sensory-neural hearing loss, and elevated lactic acid. T2-weighted brain MRI showed hyperintense lesions in the white matter. Muscular biopsy revealed ragged red fibres. Genetic evaluation did not detect the most common mutations in the MT-TL1 gene and MT-ND5 gene. Endocrine tests led to the confirmation of growth hormone deficiency, and so replacement treat...
Source: Pediatric Endocrinology, Diabetes, and Metabolism - October 1, 2021 Category: Endocrinology Authors: Marta Baszy ńska-Wilk El żbieta Moszczyńska Maria Szarras-Czapnik Marta Wysocka-Mincewicz Urszula W ątrobińska Agata Koz łowska Mieczys ław Szalecki Source Type: research

Continuous glucose monitoring systems in well-controlled children with type 1 diabetes mellitus
Pediatr Endocrinol Diabetes Metab. 2021 Oct 1:44673. doi: 10.5114/pedm.2021.107717. Online ahead of print.ABSTRACTINTRODUCTION: Numerous studies have demonstrated the clinical benefits of using continuous glucose monitoring (CGM) systems among patients with type 1 diabetes (T1D). Aim of the study was to assess the effectiveness of CGM on metabolic control in children with T1D and well-controlled disease prior to the study.MATERIAL AND METHODS: This prospective analysis included 99 children (46 girls) at the median age of 11.23 years and diabetes duration of at least 1 year (median: 5.16 years), generally well controlled me...
Source: Pediatric Endocrinology, Diabetes, and Metabolism - October 1, 2021 Category: Endocrinology Authors: Emilia M Kowalczyk Marta Adamczyk Justyna Pietrzyk Barbara Jastrz ębska Agnieszka Szypowska Source Type: research

Endocrine disorders in a patient with a suspicion of a mitochondrial disease, MELAS syndrome - a case report and literature review
We present a girl who was suspected of MELAS syndrome during the diagnostic evaluation of short stature. The patient suffered from symptoms potentially indicating mitochondrial disease, such as muscular weakness, cranial nerve VI palsy, headaches, retinitis pigmentosa, sensory-neural hearing loss, and elevated lactic acid. T2-weighted brain MRI showed hyperintense lesions in the white matter. Muscular biopsy revealed ragged red fibres. Genetic evaluation did not detect the most common mutations in the MT-TL1 gene and MT-ND5 gene. Endocrine tests led to the confirmation of growth hormone deficiency, and so replacement treat...
Source: Pediatric Endocrinology, Diabetes, and Metabolism - October 1, 2021 Category: Endocrinology Authors: Marta Baszy ńska-Wilk El żbieta Moszczyńska Maria Szarras-Czapnik Marta Wysocka-Mincewicz Urszula W ątrobińska Agata Koz łowska Mieczys ław Szalecki Source Type: research

Continuous glucose monitoring systems in well-controlled children with type 1 diabetes mellitus
Pediatr Endocrinol Diabetes Metab. 2021 Oct 1:44673. doi: 10.5114/pedm.2021.107717. Online ahead of print.ABSTRACTINTRODUCTION: Numerous studies have demonstrated the clinical benefits of using continuous glucose monitoring (CGM) systems among patients with type 1 diabetes (T1D). Aim of the study was to assess the effectiveness of CGM on metabolic control in children with T1D and well-controlled disease prior to the study.MATERIAL AND METHODS: This prospective analysis included 99 children (46 girls) at the median age of 11.23 years and diabetes duration of at least 1 year (median: 5.16 years), generally well controlled me...
Source: Pediatric Endocrinology, Diabetes, and Metabolism - October 1, 2021 Category: Endocrinology Authors: Emilia M Kowalczyk Marta Adamczyk Justyna Pietrzyk Barbara Jastrz ębska Agnieszka Szypowska Source Type: research

Endocrine disorders in a patient with a suspicion of a mitochondrial disease, MELAS syndrome - a case report and literature review
We present a girl who was suspected of MELAS syndrome during the diagnostic evaluation of short stature. The patient suffered from symptoms potentially indicating mitochondrial disease, such as muscular weakness, cranial nerve VI palsy, headaches, retinitis pigmentosa, sensory-neural hearing loss, and elevated lactic acid. T2-weighted brain MRI showed hyperintense lesions in the white matter. Muscular biopsy revealed ragged red fibres. Genetic evaluation did not detect the most common mutations in the MT-TL1 gene and MT-ND5 gene. Endocrine tests led to the confirmation of growth hormone deficiency, and so replacement treat...
Source: Pediatric Endocrinology, Diabetes, and Metabolism - October 1, 2021 Category: Endocrinology Authors: Marta Baszy ńska-Wilk El żbieta Moszczyńska Maria Szarras-Czapnik Marta Wysocka-Mincewicz Urszula W ątrobińska Agata Koz łowska Mieczys ław Szalecki Source Type: research

Continuous glucose monitoring systems in well-controlled children with type 1 diabetes mellitus
Pediatr Endocrinol Diabetes Metab. 2021 Oct 1:44673. doi: 10.5114/pedm.2021.107717. Online ahead of print.ABSTRACTINTRODUCTION: Numerous studies have demonstrated the clinical benefits of using continuous glucose monitoring (CGM) systems among patients with type 1 diabetes (T1D). Aim of the study was to assess the effectiveness of CGM on metabolic control in children with T1D and well-controlled disease prior to the study.MATERIAL AND METHODS: This prospective analysis included 99 children (46 girls) at the median age of 11.23 years and diabetes duration of at least 1 year (median: 5.16 years), generally well controlled me...
Source: Pediatric Endocrinology, Diabetes, and Metabolism - October 1, 2021 Category: Endocrinology Authors: Emilia M Kowalczyk Marta Adamczyk Justyna Pietrzyk Barbara Jastrz ębska Agnieszka Szypowska Source Type: research

Endocrine disorders in a patient with a suspicion of a mitochondrial disease, MELAS syndrome - a case report and literature review
We present a girl who was suspected of MELAS syndrome during the diagnostic evaluation of short stature. The patient suffered from symptoms potentially indicating mitochondrial disease, such as muscular weakness, cranial nerve VI palsy, headaches, retinitis pigmentosa, sensory-neural hearing loss, and elevated lactic acid. T2-weighted brain MRI showed hyperintense lesions in the white matter. Muscular biopsy revealed ragged red fibres. Genetic evaluation did not detect the most common mutations in the MT-TL1 gene and MT-ND5 gene. Endocrine tests led to the confirmation of growth hormone deficiency, and so replacement treat...
Source: Pediatric Endocrinology, Diabetes, and Metabolism - October 1, 2021 Category: Endocrinology Authors: Marta Baszy ńska-Wilk El żbieta Moszczyńska Maria Szarras-Czapnik Marta Wysocka-Mincewicz Urszula W ątrobińska Agata Koz łowska Mieczys ław Szalecki Source Type: research

Continuous glucose monitoring systems in well-controlled children with type 1 diabetes mellitus
Pediatr Endocrinol Diabetes Metab. 2021 Oct 1:44673. doi: 10.5114/pedm.2021.107717. Online ahead of print.ABSTRACTINTRODUCTION: Numerous studies have demonstrated the clinical benefits of using continuous glucose monitoring (CGM) systems among patients with type 1 diabetes (T1D). Aim of the study was to assess the effectiveness of CGM on metabolic control in children with T1D and well-controlled disease prior to the study.MATERIAL AND METHODS: This prospective analysis included 99 children (46 girls) at the median age of 11.23 years and diabetes duration of at least 1 year (median: 5.16 years), generally well controlled me...
Source: Pediatric Endocrinology, Diabetes, and Metabolism - October 1, 2021 Category: Endocrinology Authors: Emilia M Kowalczyk Marta Adamczyk Justyna Pietrzyk Barbara Jastrz ębska Agnieszka Szypowska Source Type: research

Endocrine disorders in a patient with a suspicion of a mitochondrial disease, MELAS syndrome - a case report and literature review
We present a girl who was suspected of MELAS syndrome during the diagnostic evaluation of short stature. The patient suffered from symptoms potentially indicating mitochondrial disease, such as muscular weakness, cranial nerve VI palsy, headaches, retinitis pigmentosa, sensory-neural hearing loss, and elevated lactic acid. T2-weighted brain MRI showed hyperintense lesions in the white matter. Muscular biopsy revealed ragged red fibres. Genetic evaluation did not detect the most common mutations in the MT-TL1 gene and MT-ND5 gene. Endocrine tests led to the confirmation of growth hormone deficiency, and so replacement treat...
Source: Pediatric Endocrinology, Diabetes, and Metabolism - October 1, 2021 Category: Endocrinology Authors: Marta Baszy ńska-Wilk El żbieta Moszczyńska Maria Szarras-Czapnik Marta Wysocka-Mincewicz Urszula W ątrobińska Agata Koz łowska Mieczys ław Szalecki Source Type: research

Continuous glucose monitoring systems in well-controlled children with type 1 diabetes mellitus
Pediatr Endocrinol Diabetes Metab. 2021 Oct 1:44673. doi: 10.5114/pedm.2021.107717. Online ahead of print.ABSTRACTINTRODUCTION: Numerous studies have demonstrated the clinical benefits of using continuous glucose monitoring (CGM) systems among patients with type 1 diabetes (T1D). Aim of the study was to assess the effectiveness of CGM on metabolic control in children with T1D and well-controlled disease prior to the study.MATERIAL AND METHODS: This prospective analysis included 99 children (46 girls) at the median age of 11.23 years and diabetes duration of at least 1 year (median: 5.16 years), generally well controlled me...
Source: Pediatric Endocrinology, Diabetes, and Metabolism - October 1, 2021 Category: Endocrinology Authors: Emilia M Kowalczyk Marta Adamczyk Justyna Pietrzyk Barbara Jastrz ębska Agnieszka Szypowska Source Type: research

In memoriam of Professor Leszek Szewczyk
Pediatr Endocrinol Diabetes Metab. 2021;27(2):69. doi: 10.5114/pedm.2021.107161.NO ABSTRACTPMID:34514763 | DOI:10.5114/pedm.2021.107161 (Source: Pediatric Endocrinology, Diabetes, and Metabolism)
Source: Pediatric Endocrinology, Diabetes, and Metabolism - September 13, 2021 Category: Endocrinology Authors: Iwona Be ń-Skowronek Source Type: research

A multi-disciplinary approach to weight management of school-age girls: a study protocol
This study aimed to evaluate the effect of a combination program including smart-phone nutrition education, physical activity, and cognitive behavioral therapy (CBT) programs in the management of obesity and overweight among elementary school girls in comparison with a traditional education method.MATERIAL AND METHODS: The primary outcome of this study is the assessment of changes in anthropometric data after 10 weeks. The secondary outcome is investigating the effect of treatment on biochemical data. Sixty-two elementary school girls aged 9-12 years with the body mass index (BMI) for age above 85th percentile will be chos...
Source: Pediatric Endocrinology, Diabetes, and Metabolism - September 13, 2021 Category: Endocrinology Authors: Sara Salahshornezhad Zahra Sohrabi Saeid Doaei Maryam Gholamalizadeh Arash Mani Manoosh Mehrabi Morteza Zare Marzieh Akbarzadeh Source Type: research

Congenital hypothyroidism in Indian preterm babies - screening, prevalence, and aetiology
Pediatr Endocrinol Diabetes Metab. 2021;27(2):82-86. doi: 10.5114/pedm.2021.105295.ABSTRACTINTRODUCTION: Paucity of data on hypothyroidism in Indian preterms. Aim of the study: To describe the prevalence, aetiology, and experience with screening for primary hypothyroidism in preterm babies.MATERIAL AND METHODS: A prospective observational study conducted for 3 years in a tertiary care unit, where all babies born
Source: Pediatric Endocrinology, Diabetes, and Metabolism - September 13, 2021 Category: Endocrinology Authors: Hemchand Krishna Prasad Poornima Pulluru Lakshmi Venugopalan Gnanabalan Murugesan Shanmughasundaram Ramanathan Source Type: research

The quality of life in adult patients treated for Cushing's disease in childhood
CONCLUSIONS: During long-term follow-up the QoL of patients after CD treatment in childhood is not significantly different wit QoL of healthy controls. Further studies are needed to expand the knowledge of factors that may contribute to the QoL in CD patients who were treated in childhood.PMID:34514766 | DOI:10.5114/pedm.2021.107163 (Source: Pediatric Endocrinology, Diabetes, and Metabolism)
Source: Pediatric Endocrinology, Diabetes, and Metabolism - September 13, 2021 Category: Endocrinology Authors: Katarzyna Pasternak-Pietrzak El żbieta Moszczyńska Mieczys ław Szalecki Source Type: research

Level of type 1 diabetes education of physiotherapists based on selected factors
CONCLUSIONS: The majority of the respondents had a moderate level of diabetes education. The level of the T1D knowledge of physiotherapists was primarily determined by their number of years on the job. Age and sex of the respondents had no impact on the level of their knowledge of diabetes (T1D).PMID:34514767 | DOI:10.5114/pedm.2021.107164 (Source: Pediatric Endocrinology, Diabetes, and Metabolism)
Source: Pediatric Endocrinology, Diabetes, and Metabolism - September 13, 2021 Category: Endocrinology Authors: Kamil Zaworski Zofia Kubi ńska Source Type: research

C-peptide and residual β-cell function in pediatric diabetes - state of the art
Pediatr Endocrinol Diabetes Metab. 2021;27(2):123-133. doi: 10.5114/pedm.2021.107165.ABSTRACTC-peptide, the molecule produced in an equimolar concentration to insulin, has become an established insulin secretion biomarker in diabetic patients. Measurement of C-peptide level can be helpful in clinical practice for assessing insulin-producing b-cells residual function, especially in the patients who have already started exogenous insulin therapy. Advances in assays have made measurement of C-peptide more reliable and inexpensive. Traditionally, C-peptide is widely used to differentiate between type 1, type 2 and monogenic ty...
Source: Pediatric Endocrinology, Diabetes, and Metabolism - September 13, 2021 Category: Endocrinology Authors: Milena Jamio łkowska-Sztabkowska Barbara G łowińska-Olszewska Artur Bossowski Source Type: research

Metformin - a new approach
Pediatr Endocrinol Diabetes Metab. 2021;27(2):134-140. doi: 10.5114/pedm.2021.107166.ABSTRACTMetformin is a widely used biguanide drug recommended as a first-line antidiabetic for type 2 diabetes. Currently, metformin is used not only in the treatment of diabetes but also in other diseases. Some studies have shown that metformin causes weight loss in insulin-sensitive and insulin-resistant overweight and obese patients. Metformin is an effective and safe option for women with gestational diabetes and type 2 diabetes in pregnancy, and it may also increase the ovulation rate in patients with polycystic ovary syndrome (PCOS)....
Source: Pediatric Endocrinology, Diabetes, and Metabolism - September 13, 2021 Category: Endocrinology Authors: Łucja Cwynar-Zając Source Type: research

In memoriam of Professor Leszek Szewczyk
Pediatr Endocrinol Diabetes Metab. 2021;27(2):69. doi: 10.5114/pedm.2021.107161.NO ABSTRACTPMID:34514763 | DOI:10.5114/pedm.2021.107161 (Source: Pediatric Endocrinology, Diabetes, and Metabolism)
Source: Pediatric Endocrinology, Diabetes, and Metabolism - September 13, 2021 Category: Endocrinology Authors: Iwona Be ń-Skowronek Source Type: research

A multi-disciplinary approach to weight management of school-age girls: a study protocol
This study aimed to evaluate the effect of a combination program including smart-phone nutrition education, physical activity, and cognitive behavioral therapy (CBT) programs in the management of obesity and overweight among elementary school girls in comparison with a traditional education method.MATERIAL AND METHODS: The primary outcome of this study is the assessment of changes in anthropometric data after 10 weeks. The secondary outcome is investigating the effect of treatment on biochemical data. Sixty-two elementary school girls aged 9-12 years with the body mass index (BMI) for age above 85th percentile will be chos...
Source: Pediatric Endocrinology, Diabetes, and Metabolism - September 13, 2021 Category: Endocrinology Authors: Sara Salahshornezhad Zahra Sohrabi Saeid Doaei Maryam Gholamalizadeh Arash Mani Manoosh Mehrabi Morteza Zare Marzieh Akbarzadeh Source Type: research

Congenital hypothyroidism in Indian preterm babies - screening, prevalence, and aetiology
Pediatr Endocrinol Diabetes Metab. 2021;27(2):82-86. doi: 10.5114/pedm.2021.105295.ABSTRACTINTRODUCTION: Paucity of data on hypothyroidism in Indian preterms. Aim of the study: To describe the prevalence, aetiology, and experience with screening for primary hypothyroidism in preterm babies.MATERIAL AND METHODS: A prospective observational study conducted for 3 years in a tertiary care unit, where all babies born
Source: Pediatric Endocrinology, Diabetes, and Metabolism - September 13, 2021 Category: Endocrinology Authors: Hemchand Krishna Prasad Poornima Pulluru Lakshmi Venugopalan Gnanabalan Murugesan Shanmughasundaram Ramanathan Source Type: research

The quality of life in adult patients treated for Cushing's disease in childhood
CONCLUSIONS: During long-term follow-up the QoL of patients after CD treatment in childhood is not significantly different wit QoL of healthy controls. Further studies are needed to expand the knowledge of factors that may contribute to the QoL in CD patients who were treated in childhood.PMID:34514766 | DOI:10.5114/pedm.2021.107163 (Source: Pediatric Endocrinology, Diabetes, and Metabolism)
Source: Pediatric Endocrinology, Diabetes, and Metabolism - September 13, 2021 Category: Endocrinology Authors: Katarzyna Pasternak-Pietrzak El żbieta Moszczyńska Mieczys ław Szalecki Source Type: research

Level of type 1 diabetes education of physiotherapists based on selected factors
CONCLUSIONS: The majority of the respondents had a moderate level of diabetes education. The level of the T1D knowledge of physiotherapists was primarily determined by their number of years on the job. Age and sex of the respondents had no impact on the level of their knowledge of diabetes (T1D).PMID:34514767 | DOI:10.5114/pedm.2021.107164 (Source: Pediatric Endocrinology, Diabetes, and Metabolism)
Source: Pediatric Endocrinology, Diabetes, and Metabolism - September 13, 2021 Category: Endocrinology Authors: Kamil Zaworski Zofia Kubi ńska Source Type: research

C-peptide and residual β-cell function in pediatric diabetes - state of the art
Pediatr Endocrinol Diabetes Metab. 2021;27(2):123-133. doi: 10.5114/pedm.2021.107165.ABSTRACTC-peptide, the molecule produced in an equimolar concentration to insulin, has become an established insulin secretion biomarker in diabetic patients. Measurement of C-peptide level can be helpful in clinical practice for assessing insulin-producing b-cells residual function, especially in the patients who have already started exogenous insulin therapy. Advances in assays have made measurement of C-peptide more reliable and inexpensive. Traditionally, C-peptide is widely used to differentiate between type 1, type 2 and monogenic ty...
Source: Pediatric Endocrinology, Diabetes, and Metabolism - September 13, 2021 Category: Endocrinology Authors: Milena Jamio łkowska-Sztabkowska Barbara G łowińska-Olszewska Artur Bossowski Source Type: research

Metformin - a new approach
Pediatr Endocrinol Diabetes Metab. 2021;27(2):134-140. doi: 10.5114/pedm.2021.107166.ABSTRACTMetformin is a widely used biguanide drug recommended as a first-line antidiabetic for type 2 diabetes. Currently, metformin is used not only in the treatment of diabetes but also in other diseases. Some studies have shown that metformin causes weight loss in insulin-sensitive and insulin-resistant overweight and obese patients. Metformin is an effective and safe option for women with gestational diabetes and type 2 diabetes in pregnancy, and it may also increase the ovulation rate in patients with polycystic ovary syndrome (PCOS)....
Source: Pediatric Endocrinology, Diabetes, and Metabolism - September 13, 2021 Category: Endocrinology Authors: Łucja Cwynar-Zając Source Type: research

In memoriam of Professor Leszek Szewczyk
Pediatr Endocrinol Diabetes Metab. 2021;27(2):69. doi: 10.5114/pedm.2021.107161.NO ABSTRACTPMID:34514763 | DOI:10.5114/pedm.2021.107161 (Source: Pediatric Endocrinology, Diabetes, and Metabolism)
Source: Pediatric Endocrinology, Diabetes, and Metabolism - September 13, 2021 Category: Endocrinology Authors: Iwona Be ń-Skowronek Source Type: research

A multi-disciplinary approach to weight management of school-age girls: a study protocol
This study aimed to evaluate the effect of a combination program including smart-phone nutrition education, physical activity, and cognitive behavioral therapy (CBT) programs in the management of obesity and overweight among elementary school girls in comparison with a traditional education method.MATERIAL AND METHODS: The primary outcome of this study is the assessment of changes in anthropometric data after 10 weeks. The secondary outcome is investigating the effect of treatment on biochemical data. Sixty-two elementary school girls aged 9-12 years with the body mass index (BMI) for age above 85th percentile will be chos...
Source: Pediatric Endocrinology, Diabetes, and Metabolism - September 13, 2021 Category: Endocrinology Authors: Sara Salahshornezhad Zahra Sohrabi Saeid Doaei Maryam Gholamalizadeh Arash Mani Manoosh Mehrabi Morteza Zare Marzieh Akbarzadeh Source Type: research

Congenital hypothyroidism in Indian preterm babies - screening, prevalence, and aetiology
Pediatr Endocrinol Diabetes Metab. 2021;27(2):82-86. doi: 10.5114/pedm.2021.105295.ABSTRACTINTRODUCTION: Paucity of data on hypothyroidism in Indian preterms. Aim of the study: To describe the prevalence, aetiology, and experience with screening for primary hypothyroidism in preterm babies.MATERIAL AND METHODS: A prospective observational study conducted for 3 years in a tertiary care unit, where all babies born
Source: Pediatric Endocrinology, Diabetes, and Metabolism - September 13, 2021 Category: Endocrinology Authors: Hemchand Krishna Prasad Poornima Pulluru Lakshmi Venugopalan Gnanabalan Murugesan Shanmughasundaram Ramanathan Source Type: research

The quality of life in adult patients treated for Cushing's disease in childhood
CONCLUSIONS: During long-term follow-up the QoL of patients after CD treatment in childhood is not significantly different wit QoL of healthy controls. Further studies are needed to expand the knowledge of factors that may contribute to the QoL in CD patients who were treated in childhood.PMID:34514766 | DOI:10.5114/pedm.2021.107163 (Source: Pediatric Endocrinology, Diabetes, and Metabolism)
Source: Pediatric Endocrinology, Diabetes, and Metabolism - September 13, 2021 Category: Endocrinology Authors: Katarzyna Pasternak-Pietrzak El żbieta Moszczyńska Mieczys ław Szalecki Source Type: research

Level of type 1 diabetes education of physiotherapists based on selected factors
CONCLUSIONS: The majority of the respondents had a moderate level of diabetes education. The level of the T1D knowledge of physiotherapists was primarily determined by their number of years on the job. Age and sex of the respondents had no impact on the level of their knowledge of diabetes (T1D).PMID:34514767 | DOI:10.5114/pedm.2021.107164 (Source: Pediatric Endocrinology, Diabetes, and Metabolism)
Source: Pediatric Endocrinology, Diabetes, and Metabolism - September 13, 2021 Category: Endocrinology Authors: Kamil Zaworski Zofia Kubi ńska Source Type: research

C-peptide and residual β-cell function in pediatric diabetes - state of the art
Pediatr Endocrinol Diabetes Metab. 2021;27(2):123-133. doi: 10.5114/pedm.2021.107165.ABSTRACTC-peptide, the molecule produced in an equimolar concentration to insulin, has become an established insulin secretion biomarker in diabetic patients. Measurement of C-peptide level can be helpful in clinical practice for assessing insulin-producing b-cells residual function, especially in the patients who have already started exogenous insulin therapy. Advances in assays have made measurement of C-peptide more reliable and inexpensive. Traditionally, C-peptide is widely used to differentiate between type 1, type 2 and monogenic ty...
Source: Pediatric Endocrinology, Diabetes, and Metabolism - September 13, 2021 Category: Endocrinology Authors: Milena Jamio łkowska-Sztabkowska Barbara G łowińska-Olszewska Artur Bossowski Source Type: research

Metformin - a new approach
Pediatr Endocrinol Diabetes Metab. 2021;27(2):134-140. doi: 10.5114/pedm.2021.107166.ABSTRACTMetformin is a widely used biguanide drug recommended as a first-line antidiabetic for type 2 diabetes. Currently, metformin is used not only in the treatment of diabetes but also in other diseases. Some studies have shown that metformin causes weight loss in insulin-sensitive and insulin-resistant overweight and obese patients. Metformin is an effective and safe option for women with gestational diabetes and type 2 diabetes in pregnancy, and it may also increase the ovulation rate in patients with polycystic ovary syndrome (PCOS)....
Source: Pediatric Endocrinology, Diabetes, and Metabolism - September 13, 2021 Category: Endocrinology Authors: Łucja Cwynar-Zając Source Type: research

In memoriam of Professor Leszek Szewczyk
Pediatr Endocrinol Diabetes Metab. 2021;27(2):69. doi: 10.5114/pedm.2021.107161.NO ABSTRACTPMID:34514763 | DOI:10.5114/pedm.2021.107161 (Source: Pediatric Endocrinology, Diabetes, and Metabolism)
Source: Pediatric Endocrinology, Diabetes, and Metabolism - September 13, 2021 Category: Endocrinology Authors: Iwona Be ń-Skowronek Source Type: research