Diagnosis and Treatment of Brown Tumor in the Femur Induced by Parathyroid Carcinoma: A Case Report
We report a case of a 61-year-old woman with brown tumors in both femurs due to parathyroid carcinoma. The patient presented with multiple osteolytic lesions that caused pain in the right thigh. Whole-body computed tomography (CT), including the neck, suspected a parathyroid tumor, and a biopsy of the bone lesion revealed no malignancy. Following parathyroidectomy, she was diagnosed with a brown tumor with hyperparathyroidism due to a very rare parathyroid carcinoma. Although the right femoral lesion was indicated as an impending fracture, conservative treatment was performed because of the instability of her general condi...
Source: Case Reports in Oncology - November 28, 2022 Category: Cancer & Oncology Source Type: research
Cancers, Vol. 14, Pages 5852: Mediastinal Parathyroid Cancer
This study characterizes features of mediastinal parathyroid cancer (MPC) and explores criteria aiding in the pre-operative recognition of malignancy. We assembled data from 502 patients with mediastinal parathyroid neoplasms (MPNs) from a systematic review of the literature 1968–2020 (n = 467) and our own patient cohort (n = 35). Thirty-two of the 502 MPNs (6.4%) exhibited malignancy. Only 23% of MPC patients underwent oncological surgery. Local persistence and early recurrence at a median delay of 24 months were frequent (45.8%), and associated with a 21.7-fold (95%CI 1.3–351.4; p = 0.03) high...
Source: Cancers - November 28, 2022 Category: Cancer & Oncology Authors: Klaus-Martin Schulte Gabriele Galat á Nadia Talat Tags: Article Source Type: research
Shear wave elastography for differentiating parathyroid neoplasms with malignant diagnosis or uncertain malignant potential from parathyroid adenomas: initial experience
This study aims to explore the value of 2D-shear wave elastogr... (Source: Cancer Imaging)
Source: Cancer Imaging - November 22, 2022 Category: Radiology Authors: Ruifeng Liu, Luying Gao, Xinlong Shi, Liyuan Ma, Ou Wang, Weibo Xia, Ya Hu, Yu Xia and Yuxin Jiang Tags: Research article Source Type: research
Advances in Endocrine Surgery
Recent changes in the landscape of endocrine surgery include a shift from total thyroidectomy for almost all patients with papillary thyroid cancer to the incorporation of thyroid lobectomy for well-selected patients with low-risk disease; minimally invasive parathyroidectomy with, and potentially without, intraoperative parathyroid hormone monitoring for patients with well-localized primary hyperparathyroidism; improvement in the management of parathyroid cancer with the incorporation of immune checkpoint blockade and/or targeted therapies; and the incorporation of minimally invasive techniques in the management of patien...
Source: Surgical Oncology Clinics of North America - November 3, 2022 Category: Surgery Authors: Michael S. Lui, Aditya S. Shirali, Bernice L. Huang, Sarah B. Fisher, Nancy D. Perrier Source Type: research
Late Recurrence of Hyperparathyroidism: Parathyromatosis or Recurrent Parathyroid Carcinoma?
A middle-aged woman presented with elevated calcium (10.7 mg/dL [0.28 mmol/L]) and parathyroid hormone (131 pg/mL [4,663.6 pmol/L]) levels. A sestamibi scan exhibited a right upper parathyroid lesion. Parathyroidectomy revealed a 3152 mg right upper parathyroid gland and the intraoperative parathyroid hormone level decreased by 90% (from 27.1 to 2.6 pmol/L; reference range, 1.3-6.8 pmol/L). The lesion was removed intact without any “spillage.” Histology revealed hypercellular parathyroid with intravascular tumor clusters at the periphery of the main lesion. (Source: Mayo Clinic Proceedings)
Source: Mayo Clinic Proceedings - November 1, 2022 Category: Internal Medicine Authors: Maria Gubbiotti, Virginia A. Livolsi Tags: Medical image Source Type: research
Predictive a nomogram for overall survival in patients with parathyroid cancer: A novel web-based calculator
CONCLUSION: The developed nomogram can be applied in clinical practice to help clinicians to assess patient prognosis.PMID:36307262 | DOI:10.1016/j.asjsur.2022.10.012 (Source: Asian Journal of Surgery)
Source: Asian Journal of Surgery - October 28, 2022 Category: Surgery Authors: Fangxu Yin Chong Hou Song Wang Xiaohong Wang Zhenlin Yang Source Type: research
Predictive a nomogram for overall survival in patients with parathyroid cancer: A novel web-based calculator
CONCLUSION: The developed nomogram can be applied in clinical practice to help clinicians to assess patient prognosis.PMID:36307262 | DOI:10.1016/j.asjsur.2022.10.012 (Source: Asian Journal of Surgery)
Source: Asian Journal of Surgery - October 28, 2022 Category: Surgery Authors: Fangxu Yin Chong Hou Song Wang Xiaohong Wang Zhenlin Yang Source Type: research
Parathyroid carcinoma during pregnancy: a novel pathogenic CDC73 mutation – a case report
Parathyroid carcinoma is an uncommon cause of PTH-dependent hypercalcemia. Only a handful of cases have been reported of parathyroid carcinoma during pregnancy. (Source: BMC Endocrine Disorders)
Source: BMC Endocrine Disorders - October 25, 2022 Category: Endocrinology Authors: Chinthana Dematapitiya, Chiara Perera, Sivatharshiya Pathmanathan, Vindya Subasinghe, Gayani Anandagoda, Vajira Dissanayaka, Umesha Wijenayake, Preethi Dissanayake, Kavinga Gamage, Piyumi Wijewickrama and Manilka Sumanatilleke Tags: Case report Source Type: research
Usefulness of ultrasonographic detective flow imaging to diagnose parathyroid tumors: two case reports
J Nippon Med Sch. 2022 Oct 21. doi: 10.1272/jnms.JNMS.2023_90-604. Online ahead of print.ABSTRACTParathyroid tumors (PTs) are sometimes difficult to diagnose because they are small and have a low-velocity blood flow, which can be missed by current imaging modalities. PTs consist of parathyroid adenoma (PA), parathyroid cyst, and parathyroid carcinoma (PC). Detective flow imaging (DFI) is a new imaging technology that displays a low-velocity blood flow. Herein, we report two cases in which DFI was useful for the diagnosis of PTs. One case consisted of a PA and a parathyroid cyst in close proximity, and the other was a PC. T...
Source: Journal of Nippon Medical School - October 23, 2022 Category: Universities & Medical Training Authors: Mami Matsui Tomoo Jikuzono Shoko Kure Osamu Ishibashi Haruki Akasu Iwao Sugitani Source Type: research
Usefulness of ultrasonographic detective flow imaging to diagnose parathyroid tumors: two case reports
J Nippon Med Sch. 2022 Oct 21. doi: 10.1272/jnms.JNMS.2023_90-604. Online ahead of print.ABSTRACTParathyroid tumors (PTs) are sometimes difficult to diagnose because they are small and have a low-velocity blood flow, which can be missed by current imaging modalities. PTs consist of parathyroid adenoma (PA), parathyroid cyst, and parathyroid carcinoma (PC). Detective flow imaging (DFI) is a new imaging technology that displays a low-velocity blood flow. Herein, we report two cases in which DFI was useful for the diagnosis of PTs. One case consisted of a PA and a parathyroid cyst in close proximity, and the other was a PC. T...
Source: Journal of Nippon Medical School - October 23, 2022 Category: Universities & Medical Training Authors: Mami Matsui Tomoo Jikuzono Shoko Kure Osamu Ishibashi Haruki Akasu Iwao Sugitani Source Type: research
Usefulness of ultrasonographic detective flow imaging to diagnose parathyroid tumors: two case reports
J Nippon Med Sch. 2022 Oct 21. doi: 10.1272/jnms.JNMS.2023_90-604. Online ahead of print.ABSTRACTParathyroid tumors (PTs) are sometimes difficult to diagnose because they are small and have a low-velocity blood flow, which can be missed by current imaging modalities. PTs consist of parathyroid adenoma (PA), parathyroid cyst, and parathyroid carcinoma (PC). Detective flow imaging (DFI) is a new imaging technology that displays a low-velocity blood flow. Herein, we report two cases in which DFI was useful for the diagnosis of PTs. One case consisted of a PA and a parathyroid cyst in close proximity, and the other was a PC. T...
Source: Journal of Nippon Medical School - October 23, 2022 Category: Universities & Medical Training Authors: Mami Matsui Tomoo Jikuzono Shoko Kure Osamu Ishibashi Haruki Akasu Iwao Sugitani Source Type: research
Usefulness of ultrasonographic detective flow imaging to diagnose parathyroid tumors: two case reports
J Nippon Med Sch. 2022 Oct 21. doi: 10.1272/jnms.JNMS.2023_90-604. Online ahead of print.ABSTRACTParathyroid tumors (PTs) are sometimes difficult to diagnose because they are small and have a low-velocity blood flow, which can be missed by current imaging modalities. PTs consist of parathyroid adenoma (PA), parathyroid cyst, and parathyroid carcinoma (PC). Detective flow imaging (DFI) is a new imaging technology that displays a low-velocity blood flow. Herein, we report two cases in which DFI was useful for the diagnosis of PTs. One case consisted of a PA and a parathyroid cyst in close proximity, and the other was a PC. T...
Source: Journal of Nippon Medical School - October 23, 2022 Category: Universities & Medical Training Authors: Mami Matsui Tomoo Jikuzono Shoko Kure Osamu Ishibashi Haruki Akasu Iwao Sugitani Source Type: research
Usefulness of ultrasonographic detective flow imaging to diagnose parathyroid tumors: two case reports
J Nippon Med Sch. 2022 Oct 21. doi: 10.1272/jnms.JNMS.2023_90-604. Online ahead of print.ABSTRACTParathyroid tumors (PTs) are sometimes difficult to diagnose because they are small and have a low-velocity blood flow, which can be missed by current imaging modalities. PTs consist of parathyroid adenoma (PA), parathyroid cyst, and parathyroid carcinoma (PC). Detective flow imaging (DFI) is a new imaging technology that displays a low-velocity blood flow. Herein, we report two cases in which DFI was useful for the diagnosis of PTs. One case consisted of a PA and a parathyroid cyst in close proximity, and the other was a PC. T...
Source: Journal of Nippon Medical School - October 23, 2022 Category: Universities & Medical Training Authors: Mami Matsui Tomoo Jikuzono Shoko Kure Osamu Ishibashi Haruki Akasu Iwao Sugitani Source Type: research
Usefulness of ultrasonographic detective flow imaging to diagnose parathyroid tumors: two case reports
J Nippon Med Sch. 2022 Oct 21. doi: 10.1272/jnms.JNMS.2023_90-604. Online ahead of print.ABSTRACTParathyroid tumors (PTs) are sometimes difficult to diagnose because they are small and have a low-velocity blood flow, which can be missed by current imaging modalities. PTs consist of parathyroid adenoma (PA), parathyroid cyst, and parathyroid carcinoma (PC). Detective flow imaging (DFI) is a new imaging technology that displays a low-velocity blood flow. Herein, we report two cases in which DFI was useful for the diagnosis of PTs. One case consisted of a PA and a parathyroid cyst in close proximity, and the other was a PC. T...
Source: Journal of Nippon Medical School - October 23, 2022 Category: Universities & Medical Training Authors: Mami Matsui Tomoo Jikuzono Shoko Kure Osamu Ishibashi Haruki Akasu Iwao Sugitani Source Type: research
