Methionine Restriction Extends Life in Flies
A sizable fraction of the benefits to health and life span resulting from the practice of calorie restriction derive from regulatory systems that are triggered by nutrient sensing mechanisms focused on specific amino acids, primarily methionine. Thus a lowered dietary methionine intake produces health benefits even when overall calorie intake remains the same. This is well demonstrated in animal models, but not well tested in humans, despite the existence of low methionine medical diets. This may be because the medical diet are expensive, and it is neither straightforward nor easy to plan and eat a low methionine diet. Gui...
Source: Fight Aging! - January 5, 2024 Category: Research Authors: Reason Tags: Daily News Source Type: blogs
Telehealth and VR – 2024 Health IT Predictions
As we kick off 2024, we wanted to start the new year with a series of 2024 Health IT predictions. We asked the Healthcare IT Today community to submit their predictions and we received a wide ranging set of responses that we grouped into a number of themes. In fact, we got so many that we had to narrow them down to just the best and most interesting. Check out our community’s predictions below and be sure to add your own thoughts and/or places you disagree with these predictions in the comments and on social media.
All of this year’s 2024 health IT predictions (updated as they’re shared):
John and ...
Source: EMR and HIPAA - January 4, 2024 Category: Information Technology Authors: John Lynn Tags: Ambulatory C-Suite Leadership Clinical Health IT Company Healthcare IT Hospital - Health System LTPAC Telemedicine and Remote Monitoring 2024 Health IT Predictions 98point6 Technologies Agora Andrew Norden Anish Sebastian Artisig Source Type: blogs
Deconstructing diabetes stigma: A panel discussion
In conclusion, the discussion was an enriching and eye-opening event, bringing together passionate individuals dedicated to challenging the stigma around diabetes. By amplifying our voices and working together, we can make a lasting impact on the lives of those touched by diabetes.Visit enddiabetesstigma.org and become a part of the movement for change. If you’d like to get involved in spreading more awareness about this, reach out to Dennis and/or leave a comment here.
Full transcript and show notes
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Source: Scott's Diabetes Blog - January 4, 2024 Category: Endocrinology Authors: Scott K. Johnson Tags: Blog Posts Source Type: blogs
Twin Health Secures $50M to Expand its Groundbreaking Whole Body Digital Twin Technology and Service to Reverse Chronic Metabolic Disease
Investment Fuels Twin Health’s Mission to Revolutionize Chronic Metabolic Disease Prevention and Reversal with Cutting-Edge Science, Precision Guidance, and Licensed Clinical Care Team
Twin Health, creators of the Whole Body Digital Twin service for reversing, improving, and preventing chronic metabolic diseases, announced securing $50 million in funding to continue expanding its groundbreaking technology and clinical service solutions for more members across the United States.
Twin Health introduced the Whole Body Digital Twin, a dynamic model of each individual’s unique metabolism, powered by artificial int...
Source: EMR and HIPAA - January 4, 2024 Category: Information Technology Authors: Healthcare IT News Tags: Health IT Company Healthcare IT Health IT Funding Health IT Fundings Health IT Investment Helena ICONIQ Growth Jahangir Mohammed Kevin Johnson Peak XV Sofina Temasek Twin Health Source Type: blogs
Health Equity – 2024 Health IT Predictions
As we kick off 2024, we wanted to start the new year with a series of 2024 Health IT predictions. We asked the Healthcare IT Today community to submit their predictions and we received a wide ranging set of responses that we grouped into a number of themes. In fact, we got so many that we had to narrow them down to just the best and most interesting. Check out our community’s predictions below and be sure to add your own thoughts and/or places you disagree with these predictions in the comments and on social media.
All of this year’s 2024 health IT predictions (updated as they’re shared):
John and ...
Source: EMR and HIPAA - January 2, 2024 Category: Information Technology Authors: John Lynn Tags: C-Suite Leadership Health IT Company Healthcare IT Hospital - Health System Regulations 2024 Health IT Predictions 86Borders Ali Modaressi Alice Wei Barnes & Thornburg Blue Shield of California BluePath Health Chris Bove CleanSla Source Type: blogs
A Vitamin-Like Nutrient Linked To 28% Lower Dementia Risk
People with the highest intakes had a 28 percent lower risk of dementia, the study found. (Source: PsyBlog | Psychology Blog)
Source: PsyBlog | Psychology Blog - January 2, 2024 Category: Psychiatry & Psychology Authors: Jeremy Dean Tags: Dementia Source Type: blogs
Aptamers to Reduce Inflammatory AGE-RAGE Interaction
Researchers here discuss the use of aptamers that can bind to advanced glycation endproducts (AGEs). This prevents the AGEs from themselves binding to the receptor for AGEs (RAGE), an interaction that provokes inflammation. A sizable presence of circulating, short-lived AGEs is characteristic of the abnormal metabolism of obesity and obesity-related conditions such as type 2 diabetes. It is an open question as to how much of a contribution to the chronic inflammation of aging is provided by AGEs in people of a normal weight, eating a basically sensible diet, however. The only way to find out is to test a therapy of this na...
Source: Fight Aging! - January 2, 2024 Category: Research Authors: Reason Tags: Daily News Source Type: blogs
Should We Think of Rheumatoid Arthritis as an Age-Related Condition?
There are medical conditions that occur only in old age, and there are medical conditions, such as cancer, that can occur at any point in life, but more so in the old. Then there are grey area conditions that may occur to some greater degree in later life, or be worse in later life, but this is by no means widely appreciated. Where does the autoimmune condition of rheumatoid arthritis sit in this spectrum? Unlike cancer, it is not commonly thought of as an age-related disease, even though it is certainly affected and made worse by the processes of aging. This point is discussed in today's open access commentary and the pap...
Source: Fight Aging! - January 1, 2024 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs
It is Never Too Late to Improve Health by Reducing Calorie Intake
In this study, researchers looked specifically at male flies. Young flies switched from a high calorie to a low-calorie diet at 20 days old lived very long lives, similar to the flies fed a low-calorie diet from day one. What surprised the researchers was that switching the flies' diet to a low calorie one remained a reliable way to extend lifespan even for old flies in ill health. The older insects raised on the high calorie diet had more lipids in their bodies, and they expended more energy defending their bodies from reactive oxygen species. They also had a higher death rate than flies raised on the low-calorie diet. Bu...
Source: Fight Aging! - January 1, 2024 Category: Research Authors: Reason Tags: Daily News Source Type: blogs
Fight Aging! Newsletter, January 1st 2024
Discussion of What is Need to Speed the Pace at which Drugs to Treat Aging Arrive in the Clinic
Cellular Senescence in the Aging Brain, a Contributing Cause of Cognitive Decline
Reviewing What is Known of the Mechanisms of Taurine Supplementation Relevant to Aging and Metabolism
Blunt Thoughts on Calculating the Revealed Value of Human Life
A Look Back at 2023: Progress Towards the Treatment of Aging as a Medical Condition
Towards Adjustment of the Gut Microbiome to Slow Aging
Gene Therapy Enhances Object Recognition Memory in Young and Old Mice
Benefits of Sem...
Source: Fight Aging! - December 31, 2023 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
An Obvious Sign of Vitamin D Deficiency
Levels are typically lower in the body through the winter months in northern latitudes. (Source: PsyBlog | Psychology Blog)
Source: PsyBlog | Psychology Blog - December 30, 2023 Category: Psychiatry & Psychology Authors: Jeremy Dean Tags: Nutrition Source Type: blogs
A Look Back at 2023: Progress Towards the Treatment of Aging as a Medical Condition
The market has been in the doldrums and it has been a tough year for fundraising, both for non-profits and biotech startups. The conferences have exhibited more of an academic focus as companies tightened belts and postponed investment rounds, while investors stayed home. Not that this halts the flow of hype for some projects, and nor has it slowed media commentary on the longevity industry as it presently stands. A few of the articles in that commmentary are even interesting to read! The field has grown and is more mature now than has ever been the case. Biotech of all forms is a challenging field with a high failure rate...
Source: Fight Aging! - December 29, 2023 Category: Research Authors: Reason Tags: Of Interest Source Type: blogs
Reviewing What is Known of the Mechanisms of Taurine Supplementation Relevant to Aging and Metabolism
Taurine is a semi-essential amino acid. Dietary taurine supplementation has been shown to modestly slow aging in mice, though as for all such interventions there is always the question of whether it will prove to be less useful in humans, and also whether these results in mice will be disproved by the much more rigorous Interventions Testing Program (ITP), once that group gets around to assessing taurine supplementation. Few of the numerous interventions thought to modestly slow aging in mice on the basis of earlier research actually held up once subjected to the ITP degree of experimental rigor.
Speculatively, taur...
Source: Fight Aging! - December 27, 2023 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs
Ring In the New Year With Basic Research
Empowering basic biomedical research, which focuses on understanding how living systems work, is one of NIGMS’ main goals. This type of research not only helps us learn how our bodies and those of other organisms function but also lays the foundation for advances in disease diagnosis, treatment, and prevention.
We’re excited to see what the upcoming year has in store for the field! In preparation, we’re highlighting what NIGMS-supported scientists had to say in 2023 about the many merits of basic research. Also check out the links to the Biomedical Beat posts that feature them if you haven’t already.
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Source: Biomedical Beat Blog - National Institute of General Medical Sciences - December 27, 2023 Category: Research Authors: Chrissa Chverchko Tags: Being a Scientist Scientific Process Source Type: blogs
Cellular Senescence in the Aging Brain, a Contributing Cause of Cognitive Decline
Senescent cells are created throughout the body at all stages of life, largely when somatic cells reach the Hayflick limit on replication. Senescent cells cease replication and begin to energetically produce pro-growth, pro-inflammatory factors, attracting the attention of the immune system and otherwise changing the behavior of surrounding cells. Cell stress and mutational damage can induce senescence, and in this case senescence is a mechanism that acts to limit the risk of cancer. Tissue injury also produces senescent cells, and here they help to coordinate the activities of the many different cell types that become inv...
Source: Fight Aging! - December 26, 2023 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs
