Assessing Pentadecanoic Acid In Vitro
The work on pentadecanoic acid noted here is interesting, but should be taken with a grain of salt given that it is performed in vitro. In general, one should expect any given set of mechanisms in the cell to be associated with many different means of manipulation. It is interesting to see a fatty acid capable of touching on the same mechanisms as rapamycin, but remember that the ability to influence the same mechanistic targets does not necessarily translate to the same ability to produce a modest slowing of aging in animal studies. So the usual advice stands here, to wait for the animal studies before getting too excited...
Source: Fight Aging! - November 22, 2023 Category: Research Authors: Reason Tags: Daily News Source Type: blogs
This Diet Lowers Cognitive Decline Risk By 17%
Adhering to this diet could not only lower the risk of heart disease but also boost cognitive function. (Source: PsyBlog | Psychology Blog)
Source: PsyBlog | Psychology Blog - November 21, 2023 Category: Psychiatry & Psychology Authors: Mina Dean Tags: Dementia Source Type: blogs
The Vitamin Deficiency Linked To Brain Damage
Brain shrinkage was six times more likely in those with low levels of this vitamin. (Source: PsyBlog | Psychology Blog)
Source: PsyBlog | Psychology Blog - November 21, 2023 Category: Psychiatry & Psychology Authors: Jeremy Dean Tags: Nutrition Source Type: blogs
A Therapy to Reduce Lipoprotein(a) Levels
The research and development community is ever in search of the next statin drug, and a way to reduce lipoprotein(a) levels looks very much like an alternative statin. Statins reduce the amount of cholesterol carried by LDL particles in the bloodstream. Lipoprotein(a) is a carrier of cholesterol, like LDL, and research has shown that high levels correlate with the development of atherosclerotic lesions, as is the case for LDL-cholesterol. That being so, one can't be all that optimistic that a treatment to reduce lipoprotein(a) will actually do much for disease risk. Statins reduce risk of stroke and heart attack resulting ...
Source: Fight Aging! - November 21, 2023 Category: Research Authors: Reason Tags: Daily News Source Type: blogs
The Common Signs Of Vitamin D Deficiency
Vitamin D supplementation could lower the risk of dying from cancer-related diseases and increase life expectancy by years. (Source: PsyBlog | Psychology Blog)
Source: PsyBlog | Psychology Blog - November 20, 2023 Category: Psychiatry & Psychology Authors: Mina Dean Tags: Nutrition Source Type: blogs
Restoring Lost Vascularization Capability via FDPS Inhibition
The ability of the body to build new blood vessels declines with age. One of the consequences is a loss of capillary density in tissues throughout the body, reducing the supply of nutrients and contributing to harmful changes in the fluid dynamics of the vasculature. Researchers have shown that increasing the ability to build and maintain capillaries via upregulation of VEGF can extend life in mice. Here, researchers report on another approach to increasing the capacity for vascularization in mice. The goal of increasing capillary density is an important one, but few research groups or companies are focused on this in any ...
Source: Fight Aging! - November 20, 2023 Category: Research Authors: Reason Tags: Daily News Source Type: blogs
Fight Aging! Newsletter, November 20th 2023
In this study, we attempted to further explain the role, exact mechanism and target of ICA in treating AD from the ferroptosis perspective. We found that ICA could improve the neurobehavioral, memory, and motor abilities of AD mice. It could lower the ferroptosis level and enhance the resistance to oxidative stress. After inhibition of MDM2, ICA could no longer improve the cognitive ability of AD mice, nor could it further inhibit ferroptosis. Network pharmacological analysis revealed that MDM2 might be the target of ICA action.
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Particulate Air Pollution and Its Effects on the Mechan...
Source: Fight Aging! - November 19, 2023 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
The Vitamin Deficiency That May Double Cognitive Decline Risk
Those in the study with lower vitamin levels at the start were at double the risk of significant cognitive decline. (Source: PsyBlog | Psychology Blog)
Source: PsyBlog | Psychology Blog - November 17, 2023 Category: Psychiatry & Psychology Authors: Jeremy Dean Tags: Dementia Nutrition Source Type: blogs
Zealous for Wellness: The Ongoing Quest for Standard Measures
The previous articles in this series showed how payers, providers, and digital health companies try to prove that they’re helping to create healthier patients. Sara Shanti, a partner specializing in health care at law firm Sheppard Mullin, says that organizations in the wellness space are searching for strong algorithms. But they also want to ensure that technology leads to, and clearly reflects, improved and worthwhile outcomes. This is not likely to emerge for some time. But this final article looks at how some organizations are filling the gap.
Rigor at a Weight Loss Clinic
Dr. Brett Osborn, author of the book G...
Source: EMR and HIPAA - November 16, 2023 Category: Information Technology Authors: Andy Oram Tags: AI/Machine Learning Ambulatory Analytics/Big Data Clinical Communication and Patient Experience Health IT Company Healthcare IT Hospital - Health System LTPAC Arcadia Behavior Change behavioral health BPCI Brett Osborn Clinical Source Type: blogs
Pin Me, Please
By KIM BELLARD
You had to know I’d write about the new Humane AI Pin, right?
After all, I’d been pleading for the next big thing to take the place of the smartphone, as recently as last month and as long ago as six years, so when a start-up like Humane suggests it is going to do just that, it has my attention. Even more intriguing, it is billed as an AI device, redefining “how we interact with AI.” It’s like catnip for me.
For anyone who has missed the hype – and there has been a lot of hype, for several months now – Humane is a Silicon Valley start-up founded by two former Apple employee...
Source: The Health Care Blog - November 15, 2023 Category: Consumer Health News Authors: matthew holt Tags: Health Tech AI Kim Bellard Source Type: blogs
What Are Some of the Uses of AI You ’ ve Already Seen Implemented in Healthcare?
AI is a big field in the world of healthcare. It feels as though there is a new theory on the mass potential of AI in (insert field of choice here) every. single. day. But what is actively being done right now? What organizations and fields are using AI? What sort of tasks is it being asked to do and is it doing it well? In the search for answers, we pulled aside some of our most knowledgeable members of the Healthcare IT Today Community at the recent HLTH Conference to get their experiences with AI in healthcare. We have compiled their answers in the video down below!
Dave Ross, Chief Technology Officer at Health Catalys...
Source: EMR and HIPAA - November 15, 2023 Category: Information Technology Authors: Grayson Miller Tags: AI/Machine Learning Ambulatory C-Suite Leadership Health IT Company Healthcare IT Hospital - Health System LTPAC ChatGPT Dave Ross FINN Partners Health Catalyst Healthcare AI HLTH 2023 HLTH Conference Isabel Hines Nurse Reimb Source Type: blogs
Cardiovascular Aging Correlates with Brain Aging
Many large epidemiological studies demonstrate a correlation between cardiovascular aging and the risk of suffering cognitive decline and dementia. The population size of such studies has increased in recent years with the advent of sizable national databases, such as the UK Biobank. Today's open access paper focuses on one specific aspect of cardiovascular aging, the onset of atrial fibrillation, irregular heartbeats that can be accompanied by palpitations and other worrying sensations. Atrial fibrillation can arise in combination with many of the features of cardiovascular aging, and one might argue that data on time of ...
Source: Fight Aging! - November 15, 2023 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs
Assessing Phenotypic Age Acceleration Differences by Lifestyle Choice
Phenotypic age is one of the less complicated biological age measures developed in recent years. As for all of the others, it was developed by using machine learning on a large set of human data, in this case commonly assessed blood biomarkers and their values at different ages. Thus while we know exactly what is being measured, it is an open question as to how those measurements relate to the underlying processes of aging, or indeed whether they accurately reflect all of those processes. Once one starts down the path of using lifestyle interventions to slow aging or novel therapies to repair the cell and tissue damage tha...
Source: Fight Aging! - November 15, 2023 Category: Research Authors: Reason Tags: Daily News Source Type: blogs
Zealous for Wellness: How to Replace Hype with Data
This article begins a series that looks at useful measures of health and how the companies that promote wellness programs demonstrate their success. We’ll see measurements of objective outcomes, patient-reported outcomes, and what payers look for when they can’t get direct evidence of improvements in wellness.
You’ll note, as we survey the wellness solutions and measurements used, that the leading organizations in this space are payers, not clinicians. I’m sure that doctors and nurse practitioners truly care for the overall happiness and wellbeing of their patients. But the institutions aren’t...
Source: EMR and HIPAA - November 14, 2023 Category: Information Technology Authors: Andy Oram Tags: AI/Machine Learning Ambulatory Analytics/Big Data Clinical Communication and Patient Experience Health IT Company Healthcare IT Hospital - Health System LTPAC Telemedicine and Remote Monitoring ACOs Avanade Christiana Voelker Cli Source Type: blogs
SCAN Group Makes Strategic Investment in Dina
SCAN Group, a mission-driven organization whose holdings include SCAN Health Plan, one of the nation’s largest not-for-profit Medicare Advantage plans, has made its latest strategic investment in Dina. Dina provides digital care-at-home network management and coordination solutions to help health plans and providers improve access to a variety of in-home care services.
“We are excited to support Dina and the work they are doing to innovate and deliver rapid, efficient solutions that provide access to home and community-based services,” said Deepa Sheth, Chief Corporate Development Officer at SCAN Group. “It is pa...
Source: EMR and HIPAA - November 14, 2023 Category: Information Technology Authors: Healthcare IT News Tags: Health IT Company Healthcare IT Arine Ashish V. Shah Deepa Sheth dina Guaranteed Health IT Funding Health IT Fundings Health IT Investment MedArrive Monogram Health SafelyYou SafeRide Health SCAN Group SCAN Health Plan Source Type: blogs
