New 1H-1,2,4-triazolyl derivatives as antimicrobial agents. Synthesis, biological evaluation and molecular docking
Chem Biodivers. 2024 Feb 29:e202400316. doi: 10.1002/cbdv.202400316. Online ahead of print.ABSTRACTThirteen new 1H-1,2,4-triazolyl derivatives were synthesized, and six of them were selected based on docking prediction for the investigation of their antimicrobial activity against five bacterial and eight fungal strains. All compounds demonstrated antibacterial activity with MIC lower than that of the ampicillin and chloramphenicol. In general, the most sensitive bacteria appeared to be P.fluorescens, while the plant pathogen X.campestris was the most resistant. The antifungal activity of the compounds was much better than ...
Source: Chemistry and Biodiversity - February 29, 2024 Category: Biochemistry Authors: Athina Athanasios Geronikaki Natalia Sucman Eugenia Stingaci Lucian Lupascu Anastasia Smetanscaia Vladimir Valica Livia Uncu Sergiu Shova Anthi Petrou Jasmina Glamo člija Marina Sockovic Fliur Macaev Source Type: research
Chemical profile and biological potential of essential oil of Psidium bahianum Landrum & amp; Funch (Myrtaceae)
Braz J Biol. 2024 Feb 26;84:e280487. doi: 10.1590/1519-6984.28048. eCollection 2024.ABSTRACTThe genus Psidium, belonging to the family Myrtaceae, encompasses several plant species rich in essential oils. Several studies involving different research areas have shown promising results for essential oils, which has attracted interest from diverse sectors, including pharmaceutical, food, and cosmetic industries. Thus, the objective of this study was to evaluate the biological activity of the essential oil extracted from Psidium bahianum leaves (EOPb) collected in an Atlantic Forest remnant in the northern coast of the state of...
Source: Braz J Biol - February 29, 2024 Category: Biology Authors: O L J Souza R S Souza E J Marques M C Silva H V M Boness V L C Vale Source Type: research
Chemical profile and biological potential of essential oil of Psidium bahianum Landrum & amp; Funch (Myrtaceae)
Braz J Biol. 2024 Feb 26;84:e280487. doi: 10.1590/1519-6984.28048. eCollection 2024.ABSTRACTThe genus Psidium, belonging to the family Myrtaceae, encompasses several plant species rich in essential oils. Several studies involving different research areas have shown promising results for essential oils, which has attracted interest from diverse sectors, including pharmaceutical, food, and cosmetic industries. Thus, the objective of this study was to evaluate the biological activity of the essential oil extracted from Psidium bahianum leaves (EOPb) collected in an Atlantic Forest remnant in the northern coast of the state of...
Source: Braz J Biol - February 29, 2024 Category: Biology Authors: O L J Souza R S Souza E J Marques M C Silva H V M Boness V L C Vale Source Type: research
Chemical profile and biological potential of essential oil of Psidium bahianum Landrum & amp; Funch (Myrtaceae)
Braz J Biol. 2024 Feb 26;84:e280487. doi: 10.1590/1519-6984.28048. eCollection 2024.ABSTRACTThe genus Psidium, belonging to the family Myrtaceae, encompasses several plant species rich in essential oils. Several studies involving different research areas have shown promising results for essential oils, which has attracted interest from diverse sectors, including pharmaceutical, food, and cosmetic industries. Thus, the objective of this study was to evaluate the biological activity of the essential oil extracted from Psidium bahianum leaves (EOPb) collected in an Atlantic Forest remnant in the northern coast of the state of...
Source: Braz J Biol - February 29, 2024 Category: Biology Authors: O L J Souza R S Souza E J Marques M C Silva H V M Boness V L C Vale Source Type: research
Chemical profile and biological potential of essential oil of Psidium bahianum Landrum & amp; Funch (Myrtaceae)
Braz J Biol. 2024 Feb 26;84:e280487. doi: 10.1590/1519-6984.28048. eCollection 2024.ABSTRACTThe genus Psidium, belonging to the family Myrtaceae, encompasses several plant species rich in essential oils. Several studies involving different research areas have shown promising results for essential oils, which has attracted interest from diverse sectors, including pharmaceutical, food, and cosmetic industries. Thus, the objective of this study was to evaluate the biological activity of the essential oil extracted from Psidium bahianum leaves (EOPb) collected in an Atlantic Forest remnant in the northern coast of the state of...
Source: Braz J Biol - February 29, 2024 Category: Biology Authors: O L J Souza R S Souza E J Marques M C Silva H V M Boness V L C Vale Source Type: research
Chemical profile and biological potential of essential oil of Psidium bahianum Landrum & amp; Funch (Myrtaceae)
Braz J Biol. 2024 Feb 26;84:e280487. doi: 10.1590/1519-6984.28048. eCollection 2024.ABSTRACTThe genus Psidium, belonging to the family Myrtaceae, encompasses several plant species rich in essential oils. Several studies involving different research areas have shown promising results for essential oils, which has attracted interest from diverse sectors, including pharmaceutical, food, and cosmetic industries. Thus, the objective of this study was to evaluate the biological activity of the essential oil extracted from Psidium bahianum leaves (EOPb) collected in an Atlantic Forest remnant in the northern coast of the state of...
Source: Braz J Biol - February 29, 2024 Category: Biology Authors: O L J Souza R S Souza E J Marques M C Silva H V M Boness V L C Vale Source Type: research
Inhibitory Effects of Endemic Thyme's Thymol-Carvacrol Chemotype Essential Oil On Aspergillus Species with Free Radical Scavenging Properties
Chem Biodivers. 2024 Feb 28:e202302115. doi: 10.1002/cbdv.202302115. Online ahead of print.ABSTRACTThe study focused on utilizing the anti-fungal and antioxidant properties of essential oils from Thymus daenensis Celak. subsp. daenensis to combat the growth of mycotoxin-producing Aspergillus species, including A. flavus, A. parasiticus, and A. niger, all common food and agricultural contaminants. The essential oil exhibited significant antifungal activity, accompanied by notable antioxidant properties. The essential oils from T. daenensis Celak. subsp. daenensis displayed significant inhibitory effects on all three Aspergi...
Source: Chemistry and Biodiversity - February 28, 2024 Category: Biochemistry Authors: Seyed Fazel Mirahmadi Alireza Shayganfar Source Type: research
Preparation and characterization of biodegradable food packaging films using lemon peel pectin and chitosan incorporated with neem leaf extract and its application on apricot fruit
Int J Biol Macromol. 2024 Feb 25:130358. doi: 10.1016/j.ijbiomac.2024.130358. Online ahead of print.ABSTRACTThe present study aims to develop and characterize biodegradable packaging films from lemon peel-derived pectin and chitosan incorporated with a bioactive extract from neem leaves. The films (PCNE) contained varying concentrations of neem leaf extract and were comprehensively assessed for their physical, optical, mechanical, and antimicrobial attributes. The thickness, moisture content, water solubility, and water vapor permeability of the biodegradable packaging films increased with the increasing concentration of n...
Source: International Journal of Biological Macromolecules - February 27, 2024 Category: Biochemistry Authors: Sadia Firdaus Faizan Ahmad Sadaf Zaidi Source Type: research
Investigation of Physicochemical Characteristics of Aspergillus niger Biomass and Examination of Its Ability to Separate Butyl Acetate Isomers
Appl Biochem Biotechnol. 2024 Feb 27. doi: 10.1007/s12010-024-04881-y. Online ahead of print.ABSTRACTAspergillus niger is a species of fungus that is widely found in natural ecosystems and has an important role in various industrial fields and is readily available. To study the adhesion of microbial cells to solid substrates and to improve their properties, physicochemical characterization of microorganisms is extremely important. For this purpose, in this study, the surface properties of A. niger biomass were determined at low cost and with high accuracy by inverse gas chromatography (IGC), a physicochemical characterizat...
Source: Applied Biochemistry and Biotechnology - February 27, 2024 Category: Biochemistry Authors: Birol Isik Mesut Bilgi Source Type: research
Expansion of Neisseria meningitidis Serogroup C Clonal Complex 10217 during Meningitis Outbreak, Burkina Faso, 2019
Emerg Infect Dis. 2024 Mar;30(3):460-468. doi: 10.3201/eid3003.221760.ABSTRACTDuring January 28-May 5, 2019, a meningitis outbreak caused by Neisseria meningitidis serogroup C (NmC) occurred in Burkina Faso. Demographic and laboratory data for meningitis cases were collected through national case-based surveillance. Cerebrospinal fluid was collected and tested by culture and real-time PCR. Among 301 suspected cases reported in 6 districts, N. meningitidis was the primary pathogen detected; 103 cases were serogroup C and 13 were serogroup X. Whole-genome sequencing revealed that 18 cerebrospinal fluid specimens tested posit...
Source: Emerging Infectious Diseases - February 26, 2024 Category: Infectious Diseases Authors: Joann F Kekeisen-Chen Felix T Tarbangdo Shalabh Sharma Daya Marasini Henju Marjuki Janelle L Kibler Heather E Reese Seydou Ouattara Flavien H Ake Issaka Yameogo Issa Ouedraogo Emmanuel Seini Robert L Zoma Issa Tonde Mahamoudou Sanou Ryan T Novak Lucy A Mc Source Type: research
Biodegradation capabilities of filamentous fungi in high-concentration heavy crude oil environments
Arch Microbiol. 2024 Feb 26;206(3):123. doi: 10.1007/s00203-024-03835-6.ABSTRACTIn this comprehensive study, we delved into the capabilities of five fungal strains: Aspergillus flavus, Aspergillus niger, Penicillium chrysogenum, Penicillium glabrum, and Penicillium rubens (the latter isolated from heavy crude oil [HCO]) in metabolizing HCO as a carbon source. Employing a meticulously designed experimental approach, conducted at room temperature (25 °C), we systematically explored various culture media and incubation periods. The results unveiled the exceptional resilience of all these fungi to HCO, with A. flavus standing...
Source: Archives of Microbiology - February 26, 2024 Category: Microbiology Authors: Jessica Zerimar C áceres-Zambrano Leonardo Andr és Rodríguez-Córdova C ésar Antonio Sáez-Navarrete Yoandy Coca Rives Source Type: research
A Dosimetric Comparative Study of Carbon-Ion Radiotherapy Versus X-ray Volumetric Modulated Arc Therapy for Stage III Non-Small-Cell Lung Cancer
CONCLUSIONS: Compared with photon VMAT, 2D-CIRT using the passive beam scanning technique significantly reduces the radiation dose to the OARs in curative radiotherapy of stage III NSCLC, suggesting a better protection of the normal tissues.PMID:38409153 | DOI:10.4103/njcp.njcp_734_23 (Source: Clinical Lung Cancer)
Source: Clinical Lung Cancer - February 26, 2024 Category: Cancer & Oncology Authors: X-J Li C-R Li Y-C Ye Y-S Zhang X-Q Zong C L Feng Source Type: research
Atherogenic Index, Cardiovascular Risk Ratio, and Atherogenic Coefficient as Risk Factors for Cardiovascular Disease in Pre-eclampsia in Southeast Nigeria: A Cross-Sectional Study
CONCLUSION: Pre-eclampsia is associated with an increased risk of CVDs. Determining the atherogenic indices and assessing the AIP level in pre-eclamptic women may predict disease risk and help in early management and measures for its prevention.PMID:38409151 | DOI:10.4103/njcp.njcp_633_23 (Source: Atherosclerosis)
Source: Atherosclerosis - February 26, 2024 Category: Cardiology Authors: P U Agu M N Egbugara J S Ogboi L O Ajah U I Nwagha E O Ugwu E C Ezugwu Source Type: research
Expansion of Neisseria meningitidis Serogroup C Clonal Complex 10217 during Meningitis Outbreak, Burkina Faso, 2019
Emerg Infect Dis. 2024 Mar;30(3):460-468. doi: 10.3201/eid3003.221760.ABSTRACTDuring January 28-May 5, 2019, a meningitis outbreak caused by Neisseria meningitidis serogroup C (NmC) occurred in Burkina Faso. Demographic and laboratory data for meningitis cases were collected through national case-based surveillance. Cerebrospinal fluid was collected and tested by culture and real-time PCR. Among 301 suspected cases reported in 6 districts, N. meningitidis was the primary pathogen detected; 103 cases were serogroup C and 13 were serogroup X. Whole-genome sequencing revealed that 18 cerebrospinal fluid specimens tested posit...
Source: Emerging Infectious Diseases - February 26, 2024 Category: Infectious Diseases Authors: Joann F Kekeisen-Chen Felix T Tarbangdo Shalabh Sharma Daya Marasini Henju Marjuki Janelle L Kibler Heather E Reese Seydou Ouattara Flavien H Ake Issaka Yameogo Issa Ouedraogo Emmanuel Seini Robert L Zoma Issa Tonde Mahamoudou Sanou Ryan T Novak Lucy A Mc Source Type: research
Evaluating the mechanism of soybean meal protein for boosting the laccase-catalyzed of thymol onto lignosulfonate via restraining non-specific adsorption
Int J Biol Macromol. 2024 Feb 23;263(Pt 2):130367. doi: 10.1016/j.ijbiomac.2024.130367. Online ahead of print.ABSTRACTThe control of laccase-catalyzed efficiency often relies on the utilization of modifying enzyme molecules and shielding agents. However, their elevated costs or carcinogenicity led to the inability for large-scale application. To address this concern, we found that a low-cost protein from soybean meal can reduce lignin's ineffective adsorption onto enzymes for improving the efficiency of thymol grafting to lignosulfonate. The results demonstrated that by adding 0.5 mg/mL of additional soybean meal protein, ...
Source: International Journal of Biological Macromolecules - February 24, 2024 Category: Biochemistry Authors: Zhiwei Fan Weichao Xia Huili Zhang Dandan Peng Shuaibo Han Xinxing Wu Fangli Sun Source Type: research
