Design, synthesis, characterization, in vitro cytotoxic, antimicrobial, antioxidant studies, DFT, thermal and molecular docking evaluation of biocompatible Co(II) complexes of N < sub > 4 < /sub > O < sub > 4 < /sub > -macrocyclic ligands
Comput Biol Chem. 2024 Feb 22;110:108032. doi: 10.1016/j.compbiolchem.2024.108032. Online ahead of print.ABSTRACTBioactive cobalt (II) macrocyclic complexes [Co(N4O4ML1)Cl2]-[Co(N4O4ML3)Cl2] have been synthesized by using the macrocyclic ligands [N4O4ML1], [N4O4ML2], and [N4O4ML3] that have an N4O4 core. These three macrocyclic ligands were all isolated in pure form, together with their complexes. Microanalytical investigations, FT-IR NMR, Mass, magnetic moments, electronic, PXRD, TGA, and EPR spectrum studies were used to analyse their structures. For these complexes, an octahedral geometry is proposed for the metal ion. ...
Source: Computational Biology and Chemistry - March 4, 2024 Category: Bioinformatics Authors: None Subhash Manish Kumar Anita Phor Monika Gupta Ashu Chaudhary Source Type: research

Using Total Cohort Fertility in Adolescence (TCFA) to analyse adolescent fertility trends and factors in Niger: Evidence from 1992 to 2012 demographic and health surveys
Afr J Reprod Health. 2024 Feb 29;28(2):13-30. doi: 10.29063/ajrh2024/v28i2.2.ABSTRACTGirls aged 10-19 currently represent 12% of Niger's population (2020). And this number continues to grow as the fertility rate is higher while mortality is declining faster. Using Niger's demographic and health surveys carried out between 1992 and 2012, the study investigated adolescent fertility, its trends and associated factors. It mobilised descriptive methods (Total cohort fertility in adolescence (TCFA) computation, distribution of the number of adolescent births, and computation of adolescent cohort childbearing mean age) and multiv...
Source: African Journal of Reproductive Health - March 1, 2024 Category: African Health Authors: Adama Ouedraogo Source Type: research