How Outreach Training and Supportive Supervision (OTSS) Affect Health Facility Readiness and Health-Care Worker Competency to Prevent and Treat Malaria in Niger: A Secondary Analysis of OTSS Data
Am J Trop Med Hyg. 2024 Feb 6:tpmd230359. doi: 10.4269/ajtmh.23-0359. Online ahead of print.ABSTRACTThe quality of health services is key to the goal of averting morbidity and mortality from malaria. From July 2020 to August 2021, PMI Impact Malaria supported the implementation of four rounds of Outreach Training and Supportive Supervision (OTSS) in 12 health districts in the two regions of Niger: Dosso and Tahoua. Through OTSS, trained supervisors conducted onsite visits to observe an average of 174 healthcare workers (HCWs) per round in 96 public primary health facilities, managing persons with fever or conducting antena...
Source: Am J Trop Med Hyg - February 6, 2024 Category: Infectious Diseases Authors: Daniel Koko Djibrilla Arouna Yves-Marie Bernard Thierno Ba Jadmin Mostel Yahaya Abdou Eric Coulibaly Zilahatou Bahari-Tohon Lawrence M Barat Source Type: research

Outreach Training and Supportive Supervision for Quality Malaria Service Delivery: A Qualitative Evaluation in 11 Sub-Saharan African Countries
Am J Trop Med Hyg. 2024 Feb 6:tpmd230316. doi: 10.4269/ajtmh.23-0316. Online ahead of print.ABSTRACTQuality improvement of malaria services aims to ensure that more patients receive accurate diagnosis, appropriate treatment, and referral. The Outreach Training and Supportive Supervision Plus (OTSS+) approach seeks to improve health facility readiness and provider competency through onsite supportive supervision, troubleshooting, and on-the-job training. As part of a multicomponent evaluation, qualitative research was conducted to understand the value of the OTSS+ approach for malaria quality improvement. Semistructured key...
Source: Am J Trop Med Hyg - February 6, 2024 Category: Infectious Diseases Authors: Robin Altaras Matt Worges Sabrina La Torre Bala M Audu Grace Mwangi Albert Zeh-Meka Paul Yikpotey Irenee Domkam Kammogne Pascalina Chanda-Kapata Caroline Vanderick Joshua Yukich Elizabeth Streat Source Type: research

How Outreach Training and Supportive Supervision (OTSS) Affect Health Facility Readiness and Health-Care Worker Competency to Prevent and Treat Malaria in Niger: A Secondary Analysis of OTSS Data
Am J Trop Med Hyg. 2024 Feb 6:tpmd230359. doi: 10.4269/ajtmh.23-0359. Online ahead of print.ABSTRACTThe quality of health services is key to the goal of averting morbidity and mortality from malaria. From July 2020 to August 2021, PMI Impact Malaria supported the implementation of four rounds of Outreach Training and Supportive Supervision (OTSS) in 12 health districts in the two regions of Niger: Dosso and Tahoua. Through OTSS, trained supervisors conducted onsite visits to observe an average of 174 healthcare workers (HCWs) per round in 96 public primary health facilities, managing persons with fever or conducting antena...
Source: The American Journal of Tropical Medicine and Hygiene - February 6, 2024 Category: Tropical Medicine Authors: Daniel Koko Djibrilla Arouna Yves-Marie Bernard Thierno Ba Jadmin Mostel Yahaya Abdou Eric Coulibaly Zilahatou Bahari-Tohon Lawrence M Barat Source Type: research

Outreach Training and Supportive Supervision for Quality Malaria Service Delivery: A Qualitative Evaluation in 11 Sub-Saharan African Countries
Am J Trop Med Hyg. 2024 Feb 6:tpmd230316. doi: 10.4269/ajtmh.23-0316. Online ahead of print.ABSTRACTQuality improvement of malaria services aims to ensure that more patients receive accurate diagnosis, appropriate treatment, and referral. The Outreach Training and Supportive Supervision Plus (OTSS+) approach seeks to improve health facility readiness and provider competency through onsite supportive supervision, troubleshooting, and on-the-job training. As part of a multicomponent evaluation, qualitative research was conducted to understand the value of the OTSS+ approach for malaria quality improvement. Semistructured key...
Source: The American Journal of Tropical Medicine and Hygiene - February 6, 2024 Category: Tropical Medicine Authors: Robin Altaras Matt Worges Sabrina La Torre Bala M Audu Grace Mwangi Albert Zeh-Meka Paul Yikpotey Irenee Domkam Kammogne Pascalina Chanda-Kapata Caroline Vanderick Joshua Yukich Elizabeth Streat Source Type: research

Pemigatinib for patients with previously treated, locally advanced or metastatic cholangiocarcinoma harboring FGFR2 fusions or rearrangements: a joint analysis of the multicenter, observational, real-world French PEMI-BIL and Italian PEMI-REAL cohort studies
Pemigatinib is approved for patients with pretreated, locally advanced or metastatic CCA harboring FGFR2 rearrangements or fusions. We aim to assess the effectiveness and safety of pemigatinib in real-world setting. (Source: European Journal of Cancer)
Source: European Journal of Cancer - February 5, 2024 Category: Cancer & Oncology Authors: Alessandro Parisi, Blandine Delaunay, Giada Pinterpe, Antoine Hollebecque, Jean Frederic Blanc, Mohamed Bouattour, Eric Assenat, Meher Ben Abdelghani, Matthieu Sarabi, Monica Niger, Caterina Vivaldi, Mario Mandal à, Andrea Palloni, Maria Bensi, Silvio Ke Tags: Original Research Source Type: research

A Clinical Study on Microbiological Profile in Tracheostomy Wounds
This study was a retrospective analysis of microbiological profile, antibiotic sensitivity& resistance pattern in patients with a tracheostomized wound. A retrospective review of the microbiological profiles of all adult patients who underwent a tracheostomy was conducted between May 2022 and May 2023 at our hospital. Based on the tracheostomy indications, patients were allocated under obstructed and non-obstructed group. Any patient with at least one positive sample was followed up quarterly for a year. The first culture result obtained was recorded at least one month following the last antibiotic dose in each quarter...
Source: Indian Journal of Otolaryngology and Head and Neck Surgery - February 3, 2024 Category: ENT & OMF Source Type: research

Cultivation of recombinant Aspergillus niger strains on dairy whey as a carbohydrate source
J Ind Microbiol Biotechnol. 2024 Jan 9;51:kuae007. doi: 10.1093/jimb/kuae007.ABSTRACTAgricultural waste valorisation provides a sustainable solution to waste management, and combining waste utilisation with commodity production allows for responsible production processes. Recombinant Aspergillus niger D15 strains expressing fungal endoglucanases (Trichoderma reesei eg1 and eg2 and Aspergillus carneus aceg) were evaluated for their ability to utilise lactose as a carbon source to determine whether dairy waste could be used as a feedstock for enzyme production. The recombinant A. niger D15[eg1]PyrG, D15[eg2]PyrG, and D15[ace...
Source: Journal of Industrial Microbiology and Biotechnology - February 1, 2024 Category: Microbiology Authors: Teagan C Crament Kayline Arendsen Shaunita H Rose Trudy Jansen Source Type: research

Cultivation of recombinant Aspergillus niger strains on dairy whey as a carbohydrate source
J Ind Microbiol Biotechnol. 2024 Jan 9;51:kuae007. doi: 10.1093/jimb/kuae007.ABSTRACTAgricultural waste valorisation provides a sustainable solution to waste management, and combining waste utilisation with commodity production allows for responsible production processes. Recombinant Aspergillus niger D15 strains expressing fungal endoglucanases (Trichoderma reesei eg1 and eg2 and Aspergillus carneus aceg) were evaluated for their ability to utilise lactose as a carbon source to determine whether dairy waste could be used as a feedstock for enzyme production. The recombinant A. niger D15[eg1]PyrG, D15[eg2]PyrG, and D15[ace...
Source: Journal of Industrial Microbiology and Biotechnology - February 1, 2024 Category: Microbiology Authors: Teagan C Crament Kayline Arendsen Shaunita H Rose Trudy Jansen Source Type: research

Cultivation of recombinant Aspergillus niger strains on dairy whey as a carbohydrate source
J Ind Microbiol Biotechnol. 2024 Jan 9;51:kuae007. doi: 10.1093/jimb/kuae007.ABSTRACTAgricultural waste valorisation provides a sustainable solution to waste management, and combining waste utilisation with commodity production allows for responsible production processes. Recombinant Aspergillus niger D15 strains expressing fungal endoglucanases (Trichoderma reesei eg1 and eg2 and Aspergillus carneus aceg) were evaluated for their ability to utilise lactose as a carbon source to determine whether dairy waste could be used as a feedstock for enzyme production. The recombinant A. niger D15[eg1]PyrG, D15[eg2]PyrG, and D15[ace...
Source: Journal of Industrial Microbiology and Biotechnology - February 1, 2024 Category: Microbiology Authors: Teagan C Crament Kayline Arendsen Shaunita H Rose Trudy Jansen Source Type: research

Synergistically Coupling Atomic ‐Level Defect‐Manipulation and Nanoscopic‐Level Interfacial Engineering Enables Fast and Durable Sodium Storage
Carbon-packaged defective-rich SnSSe nanosheets grafted onto Aspergillus niger spores-derived hollow-carbon (ANDC@SnSSe@C) is constructed. Benefiting from the remarkable advantages of ingenious nanoarchitectures, the ANDC@SnSSe@C composites afford a remarkable long-cycle durability and admirable high-rate capability. AbstractThrough inducing interlayer anionic ligands and functionally modifying conductive carbon-skeleton on the transition metal chalcogenides (TMCs) parent to achieve atomic-level defect-manipulation and nanoscopic-level architecture design is of great significance, which can broaden interlayer distance, opt...
Source: Small - January 31, 2024 Category: Nanotechnology Authors: Wenxi Zhao, Xiaoqing Ma, Xiaodeng Wang, Hao Zhou, Xun He, Yongchao Yao, Yuchun Ren, Yongsong Luo, Dongdong Zheng, Shengjun Sun, Qian Liu, Luming Li, Wei Chu, Yan Wang, Xuping Sun Tags: Research Article Source Type: research

Manipulation of co-pelletization for Chlorela vulgaris harvest by treatment of Aspergillus niger spore
In this study,Aspergillus niger andChlorella vulgaris were used as the model species of filamentous fungi and microalgae to investigate co-pellets formation usingA. niger spores after by different pH solutions treatment, swelling, snailase treatment. The importance of spore treatments onC. vulgaris harvest in sequence was claimed based on response surface methodology analysis. The pH solutions treatment, swelling, snailase treatment ofA. niger spore contributed 21.0%, 10.5%, 40.7% of harvest ratio ofC. vulgaris respectively, which guided the application of spore treatment into co-pelletization. Treatment of spore was showe...
Source: World Journal of Microbiology and Biotechnology - January 30, 2024 Category: Microbiology Source Type: research

Pulmonary Aspergillosis in People with Cystic Fibrosis
Semin Respir Crit Care Med 2024; 45: 128-140 DOI: 10.1055/s-0043-1777267In the last decade, fungal respiratory diseases have been increasingly investigated for their impact on the clinical course of people with cystic fibrosis (CF), with a particular focus on infections caused by Aspergillus spp. The most common organisms from this genus detected from respiratory cultures are Aspergillus fumigatus and Aspergillus terreus, followed by Aspergillus flavus, Aspergillus niger, and Aspergillus nidulans. These species have been identified to be both chronic colonizers and sources of active infection and may negatively impact lung...
Source: Seminars in Respiratory and Critical Care Medicine - January 29, 2024 Category: Respiratory Medicine Authors: Schwarz, C. Eschenhagen, P.N. Mainz, J.G. Schmidergall, T. Schuette, H. Romanowska, E. Tags: Review Article Source Type: research

First identification of Microsporidia MB in Anopheles coluzzii from Zinder City, Niger
Malaria, a disease transmitted by Anopheles mosquitoes, is a major public health problem causing millions of deaths worldwide, mostly among children under the age of 5 years. Biotechnological interventions target... (Source: Parasites and Vectors)
Source: Parasites and Vectors - January 29, 2024 Category: Microbiology Authors: Lamine Mahaman Moustapha, Illiassou Mamane Sadou, Ibrahima Issa Arzika, Laminou Ibrahim Maman, Michel K. Gomgnimbou, Maurice Konkobo, Abdoulaye Diabate and Etienne Bilgo Tags: Brief Report Source Type: research

Study on the control effect and physiological mechanism of Wickerhamomyces anomalus on primary postharvest diseases of peach fruit
Int J Food Microbiol. 2024 Mar 2;413:110575. doi: 10.1016/j.ijfoodmicro.2024.110575. Epub 2024 Jan 15.ABSTRACTBrown rot, aspergillosis and soft rot are the primary diseases of postharvest peach fruit. Our study aimed to investigate the biocontrol effect of Wickerhamomyces anomalus on the primary postharvest diseases of peach fruit and to explore its underlying physiological mechanism. The findings demonstrated that W. anomalus had an obvious inhibitory effect on Monilinia fructicola, Aspergillus niger and Rhizopus stolonifer. At the same time, W. anomalus can grow stably on the wound and surface of peach fruit at 25 °C an...
Source: International Journal of Food Microbiology - January 20, 2024 Category: Food Science Authors: Yali Zhou Lina Zhao Yaqi Chen Solairaj Dhanasekaran Xifei Chen Xiaoyun Zhang Xiangzheng Yang Maoyu Wu Yuanda Song Hongyin Zhang Source Type: research

Epidemiological behaviour and interventions of malaria in Niger, 2010 –2019: a time-series analysis of national surveillance data
Malaria remains a significant public health concern in Niger, with the number of cases increasing from 592,334 in 2000 to 3,138,696 in 2010. In response, a concerted campaign against the disease has been initi... (Source: Malaria Journal)
Source: Malaria Journal - January 19, 2024 Category: Infectious Diseases Authors: Ali Issakou Malam Tchole, Run-Ze Ye, Qing Xu, Zhen-Wei Li, Jin-Yue Liu, Shan-Shan Wang, Jing Liu, Xiao-Yang Wang, Alassan Maman Bachir, Lin Zhao and Wu-Chun Cao Tags: Research Source Type: research