Risk factors associated with congenital central nervous system abnormalities in the National Hospital of Zinder, Niger
CONCLUSION: Risk factors such as family malformation history and consanguine marriage increased the risk of developing congenital malformations of the central nervous system. In contrast, folic acid supplementation in the index period and multiparity had a significant protective effect.PMID:38458060 | DOI:10.1016/j.neuchi.2024.101547 (Source: Neuro-Chirurgie)
Source: Neuro-Chirurgie - March 8, 2024 Category: Neurosurgery Authors: Rabiou Mahaman Sani Hamissou Moussa Maman Roufai George Thomas Ibrahim Hassane Ali Amadou Hounkpatin Seton Stachys Beranger Source Type: research
Risk factors associated with congenital central nervous system abnormalities in the National Hospital of Zinder, Niger
CONCLUSION: Risk factors such as family malformation history and consanguine marriage increased the risk of developing congenital malformations of the central nervous system. In contrast, folic acid supplementation in the index period and multiparity had a significant protective effect.PMID:38458060 | DOI:10.1016/j.neuchi.2024.101547 (Source: Neurochirurgie)
Source: Neurochirurgie - March 8, 2024 Category: Neurosurgery Authors: Rabiou Mahaman Sani Hamissou Moussa Maman Roufai George Thomas Ibrahim Hassane Ali Amadou Hounkpatin Seton Stachys Beranger Source Type: research
‘Failure at every level’: How science sleuths exposed massive ethics violations at a famed French institute
With six studies published in the 2010s, French microbiologist Didier Raoult added to his already vast publication record. He and his colleagues conducted a wide range of investigations into infectious diseases and their treatments. They took stool samples from patients on long-term antibiotic treatment, looking for alterations in their gut microbiome. They swabbed the throats of pilgrims leaving France for Mecca, searching for evidence of a bacterium that causes brain abscesses. And they studied samples of heart valves and blood clots from patients with heart inflammation to refine tests for the bacteria that cause the co...
Source: Science of Aging Knowledge Environment - March 7, 2024 Category: Geriatrics Source Type: research
Aspergillus niger pneumonia as superinfection in a patient with pulmonary tuberculosis
We report a patient with severe cavitary pulmonary tuberculosis and Aspergillus niger superinfection, whose only comorbidity was untreated diabetes mellitus. A. niger pneumonia was proven by PCR, sequencing and culture of pleural and respiratory secretions. The patient was successfully treated with a four-drug antituberculous regimen, liposomal amphotericin B (up to 5 mg/kg/d) and pleuro-pneumonectomy. Histology of the resected lung revealed destroyed lung tissue with inflammatory cells and fungal conidia. There were large deposits of polarising material, which was found to be calcium oxalate. There was also nodular caseat...
Source: Pneumologie - March 7, 2024 Category: Respiratory Medicine Authors: Santiago Ewig S ören Gatermann Stathis Phillipou Christian Giesa Erich Hecker Source Type: research
Characterization and decontamination of deposited dust: a management regime at a museum
AbstractDeposited dust represents a nutritional niche for microflora. Inhibiting microflora-associated deposited dust is a critical approach to manage cultural heritage buildings. Knowledge on the effectiveness of commercial disinfection on microflora in a real field environment is limited. The present study aims to: (1) characterize deposited dust composition, and (2) assess the effectiveness of several commercial biocides/and an air ionizer on microflora-associated floor surface and air before and after treatment. Deposited dust was collected using a dust collector and microbial air sampling was conducted via a volumetri...
Source: Aerobiologia - March 5, 2024 Category: Environmental Health Source Type: research
Design, synthesis, characterization, in vitro cytotoxic, antimicrobial, antioxidant studies, DFT, thermal and molecular docking evaluation of biocompatible Co(II) complexes of N < sub > 4 < /sub > O < sub > 4 < /sub > -macrocyclic ligands
Comput Biol Chem. 2024 Feb 22;110:108032. doi: 10.1016/j.compbiolchem.2024.108032. Online ahead of print.ABSTRACTBioactive cobalt (II) macrocyclic complexes [Co(N4O4ML1)Cl2]-[Co(N4O4ML3)Cl2] have been synthesized by using the macrocyclic ligands [N4O4ML1], [N4O4ML2], and [N4O4ML3] that have an N4O4 core. These three macrocyclic ligands were all isolated in pure form, together with their complexes. Microanalytical investigations, FT-IR NMR, Mass, magnetic moments, electronic, PXRD, TGA, and EPR spectrum studies were used to analyse their structures. For these complexes, an octahedral geometry is proposed for the metal ion. ...
Source: Computational Biology and Chemistry - March 4, 2024 Category: Bioinformatics Authors: None Subhash Manish Kumar Anita Phor Monika Gupta Ashu Chaudhary Source Type: research
