Two undescribed compounds from < em > Aspergillus Niger < /em > , an endophytic fungus isolated from < em > Camellia flavida < /em >
Nat Prod Res. 2024 Mar 29:1-8. doi: 10.1080/14786419.2024.2334325. Online ahead of print.ABSTRACTA new naphtho-γ-pyrone dimer, asperosperma A, and a new methyl nicotinate derivative, asperosperma B, with 12 known compounds were isolated from the endophytic fungus Aspergillus niger from the stem of Camellia flavida. Their structure was elucidated by NMR, ECD spectrum, and HR-ESI-MS data. Asperosperma A exhibited a highly cytotoxicity against H460 and 4T1 cancer cells with the IC50 values were 0.37 ± 0.06 and 2.04 ± 0.79 μM, respectively. Moreover, it showed a highly sensitive against Staphylococcus aureus, Escherichia c...
Source: Natural Product Research - March 29, 2024 Category: Biochemistry Authors: Siyuan Ma Li Ge Hongyu Lu Jianhua Yan Kedi Yang Source Type: research

Two undescribed compounds from < em > Aspergillus Niger < /em > , an endophytic fungus isolated from < em > Camellia flavida < /em >
Nat Prod Res. 2024 Mar 29:1-8. doi: 10.1080/14786419.2024.2334325. Online ahead of print.ABSTRACTA new naphtho-γ-pyrone dimer, asperosperma A, and a new methyl nicotinate derivative, asperosperma B, with 12 known compounds were isolated from the endophytic fungus Aspergillus niger from the stem of Camellia flavida. Their structure was elucidated by NMR, ECD spectrum, and HR-ESI-MS data. Asperosperma A exhibited a highly cytotoxicity against H460 and 4T1 cancer cells with the IC50 values were 0.37 ± 0.06 and 2.04 ± 0.79 μM, respectively. Moreover, it showed a highly sensitive against Staphylococcus aureus, Escherichia c...
Source: Natural Product Research - March 29, 2024 Category: Biochemistry Authors: Siyuan Ma Li Ge Hongyu Lu Jianhua Yan Kedi Yang Source Type: research

Two undescribed compounds from < em > Aspergillus Niger < /em > , an endophytic fungus isolated from < em > Camellia flavida < /em >
Nat Prod Res. 2024 Mar 29:1-8. doi: 10.1080/14786419.2024.2334325. Online ahead of print.ABSTRACTA new naphtho-γ-pyrone dimer, asperosperma A, and a new methyl nicotinate derivative, asperosperma B, with 12 known compounds were isolated from the endophytic fungus Aspergillus niger from the stem of Camellia flavida. Their structure was elucidated by NMR, ECD spectrum, and HR-ESI-MS data. Asperosperma A exhibited a highly cytotoxicity against H460 and 4T1 cancer cells with the IC50 values were 0.37 ± 0.06 and 2.04 ± 0.79 μM, respectively. Moreover, it showed a highly sensitive against Staphylococcus aureus, Escherichia c...
Source: Natural Product Research - March 29, 2024 Category: Biochemistry Authors: Siyuan Ma Li Ge Hongyu Lu Jianhua Yan Kedi Yang Source Type: research

Cost-effectiveness of severe acute malnutrition treatment delivered by community health workers in the district of Mayahi, Niger
A non-randomized controlled trial, conducted from June 2018 to March 2019 in two rural communes in the health district of Mayahi in Niger, showed that including community health workers (CHWs) in the treatment... (Source: Human Resources for Health)
Source: Human Resources for Health - March 29, 2024 Category: Health Management Authors: Elisa M. Molanes-L ópez, José M. Ferrer, Abdias Ogobara Dougnon, Abdoul Aziz Gado, Atté Sanoussi, Nassirou Ousmane, Ramatoulaye Hamidou Lazoumar and Pilar Charle-Cuéllar Tags: Research Source Type: research

Unravelling the Antimicrobial, Antibiofilm, Suppressing < em > Fibronectin Binding Protein A < /em > ( < em > fnba < /em > ) and < em > cna < /em > Virulence Genes, Anti-Inflammatory and Antioxidant Potential of Biosynthesized < em > Solanum lycopersicum < /em > Silver Nanoparticles
Conclusions: The findings from this study indicate that biosynthesized AgNPs from Solanum lycopersicum exhibit promising antimicrobial and antioxidant properties against UTI pathogens, including strains resistant to multiple antibiotics. This suggests their potential as an effective alternative treatment for UTIs. Further research is warranted to fully understand the mechanisms of action and to explore the therapeutic applications of these nanoparticles in combating UTIs.PMID:38541241 | DOI:10.3390/medicina60030515 (Source: Medicina (Kaunas))
Source: Medicina (Kaunas) - March 28, 2024 Category: Universities & Medical Training Authors: Alsayed E Mekky Ahmed E M Abdelaziz Fady Sayed Youssef Shymaa A Elaskary Aly A Shoun Eman A Alwaleed Mahmoud Ali Gaber Abdulaziz A Al-Askar Alhadary M Alsamman Abdullah Yousef Gehad AbdElgayed Reda A Suef Mohamed A Selim Ebrahim Saied Mohamed Khedr Source Type: research

Unravelling the Antimicrobial, Antibiofilm, Suppressing < em > Fibronectin Binding Protein A < /em > ( < em > fnba < /em > ) and < em > cna < /em > Virulence Genes, Anti-Inflammatory and Antioxidant Potential of Biosynthesized < em > Solanum lycopersicum < /em > Silver Nanoparticles
Conclusions: The findings from this study indicate that biosynthesized AgNPs from Solanum lycopersicum exhibit promising antimicrobial and antioxidant properties against UTI pathogens, including strains resistant to multiple antibiotics. This suggests their potential as an effective alternative treatment for UTIs. Further research is warranted to fully understand the mechanisms of action and to explore the therapeutic applications of these nanoparticles in combating UTIs.PMID:38541241 | PMC:PMC10972527 | DOI:10.3390/medicina60030515 (Source: Medicina (Kaunas))
Source: Medicina (Kaunas) - March 28, 2024 Category: Universities & Medical Training Authors: Alsayed E Mekky Ahmed E M Abdelaziz Fady Sayed Youssef Shymaa A Elaskary Aly A Shoun Eman A Alwaleed Mahmoud Ali Gaber Abdulaziz A Al-Askar Alhadary M Alsamman Abdullah Yousef Gehad AbdElgayed Reda A Suef Mohamed A Selim Ebrahim Saied Mohamed Khedr Source Type: research

Unravelling the Antimicrobial, Antibiofilm, Suppressing < em > Fibronectin Binding Protein A < /em > ( < em > fnba < /em > ) and < em > cna < /em > Virulence Genes, Anti-Inflammatory and Antioxidant Potential of Biosynthesized < em > Solanum lycopersicum < /em > Silver Nanoparticles
Conclusions: The findings from this study indicate that biosynthesized AgNPs from Solanum lycopersicum exhibit promising antimicrobial and antioxidant properties against UTI pathogens, including strains resistant to multiple antibiotics. This suggests their potential as an effective alternative treatment for UTIs. Further research is warranted to fully understand the mechanisms of action and to explore the therapeutic applications of these nanoparticles in combating UTIs.PMID:38541241 | PMC:PMC10972527 | DOI:10.3390/medicina60030515 (Source: Medicina (Kaunas))
Source: Medicina (Kaunas) - March 28, 2024 Category: Universities & Medical Training Authors: Alsayed E Mekky Ahmed E M Abdelaziz Fady Sayed Youssef Shymaa A Elaskary Aly A Shoun Eman A Alwaleed Mahmoud Ali Gaber Abdulaziz A Al-Askar Alhadary M Alsamman Abdullah Yousef Gehad AbdElgayed Reda A Suef Mohamed A Selim Ebrahim Saied Mohamed Khedr Source Type: research

Unravelling the Antimicrobial, Antibiofilm, Suppressing < em > Fibronectin Binding Protein A < /em > ( < em > fnba < /em > ) and < em > cna < /em > Virulence Genes, Anti-Inflammatory and Antioxidant Potential of Biosynthesized < em > Solanum lycopersicum < /em > Silver Nanoparticles
Conclusions: The findings from this study indicate that biosynthesized AgNPs from Solanum lycopersicum exhibit promising antimicrobial and antioxidant properties against UTI pathogens, including strains resistant to multiple antibiotics. This suggests their potential as an effective alternative treatment for UTIs. Further research is warranted to fully understand the mechanisms of action and to explore the therapeutic applications of these nanoparticles in combating UTIs.PMID:38541241 | PMC:PMC10972527 | DOI:10.3390/medicina60030515 (Source: Medicina (Kaunas))
Source: Medicina (Kaunas) - March 28, 2024 Category: Universities & Medical Training Authors: Alsayed E Mekky Ahmed E M Abdelaziz Fady Sayed Youssef Shymaa A Elaskary Aly A Shoun Eman A Alwaleed Mahmoud Ali Gaber Abdulaziz A Al-Askar Alhadary M Alsamman Abdullah Yousef Gehad AbdElgayed Reda A Suef Mohamed A Selim Ebrahim Saied Mohamed Khedr Source Type: research

Unravelling the Antimicrobial, Antibiofilm, Suppressing < em > Fibronectin Binding Protein A < /em > ( < em > fnba < /em > ) and < em > cna < /em > Virulence Genes, Anti-Inflammatory and Antioxidant Potential of Biosynthesized < em > Solanum lycopersicum < /em > Silver Nanoparticles
Conclusions: The findings from this study indicate that biosynthesized AgNPs from Solanum lycopersicum exhibit promising antimicrobial and antioxidant properties against UTI pathogens, including strains resistant to multiple antibiotics. This suggests their potential as an effective alternative treatment for UTIs. Further research is warranted to fully understand the mechanisms of action and to explore the therapeutic applications of these nanoparticles in combating UTIs.PMID:38541241 | PMC:PMC10972527 | DOI:10.3390/medicina60030515 (Source: Medicina (Kaunas))
Source: Medicina (Kaunas) - March 28, 2024 Category: Universities & Medical Training Authors: Alsayed E Mekky Ahmed E M Abdelaziz Fady Sayed Youssef Shymaa A Elaskary Aly A Shoun Eman A Alwaleed Mahmoud Ali Gaber Abdulaziz A Al-Askar Alhadary M Alsamman Abdullah Yousef Gehad AbdElgayed Reda A Suef Mohamed A Selim Ebrahim Saied Mohamed Khedr Source Type: research

Unravelling the Antimicrobial, Antibiofilm, Suppressing < em > Fibronectin Binding Protein A < /em > ( < em > fnba < /em > ) and < em > cna < /em > Virulence Genes, Anti-Inflammatory and Antioxidant Potential of Biosynthesized < em > Solanum lycopersicum < /em > Silver Nanoparticles
Conclusions: The findings from this study indicate that biosynthesized AgNPs from Solanum lycopersicum exhibit promising antimicrobial and antioxidant properties against UTI pathogens, including strains resistant to multiple antibiotics. This suggests their potential as an effective alternative treatment for UTIs. Further research is warranted to fully understand the mechanisms of action and to explore the therapeutic applications of these nanoparticles in combating UTIs.PMID:38541241 | PMC:PMC10972527 | DOI:10.3390/medicina60030515 (Source: Medicina (Kaunas))
Source: Medicina (Kaunas) - March 28, 2024 Category: Universities & Medical Training Authors: Alsayed E Mekky Ahmed E M Abdelaziz Fady Sayed Youssef Shymaa A Elaskary Aly A Shoun Eman A Alwaleed Mahmoud Ali Gaber Abdulaziz A Al-Askar Alhadary M Alsamman Abdullah Yousef Gehad AbdElgayed Reda A Suef Mohamed A Selim Ebrahim Saied Mohamed Khedr Source Type: research

Unravelling the Antimicrobial, Antibiofilm, Suppressing < em > Fibronectin Binding Protein A < /em > ( < em > fnba < /em > ) and < em > cna < /em > Virulence Genes, Anti-Inflammatory and Antioxidant Potential of Biosynthesized < em > Solanum lycopersicum < /em > Silver Nanoparticles
Conclusions: The findings from this study indicate that biosynthesized AgNPs from Solanum lycopersicum exhibit promising antimicrobial and antioxidant properties against UTI pathogens, including strains resistant to multiple antibiotics. This suggests their potential as an effective alternative treatment for UTIs. Further research is warranted to fully understand the mechanisms of action and to explore the therapeutic applications of these nanoparticles in combating UTIs.PMID:38541241 | PMC:PMC10972527 | DOI:10.3390/medicina60030515 (Source: Medicina (Kaunas))
Source: Medicina (Kaunas) - March 28, 2024 Category: Universities & Medical Training Authors: Alsayed E Mekky Ahmed E M Abdelaziz Fady Sayed Youssef Shymaa A Elaskary Aly A Shoun Eman A Alwaleed Mahmoud Ali Gaber Abdulaziz A Al-Askar Alhadary M Alsamman Abdullah Yousef Gehad AbdElgayed Reda A Suef Mohamed A Selim Ebrahim Saied Mohamed Khedr Source Type: research

Unravelling the Antimicrobial, Antibiofilm, Suppressing < em > Fibronectin Binding Protein A < /em > ( < em > fnba < /em > ) and < em > cna < /em > Virulence Genes, Anti-Inflammatory and Antioxidant Potential of Biosynthesized < em > Solanum lycopersicum < /em > Silver Nanoparticles
Conclusions: The findings from this study indicate that biosynthesized AgNPs from Solanum lycopersicum exhibit promising antimicrobial and antioxidant properties against UTI pathogens, including strains resistant to multiple antibiotics. This suggests their potential as an effective alternative treatment for UTIs. Further research is warranted to fully understand the mechanisms of action and to explore the therapeutic applications of these nanoparticles in combating UTIs.PMID:38541241 | PMC:PMC10972527 | DOI:10.3390/medicina60030515 (Source: Medicina (Kaunas))
Source: Medicina (Kaunas) - March 28, 2024 Category: Universities & Medical Training Authors: Alsayed E Mekky Ahmed E M Abdelaziz Fady Sayed Youssef Shymaa A Elaskary Aly A Shoun Eman A Alwaleed Mahmoud Ali Gaber Abdulaziz A Al-Askar Alhadary M Alsamman Abdullah Yousef Gehad AbdElgayed Reda A Suef Mohamed A Selim Ebrahim Saied Mohamed Khedr Source Type: research

Unravelling the Antimicrobial, Antibiofilm, Suppressing < em > Fibronectin Binding Protein A < /em > ( < em > fnba < /em > ) and < em > cna < /em > Virulence Genes, Anti-Inflammatory and Antioxidant Potential of Biosynthesized < em > Solanum lycopersicum < /em > Silver Nanoparticles
Conclusions: The findings from this study indicate that biosynthesized AgNPs from Solanum lycopersicum exhibit promising antimicrobial and antioxidant properties against UTI pathogens, including strains resistant to multiple antibiotics. This suggests their potential as an effective alternative treatment for UTIs. Further research is warranted to fully understand the mechanisms of action and to explore the therapeutic applications of these nanoparticles in combating UTIs.PMID:38541241 | PMC:PMC10972527 | DOI:10.3390/medicina60030515 (Source: Medicina (Kaunas))
Source: Medicina (Kaunas) - March 28, 2024 Category: Universities & Medical Training Authors: Alsayed E Mekky Ahmed E M Abdelaziz Fady Sayed Youssef Shymaa A Elaskary Aly A Shoun Eman A Alwaleed Mahmoud Ali Gaber Abdulaziz A Al-Askar Alhadary M Alsamman Abdullah Yousef Gehad AbdElgayed Reda A Suef Mohamed A Selim Ebrahim Saied Mohamed Khedr Source Type: research

Unravelling the Antimicrobial, Antibiofilm, Suppressing < em > Fibronectin Binding Protein A < /em > ( < em > fnba < /em > ) and < em > cna < /em > Virulence Genes, Anti-Inflammatory and Antioxidant Potential of Biosynthesized < em > Solanum lycopersicum < /em > Silver Nanoparticles
Conclusions: The findings from this study indicate that biosynthesized AgNPs from Solanum lycopersicum exhibit promising antimicrobial and antioxidant properties against UTI pathogens, including strains resistant to multiple antibiotics. This suggests their potential as an effective alternative treatment for UTIs. Further research is warranted to fully understand the mechanisms of action and to explore the therapeutic applications of these nanoparticles in combating UTIs.PMID:38541241 | PMC:PMC10972527 | DOI:10.3390/medicina60030515 (Source: Medicina (Kaunas))
Source: Medicina (Kaunas) - March 28, 2024 Category: Universities & Medical Training Authors: Alsayed E Mekky Ahmed E M Abdelaziz Fady Sayed Youssef Shymaa A Elaskary Aly A Shoun Eman A Alwaleed Mahmoud Ali Gaber Abdulaziz A Al-Askar Alhadary M Alsamman Abdullah Yousef Gehad AbdElgayed Reda A Suef Mohamed A Selim Ebrahim Saied Mohamed Khedr Source Type: research

Unravelling the Antimicrobial, Antibiofilm, Suppressing < em > Fibronectin Binding Protein A < /em > ( < em > fnba < /em > ) and < em > cna < /em > Virulence Genes, Anti-Inflammatory and Antioxidant Potential of Biosynthesized < em > Solanum lycopersicum < /em > Silver Nanoparticles
Conclusions: The findings from this study indicate that biosynthesized AgNPs from Solanum lycopersicum exhibit promising antimicrobial and antioxidant properties against UTI pathogens, including strains resistant to multiple antibiotics. This suggests their potential as an effective alternative treatment for UTIs. Further research is warranted to fully understand the mechanisms of action and to explore the therapeutic applications of these nanoparticles in combating UTIs.PMID:38541241 | PMC:PMC10972527 | DOI:10.3390/medicina60030515 (Source: Medicina (Kaunas))
Source: Medicina (Kaunas) - March 28, 2024 Category: Universities & Medical Training Authors: Alsayed E Mekky Ahmed E M Abdelaziz Fady Sayed Youssef Shymaa A Elaskary Aly A Shoun Eman A Alwaleed Mahmoud Ali Gaber Abdulaziz A Al-Askar Alhadary M Alsamman Abdullah Yousef Gehad AbdElgayed Reda A Suef Mohamed A Selim Ebrahim Saied Mohamed Khedr Source Type: research