This Common Supplement Fights Cognitive Decline
This ubiquitous supplement may improve memory and abstract reasoning. (Source: PsyBlog | Psychology Blog)
Source: PsyBlog | Psychology Blog - January 16, 2024 Category: Psychiatry & Psychology Authors: Jeremy Dean Tags: Brain Health Nutrition Source Type: blogs
Six favorite books of 2023 to help harness the stress response and boost resilience, curiosity and wonder
It’s hard to address important issues in our lives or in society if we are stressed, depleted, and isolated. Perhaps that’s why many of 2023’s favorite books offer approaches for real self-care. They focus on how to manage stress, find more happiness in life, seek wonder and inspiration, appreciate art, understand our personal strengths, or change our mindset in healthy ways.
In each of these books, the authors aspire to help us find greater health and happiness as we cope with life in the present, while working toward a healthier, more compassionate world for all.
Tomorrowmind: Thriving at Work—Now and in an Uncer...
Source: SharpBrains - January 16, 2024 Category: Neuroscience Authors: Greater Good Science Center Tags: Brain/ Mental Health Education & Lifelong Learning art Books happiness healthy manage-stress mindful mindset resilience Stress Response workplace Source Type: blogs
A Proteomic Model for Five Subtypes of Alzheimer's Disease
There has been some work in recent years aimed at distinguishing subtypes of Alzheimer's disease that may respond quite differently to therapies. How much of the poor results in clinical trials is a matter of aiming too broadly, at patients who cannot respond well to a specific therapy? Of late, this attempt at categorization has focused on proteomic analyses of patient samples. Here find a paper covering results that were discussed late last year, in which researchers propose that there are five important subtypes of Alzheimer's disease.
Alzheimer's disease (AD) is heterogenous at the molecular level. Understandi...
Source: Fight Aging! - January 16, 2024 Category: Research Authors: Reason Tags: Daily News Source Type: blogs
The Future Of Cognitive Health: This Is How Digital Health Can Help
According to this study, digital healthcare technologies offer ways to manage and slow down the progression of conditions like dementia and mild cognitive impairment. However, choosing the right technology is difficult because there’s no comprehensive review that covers the various types of digital technology for cognitive impairment, including their effects and limitations.
The goal of the study was to identify different types of digital health technologies used for dementia and mild cognitive impairment and evaluate how the results are measured and aligned with their intended purposes.
A total of 13...
Source: The Medical Futurist - January 16, 2024 Category: Information Technology Authors: Andrea Koncz Tags: TMF cognitive health Source Type: blogs
Evidence for the Unfolded Protein Response to be Involved in Age-Related Deafness
Researchers have found that deafness-associated gene TMTC4 causes pathology via an excessive increase in the unfolded protein response in sensory hair cells of the inner ear, and loud noise does much the same. This suggests that inhibition of the unfolded protein response in these cells might be a way to slow loss of hearing capacity, or protect against the effects of loud noise and drugs that can harm hair cells. Still, this isn't a path to restoration of hearing capacity. That would require some way to replace lost hair cells and their connections to the brain.
Mutations to the TMTC4 gene trigger a molecular dom...
Source: Fight Aging! - January 15, 2024 Category: Research Authors: Reason Tags: Daily News Source Type: blogs
Self-management skills we don ’ t often discuss
I’m back from my summer break (I’m in Aotearoa/New Zealand – we shut down over Christmas/New Year just like the US and UK do over July/August!), and I want to begin with a cracker of a topic: medication management!
Now I am not a prescriber. I don’t hold any ability to write prescriptions of any kind, not even exercise ;-). Yet most of the people I’ve seen in clinical practice have started their journey living with pain by being prescribed medications.
All medications have side effects, true effects (well… maybe), adverse effects, and the human factor: taking them in the way that o...
Source: HealthSkills Weblog - January 14, 2024 Category: Anesthesiology Authors: BronnieLennoxThompson Tags: Chronic pain Coping strategies Research Science in practice pain management self-management Therapeutic approaches Source Type: blogs
Two-Thirds Of Severely Depressed Respond To Novel Brain Stimulation Technique (M)
A variation on an FDA approved method of transcranial magnetic stimulation (TMS) for depression doubles its effectiveness. (Source: PsyBlog | Psychology Blog)
Source: PsyBlog | Psychology Blog - January 14, 2024 Category: Psychiatry & Psychology Authors: Jeremy Dean Tags: Depression subscribers-only Source Type: blogs
Fight Aging! Newsletter, January 15th 2024
In conclusion, FMD cycles have high potential to be effective in increasing the toxicity of a range of therapies against ALL and other blood cancers and should be tested in randomized clinical trials, especially in combination with immunotherapy and low toxicity cancer therapies.
In summary, we present a new strategy for improving leukemia treatment by combining FMD with chemotherapy to promote the killing of ALL cells in part by an immune-dependent mechanism. Fasting/FMD has been shown to reduce chemotherapy-associated toxicity in pre-clinical and clinical studies and thus represents a safe and potentially effectiv...
Source: Fight Aging! - January 14, 2024 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Use These 3 Writing Principles to Boost Self-Confidence
How often do you try to persuade people and convey your ideas to others?
For students working on essays or professionals engaging in a debate, it's a regular activity. They know the principles of argumentative writing inside and out, and they use them.
For others, those principles can become an efficient practice to enhance self-confidence. Even when keeping a journal, writing a diary, or practicing reflective essays, you can implement three fundamental principles of argumentative writing to grow communication skills, self-esteem, and attitude toward yourself.
What are these principles? How can you implement them ...
Source: PickTheBrain | Motivation and Self Improvement - January 12, 2024 Category: Consumer Health News Authors: Lesley J. Vos Tags: confidence creativity featured writing tips Source Type: blogs
This Lively Pursuit Beats Cycling And Walking To Keep Your Brain Young
This pursuit slows and can even reverse age-related physical and mental decline. (Source: PsyBlog | Psychology Blog)
Source: PsyBlog | Psychology Blog - January 12, 2024 Category: Psychiatry & Psychology Authors: Jeremy Dean Tags: Dementia Source Type: blogs
Trial By Error: Study Finds “ Elevated Brain Injury Markers and Reduced Grey Matter Volume ” a Year After Hospitalization for COVID-19
By David Tuller, DrPH A British study of neurological sequelae in patients many months after hospitalization for COVID-19 has found that “post acute cognitive deficits…were associated with elevated brain injury markers in serum and reduced grey matter volume,” according to a pre-print posted earlier this week. (A pre-print is a paper that has not yet … Trial By Error: Study Finds “Elevated Brain Injury Markers and Reduced Grey Matter Volume” a Year After Hospitalization for COVID-19 Read More » (Source: virology blog)
Source: virology blog - January 12, 2024 Category: Virology Authors: David Tuller Tags: Uncategorized covid-cns FND Long Covid neurology Source Type: blogs
Amyloid- β Inhibits Synaptic Proteasomal Function in Alzheimer's Disease
Cells contain many proteasomes, one portion of a broad array of repair and quality control mechanisms. The proteasome is a hollow, capped cylindrical structure made of many component proteins. It admits entry only to proteins that have been decorated with the addition of a ubiquitin molecule. Once inside the proteasome's central chamber, the ubiquinated protein is disassembled into short peptides suitable for reuse in the synthesis of other proteins. This ubiquitin-proteasome system is necessary to prevent the buildup of damaged, misfolded, unfolded, or otherwise unwanted proteins.
It has been noted that proteasomal...
Source: Fight Aging! - January 11, 2024 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs
Withings Scales Put Data Daily at the Center of Patient Engagement
Few people want to think about their health all the time, but many of us step on a scale every morning. Antoine Robiliard, vice president of Withings Health Solutions, explores the tensions of this interaction and the potential for making positive changes in patient lives in this video.
Withings’s scales measure much more than weight: some can also report BMI, body composition, and electrochemical skin conductance, which helps diagnose the neuropathies and foot ulcers that are common in people with diabetes. The Body Pro includes a cellular connection so that it can be used by people who lack WiFi connections and mob...
Source: EMR and HIPAA - January 11, 2024 Category: Information Technology Authors: Andy Oram Tags: Clinical Communication and Patient Experience Health IT Company Healthcare IT Hospital - Health System Telemedicine and Remote Monitoring Antoine Robiliard Body Pro Body Pro 2 Connected Scales diabetes Diabetic Monitoring FDA Hea Source Type: blogs
NRF1 is Neuroprotective via Proteasomal Function
Cells maintain themselves against damage and stress via a range of maintenance processes. These include autophagy, in which proteins and structures are transported to the lysosome to be broken down by enzymes, and the ubiquitin-proteasome system, in which specific proteins are dismantled in the proteasome, among others. It is well demonstrated that upregulation of these processes improves resistance to cell stress, and can also improve long-term health, reducing risk of age-related disease and slowing progression of those conditions. Upregulation of autophagy, for example, is a feature of many interventions that modestly s...
Source: Fight Aging! - January 10, 2024 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs
