Predicting the Order of Arrival of the First Rejuvenation Therapies
It has been going on eight years since I last speculated on the order of arrival of the first rejuvenation therapies. Tempus fugit, and time for an updated version! Eight years is a long enough span of time for the first of those rejuvenation therapies to now exist, albeit in a prototypical form, arguably proven in principle but not concretely. The world progresses but my biases remain much the same: the first rejuvenation therapies to work well enough to merit the name will be based on the SENS vision, that aging is at root caused by a few classes of accumulated cell and tissue damage, and biotechnologies that either repa...
Source: Fight Aging! - March 25, 2024 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs

CIO Podcast – Episode 71: Data, Analytics, and AI with Richard Clark, PhD
For the 71st episode of the CIO podcast hosted by Healthcare IT Today, we are joined by Richard Clark, PhD, Senior Vice President and Chief Analytics Officer at Highmark Health to discuss data, analytics, and AI! To kick off this episode, we discuss Clark’s double role working for a payer and provider and how that has allowed him to do things that would otherwise be difficult if he wasn’t. Then we take a look at the use of AI and GenAI and talk about where it is making the most impact in healthcare today and where we think it will make the most impact 3 years from now. Next, Clark shares some tips for what peop...
Source: EMR and HIPAA - March 25, 2024 Category: Information Technology Authors: John Lynn Tags: AI/Machine Learning Analytics/Big Data C-Suite Leadership Healthcare CIO Podcasts Healthcare IT Hospital - Health System IT Infrastructure and Dev Ops AI Solutions CIO Leadership GenAI Google Cloud Healthcare Analytics Healthcare D Source Type: blogs

The Center for Neuroscience and Behavior at American University Presents The Therapeutic Use of Psychedelic Drugs: Legal, Policy and Neuroscientific Perspectives
; 8:00AM – 6:00PM on Friday, April 12th, 2024. The symposium, hosted by the American University Washington College of Law,... (Source: HealthLawProf Blog)
Source: HealthLawProf Blog - March 25, 2024 Category: Medical Law Authors: Katharine Van Tassel Source Type: blogs

Bonus Features – March 24, 2024 – Data infrastructure investments have 124% ROI, 85% of healthcare workers believe AI can improve the patient experience, plus 28 more stories
This article will be a weekly roundup of interesting stories, product announcements, new hires, partnerships, research studies, awards, sales, and more. Because there’s so much happening out there in healthcare IT we aren’t able to cover in our full articles, we still want to make sure you’re informed of all the latest news, announcements, and stories happening to help you better do your job. News and Surveys More than half (52%) of provider organizations use entirely manual workflows for credentialing and network management, according to a survey from Medallion. A survey from Hakkoda found 92% of healthcare organiz...
Source: EMR and HIPAA - March 24, 2024 Category: Information Technology Authors: Brian Eastwood Tags: Healthcare IT Ardent Health Services athenahealth Availity Carta Healthcare Christine Gall Collette Health DrFirst DUOS FOLX Health Forbes Gary L. Harton Gattaca Genomics Gene Scheurer Greg Coticchia Greg Sottolano Hakkoda Source Type: blogs

Fight Aging! Newsletter, March 25th 2024
This study also reports the expansion of satellite cells in human muscle with CR. This finding is critical to suggest translational relevance to the rodent data observed for more than a decade. Moreover, the increased expression of the plasminogen receptor Plg-RKT observed on human satellite cells during CR provided additional support for the theory that our rodent model is relevant to human biology. « Back to Top Interesting Insight into the Relationship Between TP53, Telomerase, and Telomere Length https://www.fightaging.org/archives/2024/03/interesting-insight-into-the-relationship-between-t...
Source: Fight Aging! - March 24, 2024 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Head Up Tilt Test (HUTT)
Transcript of the video: Head up tilt test, is usually done for the evaluation of recurrent syncope. Sometimes, head up tilt test, also known in short as HUTT, is also done for the evaluation of postural orthostatic tachycardia syndrome, POTS, a condition in which there is tachycardia on standing up, without a fall in blood pressure. In usual syncope, there could be a fall in blood pressure, bradycardia, and there are various types, which will be described. There are various protocols for head up tilt test, which are followed in different institutions. Basically you need a tilt-table, in which the person is lying down fir...
Source: Cardiophile MD - March 24, 2024 Category: Cardiology Authors: Johnson Francis Tags: General Cardiology Source Type: blogs

Weekly Roundup – March 23, 2024
Welcome to our Healthcare IT Today Weekly Roundup. Each week, we’ll be providing a look back at the articles we posted and why they’re important to the healthcare IT community. We hope this gives you a chance to catch up on anything you may have missed during the week. Addressing the Billing Cycle With Ambient Clinical Voice. John Lynn talked to Gautamdev Chowdary and Sean Ross at Medvise.AI, which has trained voice-to-text transcription to assign the best ICD or CPT codes and aims to provide fully automated and accurate billing. Read more… A Look at Interesting Innovations at HIMSS 2024. Healthcare IT Today reco...
Source: EMR and HIPAA - March 23, 2024 Category: Information Technology Authors: Brian Eastwood Tags: Healthcare IT Healthcare IT Today Weekly Roundup Source Type: blogs

Transforming Clinical Quality & Value in Rehabilitation with Neurocognitive Technology
The following is a guest article by Jared Gillespie, Senior Director of Clinical Solutions at Academy Medtech Ventures (AMV) In the landscape of rehabilitative care, the integration of neurocognitive technology stands as a beacon of innovation, charting a course toward improved clinical quality and patient outcomes. This journey into the brain’s potential within rehabilitation not only elevates the standard of care but also underscores the role of advanced technologies in shaping the future of healthcare. Traditional rehabilitative care has predominantly focused on physical recovery, often overlooking the brain’...
Source: EMR and HIPAA - March 22, 2024 Category: Information Technology Authors: Guest Author Tags: Clinical Communication and Patient Experience Health IT Company Healthcare IT Hospital - Health System Academy Medtech Ventures AMV Clinical Quality Healthcare Transformation Jared Gillespie Neurocognitive Technology rehabilitative c Source Type: blogs

Thoughts on What is Revealed in the Trial Data for Amyloid- β Clearance
There are now several immunotherapies capable of clearing amyloid-β aggregates from the aging brain, and a sizable amount of clinical trial data to look through. Sadly, this approach doesn't much help patients in the later stages of Alzheimer's disease, but the evidence to date suggests that it may be useful in prevention if the clearance is conducted early enough. Amyloid-β aggregation causes mild cognitive impairment in and of itself, but really just sets the stage for a set of different processes, inflammation and tau aggregation, that drive the late stage of Alzheimer's disease. At that point, clearing amyloid-β mak...
Source: Fight Aging! - March 22, 2024 Category: Research Authors: Reason Tags: Daily News Source Type: blogs

The Longevity-Associated BPIFB4 Variant is Anti-Inflammatory
A variant in the gene BPIFB4 has been found to correlate with longevity in humans. In these matters it is worth noting that even small effects on mortality risk result in noticeable correlations with sustained over decades, and indeed all of the known human associations between longevity and genetic variation identified in large study populations are thought to have only modest effect sizes. What are the underlying mechanisms for BPIFB4, however? Researchers here make an argument for suppression of the chronic inflammation of aging as the reason for the association between BPIFB4 and longevity. Certainly chronic inflammato...
Source: Fight Aging! - March 22, 2024 Category: Research Authors: Reason Tags: Daily News Source Type: blogs

Decoding the Mind: Basic Science Revolutionizes Treatment of Mental Illnesses
In this Director ’s Message guest authored by the Division of Neuroscience and Basic Behavioral Science, learn about NIMH's investments in basic neuroscience, genetics, and behavioral research that have helped improve the diagnosis, treatment, and prevention of mental illnesses. (Source: NIMH Directors Blog)
Source: NIMH Directors Blog - March 21, 2024 Category: Psychiatry Authors: National Institute of Mental Health Source Type: blogs

TDP-43 Pathology May Extend to the Vasculature and Blood-Brain Barrier
TDP-43 is one of a small number of proteins that can become altered in ways that lead to the formation of solid aggregates that, directly and indirectly, cause cell dysfunction and death in the brain. In the case of TDP-43, this proteopathy contributes to amyotrophic lateral sclerosis (ALS), frontotemporal lobar degeneration (FTLD), and what is now called limbic predominant age-related TDP-43 encephalopathy (LATE). This was a more recent discovery than other aggregates involved in neurodegenerative conditions, such as amyloid-β, tau, and α-synuclein, and so the pace of discovery for TDP-43 is a little faster; more remain...
Source: Fight Aging! - March 21, 2024 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs

Low Socioeconomic Status Correlates with Raised Dementia Risk
It is well known that low socioeconomic status correlates with a raised risk of age-related disease and mortality, though it is challenging to determine which of the possible causes are in fact more or less important. A web of correlations are linked to socioeconomic status: intelligence, access to medical services, education, personality traits, lifestyle choices, and more. Here the focus of the study is on location of residence as a marker of socioeconomic status, and in this context it is interesting to note the studies that have compared the differences in particulate air pollution versus mortality in wealthier versus ...
Source: Fight Aging! - March 21, 2024 Category: Research Authors: Reason Tags: Daily News Source Type: blogs

The Vitamin Deficiency That ’ s Putting Your Mental Health At Risk
The deficiency is linked to depression and poorer brain function, lower verbal fluency and even dementia. (Source: PsyBlog | Psychology Blog)
Source: PsyBlog | Psychology Blog - March 20, 2024 Category: Psychiatry & Psychology Authors: Jeremy Dean Tags: Depression Source Type: blogs

Aging Affects the Neural Regulation of Metabolism and Desired Food Intake
Researchers here make an interesting discovery in rats, finding an age-related change in the structure of specific neurons that encourages greater intake of calories and dysfunctional metabolism by suppressing satiation feedback. In rats this mechanism can be manipulated by diet and genetics to alter the pace at which older rats become overweight and metabolically abnormal. As is often the case in research, this discovery is a proximate cause to the problem of metabolic regulation, and it is entirely unclear as to how the deeper mechanisms of aging, such as chronic inflammation, mitochondrial dysfunction, and so forth, are...
Source: Fight Aging! - March 20, 2024 Category: Research Authors: Reason Tags: Daily News Source Type: blogs