Isolation and characterization of lactic acid bacteria producing a potent anti-listerial bacteriocin-like inhibitory substance (BLIS) from chhurpi, a fermented milk product
The objective of this study was to identify lactic acid bacteria (LAB) that produce bacteriocin-like inhibitory substance (BLIS) and have strong anti-listerial activity. We have identified and analyzed a LAB obtained from chhurpi samples, a popular milk-derived product in the Himalayan regions of India and Nepal. The strain was studied and identified based on its morphological, biochemical, and physiological characteristics. Furthermore, the molecular 16s-rDNA analysis suggests that the strain was Lactococcus sp. RGUAM1 (98.2% similar to Lactococcus lactis subsp. hordniae NBRC 100931T). The isolated strain can produce a po...
Source: Archives of Microbiology - January 22, 2024 Category: Microbiology Authors: Atanu Manna Subhas Chandra Jana Source Type: research

Insights on historical milestones of mental health in Nepal: Country profile
Indian J Psychiatry. 2023 Nov;65(11):1122-1128. doi: 10.4103/indianjpsychiatry.indianjpsychiatry_197_23. Epub 2023 Nov 24.ABSTRACTThe present paper has highlighted the mental health development in Nepal. It covers the current state of mental health system and services and a throwback on the significant changes over a period of time. This review grabs a sneak into mental health plan/policies, prevalence; health facilities and human resources, monitoring and supervision, budget allocation, nongovernmental sector involvement, and international agreements. Every description in this paper is substantially based on the progressi...
Source: Indian Journal of Psychiatry - January 22, 2024 Category: Psychiatry Authors: Gayatri Khanal Y Selvamani Prabhat Sapkota Source Type: research

Exploring knowledge, perceptions, and practices of antimicrobials, and their resistance among medicine dispensers and community members in Kavrepalanchok District of Nepal
ConclusionPromoting and strengthening the appropriate use of antimicrobials among medicine dispensers and community members is crucial. Bold policies and collective implementation of regulations could help combat antimicrobial resistance. (Source: PLoS One)
Source: PLoS One - January 19, 2024 Category: Biomedical Science Authors: Sabina Marasini Source Type: research

Assessing Human Development in Nepal through Descriptive and Cluster Analysis: Progress and Disparities
In conclusion, there exists urgent need to cope with human development related issues for formulat ing development policies and strategies in Nepal. (Source: Applied Research in Quality of Life)
Source: Applied Research in Quality of Life - January 19, 2024 Category: International Medicine & Public Health Source Type: research

Association between maternal experiences of intimate partner violence and child stunting: a secondary analysis of the Demographic Health Surveys of four South Asian countries
Conclusion Our study findings suggest that maternal exposure to IPV is associated with child stunting. Further research investigating the relationship between IPV and child outcomes using improved and advanced statistical analyses can provide substantial evidence to enhance public awareness and potentially reduce the burden of child stunting in South Asian countries. (Source: BMJ Open)
Source: BMJ Open - January 19, 2024 Category: General Medicine Authors: Lakhdir, M. P. A., Ambreen, S., Sameen, S., Asim, M., Batool, S., Azam, I., Usmani, B. A., Iqbal, R. Tags: Open access, Global health Source Type: research

Assessing Human Development in Nepal through Descriptive and Cluster Analysis: Progress and Disparities
In conclusion, there exists urgent need to cope with human development related issues for formulat ing development policies and strategies in Nepal. (Source: Applied Research in Quality of Life)
Source: Applied Research in Quality of Life - January 19, 2024 Category: International Medicine & Public Health Source Type: research

& #8220;What Do I Say? How Do I Say it? & #8221; Twitter as a Knowledge Dissemination Tool for Mental Health Research
(Source: Journal of Health Communication)
Source: Journal of Health Communication - January 12, 2024 Category: International Medicine & Public Health Authors: Madden Prior Guckel Garlick Bock Bryant O ’Dean Nepal Ward Thornton Source Type: research

Perceived Burden of Care among Parents of Children with Sickle Cell Disease
CONCLUSIONS: The study showed that the majority of the parents' perceived a mild to moderate burden.PMID:38196207 | DOI:10.33314/jnhrc.v21i02.4575 (Source: Cell Research)
Source: Cell Research - January 10, 2024 Category: Cytology Authors: Saraswoti Nai Uma Devi Ranjitkar Apsara Pandey Source Type: research

Prevalence of Depression and its Associated Factors among Inmates
CONCLUSIONS: More than half of the prisoners have depressive symptoms & thus recommended for the confirmatory diagnosis and treatment of mental issues drawing the attention of concerned authorities toward prisoner's mental health.PMID:38196213 | DOI:10.33314/jnhrc.v21i02.4617 (Source: Cell Research)
Source: Cell Research - January 10, 2024 Category: Cytology Authors: Simran Mahato Nishchal Devkota Birat Raj Kafle Matrika Singh Harsha Raj Dahal Source Type: research

Impact of Case Based Learning on Teaching of Undergraduate Oral Pathology Course
CONCLUSIONS: As case-based learning was positively perceived and preferred along with lectures, an attempt to incorporate it along with lectures in clinically important topics should be made.PMID:38196214 | DOI:10.33314/jnhrc.v21i02.4312 (Source: Cell Research)
Source: Cell Research - January 10, 2024 Category: Cytology Authors: Bijayata Shrestha Sushil Subedi Sabita Paudel Nuwadutta Subedi Umesh Parajuli Source Type: research

COVID-19 vaccine prediction based on an interpretable CNN-LSTM model with three-stage feature engineering
ConclusionThe interpretability of the CNN-LSTM model is a key aspect considered in this research to explain the prediction results. The model ’s interpretability aims to identify important features affecting the prediction results and provide government and vaccine companies with guidelines in the decision-making for vaccine supply planning in developing countries.Graphical Abstract (Source: Health and Technology)
Source: Health and Technology - January 9, 2024 Category: Information Technology Source Type: research

Publisher Correction: Harnessing a decade of research at the Research Institute for Bioscience and Biotechnology in Kathmandu, Nepal: Proceedings of the Fourth International Conference ICBB-2022
(Source: BMC Proceedings)
Source: BMC Proceedings - January 9, 2024 Category: Biomedical Science Source Type: research

Participatory policy analysis in health policy and systems research: reflections from a study in Nepal
Participatory policy analysis (PPA) as a method in health policy and system research remains underexplored. Using our experiences of conducting PPA workshops in Nepal to explore the impact of the country ’s mov... (Source: Health Research Policy and Systems)
Source: Health Research Policy and Systems - January 9, 2024 Category: International Medicine & Public Health Authors: Sujata Sapkota, Simon Rushton, Edwin van Teijlingen, Madhusudan Subedi, Julie Balen, Sujan Gautam, Pratik Adhikary, Padam Simkhada, Sharada P. Wasti, Jiban K. Karki, Sarita Panday, Alisha Karki, Barsha Rijal, Saugat Joshi, Srijana Basnet and Sujan B. Mara Tags: Opinion Source Type: research

COVID-19 vaccine prediction based on an interpretable CNN-LSTM model with three-stage feature engineering
ConclusionThe interpretability of the CNN-LSTM model is a key aspect considered in this research to explain the prediction results. The model ’s interpretability aims to identify important features affecting the prediction results and provide government and vaccine companies with guidelines in the decision-making for vaccine supply planning in developing countries.Graphical Abstract (Source: Health and Technology)
Source: Health and Technology - January 9, 2024 Category: Information Technology Source Type: research

A Retrospective Study Comparing the Effect of Conventional Coagulation Parameters Vs. Thromboelastography-Guided Blood Product Utilization in Patients With Major Gastrointestinal Bleeding
CONCLUSION: This study revealed that TEG is not superior to conventional coagulation parameters in limiting the volume of blood product transfusion in major GIB patients in ICU settings.PMID:38189039 | PMC:PMC10769601 | DOI:10.14740/jocmr5022 (Source: Clin Med Res)
Source: Clin Med Res - January 8, 2024 Category: Research Authors: Chhabindra Nepal Ojbindra Kc Manisha Koirala Ananta Subedi Rakshya Sharma Srinadh Annangi Suha Jabak Said Chaaban Source Type: research