Assessment of skin sensitizing potential of metals with & #946;-galactosidase-expressing E. coli culture system
(Source: Journal of Toxicology and Environmental Health Part A)
Source: Journal of Toxicology and Environmental Health Part A - October 28, 2019 Category: Environmental Health Authors: Nepal Kim Cha Jeong Source Type: research

Effect of skill drills on neonatal ventilation performance in a simulated setting- observation study in Nepal
Maintaining neonatal resuscitation skills among health workers in low resource settings will require continuous quality improvement efforts. We aimed to evaluate the effect of skill drills and feedback on neon... (Source: BMC Pediatrics)
Source: BMC Pediatrics - October 28, 2019 Category: Pediatrics Authors: Rejina Gurung, Abhishek Gurung, Avinash K. Sunny, Omkar Basnet, Shree Krishna Shrestha, Øystein Herwig Gomo, Helge Myklebust, Sakina Girnary and Ashish KC Tags: Research article Source Type: research

Type Va extrahepatic bile duct duplication: a case report
ConclusionA rare case of double common bile duct (type Va) complicated by choledocholithiasis, cholangitis, and chronic cholecystitis is reported here. Rare cases are sometimes overlooked by modern diagnostic techniques. Correct diagnosis helps appropriate surgical intervention. (Source: Journal of Medical Case Reports)
Source: Journal of Medical Case Reports - October 28, 2019 Category: General Medicine Source Type: research

Burden of Shigella spp and Vibrio spp, and their antibiotic sensitivity pattern in the patients with acute gastroenteritis in tertiary care hospital in Nepal
The present study aims to investigate the etiology, clinical profile and resistance pattern of the isolated pathogens in Nepalese adults with acute gastroenteritis. This cross-sectional study was conducted at ... (Source: BMC Research Notes)
Source: BMC Research Notes - October 26, 2019 Category: Research Authors: Shiv Kumar Sah, Shreejana Basnet, Sushma Shrestha, Kusum Ghale, Sabita Tamang, Dipendra Kumar Mandal and Sher Bahadur Pun Tags: Research note Source Type: research

Molecular phylogenetics of black cobra (Naja naja) in Pakistan
ConclusionIt was confirmed genetically that there are two cobra species i.e., black and brown cobras in Pakistan. The study will not only help in genetic conservation but also in developing the anti-venom against snake species. (Source: Electronic Journal of Biotechnology)
Source: Electronic Journal of Biotechnology - October 25, 2019 Category: Biotechnology Source Type: research

IJERPH, Vol. 16, Pages 4114: Air-Quality Assessment of On-Site Brick-Kiln Worker Housing in Bhaktapur, Nepal: Chemical Speciation of Indoor and Outdoor PM2.5 Pollution
This study characterized non-occupational exposure to PM2.5 by comparing overall concentrations and specific chemical components of PM2.5 inside and outside of brick workers’ on-site housing. For all samples, the geometric mean PM2.5 concentration was 184.65 μg/m3 (95% confidence interval: 134.70, 253.12 μg/m3). PM2.5 concentrations differed by kiln number (p = 0.009). Kiln number was significantly associated with 16 of 29 (55%) air pollutant, temperature, or relative humidity variables. There was not a significant interaction between kiln number and location of sample for PM2.5 (p = 0.1...
Source: International Journal of Environmental Research and Public Health - October 25, 2019 Category: Environmental Health Authors: Steven M. Thygerson John D. Beard Marion J. House Rilee L. Smith Hunter C. Burbidge Kathryn N. Andrus Frank X. Weber Ryan Chartier James D. Johnston Tags: Article Source Type: research

Revisiting: “A pre-post study of a multi-country scale up of resuscitation training of facility birth attendants: does helping babies breathe training save lives?”
Helping Babies Breathe (HBB) is a low cost, skills-based neonatal resuscitation education program designed specifically for use in low resource settings. Studies from Tanzania, India and Nepal have demonstrate... (Source: BMC Pregnancy and Childbirth)
Source: BMC Pregnancy and Childbirth - October 24, 2019 Category: OBGYN Authors: Sara Berkelhamer and Nalini Singhal Tags: Correspondence Source Type: research

Insomnia and its associated factors among  older people of selected ward of Banepa municipality, Nepal
AbstractAimsThe aim of this study was to calculate the prevalence of insomnia and identify the factors associated with it among older people of Banepa Municipality, Province No.3 of Nepal.DesignA quantitative descriptive cross ‐sectional study was done; data were collected for three months from September–November 2018.MethodsOne hundred and fourteen older people were recruited. The data were collected through a structured interview questionnaire that included socio ‐demographic characteristics and Nepalese version of standard Pittsburgh Insomnia Rating Scale (20‐item version). Information on general health cond...
Source: Nursing Open - October 23, 2019 Category: Nursing Authors: Manisha Dangol, Sunil Shrestha, Sita Kumari Rai Koirala Tags: RESEARCH ARTICLE Source Type: research

Prevalence and determinants of frailty in the absence of disability among older population: a cross sectional study from rural communities in Nepal
Longevity and frailty have significant implications for healthcare delivery. They increase demands for healthcare service and surge risk of hospitalization. Despite gaining global attention, determinants of fr... (Source: BMC Geriatrics)
Source: BMC Geriatrics - October 22, 2019 Category: Geriatrics Authors: Uday Narayan Yadav, Man Kumar Tamang, Tarka Bahadur Thapa, Hassan Hosseinzadeh, Mark Fort Harris and Krishna Kumar Yadav Tags: Research article Source Type: research

The power of peers: an effectiveness evaluation of a cluster-controlled trial of group antenatal care in rural Nepal
Reducing the maternal mortality ratio to less than 70 per 100,000 live births globally is one of the Sustainable Development Goals. Approximately 830 women die from pregnancy- or childbirth-related complicatio... (Source: Reproductive Health)
Source: Reproductive Health - October 22, 2019 Category: OBGYN Authors: Poshan Thapa, Alex Harsha Bangura, Isha Nirola, David Citrin, Bishal Belbase, Bhawana Bogati, B. K. Nirmala, Sonu Khadka, Lal Kunwar, Scott Halliday, Nandini Choudhury, Al Ozonoff, Jasmine Tenpa, Ryan Schwarz, Mukesh Adhikari, S. P. Kalaunee & hellip; Tags: Research Source Type: research

Perception of the learning environment among the students in a nursing college in Eastern Nepal
Learning environment is an important base for learning processes of students and for preferences of future workplaces. It is considered as an essential factor in determining the success of an effective curricu... (Source: BMC Medical Education)
Source: BMC Medical Education - October 21, 2019 Category: Universities & Medical Training Authors: Erina Shrestha, Ram Sharan Mehta, Gayanand Mandal, Kriti Chaudhary and Nirmala Pradhan Tags: Research article Source Type: research

IJERPH, Vol. 16, Pages 3996: Knowledge, Attitude, and Practice Associated with Antibiotic Use among University Students: A Survey in Nepal
ng Liu Hao Li The purpose of this study was to conduct a preliminary study to assess knowledge, attitude, and practice (KAP) associated with antibiotic use among medical students (MS) and non-medical students (NMS) at Kathmandu University, Nepal. A self-administered questionnaire was distributed to 1223 students for a cross-sectional study. In total, 1222 questionnaires collected from 609 MS and 613 NMS were regarded as effective. A t-test and Chi-square test were applied to analyze the data. A total of 25 out of 39 questions in the KAP survey were found to have statistical significance. The MS showed higher levels o...
Source: International Journal of Environmental Research and Public Health - October 18, 2019 Category: Environmental Health Authors: Poonam Shah Rajeev Shrestha Zongfu Mao Yilin Chen Yan Chen Pramesh Koju Xinliang Liu Hao Li Tags: Article Source Type: research

A missed opportunity: birth registration coverage is lagging behind Bacillus Calmette-Gu érin (BCG) immunization coverage and maternal health services utilization in low- and lower middle-income countries.
CONCLUSION: The gap between birth registration and immunization coverage in low- and lower middle-income countries suggests the potential for leveraging immunization programs to increase birth registration rates. Engaging health providers during the antenatal, delivery, and postpartum periods to increase birth registration may be a useful strategy in countries with access to skilled providers. PMID: 31627761 [PubMed - in process] (Source: Journal of Health, Population, and Nutrition)
Source: Journal of Health, Population, and Nutrition - October 18, 2019 Category: International Medicine & Public Health Authors: Rahman MH, Cox AB, Mills SL Tags: J Health Popul Nutr Source Type: research

IJERPH, Vol. 16, Pages 3965: Assessment of Socio-Demographic Factors, Mother and Child Health Status, Water, Sanitation, and Hygienic Conditions Existing in a Hilly Rural Village of Nepal
Song Lee Mogasale Ahn In many low income developing countries, socioeconomic, environmental and demographic factors have been linked to around half of the disease related deaths that occur each year. The aim of this study is to investigate the sociodemographic factors, mother and child health status, water, sanitation, and hygienic conditions of a Nepalese community residing in a hilly rural village, and to identify factors associated with mother and child health status and the occurrence of diarrheal and febrile disease. A community-based cross-sectional survey was carried out and 315 households from the vill...
Source: International Journal of Environmental Research and Public Health - October 17, 2019 Category: Environmental Health Authors: Bhandari Bak Lee Chon Bhattachan Rimal Shrestha Bhandari Moon Wu Chu Song Lee Mogasale Ahn Tags: Article Source Type: research

ISC1, a new Leishmania donovani population emerging in the Indian sub-continent: Vector competence of Phlebotomus argentipes.
Abstract Visceral leishmaniasis (VL), the most severe form of the disease, is caused by Leishmania donovani in the Indian sub-continent (ISC). Whole genome sequencing studies revealed that two parasite populations exist in the ISC: a main population named the Core Group (CG) found mostly in the lowlands, and a new, genetically different subpopulation called ISC1. Parasites belonging to the CG were shown to be responsible for the recent epidemics, while the ISC1 variant was originally identified in hilly districts of Nepal and was later on increasingly found in the lowlands. Importantly, the ISC1 and CG isolates di...
Source: Infection, Genetics and Evolution - October 17, 2019 Category: Genetics & Stem Cells Authors: Seblova V, Dujardin JC, Rijal S, Domagalska M, Volf P Tags: Infect Genet Evol Source Type: research

Experiences with pain of early medical abortion: qualitative results from Nepal, South Africa, and Vietnam
Medical abortion (MA) has become an increasingly popular choice for women even where surgical abortion services are available. Pain is often cited by women as one of the worst aspects of the MA experience, yet... (Source: BMC Women's Health)
Source: BMC Women's Health - October 15, 2019 Category: OBGYN Authors: Daniel Grossman, Sarah Raifman, Tshegofatso Bessenaar, Lan Dung Duong, Anand Tamang and Monica V. Dragoman Tags: Research article Source Type: research

Detection of Pan drug resistance OXA-48 producing Providencia in an ICU patient for the first time in Nepal
ConclusionsCarbapenamase production along with intrinsic colistin resistance in infecting bacterial pathogens can cause fatal outcomes in the resource limited countries like Nepal where new antibiotic combinations ceftazidime+ Avibactam, or aztreonam +avibactam are not available. Drug resistance patterns including OXA 48 producer should be characterized in all cases by standard phenotypic methods or by Xpert Carba-R assay and larger studies are required to know the exact burden of OXA 48 producer in Nepal. (Source: Antimicrobial Resistance and Infection Control)
Source: Antimicrobial Resistance and Infection Control - October 15, 2019 Category: Infectious Diseases Source Type: research

The burden of and factors associated with misclassification of intrapartum stillbirth: evidence from a large scale multi ‐centric observational study
We examined the misclassification of documented intrapartum stillbirth and factors associated with misclassification.Material and methodsA prospective observational study was performed in 12 public hospitals in Nepal. Data was extracted from the medical records of all births that occurred during six ‐month period of the study. For the study purpose, we classified birth outcome based on the presence of fetal heart sound (FHS) at admission and use of neonatal resuscitation. The health worker documented Intrapartum stillbirths were considered potentially misclassified when there were FHS present at admission and no resuscit...
Source: Acta Obstetricia et Gynecologica Scandinavica - October 10, 2019 Category: OBGYN Authors: KC Ashish, Sara Berkelhamer, Rejina Gurung, Zhou Hong, Haijun Wang, Avinash K Sunny, Pratikysha Bhattarai, Pragya Gautam Poudel, Helena Litorp Tags: ORIGINAL RESEARCH ARTICLE Source Type: research

Disruption, changes, and adaptation: Experiences with chronic conditions in Mozambique, Nepal and Peru
. (Source: Global Public Health)
Source: Global Public Health - October 9, 2019 Category: International Medicine & Public Health Authors: Maria Amalia Pesantes Claire Somerville Suman Bahadur Singh Silvana Perez-Leon Tavares Madede Suzanne Suggs David Beran Source Type: research

The troubled path to food sovereignty in Nepal: ambiguities in agricultural policy reform
AbstractThe food sovereignty movement arose as a challenge to neoliberal models of agriculture and food and the corporatization of agriculture, which is claimed to have undermined peasant agriculture and sustainability. However, food sovereignty is an ambiguous idea. Yet, a few countries are institutionalizing it. In this paper, we argue that food sovereignty possesses the attributes of a ‘coalition magnet’ and, thus, brings together policy actors that support agricultural reform, but have diverse and often opposing interests, in a loose coalition. This facilitates agenda setting, but there may be problems in p...
Source: Agriculture and Human Values - October 5, 2019 Category: Food Science Source Type: research

Neopicrorhiza scrophulariiflora (Pennell) Hong: A comprehensive review of its traditional uses, phytochemistry, pharmacology and safety
ConclusionN. scrophulariiflora is valuable medicinal plant that can serve as promising source of non-harmful and potential medicinal herbal remedies for human beings.Graphical abstract (Source: Journal of Ethnopharmacology)
Source: Journal of Ethnopharmacology - October 4, 2019 Category: Drugs & Pharmacology Source Type: research

Detection of extended-spectrum beta-lactamase-producing E. coli and Klebsiella spp. in effluents of different hospitals sewage in Biratnagar, Nepal
This study was aimed to determine prevalence and resistance pattern like multidrug resistant (MDR) or ESBL nature of E. coli and Klebsiella spp. from various sewage drain samples with an idea to deliver baseline ... (Source: BMC Research Notes)
Source: BMC Research Notes - October 4, 2019 Category: Research Authors: Sanjay Mahato, Ajay Mahato, Elina Pokharel and Ankita Tamrakar Tags: Research note Source Type: research

IJERPH, Vol. 16, Pages 3750: Feasibility Study of a Menstrual Hygiene Management Intervention for People with Intellectual Impairments and Their Carers in Nepal
Conclusion: Within the sample, the Bishesta campaign appears to be a feasible intervention to ensure that one of the groups most vulnerable to exclusion from MHM interventions is not left behind. (Source: International Journal of Environmental Research and Public Health)
Source: International Journal of Environmental Research and Public Health - October 4, 2019 Category: Environmental Health Authors: Jane Wilbur Th érèse Mahon Belen Torondel Shaffa Hameed Hannah Kuper Tags: Article Source Type: research

Effectiveness of health promotion regarding diet and physical activity among Nepalese mothers and their young children: The Heart-health Associated Research, Dissemination, and Intervention in the Community (HARDIC) trial.
Conclusions: Our intervention improves KAP scores regarding diet and physical activity and shows potential for expansion via community health workers, volunteers, and/or local women. Moreover, HARDIC can contribute to Nepal's Package of Essential Noncommunicable Diseases Initiative, which currently lacks a specific package for health promotion. PMID: 31573416 [PubMed - in process] (Source: Global Health Action)
Source: Global Health Action - October 3, 2019 Category: International Medicine & Public Health Tags: Glob Health Action Source Type: research

Morphology, Incidence of Bridging, Dimensions of Sella Turcica, and Cephalometric Standards in Three Different Racial Groups
This study aims to assess the morphological appearance, incidence of bridging, linear dimensions of sella turcica and establish cephalometric standards in Bosnian, Chinese and Nepalese subjects. This retrospective study examined digital standardized lateral cephalograms of 540 subjects, which consisted of 116 females and 64 males with an age range of 8 to 28 years. The sella morphology, bridging, and size were analyzed on the lateral cephalograms. Steiner's and Rickett's analyses were performed on 270 subjects. Sella turcica presented a normal morphology in most Bosnian (86.7%), and Nepalese (90%) subjects whereas flat-sha...
Source: Journal of Craniofacial Surgery - October 1, 2019 Category: Surgery Tags: Original Articles Source Type: research

Correlates of Problematic Internet Use among college and university students in eight countries: An international cross-sectional study.
CONCLUSIONS: The PIU is an important emerging mental health condition among college/university going young adults, with psychological distress being the strongest and most stable correlate of PIU across different countries and cultures in this study. The present study highlighted the importance of screening university and college students for PIU. PMID: 31563832 [PubMed - as supplied by publisher] (Source: Asian Journal of Psychiatry)
Source: Asian Journal of Psychiatry - September 30, 2019 Category: Psychiatry Tags: Asian J Psychiatr Source Type: research

Association between Lys198Asn polymorphism of endothelin ‐1 gene and ischemic stroke: A meta‐analysis
Endothelin (ET) ‐1 is a potent vasoconstrictor peptide produced by endothelial cells and associated with vascular dysfunction and cardiovascular disease. Lys198Asn is a single‐nucleotide polymorphism of gene encoding ET‐1 (EDN1). It is hypothesized that it might have a role in altering ET‐1 and ultimately l eading to vascular dysfunction and ischemic stroke. We therefore conducted a meta‐analysis to investigate the association between Lys198Asn polymorphism of EDN1 and susceptibility of ischemic stroke. The present meta‐analysis suggests that Lys198Asn polymorphism of EDN1 gene is associated with an i...
Source: Brain and Behavior - September 30, 2019 Category: Neurology Authors: Gaurav Nepal, Rajeev Ojha, Hari Prasad Dulal, Binod Kumar Yadav Tags: ORIGINAL RESEARCH Source Type: research

Prevalence of glue ‐sniffing among street children
ConclusionsThey have deprived children and denied not only of their rights as children but also of their normal childhood. Without guidance, education and security, they are heading towards an uncertain future. They can have enough potentiality and talent if they are brought into a better environment and might have real hope for the bright future. (Source: Nursing Open)
Source: Nursing Open - September 30, 2019 Category: Nursing Authors: Sanjay Kumar Sah, Nira Neupane, Anupama Pradhan (Thaiba), Sabita Shah, Asha Sharma Tags: RESEARCH ARTICLE Source Type: research

Pulmonary cryptococcosis: report of the first confirmed autochthonous case in Nepal.
We report a case of cryptococcal pneumonia in a 53 years old female Nepali patient with uncontrolled diabetes mellitus type 2 who empirically received multiple broad-spectrum antibiotics and standard anti-tubercular treatment as well as glucocorticosteroids for suspected sarcoidosis before the diagnosis was finally established. To our knowledge, this is the first confirmed autochthonous case of cryptococcosis reported from Nepal. PMID: 31580849 [PubMed - as supplied by publisher] (Source: Acta Tropica)
Source: Acta Tropica - September 30, 2019 Category: Infectious Diseases Authors: Sah R, Jaiswal A, Singla S, Prakash AK, Mittal SK, Aggarwal A, Singh S, Neupane S, Sah S, Sah R, Neumayr A Tags: Acta Trop Source Type: research

Desmoplastic Infantile Ganglioglioma Masquerading as an Arachnoid Cyst.
We report a case of DIG in a three-month-old boy who presented to our pediatric emergency department with decreased activity and excessive crying. This case report highlights the computed tomography (CT) and magnetic resonance imaging (MRI) findings of this rare tumor. Non-contrast CT scan findings in our case initially masqueraded as an extra-axial arachnoid cyst; however, the MRI findings after contrast agent administration were typical for the diagnosis of DIG. PMID: 31555425 [PubMed] (Source: Oman Medical Journal)
Source: Oman Medical Journal - September 28, 2019 Category: Middle East Health Tags: Oman Med J Source Type: research

A hyperendemic focus of porcine cystic echinococcosis in the Banke District of Nepal.
Abstract Detailed post mortem analyses of 68 free-ranging, slaughter-age pigs from two sites in the Banke District of Nepal identified 36% as being infected with Echinococcus granulosus. The cysts ranged from infertile, immature cysts a few millimetres in diameter to fertile cysts>10 centimetres in diameter. PCR RFLP and DNA sequencing identified the cysts as being E. granulosus sensu stricto. The Banke district has recently been identified as having a high prevalence of porcine cysticercosis. These data suggest that cestode zoonoses in this, and possibly other parts of Nepal may be a serious concern for human ...
Source: Acta Tropica - September 28, 2019 Category: Infectious Diseases Authors: Donadeu M, Gauci CG, Poudel I, Sah K, Singh DK, Jabbar A, Lightowlers MW Tags: Acta Trop Source Type: research

Older people's satisfaction with and utilisation patterns of the Old Age Allowance in Nepal.
CONCLUSION: The Old Age Allowance is a necessary and important contribution to keeping older people connected with family and community. PMID: 31560159 [PubMed - as supplied by publisher] (Source: Australasian Journal on Ageing)
Source: Australasian Journal on Ageing - September 27, 2019 Category: Geriatrics Authors: Dhungana GP, Sapkota M, Bista B Tags: Australas J Ageing Source Type: research

Nardostachys jatamansi (D.Don) DC.-Challenges and opportunities of harnessing the untapped medicinal plant from the Himalayas
ConclusionsAnalysis of various studies revealed a confusion about the botanical nomenclature of the plants and their geographical distributions. Absence of proper markers for identification of correct samples and improperly conducted studies on N. jatamansi were found to be the major hurdles to the use of ethnobotanical information and research findings into applications for human health. Development of markers using molecular, chemical and pharmacognosy based approaches for plant authentication and, in vitro propagation of authenticated material for easy availability of genuine plant material are the possible solutions to...
Source: Journal of Ethnopharmacology - September 25, 2019 Category: Drugs & Pharmacology Source Type: research

IJERPH, Vol. 16, Pages 3571: Incidence and Risk Factors of Pre-Eclampsia in the Paropakar Maternity and Women ’s Hospital, Nepal: A Retrospective Study
This study aims to determine the incidence of pre-eclampsia and distribution of risk factors of pre-eclampsia at Paropakar Maternity and Women’s Hospital, Kathmandu, Nepal. A retrospective study included 4820 pregnant women from 17 September to 18 December 2017. Data were obtained from the medical records of the hospital’s Statistics Department. Associations between the risk factors and pre-eclampsia were determined using logistic regression analysis and expressed as odds ratios. The incidence rate of pre-eclampsia in the study population was 1.8%. Higher incidence of pre-eclampsia was observed ...
Source: International Journal of Environmental Research and Public Health - September 24, 2019 Category: Environmental Health Authors: Seema Das Rupesh Das Rashmita Bajracharya Gehanath Baral Bina Jabegu Jon Øyvind Odland Maria Lisa Odland Tags: Article Source Type: research

The role of social audit as a social accountability mechanism for strengthening governance and service delivery in the primary health care setting of Nepal: a qualitative study
. (Source: Critical Public Health)
Source: Critical Public Health - September 23, 2019 Category: International Medicine & Public Health Authors: Gagan Gurung Sarah Derrett Philip C. Hill Robin Gauld Source Type: research

Multisectoral community development in Nepal has greater effects on child growth and diet than nutrition education alone.
CONCLUSIONS: In this longitudinal study, a comprehensive multisectoral intervention was more successful in improving key growth indicators as well as diet quality in young children. Provision of training in livestock management and nutrition education alone had limited effect on these outcomes. Although more time-consuming and costly to administer, incorporating nutrition training with community social capital development was associated with better child growth and nutrition outcomes than isolated training programmes alone. PMID: 31544735 [PubMed - as supplied by publisher] (Source: Public Health Nutrition)
Source: Public Health Nutrition - September 23, 2019 Category: International Medicine & Public Health Authors: Miller LC, Neupane S, Joshi N, Lohani M, Rogers BL, Neupane S, Ghosh S, Webb P Tags: Public Health Nutr Source Type: research

The role of social audit as a social accountability mechanism for strengthening governance and service delivery in the primary health care setting of Nepal: a qualitative study
. (Source: Critical Public Health)
Source: Critical Public Health - September 23, 2019 Category: International Medicine & Public Health Authors: Gagan Gurung Sarah Derrett Philip C. Hill Robin Gauld Source Type: research

Social and Cultural Factors Leading to Suicide Attempt via Organophosphate Poisoning in Nepal.
Authors: Licata C, Liu L, Mole D, Thorp J, Chand R, Chaulagain S Abstract Organophosphates are commonly used in rural, agricultural communities worldwide. Poisoning in Nepal is commonly a result of suicide attempt via ingestion with a mortality rate of 41 times higher than in the United States even after appropriate treatment. The patient discussed in this case is a 46-year-old Nepalese female with a complicated psychosocial history that presented with a suicide attempt via organophosphate ingestion. She required higher doses and greater lengths of treatment of atropine and pralidoxime to resolve symptoms of toxici...
Source: Case Reports in Psychiatry - September 20, 2019 Category: Psychiatry Tags: Case Rep Psychiatry Source Type: research

Early outcome of Frey ’s procedure for chronic pancreatitis: Nepalese tertiary center experience
Chronic pancreatitis is a progressive and persistent inflammatory disease resulting in pancreatic insufficiency leading to diabetes and steatorrhea. Abdominal pain is the most debilitating feature and is often... (Source: BMC Surgery)
Source: BMC Surgery - September 18, 2019 Category: Surgery Authors: Dhruba Narayan Sah, Ramesh Singh Bhandari, Yogendra Prasad Singh, Pradeep Vaidya, Prasan B. S. Kansakar, Bikal Ghimire, Bishnu Kandel, Jayant Kumar Sah and Paleswan Joshi Lakhey Tags: Research article Source Type: research

Cost-effectiveness and budget impact of the community-based management of hypertension in Nepal study (COBIN): a retrospective analysis
Publication date: October 2019Source: The Lancet Global Health, Volume 7, Issue 10Author(s): Anirudh Krishnan, Eric Andrew Finkelstein, Per Kallestrup, Arjun Karki, Michael Hecht Olsen, Dinesh NeupaneSummaryBackgroundThe greatest risk factor for cardiovascular disease is hypertension, which can be alleviated via diet, exercise, and adherence to medication. Yet, blood pressure control in Nepal is inadequate, which is partly hindered by a lack of evidence-based, low-cost, scalable, and cost-effective cardiovascular disease prevention programmes. The the community-based management of hypertension in Nepal (COBIN) study was a ...
Source: The Lancet Global Health - September 18, 2019 Category: International Medicine & Public Health Source Type: research

Nardostachys jatamansi (D.Don) DC.-Challenges and opportunities for harnessing the untapped medicinal plant from the Himalayas
ConclusionsAnalysis of various studies revealed a confusion about the botanical nomenclature of the plants and their geographical distributions. Absence of proper markers for identification of correct samples and improperly conducted studies on N. jatamansi were found to be the major hurdles to the use of ethnobotanical information and research findings into applications for human health. Development of markers using molecular, chemical and pharmacognosy based approaches for plant authentication and, in vitro propagation of authenticated material for easy availability of genuine plant material are the possible solutions to...
Source: Journal of Ethnopharmacology - September 17, 2019 Category: Drugs & Pharmacology Source Type: research

Acquisition of class C β-lactamase PAC-1 by ST664 strains of Pseudomonas aeruginosa.
Acquisition of class C β-lactamase PAC-1 by ST664 strains of Pseudomonas aeruginosa. Antimicrob Agents Chemother. 2019 Sep 16;: Authors: Bour M, Fournier D, Jové T, Pouzol A, Miltgen G, Janvier F, Jeannot K, Plésiat P Abstract Four ST664 (serotype O:5) strains of Pseudomonas aeruginosa highly resistant to antibiotics including ceftolozane/tazobactam and ceftazidime/avibactam but susceptible to colistin, were found to harbor the rare class C β-lactamase PAC-1 encoding gene on a chromosomally-located Tn1721-like transposon. Gene bla PAC-1 was associated with the 16S rRNA methylas...
Source: Antimicrobial Agents and Chemotherapy - September 16, 2019 Category: Microbiology Authors: Bour M, Fournier D, Jové T, Pouzol A, Miltgen G, Janvier F, Jeannot K, Plésiat P Tags: Antimicrob Agents Chemother Source Type: research

Assessing the effect of climate factors on childhood diarrhoea burden in Kathmandu, Nepal.
CONCLUSION: It is estimated that there exists a significant association (p 
Source: International Journal of Hygiene and Environmental health - September 16, 2019 Category: Environmental Health Authors: Bhandari D, Bi P, Sherchand JB, Dhimal M, Hanson-Easey S Tags: Int J Hyg Environ Health Source Type: research

Bietti's crystalline dystrophy in Nepalese patients: when genetic analysis supports clinical diagnosis.
Authors: Suwal B, Bajimaya S, Bernstein PS PMID: 31512983 [PubMed - as supplied by publisher] (Source: Ophthalmic Genetics)
Source: Ophthalmic Genetics - September 14, 2019 Category: Opthalmology Tags: Ophthalmic Genet Source Type: research

Effect of altitude on urinary, plasma and nail fluoride levels in children and adults in Nepal
This study, for the first time, examined several aspects of fluoride metabolism in children, aged 4-5 years, and their parent, living at lower altitude (1487) areas in Nepal.MethodsThe study assessed total daily fluoride intake (TDFI), 24 h urinary fluoride excretion (UFE), and fluoride concentrations of toe- and finger-nail (FCtoenail, FCfingernail) in children and parents as well as fluoride concentration of plasma (FCplasma) in parents. Fractional urinary fluoride excretion (FUFE) was calculated as the ratio between UFE and TDFI. FCtoenail, FCfingernail and FCplasma were normalised for TDFI by dividing the...
Source: Journal of Trace Elements in Medicine and Biology - September 13, 2019 Category: Biochemistry Source Type: research

A case of high altitude cutaneous leishmaniasis in a non-endemic region in Nepal
Publication date: Available online 11 September 2019Source: Parasitology InternationalAuthor(s): Anup Bastola, Mitesh Shrestha, Mahesh Lamsal, Srijan Shrestha, Sabita Prajapati, Anurag Adhikari, Birendra Prasad Gupta, Mallorie Hide, Lina Devkota, Bimal Sharma Chalise, Kishor Pandey, Krishna Das ManandharAbstractA case of cutaneous leishmaniasis was discovered in a 32-year old man with a persistent erythematous plaque. The patient resides in a high altitude (~2000 m above sea level) area that is not endemic for cutaneous leishmaniasis in the Dunai village of Dolpa, Nepal. The patient's lesion was initially misdiagnosed as...
Source: Parasitology International - September 12, 2019 Category: Parasitology Source Type: research

Alcohol consumption pattern in western Nepal: findings from the COBIN baseline survey
Harmful use of alcohol is a global public health problem. Differences in alcohol consumption patterns may add valuable information to the design of public health interventions to prevent excessive use of alcoh... (Source: BMC Psychiatry)
Source: BMC Psychiatry - September 12, 2019 Category: Psychiatry Authors: Tara Ballav Adhikari, Anupa Rijal, Per Kallestrup and Dinesh Neupane Tags: Research article Source Type: research

Changing epidemiology and antimicrobial resistance in Vibrio cholerae: AMR surveillance findings (2006 –2016) from Nepal
In Nepal, cases of Cholera occur annually either as sporadic or as outbreaks claiming the lives of many in rural areas. The present study is a laboratory based surveillance which aims to analyze the changing e... (Source: BMC Infectious Diseases)
Source: BMC Infectious Diseases - September 11, 2019 Category: Infectious Diseases Authors: Nisha Rijal, Jyoti Acharya, Shailaja Adhikari, Bishnu Psd Upadhaya, Geeta Shakya, Palpasa Kansakar and Piyush Rajbhandari Tags: Research article Source Type: research