Maternal Influenza Immunization and Prevention of Severe Clinical Pneumonia in Young Infants: Analysis of Randomized Controlled Trials Conducted in Nepal, Mali and South Africa
Conclusions: Maternal influenza immunization may reduce severe pneumonia episodes among infants—particularly those too young to be completely vaccinated against Streptococcus pneumoniae and influenza. (Source: The Pediatric Infectious Disease Journal)
Source: The Pediatric Infectious Disease Journal - April 20, 2018 Category: Infectious Diseases Tags: Original Studies Source Type: research

Effectiveness of lockouts in reducing alcohol ‐related harm: Systematic review
Drug and Alcohol Review, EarlyView. (Source: Drug and Alcohol Review)
Source: Drug and Alcohol Review - April 19, 2018 Category: Addiction Authors: Smriti Nepal , Kypros Kypri , Kirrilly Pursey , John Attia , Tanya Chikritzhs , Peter Miller Source Type: research

More major earthquakes at the Nepal Himalaya? – Study on Coulomb stress perspective
Publication date: Available online 17 April 2018 Source:Physics of the Earth and Planetary Interiors Author(s): S.K. Som, Subhrasuchi Sarkar, Soumitra Dasgupta On April, 2015 a major earthquake of 7.9 Mw occurred in the Nepal Himalaya, followed by 553 earthquakes of local magnitude greater than 4.0 within the first 43 days including another major event of 7.3 Mw. We resolve the static coulomb failure stress (CFS) change onto the finite fault models of 7.9 Mw after Elliott et al (2016) and Galezka et al (2015) and its effect on associated receiver faults. Correlation of aftershocks with the enhanced CFS condition shows tha...
Source: Physics of the Earth and Planetary Interiors - April 18, 2018 Category: Physics Source Type: research

Awareness of occupational hazards and associated factors among automobile repair artisans in Kathmandu Metropolitan City, Nepal
Conclusions: Awareness on occupational hazard and use of PPE is very low among automobile repair artisans in Kathmandu, Nepal. Therefore, interventions on awareness raising on areas, like provision of pre-service training, promotion of safety advocacy, and enforcement of appropriate regulations for work place. (Source: Indian Journal of Occupational and Environmental Medicine)
Source: Indian Journal of Occupational and Environmental Medicine - April 18, 2018 Category: Occupational Health Authors: Sujan B Marahatta Sanju Gautam Grish Paudel Uday N Yadav Source Type: research

Integrated genomic and metabolomic profiling of ISC1, an emerging Leishmania donovani population in the Indian subcontinent.
In this study, we perform for the first time an integrated, untargeted genomics and metabolomics approach to characterize ISC1, in comparison with the Core Group (CG), main population that drove the last outbreak of VL in the ISC. We show that the ISC1 population is very different from the CG, both at genome and metabolome levels. These differences included SNPs, CNV and small indels in genes coding for known virulence factors, immunogens and surface proteins. Both genomic and metabolic approaches highlighted dissimilarities related to membrane lipids, the nucleotide salvage pathway and the urea cycle in ISC1 versus CG. Ma...
Source: Infection, Genetics and Evolution - April 18, 2018 Category: Genetics & Stem Cells Authors: Cuypers B, Berg M, Imamura H, Dumetz F, De Muylder G, Domagalska MA, Rijal S, Bhattarai NR, Maes I, Sanders M, Cotton JA, Meysman P, Laukens K, Dujardin JC Tags: Infect Genet Evol Source Type: research

Botany, ethnomedicines, phytochemistry and pharmacology of Himalayan paeony (Paeonia emodi Royle.)
Conclusion P. emodi is endemic to Himalayan region (Pakistan, China, India and Nepal) with diverse traditional therapeutic uses. Majority of reviewed studies showed confusion in its taxonomic validity, incomplete methodologies and ambiguous findings. Keeping in view the immense uses of P. emodi in various traditional medicinal systems, holistic pharmacological approaches in combination with reverse pharmacology, system biology, and “omics” technologies are recommended to improve the quality of research which leads to natural drug discovery development at global perspectives. Graphical abstract (Source: Journal ...
Source: Journal of Ethnopharmacology - April 17, 2018 Category: Drugs & Pharmacology Source Type: research

Identifying the factors associated with depressive symptoms among postpartum mothers in Kathmandu, Nepal
Conclusions This study aids to draw attention on the incorporation of routine screening for basic support and intervention for identified risk factors in postpartum period. Policies can be formulated to encourage postpartum women to obtain adequate rest during pregnancy, support women with poor partner relationship, reduce marital dissatisfaction, help women adjust with stressful life events, and prevent and manage abortion appropriately. These policies may reduce harmful consequences of postpartum depressive symptoms for women, newborn and their family. (Source: International Journal of Nursing Sciences)
Source: International Journal of Nursing Sciences - April 17, 2018 Category: Nursing Source Type: research

Providing palliative care in rural Nepal: Perceptions of mid-level health workers
Conclusion: MHWs practicing in rural areas reported the suffering of patients inflicted with life-limiting illness and their family due to poverty, poor access, lack of resources, social discrimination, and lack of knowledge and skills of the health workers. While there are clear frustrations with the limited resources, there is a willingness to learn among the health workers and provide care in the community. (Source: Indian Journal of Palliative Care)
Source: Indian Journal of Palliative Care - April 13, 2018 Category: Palliative Care Authors: Rajesh N Gongal Shambhu Kumar Upadhyay Kedar Prasad Baral Max Watson George W Kernohan Source Type: research

HPV Screening and Vaccination Strategies in an Unscreened Population: A Mathematical Modeling Study.
This study uses mathematical modeling to explore various vaccination and treatment strategies to control for HPV and cervical cancer while using Nepal as a case study. Two sets of deterministic models were created with the goal of understanding the impact of various prevention and control strategies. The first set of models examines the relative importance of screening and vaccination in an unscreened population, while the second set examines various screening scenarios. Partial rank correlation coefficients confirm the importance of screening and treatment in the reduction of HPV infections and cancer cases even when vacc...
Source: Bulletin of Mathematical Biology - April 12, 2018 Category: Bioinformatics Authors: Milwid RM, Frascoli F, Steben M, Heffernan JM Tags: Bull Math Biol Source Type: research

Social health insurance in Nepal: A health system departure toward the universal health coverage
The International Journal of Health Planning and Management, EarlyView. (Source: The International Journal of Health Planning and Management)
Source: The International Journal of Health Planning and Management - April 10, 2018 Category: Health Management Authors: RajaniPokharel , Pushkar RajSilwal Source Type: research

Perceptions, careseeking, and experiences pertaining to non-cephalic births in rural Sarlahi District, Nepal: a qualitative study
In low-resource settings, a significant proportion of fetal, neonatal, and maternal deaths can be attributed to intrapartum-related complications. Certain risk factors, such as non-cephalic presentation, have ... (Source: BMC Pregnancy and Childbirth)
Source: BMC Pregnancy and Childbirth - April 10, 2018 Category: OBGYN Authors: Naoko Kozuki, Luke C. Mullany, Subarna K. Khatry, James M. Tielsch, Steven C. LeClerq, Caitlin E. Kennedy and Joanne Katz Tags: Research article Source Type: research

Expression and role of PAICS, a de novo purine biosynthetic gene in prostate cancer
The Prostate, EarlyView. (Source: The Prostate)
Source: The Prostate - April 10, 2018 Category: Urology & Nephrology Authors: Balabhadrapatruni V. S. K. Chakravarthi , Moloy T. Goswami , Satya S. Pathi , Matthew Dodson , Darshan S. Chandrashekar , Sumit Agarwal , Saroj Nepal , Sai Akshaya Hodigere Balasubramanya , Javed Siddiqui , Robert J. Lonigro , Arul M. Source Type: research

Qualitative evaluation of mental health training of auxiliary nurse midwives in rural Nepal
Mental illness is increasingly recognized as a global health problem. However, in many countries, including Nepal, it is difficult to talk about mental health problems due to the stigma associated with it. Hence a training programme was developed to train auxiliary nurse midwives, who otherwise are not trained in mental health as part of their pre-registration training in rural Nepal, on issues related to maternal mental health. After training programme a selection of auxiliary nurse midwives were interviewed to establish their views on the training, its usefulness and ways to improve it. (Source: Nurse Education Today)
Source: Nurse Education Today - April 2, 2018 Category: Nursing Authors: Preeti Mahato, Edwin van Teijlingen, Padam Simkhada, Catherine Angell, Jillian Ireland, THET team Source Type: research

Geographical heterogeneity and inequality of access to improved drinking water supply and sanitation in Nepal
Per United Nations ’ Sustainable Development Goals, Nepal is aspiring to achieve universal and equitable access to safe and affordable drinking water and provide access to adequate and equitable sanitation for ... (Source: International Journal for Equity in Health)
Source: International Journal for Equity in Health - April 2, 2018 Category: International Medicine & Public Health Authors: Wen-Jun He, Ying-Si Lai, Biraj M. Karmacharya, Bo-Feng Dai, Yuan-Tao Hao and Dong Roman Xu Tags: Research Source Type: research

Qualitative evaluation of mental health training of auxiliary nurse midwives in rural Nepal
Mental illness is increasingly recognized as a global health problem. However, in many countries, including Nepal, it is difficult to talk about mental health problems due to the stigma associated with it. Hence a training programme was developed to train auxiliary nurse midwives, who otherwise are not trained in mental health as part of their pre-registration training in rural Nepal, on issues related to maternal mental health. After the training programme a selection of auxiliary nurse midwives were interviewed to establish their views on the training, its usefulness and ways to improve it. (Source: Nurse Education Today)
Source: Nurse Education Today - April 2, 2018 Category: Nursing Authors: Preeti K Mahato, Edwin van Teijlingen, Padam Simkhada, Catherine Angell, Jillian Ireland, THET team Source Type: research

S206. knowledge about causes of relapse during psychoeducation in patients living with schizophrenia- a qualitative analysis
Conclusion: Educating our patients can be tiring and mundane during regular out-patient department. However, the psychoeducation sessions are very important part of the treatment. During that process we should anticipate the possible causes of relapse and educate the same for better outcome. (Source: Schizophrenia Bulletin)
Source: Schizophrenia Bulletin - April 1, 2018 Category: Psychiatry Source Type: research

Post-earthquake health-service support, Nepal.
Abstract Problem: Seven months after the April 2015 Nepal earthquake, and as relief efforts were scaling down, health authorities faced ongoing challenges in health-service provision and disease surveillance reporting. Approach: In January 2016, the World Health Organization recruited and trained 12 Nepalese medical doctors to provide technical assistance to the health authorities in the most affected districts by the earthquake. These emergency support officers monitored the recovery of health services and reconstruction of health facilities, monitored stocks of essential medicines, facilitated disease surve...
Source: Bulletin of the World Health Organization - April 1, 2018 Category: International Medicine & Public Health Authors: Goyet S, Rayamajhi R, Gyawali BN, Shrestha BR, Lohani GR, Adhikari D, Salvador E, Ofrin R, Vandelaer J, Samuel R Tags: Bull World Health Organ Source Type: research

Effectiveness of a Mass Media Campaign on Oral Carcinogens and Their Effects on the Oral Cavity
Conclusions: The mass media campaign was an effective tool for increasing awareness among the population. PMID: 29582640 [PubMed - in process] (Source: Asian Pacific Journal of Cancer Prevention)
Source: Asian Pacific Journal of Cancer Prevention - March 29, 2018 Category: Cancer & Oncology Tags: Asian Pac J Cancer Prev Source Type: research

An integrated community health worker intervention in rural Nepal: a type 2 hybrid effectiveness-implementation study protocol
Evidence-based medicines, technologies, and protocols exist to prevent many of the annual 300,000 maternal, 2.7 million neonatal, and 9 million child deaths, but they are not being effectively implemented and ... (Source: Implementation Science)
Source: Implementation Science - March 29, 2018 Category: Health Management Authors: Sheela Maru, Isha Nirola, Aradhana Thapa, Poshan Thapa, Lal Kunwar, Wan-Ju Wu, Scott Halliday, David Citrin, Ryan Schwarz, Indira Basnett, Naresh KC, Khem Karki, Pushpa Chaudhari and Duncan Maru Tags: Study protocol Source Type: research

Television advertising of food during children's programming in Nepal
• In Nepal, 57 hours of children's television programming were recorded.• 1,203 food commercials were analyzed for nutrient content and marketing appeals.• 70% of commercials advertised foods had high saturated fat, sugar, and/or sodium.• Every commercial featured a children-directed appeal (e.g., animated effects). (Source: Nutrition)
Source: Nutrition - March 29, 2018 Category: Nutrition Authors: Andrew D. Menger-Ogle, Ashlie Johnson, John A. Morgan, Dan J. Graham Tags: Brief Report Source Type: research

Plasma proteins associated with circulating carotenoids in Nepalese school-aged children.
Abstract Carotenoids are naturally occurring pigments that function as vitamin A precursors, antioxidants, anti-inflammatory agents or biomarkers of recent vegetable and fruit intake, and are thus important for population health and nutritional assessment. An assay approach that measures proteins could be more technologically feasible than chromatography, thus enabling more frequent carotenoid status assessment. We explored associations between proteomic biomarkers and concentrations of 6 common dietary carotenoids (α-carotene, β-carotene, lutein/zeaxanthin, β-cryptoxanthin, and lycopene) in plasma...
Source: Archives of Biochemistry and Biophysics - March 29, 2018 Category: Biochemistry Authors: Eroglu A, Schulze KJ, Yager J, Cole RN, Christian P, Nonyane BAS, Lee SE, Fune Wu LS, Khatry S, Groopman J, West KP Tags: Arch Biochem Biophys Source Type: research

Television advertising of food during children's programming in Nepal
• In Nepal, 57 hours of children's television programming were recorded.• 1,203 food commercials were analyzed for nutrient content and marketing appeals.• 70% of commercials advertised foods had high saturated fat, sugar, and/or sodium.• Every commercial featured a children-directed appeal (e.g., animated effects). (Source: Nutrition)
Source: Nutrition - March 29, 2018 Category: Nutrition Authors: Andrew D. Menger-Ogle, Ashlie Johnson, John A. Morgan, Dan J. Graham Tags: Brief Report Source Type: research

Antibiotic resistance pattern and virulence genes content in avian pathogenic Escherichia coli (APEC) from broiler chickens in Chitwan, Nepal
Avian pathogenic Escherichia coli (APEC) are causative agent of extraintestinal infections, collectively known as colibacillosis, which results significant losses in poultry industries. The extraintestinal surviv... (Source: BMC Veterinary Research)
Source: BMC Veterinary Research - March 27, 2018 Category: Veterinary Research Authors: Manita Subedi, Himal Luitel, Bhuminanda Devkota, Rebanta Kumar Bhattarai, Sarita Phuyal, Prabhat Panthi, Anil Shrestha and Dhiraj Kumar Chaudhary Tags: Research article Source Type: research

New forms of development: branding innovative ideas and bidding for foreign aid in the maternal and child health service in Nepal
Nepal has been receiving foreign aid since the early 1950s. Currently, the country ’s health care system is heavily dependent on aid, even for the provision of basic health services to its people. Globally, the... (Source: Globalization and Health)
Source: Globalization and Health - March 27, 2018 Category: International Medicine & Public Health Authors: Radha Adhikari, Pam Smith, Jeevan Raj Sharma and Obindra Bahadur Chand Tags: Research Source Type: research

Regional Gastrointestinal Absorption of Apixaban in Healthy Subjects.
This study was conducted to investigate the extent of absorption in different regions of the gastrointestinal (GI) tract. The relative bioavailability of an apixaban crushed tablet was also assessed to investigate the effect of dissolution on absorption. This was an open-label, randomized, 4-period, 4-treatment crossover study with a 7-day washout period balanced for first-order residual effects in 12 healthy subjects. Subjects received a single dose of a 2.5-mg apixaban solution administered orally, released in the distal small intestine and in the ascending colon. In addition, subjects received a single dose of a 2.5-mg ...
Source: The Journal of Clinical Pharmacology - March 26, 2018 Category: Drugs & Pharmacology Authors: Byon W, Nepal S, Schuster AE, Shenker A, Frost CE Tags: J Clin Pharmacol Source Type: research

Nutrition ‐sensitive agricultural interventions and gender dynamics: A qualitative study in Nepal
Maternal&Child Nutrition, EarlyView. (Source: Maternal and Child Nutrition)
Source: Maternal and Child Nutrition - March 24, 2018 Category: Nutrition Source Type: research

Feasibility study of a family- and school-based intervention for child behavior problems in Nepal
This study evaluates the feasibility, acceptability, and outcomes of a combined school- and family-based intervention, delivered by psychosocial counselors, for children with behavior problems in rural Nepal. (Source: Child and Adolescent Psychiatry and Mental Health)
Source: Child and Adolescent Psychiatry and Mental Health - March 23, 2018 Category: Psychiatry Authors: Ramesh P. Adhikari, Nawaraj Upadhaya, Emily N. Satinsky, Matthew D. Burkey, Brandon A. Kohrt and Mark J. D. Jordans Tags: Research article Source Type: research

"They Will Come to Understand": Supervisor Reflections on International Medical Electives.
"They Will Come to Understand": Supervisor Reflections on International Medical Electives. Teach Learn Med. 2018 Mar 22;:1-9 Authors: Roebbelen E, Dorman K, Hunter A, Kraeker C, O'Shea T, Bozinoff N Abstract Phenomenon: Increasing numbers of medical students from high-income countries are undertaking international medical electives (IMEs) during their training. Much has been written about the benefits of these experiences for the student, and concerns have been raised regarding the burden of IMEs on host communities. The voices of physicians from low- and middle-income countries who supervis...
Source: Teaching and Learning in Medicine - March 22, 2018 Category: Universities & Medical Training Authors: Roebbelen E, Dorman K, Hunter A, Kraeker C, O'Shea T, Bozinoff N Tags: Teach Learn Med Source Type: research

Opportunities, challenges and strategies when building a midwifery profession. Findings from a qualitative study in Bangladesh and Nepal
Conclusion and clinical application This study demonstrated that building a midwifery profession requires a political comprehensive collaborative approach supported by a political commitment. Through bringing professionals together in a professional association will bring a professional status. Global standards and guidelines need to be contextualized into national policies and plans where midwives are included as part of the national health workforce. This is a key for creating recognized midwives with a protected title to autonomously practice midwifery, to upholding the sexual and reproductive health and rights for wome...
Source: Sexual and Reproductive Healthcare - March 20, 2018 Category: Reproduction Medicine Source Type: research

High altitude organic gold: The production network for Ophiocordyceps sinensis from far-western Nepal
Conclusions O. sinensis income is of major economic importance for rural households at the margin of its distribution range in Nepal. Production networks operated by informal actors establishing trust-based relationships allow responses to cross-border market signals, enabling the flow of rural and remote environmental resources to urban centres of demand. There is scope for public interventions, e.g. to determine the drivers of demand. Graphical abstract (Source: Journal of Ethnopharmacology)
Source: Journal of Ethnopharmacology - March 19, 2018 Category: Drugs & Pharmacology Source Type: research

APIM-peptide targeting PCNA improves the efficacy of docetaxel treatment in the TRAMP mouse model of prostate cancer.
Authors: Søgaard CK, Moestue SA, Rye MB, Kim J, Nepal A, Liabakk NB, Bachke S, Bathen TF, Otterlei M, Hill DK Abstract Docetaxel is the chemotherapeutic choice for metastatic hormone-refractory prostate cancer, however, it only marginally improves the survival rate. The purpose of the present study was to examine if a peptide targeting the cellular scaffold protein PCNA could improve docetaxel's efficacy. We found that docetaxel given in combination with a cell penetrating peptide containing the AlkB homolog 2 PCNA interacting motif (APIM-peptide), reduced the prostate volume and limited prostate cancer regr...
Source: Oncotarget - March 18, 2018 Category: Cancer & Oncology Tags: Oncotarget Source Type: research

Seasonal Hyperacute Panuveitis in Nepal: A Review over 40  Years of Surveillance.
CONCLUSIONS: Although SHAPU has been reported only from Nepal, lack of its report from ecologically similar terrain along Hindukush Mountains and possible association with moths remain intriguing. PMID: 29543556 [PubMed - as supplied by publisher] (Source: Ocular Immunology and Inflammation)
Source: Ocular Immunology and Inflammation - March 17, 2018 Category: Allergy & Immunology Tags: Ocul Immunol Inflamm Source Type: research

IJERPH, Vol. 15, Pages 535: Condom Use at Last Sexual Intercourse and Its Correlates among Males and Females Aged 15 –49 Years in Nepal
This study aimed to assess the prevalence and correlates of condom use at last sexual intercourse among people aged 15–49 years in Nepal. Secondary data analysis was performed using the Nepal Demographic and Health Survey 2011. The study was restricted to the respondents who reported ever having had sexual intercourse; 9843 females and 3017 males were included. Condom use was assessed by asking if respondents used condoms in their most recent sexual intercourse. Chi-square test and multivariate logistic regression analysis were performed using Complex Sample Analysis Procedure to adjust for sample weight and multista...
Source: International Journal of Environmental Research and Public Health - March 16, 2018 Category: Environmental Health Authors: Bimala Sharma Eun Nam Tags: Article Source Type: research

Study of abnormalities in protocol graft kidney biopsy done at six months post transplantation in a tertiary care center hospital of Nepal
Increasing the graft survival is the prime focus of every transplantation program. Detection of subclinical abnormalities with the help of protocol renal graft biopsies performed at pre-determined interval after transplantation has been one of the approaches. (Source: Transplantation Proceedings)
Source: Transplantation Proceedings - March 15, 2018 Category: Transplant Surgery Authors: Midhan Shrestha, Dibya Singh, Mahesh Raj Sigdel, Mukunda Prasad Kafle Source Type: research

Observation of optical properties and sources of aerosols at Buddha's birthplace, Lumbini, Nepal: environmental implications.
Abstract For the first time, aerosol optical properties are measured over Lumbini, Nepal, with CIMEL sunphotometer of the Aerosol Robotic Network (AERONET) program. Lumbini is a sacred place as the birthplace of Lord Buddha, and thus a UNESCO world heritage site, located near the northern edge of the central Indo-Gangetic Plains (IGP) and before the Himalayan foothills (and Himalayas) to its north. Average aerosol optical depth (AOD) is found to be 0.64 ± 0.38 (0.06-3.28) over the sampling period (January 2013-December 2014), with the highest seasonal AOD during the post-monsoon season (0.72&t...
Source: Environmental Science and Pollution Research International - March 15, 2018 Category: Environmental Health Authors: Rupakheti D, Kang S, Rupakheti M, Cong Z, Tripathee L, Panday AK, Holben BN Tags: Environ Sci Pollut Res Int Source Type: research

Study of abnormalities in protocol graft kidney biopsy done at six months post transplantation in a tertiary care center hospital of Nepal
Increasing the graft survival is the prime focus of every transplantation program. Detection of subclinical abnormalities with the help of protocol renal graft biopsies performed at pre-determined interval after transplantation has been one of the approaches. (Source: Transplantation Proceedings)
Source: Transplantation Proceedings - March 15, 2018 Category: Transplant Surgery Authors: Midhan Shrestha, Dibya Singh, Mahesh Raj Sigdel, Mukunda Prasad Kafle Source Type: research

GSE111765 RNA seq analysis on zebrafish Notch 3 mutants and adult neural stem cells
Contributors : Emmanuel Than-Trong ; Alessandro Alunni ; S ébastien Mella ; Chirag Nepal ; Sara OrticaSeries Type : Expression profiling by high throughput sequencingOrganism : Danio rerioThe goal of this study is to identify the Notch3 targets directly responsible for maintaining the quiescent state and the stemness of adult pallial zebrafish Radial Glia. (Source: GEO: Gene Expression Omnibus)
Source: GEO: Gene Expression Omnibus - March 14, 2018 Category: Genetics & Stem Cells Tags: Expression profiling by high throughput sequencing Danio rerio Source Type: research

Mitochondrial DNA analyses and ecological niche modeling reveal post ‐LGM expansion of the Assam macaque (Macaca assamensis) in the foothills of Nepal Himalaya
American Journal of Primatology, EarlyView. (Source: American Journal of Primatology)
Source: American Journal of Primatology - March 14, 2018 Category: Psychiatry & Psychology Source Type: research

Post Earthquake Equilibrium Disturbance: A Study After Nepal –India Earthquake 2015
Abstract Nepal and adjoining areas of India suffered a series of massive earthquakes in April –May 2015. This was followed by a remarkable increase in the patient presenting with vague dizziness like features which could not be attributed to any defined variant of vestibular disorder. Extensive search of literature revealed only scarce information about ambiguous post-earthquake vestibular symptoms and their management. We performed a detailed epidemiological analysis of these patients to analyse the presentation, underlying mechanism and optimal management. The results were scrutinised in light of existing interna...
Source: Indian Journal of Otolaryngology and Head and Neck Surgery - March 13, 2018 Category: ENT & OMF Source Type: research

Backpackers in the Nepal 2015 earthquake: The contribution of personal and social resources to mental health
In this study, we focused specifically on backpackers who were in Nepal at the time of the 2015 earthquake, and survived. Our aim was to estimate factors that protect a backpacker's mental health after an earthquake, to deepen social workers’ knowledge regarding potential effective interventions. Based on the conservation of resources theory, we examined the contribution of optimism, emotion regulation, as well as the support of family and friends to backpackers’ mental health. A cross‐sectional sample survey was conducted to collect data from 145 backpackers 1 week to 3 months after the disaster. The fi...
Source: Journal of Community Psychology - March 12, 2018 Category: Psychiatry & Psychology Authors: Shlomit Weiss ‐Dagan, Haya Itzhaky, Orit Taubman‐Ben‐Ari Tags: ARTICLE Source Type: research

Diagnostic use of lung ultrasound compared to chest radiograph for suspected pneumonia in a resource-limited setting
ConclusionsBedside lung ultrasound demonstrated better sensitivity than chest X-ray for the diagnosis of pneumonia in Nepal.Trial registrationClinicalTrials.gov, registration numberNCT02949141. Registered 31 October 2016. (Source: International Journal of Emergency Medicine)
Source: International Journal of Emergency Medicine - March 12, 2018 Category: Emergency Medicine Source Type: research

A simple in chemico method for testing skin sensitizing potential of chemicals using small endogenous molecules.
Abstract Among many of the validated methods for testing skin sensitization, direct peptide reactivity assay (DPRA) employs no cells or animals. Although no immune cells are involved in this assay, it reliably predicts the skin sensitization potential of a chemical in chemico. Herein, a new method was developed using endogenous small-molecular-weight compounds, cysteamine and glutathione, rather than synthetic peptides, to differentiate skin sensitizers from non-sensitizers with an accuracy as high as DPRA. The percent depletion of cysteamine and glutathione by test chemicals was measured by an HPLC equipped with ...
Source: Toxicology Letters - March 12, 2018 Category: Toxicology Authors: Nepal MR, Shakya R, Kang MJ, Jeong TC Tags: Toxicol Lett Source Type: research

Backpackers in the Nepal 2015 earthquake: The contribution of personal and social resources to mental health
Journal of Community Psychology, EarlyView. (Source: Journal of Community Psychology)
Source: Journal of Community Psychology - March 12, 2018 Category: Psychiatry & Psychology Source Type: research

Prevalence of cardiovascular disease risk factors: A community-based cross-sectional study in a peri-urban community of Kathmandu, Nepal
Conclusion A high prevalence of cardiovascular disease risk factors and their disproportional distribution among the study population indicated an inevitable risk of cardiovascular events in near future. (Source: Indian Heart Journal)
Source: Indian Heart Journal - March 10, 2018 Category: Cardiology Source Type: research

IJERPH, Vol. 15, Pages 484: Relationships among Safety Climate, Safety Behavior, and Safety Outcomes for Ethnic Minority Construction Workers
This study aims to investigate relationships among safety climate, safety behavior, and safety outcomes for EM construction workers. To this end, a theoretical research model was developed based on a comprehensive review of the current literature. In total, 289 valid questionnaires were collected face-to-face from 223 Nepalese construction workers and 56 Pakistani construction workers working on 15 construction sites in Hong Kong. Structural equation modelling was employed to validate the constructs and test the hypothesized model. Results show that there were significant positive relationships between safety climate and s...
Source: International Journal of Environmental Research and Public Health - March 9, 2018 Category: Environmental Health Authors: Sainan Lyu Carol K. H. Hon Albert P. C. Chan Francis K. W. Wong Arshad Ali Javed Tags: Article Source Type: research

UBC-Nepal Expedition: Imposed oscillatory shear stress does not further attenuate flow-mediated dilation during acute and sustained hypoxia.
Abstract Experimentally-induced oscillatory shear stress (OSS) and hypoxia reduce endothelial function in humans. Acute and sustained hypoxia may cause increases in resting OSS; however, whether this influences endothelial susceptibility to further increases in OSS is unknown. Healthy lowlanders (n=15, 30{plus minus}6 years [mean{plus minus}SD]) participated in three OSS interventions; two at sea level (normoxia and following 20-minutes of normobaric hypoxia [acute hypoxia, 11% O2]) and one 5-7 days after a 9-day ascent to 5050m (sustained hypoxia). OSS was provoked in the brachial artery using a 30-minute distal ...
Source: American Journal of Physiology. Heart and Circulatory Physiology - March 9, 2018 Category: Physiology Authors: Tremblay JC, Howe CA, Ainslie PN, Pyke KE Tags: Am J Physiol Heart Circ Physiol Source Type: research

Comparison of radiofrequency electromagnetic field exposure levels in different everyday microenvironments in an international context.
CONCLUSIONS: This study demonstrates high RF-EMF variability between the 94 selected microenvironments from all over the world. Exposure levels tended to increase with increasing urbanity. In most microenvironments downlink from mobile phone base stations is the most relevant contributor. PMID: 29529581 [PubMed - as supplied by publisher] (Source: Environment International)
Source: Environment International - March 9, 2018 Category: Environmental Health Authors: Sagar S, Adem SM, Struchen B, Loughran SP, Brunjes ME, Arangua L, Dalvie MA, Croft RJ, Jerrett M, Moskowitz JM, Kuo T, Röösli M Tags: Environ Int Source Type: research

UBC ‐Nepal expedition: The use of oral antioxidants does not alter cerebrovascular function at sea level or high altitude
Experimental Physiology, EarlyView. (Source: Experimental Physiology)
Source: Experimental Physiology - March 8, 2018 Category: Physiology Source Type: research

UBC ‐Nepal expedition: The use of oral antioxidants does not alter cerebrovascular function at sea level or high altitude
Experimental Physiology,Volume 103, Issue 4, Page 523-534, 1 April 2018. (Source: Experimental Physiology)
Source: Experimental Physiology - March 8, 2018 Category: Physiology Authors: Alexander B.Hansen , Ryan L.Hoiland , Nia C. S.Lewis , Michael M.Tymko , Joshua C.Tremblay , MichaelStembridge , DanielaNowak ‐Flück , Howard H.Carter , Damian M.Bailey , Philip N.Ainslie Source Type: research