Hereditary spherocytosis in a young female in Eastern Nepal: a case report
CONCLUSION: HS remains underdiagnosed, especially in our regions. The osmotic fragility test emerges as an economical diagnostic tool in resource-limited settings, particularly when spherocytosis is absent in the peripheral blood smears. Its inclusion in diagnostic protocols can expedite accurate HS identification and enhance patient outcomes.PMID:38463107 | PMC:PMC10923321 | DOI:10.1097/MS9.0000000000001804 (Source: Annals of Medicine)
Source: Annals of Medicine - March 11, 2024 Category: Internal Medicine Authors: Anusha Rayamajhi Manisha Shrestha Priyanka K C Robin Maskey Source Type: research

Point prevalence and clinical profile of patients with delirium admitted in internal medicine department at tertiary care centre in eastern Nepal: a descriptive cross-sectional study
CONCLUSIONS: This study provides critical insights into delirium prevalence and profiles in Eastern Nepal. Identified risk factors underscore the importance of routine screenings and targeted interventions for at-risk populations. Study limitations, including sample size and single-centre focus, call for further research to validate findings and enhance our understanding of delirium's management across diverse healthcare settings. Overall, the study informs clinical practices and prompts broader exploration of delirium in healthcare contexts.PMID:38463110 | PMC:PMC10923295 | DOI:10.1097/MS9.0000000000001761 (Source: Annals of Medicine)
Source: Annals of Medicine - March 11, 2024 Category: Internal Medicine Authors: Tek Nath Yogi Sujan Puri Bhupendra Shah Suraj Nepal Akshat Mishra Source Type: research

Evaluation of variations of optic nerve course in relation to posterior paranasal sinuses in MDCT in a tertiary care center of Nepal: a retrospective cross-section study
CONCLUSION: An understanding of the relationship between optic nerves and posterior PNS, as well as awareness of optic nerve dehiscence, is essential in preventing injuries during sinus surgeries. Type 1 optic nerve predominates among Nepalese patients visiting our hospital.PMID:38463119 | PMC:PMC10923376 | DOI:10.1097/MS9.0000000000001697 (Source: Annals of Medicine)
Source: Annals of Medicine - March 11, 2024 Category: Internal Medicine Authors: Prajwal Dahal Sabina Parajuli Prajina Pradhan Santosh Maharjan Govinda Adhikari Ongden Y Tamang Rudra P Upadhyaya Kapil Dawadi Ashish Shrestha Source Type: research

Microsurgical treatment of posterior circulation aneurysms: an institutional experience from Nepal
CONCLUSIONS: The patient characteristics and outcome are comparable with those described in the literature from other countries. With an individualized and careful selection strategy, our results are satisfactory despite fewer operations.PMID:38463098 | PMC:PMC10923320 | DOI:10.1097/MS9.0000000000001785 (Source: Annals of Medicine)
Source: Annals of Medicine - March 11, 2024 Category: Internal Medicine Authors: Mohan Raj Sharma Susmin Karki Amit B Pradhanang Gopal Sedain Source Type: research

Hereditary spherocytosis in a young female in Eastern Nepal: a case report
CONCLUSION: HS remains underdiagnosed, especially in our regions. The osmotic fragility test emerges as an economical diagnostic tool in resource-limited settings, particularly when spherocytosis is absent in the peripheral blood smears. Its inclusion in diagnostic protocols can expedite accurate HS identification and enhance patient outcomes.PMID:38463107 | PMC:PMC10923321 | DOI:10.1097/MS9.0000000000001804 (Source: Annals of Medicine)
Source: Annals of Medicine - March 11, 2024 Category: Internal Medicine Authors: Anusha Rayamajhi Manisha Shrestha Priyanka K C Robin Maskey Source Type: research

Point prevalence and clinical profile of patients with delirium admitted in internal medicine department at tertiary care centre in eastern Nepal: a descriptive cross-sectional study
CONCLUSIONS: This study provides critical insights into delirium prevalence and profiles in Eastern Nepal. Identified risk factors underscore the importance of routine screenings and targeted interventions for at-risk populations. Study limitations, including sample size and single-centre focus, call for further research to validate findings and enhance our understanding of delirium's management across diverse healthcare settings. Overall, the study informs clinical practices and prompts broader exploration of delirium in healthcare contexts.PMID:38463110 | PMC:PMC10923295 | DOI:10.1097/MS9.0000000000001761 (Source: Annals of Medicine)
Source: Annals of Medicine - March 11, 2024 Category: Internal Medicine Authors: Tek Nath Yogi Sujan Puri Bhupendra Shah Suraj Nepal Akshat Mishra Source Type: research

Evaluation of variations of optic nerve course in relation to posterior paranasal sinuses in MDCT in a tertiary care center of Nepal: a retrospective cross-section study
CONCLUSION: An understanding of the relationship between optic nerves and posterior PNS, as well as awareness of optic nerve dehiscence, is essential in preventing injuries during sinus surgeries. Type 1 optic nerve predominates among Nepalese patients visiting our hospital.PMID:38463119 | PMC:PMC10923376 | DOI:10.1097/MS9.0000000000001697 (Source: Annals of Medicine)
Source: Annals of Medicine - March 11, 2024 Category: Internal Medicine Authors: Prajwal Dahal Sabina Parajuli Prajina Pradhan Santosh Maharjan Govinda Adhikari Ongden Y Tamang Rudra P Upadhyaya Kapil Dawadi Ashish Shrestha Source Type: research

Appropriate complementary feeding practice and associated factors among mothers of children aged 6 –23 months in Bhimphedi rural municipality of Nepal
ConclusionThis study revealed that a significant proportion of mothers had inappropriate complementary feeding practice for their children aged 6 –23 months. This study highlights the need for behavior change communication and promotion of kitchen garden to address the associated factors and promote appropriate complementary feeding practice. (Source: PLoS One)
Source: PLoS One - March 6, 2024 Category: Biomedical Science Authors: Thag Bahadur Gurung Source Type: research

Addressing the Critical Gap: Ensuring Urgent Access to Palliative Care Services with Essential Medications in Nepal
This article discusses the existing efforts and noteworthy initiatives implemented by healthcare institutions. However, these efforts are currently limited in scale. We recommend including essential palliative care medicines in government healthcare policies, establishing training programs for healthcare professionals, and developing comprehensive policies with detailed field research work to meet the growing demand. Addressing these issues will significantly improve the quality of life for palliative care patients in Nepal.PMID:38441942 | DOI:10.1080/15360288.2024.2320384 (Source: Journal of Pain and Palliative Care Pharmacotherapy)
Source: Journal of Pain and Palliative Care Pharmacotherapy - March 5, 2024 Category: Palliative Care Authors: Rajeev Shrestha Sunil Shrestha Source Type: research

Understanding of disease status, prognosis and estimated cost of treatment among cancer patients: experience from a tertiary cancer centre in Nepal
CONCLUSION: The level of understanding is low for most patients and their immediate caregivers, particularly among those who are female, not literate and whose primary language is not Nepali. Appropriate strategy should be adopted to enhance basic understanding among patients and caregivers in our setting.PMID:38439816 | PMC:PMC10911673 | DOI:10.3332/ecancer.2024.1668 (Source: Ecancermedicalscience)
Source: Ecancermedicalscience - March 5, 2024 Category: Cancer & Oncology Authors: Shweta Baral Sudhir Raj Silwal Deep Lamichhane Abish Adhikari Nancy Bhattarai Source Type: research

The differential needs and expectations from general practitioners in oncology between high-income countries and low- and-middle-income countries: results from a survey of Canadian and Nepali oncologists
CONCLUSION: We found many similarities in oncologist's opinions of GPOs between the two countries, however, there were also some notable differences such as the need to provide cancer screening services in Nepal. This highlights the need to tailor GPO training programs based on local context.PMID:38439813 | PMC:PMC10911672 | DOI:10.3332/ecancer.2024.1673 (Source: Ecancermedicalscience)
Source: Ecancermedicalscience - March 5, 2024 Category: Cancer & Oncology Authors: Bishal Gyawali Bishesh Sharma Poudyal Laura M Carson Colleen Savage Ramila Shilpakar Scott Berry Source Type: research

Multiple pathogen contamination of water, hands, and fomites in rural Nepal and the effect of WaSH interventions
This study provides an understanding of WaSH intervention on microbe concentrations. Such data could help with better planning of intervention activities in the future.PMID:38442666 | DOI:10.1016/j.ijheh.2024.114341 (Source: International Journal of Hygiene and Environmental health)
Source: International Journal of Hygiene and Environmental health - March 5, 2024 Category: Environmental Health Authors: Sital Uprety Isaac Ngo Marika Maggos Bipin Dangol Samendra P Sherchan Joanna L Shisler Mohan Amarasiri Daisuke Sano Thanh H Nguyen Source Type: research

Addressing the Critical Gap: Ensuring Urgent Access to Palliative Care Services with Essential Medications in Nepal
This article discusses the existing efforts and noteworthy initiatives implemented by healthcare institutions. However, these efforts are currently limited in scale. We recommend including essential palliative care medicines in government healthcare policies, establishing training programs for healthcare professionals, and developing comprehensive policies with detailed field research work to meet the growing demand. Addressing these issues will significantly improve the quality of life for palliative care patients in Nepal.PMID:38441942 | DOI:10.1080/15360288.2024.2320384 (Source: Journal of Pain and Palliative Care Pharmacotherapy)
Source: Journal of Pain and Palliative Care Pharmacotherapy - March 5, 2024 Category: Palliative Care Authors: Rajeev Shrestha Sunil Shrestha Source Type: research

Understanding of disease status, prognosis and estimated cost of treatment among cancer patients: experience from a tertiary cancer centre in Nepal
CONCLUSION: The level of understanding is low for most patients and their immediate caregivers, particularly among those who are female, not literate and whose primary language is not Nepali. Appropriate strategy should be adopted to enhance basic understanding among patients and caregivers in our setting.PMID:38439816 | PMC:PMC10911673 | DOI:10.3332/ecancer.2024.1668 (Source: Ecancermedicalscience)
Source: Ecancermedicalscience - March 5, 2024 Category: Cancer & Oncology Authors: Shweta Baral Sudhir Raj Silwal Deep Lamichhane Abish Adhikari Nancy Bhattarai Source Type: research

The differential needs and expectations from general practitioners in oncology between high-income countries and low- and-middle-income countries: results from a survey of Canadian and Nepali oncologists
CONCLUSION: We found many similarities in oncologist's opinions of GPOs between the two countries, however, there were also some notable differences such as the need to provide cancer screening services in Nepal. This highlights the need to tailor GPO training programs based on local context.PMID:38439813 | PMC:PMC10911672 | DOI:10.3332/ecancer.2024.1673 (Source: Ecancermedicalscience)
Source: Ecancermedicalscience - March 5, 2024 Category: Cancer & Oncology Authors: Bishal Gyawali Bishesh Sharma Poudyal Laura M Carson Colleen Savage Ramila Shilpakar Scott Berry Source Type: research