Exploring neonicotinoid effects on Drosophila: insights into olfactory memory, neurotransmission, and synaptic connectivity
This study focuses on the fruit fly Drosophila melanogaster, chosen for its genetic tractability, well-characterized neural circuitry, and remarkable parallels with bees in neurotransmitter systems and brain structures. Our aim is to establish the fruit fly as a valuable model organism for studying the effects of neonicotinoids on behavior and neuronal circuitry, with particular attention to olfactory memory and associated brain circuitries. To achieve this aim, we conducted experiments to investigate the effects of short-term exposure to sublethal doses of the neonicotinoid imidacloprid, mimicking realistic environmental ...
Source: Frontiers in Physiology - March 14, 2024 Category: Physiology Source Type: research
Construction of cellulose-degrading microbial consortium and evaluation of their ability to degrade spent mushroom substrate
In this study, four strains of cellulose-degrading bacteria were screened, and F16, F, and F7 were identified as B. amyloliquefaciens, PX1 identified as B. velezensis. At the same time, two groups of cellulose efficient degrading microbial consortiums (PX1 + F7 and F16 + F) were successfully constructed. When SMS was used as the sole carbon source, their carboxymethyl cellulase (CMCase) activities were 225.16 and 156.63 U/mL, respectively, and the filter paper enzyme (FPase) activities were 1.91 and 1.64 U/mL, respectively. PX1 + F7 had the highest degradation rate of hemicellulose and lignin, reaching 52.96% and 52.13%, r...
Source: Frontiers in Microbiology - March 14, 2024 Category: Microbiology Source Type: research
Comprehensive review on recent trends and perspectives of natural exo-polysaccharides: Pioneering nano-biotechnological tools
This article shifts away from the conventional utility to delve deeply into the expansive landscape of EPS applications, particularly highlighting their integration into cutting-edge nanobiotechnological methods. Exploring EPS synthesis, extraction, composition, and properties, the discussion emphasizes their structural diversity with molecular weight and heteropolymer compositions. Their role as raw materials for value-added products takes center stage, with critical insights into recent applications in nanobiotechnology. The multifaceted potential, biological relevance, and commercial applicability of EPSs in contemporar...
Source: International Journal of Biological Macromolecules - March 13, 2024 Category: Biochemistry Authors: Onkar Nath Tiwari Md Nazneen Bobby Vanitha Kondi Gopinath Halder Hanieh Kargarzadeh Abu Md Ashif Ikbal Biswanath Bhunia Sabu Thomas Thomas Efferth Debprasad Chattopadhyay Partha Palit Source Type: research
Comprehensive review on recent trends and perspectives of natural exo-polysaccharides: Pioneering nano-biotechnological tools
This article shifts away from the conventional utility to delve deeply into the expansive landscape of EPS applications, particularly highlighting their integration into cutting-edge nanobiotechnological methods. Exploring EPS synthesis, extraction, composition, and properties, the discussion emphasizes their structural diversity with molecular weight and heteropolymer compositions. Their role as raw materials for value-added products takes center stage, with critical insights into recent applications in nanobiotechnology. The multifaceted potential, biological relevance, and commercial applicability of EPSs in contemporar...
Source: International Journal of Biological Macromolecules - March 13, 2024 Category: Biochemistry Authors: Onkar Nath Tiwari Md Nazneen Bobby Vanitha Kondi Gopinath Halder Hanieh Kargarzadeh Abu Md Ashif Ikbal Biswanath Bhunia Sabu Thomas Thomas Efferth Debprasad Chattopadhyay Partha Palit Source Type: research
Exploring the Anti-Cancer Potential of Hispidin: A Comprehensive In Silico and In Vitro Study on Human Osteosarcoma Saos2 Cells
Chem Biodivers. 2024 Mar 8:e202301833. doi: 10.1002/cbdv.202301833. Online ahead of print.ABSTRACTHispidin was initially discovered in basidiomycete Inonotus hispidus (Bull.) P. Karst and this extraordinary compound possesses immense potency and can be extracted from the wild mushroom through specialized bioreactor cultivation techniques. In our study, we isolated it from Inonotus hispidus (Bull.) P. Karst., with a yield of 3.6%. We identified and characterized hispidin through the implementation of spectroscopic techniques such as FTIR, NMR, and MS. Additionally, we utilized Thermogravimetric Analysis for thermal characte...
Source: Chemistry and Biodiversity - March 8, 2024 Category: Biochemistry Authors: Khedidja Benarous Arif Mermer Talia Serseg Aydin Tahmasebifar Houssem Boulebd Abderahmane Linani Source Type: research
Lentinan-loaded GelMA hydrogel accelerates diabetic wound healing through enhanced angiogenesis and immune microenvironment modulation
Int J Biol Macromol. 2024 Mar 6:130716. doi: 10.1016/j.ijbiomac.2024.130716. Online ahead of print.ABSTRACTDiabetic wound healing is a substantial clinical challenge, characterized by delayed angiogenesis and unresolved inflammation. Lentinan, a polysaccharide extracted from shiitake mushrooms, has the potential to regulate both macrophage polarization and angiogenesis, though this aspect remains inadequately explored. To facilitate lentinan's clinical utility, we have developed a GelMA hydrogel encapsulated with lentinan (10 μM), offering a controlled release mechanism for sustained lentinan delivery at the wound site. A...
Source: International Journal of Biological Macromolecules - March 8, 2024 Category: Biochemistry Authors: Zhiwei Jia Lei Chen Dongqiang Gu Xingxuan Li Tianlin Wen Wei Li Source Type: research
Exploring the Anti-Cancer Potential of Hispidin: A Comprehensive In Silico and In Vitro Study on Human Osteosarcoma Saos2 Cells
Chem Biodivers. 2024 Mar 8:e202301833. doi: 10.1002/cbdv.202301833. Online ahead of print.ABSTRACTHispidin was initially discovered in basidiomycete Inonotus hispidus (Bull.) P. Karst and this extraordinary compound possesses immense potency and can be extracted from the wild mushroom through specialized bioreactor cultivation techniques. In our study, we isolated it from Inonotus hispidus (Bull.) P. Karst., with a yield of 3.6%. We identified and characterized hispidin through the implementation of spectroscopic techniques such as FTIR, NMR, and MS. Additionally, we utilized Thermogravimetric Analysis for thermal characte...
Source: Chemistry and Biodiversity - March 8, 2024 Category: Biochemistry Authors: Khedidja Benarous Arif Mermer Talia Serseg Aydin Tahmasebifar Houssem Boulebd Abderahmane Linani Source Type: research
Extraction, structure and antioxidant activity of the polysaccharides from morels (Morchella spp.): A review
Int J Biol Macromol. 2024 Mar 5:130656. doi: 10.1016/j.ijbiomac.2024.130656. Online ahead of print.ABSTRACTMorels (Morchella spp.), which are cultivated only in a few regions of the world, are edible mushrooms known for their various properties including antioxidation, immune regulation, antiinflammation, and antitumor effects. Polysaccharides from Morchella are principally responsible for its antioxidant activity. This paper reviews the extraction, purification, structural analysis and antioxidant activity of Morchella polysaccharides (MPs), providing updated research progress. Meanwhile, the structural-property relations...
Source: International Journal of Biological Macromolecules - March 7, 2024 Category: Biochemistry Authors: Jinfeng Tian Zhe Zhang Yuanhong Shang Yi Zheng Source Type: research
Sporoderm-broken spores of Ganoderma lucidum modulate hepatoblastoma malignancy by regulating RACK1-mediated autophagy and tumour immunity
In conclusion, SBSGL had immunomodulatory effects and regulated the malignancy and autophagy of HB by regulating the O-GlcNAcylation of RACK1. These findings suggest that SBSGL holds promise as a potential anticancer drug for HB treatment.PMID:38451046 | DOI:10.1111/jcmm.18223 (Source: J Cell Mol Med)
Source: J Cell Mol Med - March 7, 2024 Category: Molecular Biology Authors: Rui Shen Yang Ge Yunpeng Qin Hang Gao Hongyan Yu Huazhang Wu Hang Song Source Type: research
Sporoderm-broken spores of Ganoderma lucidum modulate hepatoblastoma malignancy by regulating RACK1-mediated autophagy and tumour immunity
In conclusion, SBSGL had immunomodulatory effects and regulated the malignancy and autophagy of HB by regulating the O-GlcNAcylation of RACK1. These findings suggest that SBSGL holds promise as a potential anticancer drug for HB treatment.PMID:38451046 | DOI:10.1111/jcmm.18223 (Source: Molecular Medicine)
Source: Molecular Medicine - March 7, 2024 Category: Molecular Biology Authors: Rui Shen Yang Ge Yunpeng Qin Hang Gao Hongyan Yu Huazhang Wu Hang Song Source Type: research
Extraction, structure and antioxidant activity of the polysaccharides from morels (Morchella spp.): A review
Int J Biol Macromol. 2024 Mar 5:130656. doi: 10.1016/j.ijbiomac.2024.130656. Online ahead of print.ABSTRACTMorels (Morchella spp.), which are cultivated only in a few regions of the world, are edible mushrooms known for their various properties including antioxidation, immune regulation, antiinflammation, and antitumor effects. Polysaccharides from Morchella are principally responsible for its antioxidant activity. This paper reviews the extraction, purification, structural analysis and antioxidant activity of Morchella polysaccharides (MPs), providing updated research progress. Meanwhile, the structural-property relations...
Source: International Journal of Biological Macromolecules - March 7, 2024 Category: Biochemistry Authors: Jinfeng Tian Zhe Zhang Yuanhong Shang Yi Zheng Source Type: research
Molecules, Vol. 29, Pages 1195: Research Progress of Bioactive Components in Sanghuangporus spp.
In conclusion, we substantiate Sanghuang as a functional food by comprehensively presenting information on extraction and purification methods, component medical and structural properties, and nontoxicity, hoping to benefit the development of Sanghuang species as a group of functional food. (Source: Molecules)
Source: Molecules - March 7, 2024 Category: Chemistry Authors: Jungu Lu Manman Su Xuan Zhou Deming Li Xinhui Niu Yi Wang Tags: Review Source Type: research
Efficient conversion of cane molasses into Tremella fuciformis polysaccharides with enhanced bioactivity through repeated batch culture
In conclusion, this study lays the foundation for the efficient conversion of cane molasses and production of TFPS with high bioactivity.PMID:38432273 | DOI:10.1016/j.ijbiomac.2024.130536 (Source: International Journal of Biological Macromolecules)
Source: International Journal of Biological Macromolecules - March 3, 2024 Category: Biochemistry Authors: Caiyuan Yu Haipeng Zhu Yan Fang Yibin Qiu Peng Lei Hong Xu Qi Zhang Sha Li Source Type: research
Efficient conversion of cane molasses into Tremella fuciformis polysaccharides with enhanced bioactivity through repeated batch culture
In conclusion, this study lays the foundation for the efficient conversion of cane molasses and production of TFPS with high bioactivity.PMID:38432273 | DOI:10.1016/j.ijbiomac.2024.130536 (Source: International Journal of Biological Macromolecules)
Source: International Journal of Biological Macromolecules - March 3, 2024 Category: Biochemistry Authors: Caiyuan Yu Haipeng Zhu Yan Fang Yibin Qiu Peng Lei Hong Xu Qi Zhang Sha Li Source Type: research
Molecules, Vol. 29, Pages 1133: Pulp or Peel? Comparative Analysis of the Phytochemical Content and Selected Cosmetic-Related Properties of Annona cherimola L., Diospyros kaki Thumb., Cydonia oblonga Mill. and Fortunella margarita Swingle Pulp and Peel Extracts
eł-Bęben
Fruit peels might be a valuable source of active ingredients for cosmetics, leading to more sustainable usage of plant by-products. The aim of the study was to evaluate the phytochemical content and selected biological properties of hydroglycolic extracts from peels and pulps of Annona cherimola, Diospyros kaki, Cydonia oblonga, and Fortunella margarita as potential cosmetic ingredients. Peel and pulp extracts were compared for their antiradical activity (using DPPH and ABTS radical scavenging assays), skin-lightening potential (tyrosinase inhibitory assay), sun protection factor (SPF), and cytotoxicity towa...
Source: Molecules - March 3, 2024 Category: Chemistry Authors: Magdalena Lasota Paulina Lechwar Wirginia Kukula-Koch Marcin Czop Karolina Czech Katarzyna Gawe ł-Bęben Tags: Article Source Type: research
