Bilateral sequential nonarteritic anterior ischemic optic neuropathy associated with methamphetamine abuse
Can J Ophthalmol. 2024 Apr 2:S0008-4182(24)00066-8. doi: 10.1016/j.jcjo.2024.03.001. Online ahead of print.NO ABSTRACTPMID:38580216 | DOI:10.1016/j.jcjo.2024.03.001 (Source: Canadian Journal of Ophthalmology)
Source: Canadian Journal of Ophthalmology - April 5, 2024 Category: Opthalmology Authors: Caroline C Cotton Nancy F Vilar Source Type: research
Toxic-Induced Encephalopathy Following Chemsex in a Young HIV-Positive Male: A Complex Case of Acute Cognitive Impairment with Anterograde Amnesia and Behavioral Alterations
ConclusionsThe detailed analysis of this case underpins the severe neurological consequences that can manifest from heavy substance use. Comprehensive diagnostic evaluations, including neuroimaging and neuropsychological assessments, are crucial in elucidating the full spectrum of substance-induced cognitive impairments. There is an urgent need for enhanced public awareness and preventative measures, especially in the context of chemsex, to bring forth multifaceted health, social, and government implications that modern society must adeptly navigate. (Source: Infectious Diseases and Therapy)
Source: Infectious Diseases and Therapy - April 3, 2024 Category: Infectious Diseases Source Type: research
Overdose from Unintentional Fentanyl Use when Intending to Use a Non-opioid Substance: An Analysis of Medically Attended Opioid Overdose Events
AbstractFentanyl-mixed and substituted heroin is well-documented, but less is known about unintentional fentanyl use among people using stimulants. To determine the prevalence of and racial and ethnic disparities in unintentional fentanyl use among people experiencing a medically attended opioid overdose, we reviewed 448 suspected non-fatal overdose cases attended by a community paramedic overdose response team in San Francisco from June to September 2022. We applied a case definition for opioid overdose to paramedic records and abstracted data on intended substance use prior to overdose. Among events meeting case criteria...
Source: Journal of Urban Health - April 3, 2024 Category: Health Management Source Type: research
Toxic-Induced Encephalopathy Following Chemsex in a Young HIV-Positive Male: A Complex Case of Acute Cognitive Impairment with Anterograde Amnesia and Behavioral Alterations
ConclusionsThe detailed analysis of this case underpins the severe neurological consequences that can manifest from heavy substance use. Comprehensive diagnostic evaluations, including neuroimaging and neuropsychological assessments, are crucial in elucidating the full spectrum of substance-induced cognitive impairments. There is an urgent need for enhanced public awareness and preventative measures, especially in the context of chemsex, to bring forth multifaceted health, social, and government implications that modern society must adeptly navigate. (Source: Infectious Diseases and Therapy)
Source: Infectious Diseases and Therapy - April 3, 2024 Category: Infectious Diseases Source Type: research
DPP-4 inhibitors sitagliptin and PF-00734,200 mitigate dopaminergic neurodegeneration, neuroinflammation and behavioral impairment in the rat 6-OHDA model of Parkinson ’s disease
In conclusion, these studies support further evaluation of the repurposing of clinically approved gliptins as a treatment strategy for PD. (Source: AGE)
Source: AGE - April 2, 2024 Category: Geriatrics Source Type: research
An Evaluation of the Clinical Tools Used to Monitor Illicit Methamphetamine Use Among Chronic Pain Patients: A Cross Sectional Retrospective Study
Discussion: Confirmatory testing with mass spectrometry can detect illicit drugs, such as methamphetamine, with high sensitivity and specificity and should be used with all samples given the low sensitivity of screening immunoassay. It is of utmost importance that opioid pain medicine prescribers know the many possible interpretations of these results so that they are equipped to make appropriate clinical decisions to ensure the safety of the patient, prescriber, and practice.PMID:38560537 | PMC:PMC10977063 | DOI:10.1177/00185787231174752 (Source: Pain Physician)
Source: Pain Physician - April 1, 2024 Category: Anesthesiology Authors: Danielle R Schalk Jamie L Lewis Source Type: research
An Evaluation of the Clinical Tools Used to Monitor Illicit Methamphetamine Use Among Chronic Pain Patients: A Cross Sectional Retrospective Study
Discussion: Confirmatory testing with mass spectrometry can detect illicit drugs, such as methamphetamine, with high sensitivity and specificity and should be used with all samples given the low sensitivity of screening immunoassay. It is of utmost importance that opioid pain medicine prescribers know the many possible interpretations of these results so that they are equipped to make appropriate clinical decisions to ensure the safety of the patient, prescriber, and practice.PMID:38560537 | PMC:PMC10977063 | DOI:10.1177/00185787231174752 (Source: Pain Physician)
Source: Pain Physician - April 1, 2024 Category: Anesthesiology Authors: Danielle R Schalk Jamie L Lewis Source Type: research
SMART Family and Friends: Feasibility and outcomes of a video-conference delivered intervention for families impacted by another's methamphetamine use
CONCLUSIONS: Results provide initial support for the feasibility and positive outcomes of the SMART Family and Friends program. These findings demonstrate the successful provision of a mutual-support group for affected families delivered via video-conferencing, and merit further sufficiently powered randomised-control-trials to evaluate efficacy.PMID:38548059 | DOI:10.1016/j.josat.2024.209355 (Source: Cancer Control)
Source: Cancer Control - March 28, 2024 Category: Cancer & Oncology Authors: Clare M Rushton Peter J Kelly Tamsin Thomas Alison K Beck Camilla Townsend Amanda L Baker Victoria Manning Angela Argent Frank P Deane Leanne Hides Brian Hitsman Richard Velleman Gill Velleman Briony Larance Source Type: research
Urban and agricultural influences on the coastal dissolved organic matter pool in the Algoa Bay estuaries
This study provides new insight into anthropogenic impact on the Algoa Bay system and demonstrates the utility of non-targeted tandem mass spectrometry as a sensitive tool for assessing the health of ecologically important coastal ecosystems and will serve as a valuable foundation for strategizing long-term monitoring efforts.PMID:38548083 | DOI:10.1016/j.chemosphere.2024.141782 (Source: Chemosphere)
Source: Chemosphere - March 28, 2024 Category: Chemistry Authors: Jarmo-Charles J Kalinski Xavier Siwe Noundou Daniel Petras Gwynneth F Matcher Alexandros Polyzois Allegra T Aron Emily C Gentry Thomas G Bornman Janine B Adams Rosemary A Dorrington Source Type: research
Urban and agricultural influences on the coastal dissolved organic matter pool in the Algoa Bay estuaries
This study provides new insight into anthropogenic impact on the Algoa Bay system and demonstrates the utility of non-targeted tandem mass spectrometry as a sensitive tool for assessing the health of ecologically important coastal ecosystems and will serve as a valuable foundation for strategizing long-term monitoring efforts.PMID:38548083 | DOI:10.1016/j.chemosphere.2024.141782 (Source: Chemosphere)
Source: Chemosphere - March 28, 2024 Category: Chemistry Authors: Jarmo-Charles J Kalinski Xavier Siwe Noundou Daniel Petras Gwynneth F Matcher Alexandros Polyzois Allegra T Aron Emily C Gentry Thomas G Bornman Janine B Adams Rosemary A Dorrington Source Type: research
Urban and agricultural influences on the coastal dissolved organic matter pool in the Algoa Bay estuaries
This study provides new insight into anthropogenic impact on the Algoa Bay system and demonstrates the utility of non-targeted tandem mass spectrometry as a sensitive tool for assessing the health of ecologically important coastal ecosystems and will serve as a valuable foundation for strategizing long-term monitoring efforts.PMID:38548083 | DOI:10.1016/j.chemosphere.2024.141782 (Source: Chemosphere)
Source: Chemosphere - March 28, 2024 Category: Chemistry Authors: Jarmo-Charles J Kalinski Xavier Siwe Noundou Daniel Petras Gwynneth F Matcher Alexandros Polyzois Allegra T Aron Emily C Gentry Thomas G Bornman Janine B Adams Rosemary A Dorrington Source Type: research
Urban and agricultural influences on the coastal dissolved organic matter pool in the Algoa Bay estuaries
This study provides new insight into anthropogenic impact on the Algoa Bay system and demonstrates the utility of non-targeted tandem mass spectrometry as a sensitive tool for assessing the health of ecologically important coastal ecosystems and will serve as a valuable foundation for strategizing long-term monitoring efforts.PMID:38548083 | DOI:10.1016/j.chemosphere.2024.141782 (Source: Chemosphere)
Source: Chemosphere - March 28, 2024 Category: Chemistry Authors: Jarmo-Charles J Kalinski Xavier Siwe Noundou Daniel Petras Gwynneth F Matcher Alexandros Polyzois Allegra T Aron Emily C Gentry Thomas G Bornman Janine B Adams Rosemary A Dorrington Source Type: research
Childhood abuse and craving in methamphetamine-dependent individuals: the mediating role of alexithymia
Eur Arch Psychiatry Clin Neurosci. 2024 Mar 26. doi: 10.1007/s00406-024-01775-2. Online ahead of print.ABSTRACTIndividuals with a history of childhood abuse (CA, including neglect and abuse by caregivers before the age of 18 years) have more severe substance dependence problems than those without a history of childhood abuse. However, whether a history of CA exacerbates craving and the mechanism of this effect remain largely unknown. The aim of this study was to explore the role of alexithymia in the effects of CA on craving in a large sample of methamphetamine-dependent individuals based on latent vulnerability theory. A ...
Source: European Archives of Psychiatry and Clinical Neuroscience - March 26, 2024 Category: Psychiatry Authors: Jiajing Chen Dong Mei Wang Yang Tian Rongrong Zhu Yuqing Li Lianglun Jia Fabing Fu Shanshan Tang Xiaotao Wang Li Wang Xiang Yang Zhang Source Type: research
