Effects of Herpud1 in Methamphetamine-Induced Neuronal Apoptosis
CONCLUSIONS: These results suggest that Herpud1 plays an essential role in METH-induced neuronal ERS and apoptosis and may represent a potential therapeutic gene target in METH-induced neurotoxicity.PMID:38299291 | DOI:10.2174/0109298673277857231221110453 (Source: Current Medicinal Chemistry)
Source: Current Medicinal Chemistry - February 1, 2024 Category: Chemistry Authors: Shuang Lu Yan Li Lewen Wang Kun Xiong Jie Yan Zhihao Zhai Weitao Yan Source Type: research
Methamphetamine-Induced Psychosis and Schizophrenia: A Call for Special Attention: Response to Zhu et al
Am J Psychiatry. 2024 Feb 1;181(2):168-169. doi: 10.1176/appi.ajp.20230522.NO ABSTRACTPMID:38298080 | DOI:10.1176/appi.ajp.20230522 (Source: The American Journal of Psychiatry)
Source: The American Journal of Psychiatry - February 1, 2024 Category: Psychiatry Authors: Eline B Rognli Anne H øye J ørgen G Bramness Source Type: research
Methamphetamine-Induced Psychosis and Schizophrenia: A Call for Special Attention
Am J Psychiatry. 2024 Feb 1;181(2):168. doi: 10.1176/appi.ajp.20230467.NO ABSTRACTPMID:38298079 | DOI:10.1176/appi.ajp.20230467 (Source: The American Journal of Psychiatry)
Source: The American Journal of Psychiatry - February 1, 2024 Category: Psychiatry Authors: Li Zhu Tong Ni Fanglin Guan Source Type: research
Methamphetamine-Induced Psychosis and Schizophrenia: A Call for Special Attention: Response to Zhu et al.
American Journal of Psychiatry,Volume 181, Issue 2, Page 168-169, February 01, 2024. (Source: American Journal of Psychiatry)
Source: American Journal of Psychiatry - February 1, 2024 Category: Psychiatry Authors: Eline B. Rognli Anne H øye J ørgen G. Bramness Source Type: research
Methamphetamine-Induced Psychosis and Schizophrenia: A Call for Special Attention
American Journal of Psychiatry,Volume 181, Issue 2, Page 168-168, February 01, 2024. (Source: American Journal of Psychiatry)
Source: American Journal of Psychiatry - February 1, 2024 Category: Psychiatry Authors: Li Zhu Tong Ni Fanglin Guan Source Type: research
GxE interaction effects of < em > HCRTR2 < /em > single nucleotide polymorphism and adverse childhood experiences on methamphetamine use disorder
Conclusion: HCRTR2 SNP rs2653349 has no significant impact on MUD risk, but ACEs may increase this risk. GxE results suggest that rs2653349 could offer protection against developing MUD in individuals experiencing multiple types of ACEs.PMID:38295363 | DOI:10.1080/00952990.2023.2297661 (Source: The American Journal of Drug and Alcohol Abuse)
Source: The American Journal of Drug and Alcohol Abuse - January 31, 2024 Category: Addiction Authors: Kai-Ting Chen Ming-Chyi Huang Chun Lin Hu-Ming Chang Chung-Feng Kao Source Type: research
Multiple diagnoses in the context of parallel epidemics: methamphetamine, opioid use disorder and psychiatric conditions
Taylor Zande, Albert Kopak, Norman Hoffmann Journal of Public Mental Health, Vol. ahead-of-print, No. ahead-of-print, pp.- The most recent wave of the opioid epidemic in the USA has been complicated by a sharp increase in methamphetamine use. In addition, many people classified with opioid use disorder (OUD) and methamphetamine use disorder (MUD) present indications of psychiatric conditions. These diagnoses are also highly prevalent among people who are admitted to jails, but research conducted with this population is limited, due in part to the challenges associated with gaining access to local detention centers. This p...
Source: Journal of Public Mental Health - January 30, 2024 Category: International Medicine & Public Health Authors: Taylor Zande Albert Kopak Norman Hoffmann Source Type: research
Neural complexity is increased after low doses of LSD, but not moderate to high doses of oral THC or methamphetamine
Neuropsychopharmacology, Published online: 29 January 2024; doi:10.1038/s41386-024-01809-2Neural complexity is increased after low doses of LSD, but not moderate to high doses of oral THC or methamphetamine (Source: Neuropsychopharmacology)
Source: Neuropsychopharmacology - January 29, 2024 Category: Neurology Authors: Conor H. Murray Joel Frohlich Connor J. Haggarty Ilaria Tare Royce Lee Harriet de Wit Source Type: research
Comparison of brain functions between healthy participants and methamphetamine users with various addiction histories: Data analysis based on EEG and fNIRS
This study used 64-electrode EEG and fNIRS to conduct an experiment that analyzed the resting and craving states. The EEG and fNIRS data of 56 participants were collected, including 14 healthy participants, 14 methamphetamine users with an addiction history of 0.5 –5 years, 14 users with an addiction history of 5–10 years, and 14 users with an addiction history of 10–15 years. Isolated effective coherence (iCoh) within the brain network was used to process the EEG data. Statistical analysis was performed to compare differences in iCoh among the delta, t heta, alpha, beta, and gamma bands and explore oxyhemoglobin act...
Source: Journal of Innovative Optical Health Sciences - January 20, 2024 Category: Biomedical Science Authors: Xuelin Gu Xiaoou Li Banghua Yang Source Type: research
Methamphetamine Removal from Aquatic Environments by Magnetic Microrobots with Cyclodextrin Chiral Recognition Elements
The study explores the use of magnetic cyclodextrin (CD) functionalized microrobots for cleaning water contaminated with drug residues, specifically methamphetamine. These microrobots, with a hematite/magnetite core and CD surface, enhance pollutant removal due to their combined magnetic movement and hydrophobic cavities of CDs on microrobot surfaces. The design emphasizes autonomous movement, improved mass transfer, and targeted functionalization for effective remediation. AbstractThe growing consumption of drugs of abuse together with the inefficiency of the current wastewater treatment plants toward their presence has r...
Source: Small - January 19, 2024 Category: Nanotechnology Authors: Paula Mayorga –Burrezo,
Carmen C. Mayorga–Martinez,
Martin Kuchař,
Martin Pumera Tags: Research Article Source Type: research
Molecular mechanisms and treatment strategies for methamphetamine ‑induced neurodegeneration, inflammation and neurotoxicity
Acta Neurobiol Exp (Wars). 2023 Dec 28;83(4):414-431. doi: 10.55782/ane-2023-2488.ABSTRACTMethamphetamine (METH) is a highly addictive psychostimulant known for its profound impact on the nervous system. Chronic METH use leads to neurotoxicity characterized by various molecular and structural alterations in the brain. This review article primarily aims to elucidate the mechanisms underlying METH‑induced neurotoxicity. METH's mechanism of action involves the inhibition of dopamine, serotonin, and norepinephrine reuptake, resulting in altered synaptic function. Prolonged METH exposure triggers oxidative stress, endoplasmic...
Source: Acta Neurobiologiae Experimentalis - January 15, 2024 Category: Neurology Authors: Samareh Omidvari Zahra Azimzadeh Fariborz Rashnoo Foozhan Tahmasebinia Aliasghar Keramatinia Navid Ahmady Roozbahany Hojjat Allah Abbaszadeh Shahram Darabi Source Type: research
Molecular mechanisms and treatment strategies for methamphetamine ‑induced neurodegeneration, inflammation and neurotoxicity
Acta Neurobiol Exp (Wars). 2023 Dec 28;83(4):414-431. doi: 10.55782/ane-2023-2488.ABSTRACTMethamphetamine (METH) is a highly addictive psychostimulant known for its profound impact on the nervous system. Chronic METH use leads to neurotoxicity characterized by various molecular and structural alterations in the brain. This review article primarily aims to elucidate the mechanisms underlying METH‑induced neurotoxicity. METH's mechanism of action involves the inhibition of dopamine, serotonin, and norepinephrine reuptake, resulting in altered synaptic function. Prolonged METH exposure triggers oxidative stress, endoplasmic...
Source: Acta Neurobiologiae Experimentalis - January 15, 2024 Category: Neurology Authors: Samareh Omidvari Zahra Azimzadeh Fariborz Rashnoo Foozhan Tahmasebinia Aliasghar Keramatinia Navid Ahmady Roozbahany Hojjat Allah Abbaszadeh Shahram Darabi Source Type: research
Molecular mechanisms and treatment strategies for methamphetamine ‑induced neurodegeneration, inflammation and neurotoxicity
Acta Neurobiol Exp (Wars). 2023 Dec 28;83(4):414-431. doi: 10.55782/ane-2023-2488.ABSTRACTMethamphetamine (METH) is a highly addictive psychostimulant known for its profound impact on the nervous system. Chronic METH use leads to neurotoxicity characterized by various molecular and structural alterations in the brain. This review article primarily aims to elucidate the mechanisms underlying METH‑induced neurotoxicity. METH's mechanism of action involves the inhibition of dopamine, serotonin, and norepinephrine reuptake, resulting in altered synaptic function. Prolonged METH exposure triggers oxidative stress, endoplasmic...
Source: Acta Neurobiologiae Experimentalis - January 15, 2024 Category: Neurology Authors: Samareh Omidvari Zahra Azimzadeh Fariborz Rashnoo Foozhan Tahmasebinia Aliasghar Keramatinia Navid Ahmady Roozbahany Hojjat Allah Abbaszadeh Shahram Darabi Source Type: research
Molecular mechanisms and treatment strategies for methamphetamine ‑induced neurodegeneration, inflammation and neurotoxicity
Acta Neurobiol Exp (Wars). 2023 Dec 28;83(4):414-431. doi: 10.55782/ane-2023-2488.ABSTRACTMethamphetamine (METH) is a highly addictive psychostimulant known for its profound impact on the nervous system. Chronic METH use leads to neurotoxicity characterized by various molecular and structural alterations in the brain. This review article primarily aims to elucidate the mechanisms underlying METH‑induced neurotoxicity. METH's mechanism of action involves the inhibition of dopamine, serotonin, and norepinephrine reuptake, resulting in altered synaptic function. Prolonged METH exposure triggers oxidative stress, endoplasmic...
Source: Acta Neurobiologiae Experimentalis - January 15, 2024 Category: Neurology Authors: Samareh Omidvari Zahra Azimzadeh Fariborz Rashnoo Foozhan Tahmasebinia Aliasghar Keramatinia Navid Ahmady Roozbahany Hojjat Allah Abbaszadeh Shahram Darabi Source Type: research
Molecular mechanisms and treatment strategies for methamphetamine ‑induced neurodegeneration, inflammation and neurotoxicity
Acta Neurobiol Exp (Wars). 2023 Dec 28;83(4):414-431. doi: 10.55782/ane-2023-2488.ABSTRACTMethamphetamine (METH) is a highly addictive psychostimulant known for its profound impact on the nervous system. Chronic METH use leads to neurotoxicity characterized by various molecular and structural alterations in the brain. This review article primarily aims to elucidate the mechanisms underlying METH‑induced neurotoxicity. METH's mechanism of action involves the inhibition of dopamine, serotonin, and norepinephrine reuptake, resulting in altered synaptic function. Prolonged METH exposure triggers oxidative stress, endoplasmic...
Source: Acta Neurobiologiae Experimentalis - January 15, 2024 Category: Neurology Authors: Samareh Omidvari Zahra Azimzadeh Fariborz Rashnoo Foozhan Tahmasebinia Aliasghar Keramatinia Navid Ahmady Roozbahany Hojjat Allah Abbaszadeh Shahram Darabi Source Type: research
