Molecular mechanisms and treatment strategies for methamphetamine ‑induced neurodegeneration, inflammation and neurotoxicity
Acta Neurobiol Exp (Wars). 2023 Dec 28;83(4):414-431. doi: 10.55782/ane-2023-2488.ABSTRACTMethamphetamine (METH) is a highly addictive psychostimulant known for its profound impact on the nervous system. Chronic METH use leads to neurotoxicity characterized by various molecular and structural alterations in the brain. This review article primarily aims to elucidate the mechanisms underlying METH‑induced neurotoxicity. METH's mechanism of action involves the inhibition of dopamine, serotonin, and norepinephrine reuptake, resulting in altered synaptic function. Prolonged METH exposure triggers oxidative stress, endoplasmic...
Source: Acta Neurobiologiae Experimentalis - January 15, 2024 Category: Neurology Authors: Samareh Omidvari Zahra Azimzadeh Fariborz Rashnoo Foozhan Tahmasebinia Aliasghar Keramatinia Navid Ahmady Roozbahany Hojjat Allah Abbaszadeh Shahram Darabi Source Type: research

Molecular mechanisms and treatment strategies for methamphetamine ‑induced neurodegeneration, inflammation and neurotoxicity
Acta Neurobiol Exp (Wars). 2023 Dec 28;83(4):414-431. doi: 10.55782/ane-2023-2488.ABSTRACTMethamphetamine (METH) is a highly addictive psychostimulant known for its profound impact on the nervous system. Chronic METH use leads to neurotoxicity characterized by various molecular and structural alterations in the brain. This review article primarily aims to elucidate the mechanisms underlying METH‑induced neurotoxicity. METH's mechanism of action involves the inhibition of dopamine, serotonin, and norepinephrine reuptake, resulting in altered synaptic function. Prolonged METH exposure triggers oxidative stress, endoplasmic...
Source: Acta Neurobiologiae Experimentalis - January 15, 2024 Category: Neurology Authors: Samareh Omidvari Zahra Azimzadeh Fariborz Rashnoo Foozhan Tahmasebinia Aliasghar Keramatinia Navid Ahmady Roozbahany Hojjat Allah Abbaszadeh Shahram Darabi Source Type: research

Molecular mechanisms and treatment strategies for methamphetamine ‑induced neurodegeneration, inflammation and neurotoxicity
Acta Neurobiol Exp (Wars). 2023 Dec 28;83(4):414-431. doi: 10.55782/ane-2023-2488.ABSTRACTMethamphetamine (METH) is a highly addictive psychostimulant known for its profound impact on the nervous system. Chronic METH use leads to neurotoxicity characterized by various molecular and structural alterations in the brain. This review article primarily aims to elucidate the mechanisms underlying METH‑induced neurotoxicity. METH's mechanism of action involves the inhibition of dopamine, serotonin, and norepinephrine reuptake, resulting in altered synaptic function. Prolonged METH exposure triggers oxidative stress, endoplasmic...
Source: Acta Neurobiologiae Experimentalis - January 15, 2024 Category: Neurology Authors: Samareh Omidvari Zahra Azimzadeh Fariborz Rashnoo Foozhan Tahmasebinia Aliasghar Keramatinia Navid Ahmady Roozbahany Hojjat Allah Abbaszadeh Shahram Darabi Source Type: research

Molecular mechanisms and treatment strategies for methamphetamine ‑induced neurodegeneration, inflammation and neurotoxicity
Acta Neurobiol Exp (Wars). 2023 Dec 28;83(4):414-431. doi: 10.55782/ane-2023-2488.ABSTRACTMethamphetamine (METH) is a highly addictive psychostimulant known for its profound impact on the nervous system. Chronic METH use leads to neurotoxicity characterized by various molecular and structural alterations in the brain. This review article primarily aims to elucidate the mechanisms underlying METH‑induced neurotoxicity. METH's mechanism of action involves the inhibition of dopamine, serotonin, and norepinephrine reuptake, resulting in altered synaptic function. Prolonged METH exposure triggers oxidative stress, endoplasmic...
Source: Acta Neurobiologiae Experimentalis - January 15, 2024 Category: Neurology Authors: Samareh Omidvari Zahra Azimzadeh Fariborz Rashnoo Foozhan Tahmasebinia Aliasghar Keramatinia Navid Ahmady Roozbahany Hojjat Allah Abbaszadeh Shahram Darabi Source Type: research

Molecular mechanisms and treatment strategies for methamphetamine ‑induced neurodegeneration, inflammation and neurotoxicity
Acta Neurobiol Exp (Wars). 2023 Dec 28;83(4):414-431. doi: 10.55782/ane-2023-2488.ABSTRACTMethamphetamine (METH) is a highly addictive psychostimulant known for its profound impact on the nervous system. Chronic METH use leads to neurotoxicity characterized by various molecular and structural alterations in the brain. This review article primarily aims to elucidate the mechanisms underlying METH‑induced neurotoxicity. METH's mechanism of action involves the inhibition of dopamine, serotonin, and norepinephrine reuptake, resulting in altered synaptic function. Prolonged METH exposure triggers oxidative stress, endoplasmic...
Source: Acta Neurobiologiae Experimentalis - January 15, 2024 Category: Neurology Authors: Samareh Omidvari Zahra Azimzadeh Fariborz Rashnoo Foozhan Tahmasebinia Aliasghar Keramatinia Navid Ahmady Roozbahany Hojjat Allah Abbaszadeh Shahram Darabi Source Type: research

Molecular mechanisms and treatment strategies for methamphetamine ‑induced neurodegeneration, inflammation and neurotoxicity
Acta Neurobiol Exp (Wars). 2023 Dec 28;83(4):414-431. doi: 10.55782/ane-2023-2488.ABSTRACTMethamphetamine (METH) is a highly addictive psychostimulant known for its profound impact on the nervous system. Chronic METH use leads to neurotoxicity characterized by various molecular and structural alterations in the brain. This review article primarily aims to elucidate the mechanisms underlying METH‑induced neurotoxicity. METH's mechanism of action involves the inhibition of dopamine, serotonin, and norepinephrine reuptake, resulting in altered synaptic function. Prolonged METH exposure triggers oxidative stress, endoplasmic...
Source: Acta Neurobiologiae Experimentalis - January 15, 2024 Category: Neurology Authors: Samareh Omidvari Zahra Azimzadeh Fariborz Rashnoo Foozhan Tahmasebinia Aliasghar Keramatinia Navid Ahmady Roozbahany Hojjat Allah Abbaszadeh Shahram Darabi Source Type: research

Molecular mechanisms and treatment strategies for methamphetamine ‑induced neurodegeneration, inflammation and neurotoxicity
Acta Neurobiol Exp (Wars). 2023 Dec 28;83(4):414-431. doi: 10.55782/ane-2023-2488.ABSTRACTMethamphetamine (METH) is a highly addictive psychostimulant known for its profound impact on the nervous system. Chronic METH use leads to neurotoxicity characterized by various molecular and structural alterations in the brain. This review article primarily aims to elucidate the mechanisms underlying METH‑induced neurotoxicity. METH's mechanism of action involves the inhibition of dopamine, serotonin, and norepinephrine reuptake, resulting in altered synaptic function. Prolonged METH exposure triggers oxidative stress, endoplasmic...
Source: Acta Neurobiologiae Experimentalis - January 15, 2024 Category: Neurology Authors: Samareh Omidvari Zahra Azimzadeh Fariborz Rashnoo Foozhan Tahmasebinia Aliasghar Keramatinia Navid Ahmady Roozbahany Hojjat Allah Abbaszadeh Shahram Darabi Source Type: research

Molecular mechanisms and treatment strategies for methamphetamine ‑induced neurodegeneration, inflammation and neurotoxicity
Acta Neurobiol Exp (Wars). 2023 Dec 28;83(4):414-431. doi: 10.55782/ane-2023-2488.ABSTRACTMethamphetamine (METH) is a highly addictive psychostimulant known for its profound impact on the nervous system. Chronic METH use leads to neurotoxicity characterized by various molecular and structural alterations in the brain. This review article primarily aims to elucidate the mechanisms underlying METH‑induced neurotoxicity. METH's mechanism of action involves the inhibition of dopamine, serotonin, and norepinephrine reuptake, resulting in altered synaptic function. Prolonged METH exposure triggers oxidative stress, endoplasmic...
Source: Acta Neurobiologiae Experimentalis - January 15, 2024 Category: Neurology Authors: Samareh Omidvari Zahra Azimzadeh Fariborz Rashnoo Foozhan Tahmasebinia Aliasghar Keramatinia Navid Ahmady Roozbahany Hojjat Allah Abbaszadeh Shahram Darabi Source Type: research

Molecular mechanisms and treatment strategies for methamphetamine ‑induced neurodegeneration, inflammation and neurotoxicity
Acta Neurobiol Exp (Wars). 2023 Dec 28;83(4):414-431. doi: 10.55782/ane-2023-2488.ABSTRACTMethamphetamine (METH) is a highly addictive psychostimulant known for its profound impact on the nervous system. Chronic METH use leads to neurotoxicity characterized by various molecular and structural alterations in the brain. This review article primarily aims to elucidate the mechanisms underlying METH‑induced neurotoxicity. METH's mechanism of action involves the inhibition of dopamine, serotonin, and norepinephrine reuptake, resulting in altered synaptic function. Prolonged METH exposure triggers oxidative stress, endoplasmic...
Source: Acta Neurobiologiae Experimentalis - January 15, 2024 Category: Neurology Authors: Samareh Omidvari Zahra Azimzadeh Fariborz Rashnoo Foozhan Tahmasebinia Aliasghar Keramatinia Navid Ahmady Roozbahany Hojjat Allah Abbaszadeh Shahram Darabi Source Type: research

Molecular mechanisms and treatment strategies for methamphetamine ‑induced neurodegeneration, inflammation and neurotoxicity
Acta Neurobiol Exp (Wars). 2023 Dec 28;83(4):414-431. doi: 10.55782/ane-2023-2488.ABSTRACTMethamphetamine (METH) is a highly addictive psychostimulant known for its profound impact on the nervous system. Chronic METH use leads to neurotoxicity characterized by various molecular and structural alterations in the brain. This review article primarily aims to elucidate the mechanisms underlying METH‑induced neurotoxicity. METH's mechanism of action involves the inhibition of dopamine, serotonin, and norepinephrine reuptake, resulting in altered synaptic function. Prolonged METH exposure triggers oxidative stress, endoplasmic...
Source: Acta Neurobiologiae Experimentalis - January 15, 2024 Category: Neurology Authors: Samareh Omidvari Zahra Azimzadeh Fariborz Rashnoo Foozhan Tahmasebinia Aliasghar Keramatinia Navid Ahmady Roozbahany Hojjat Allah Abbaszadeh Shahram Darabi Source Type: research

Molecular mechanisms and treatment strategies for methamphetamine ‑induced neurodegeneration, inflammation and neurotoxicity
Acta Neurobiol Exp (Wars). 2023 Dec 28;83(4):414-431. doi: 10.55782/ane-2023-2488.ABSTRACTMethamphetamine (METH) is a highly addictive psychostimulant known for its profound impact on the nervous system. Chronic METH use leads to neurotoxicity characterized by various molecular and structural alterations in the brain. This review article primarily aims to elucidate the mechanisms underlying METH‑induced neurotoxicity. METH's mechanism of action involves the inhibition of dopamine, serotonin, and norepinephrine reuptake, resulting in altered synaptic function. Prolonged METH exposure triggers oxidative stress, endoplasmic...
Source: Acta Neurobiologiae Experimentalis - January 15, 2024 Category: Neurology Authors: Samareh Omidvari Zahra Azimzadeh Fariborz Rashnoo Foozhan Tahmasebinia Aliasghar Keramatinia Navid Ahmady Roozbahany Hojjat Allah Abbaszadeh Shahram Darabi Source Type: research

Molecular mechanisms and treatment strategies for methamphetamine ‑induced neurodegeneration, inflammation and neurotoxicity
Acta Neurobiol Exp (Wars). 2023 Dec 28;83(4):414-431. doi: 10.55782/ane-2023-2488.ABSTRACTMethamphetamine (METH) is a highly addictive psychostimulant known for its profound impact on the nervous system. Chronic METH use leads to neurotoxicity characterized by various molecular and structural alterations in the brain. This review article primarily aims to elucidate the mechanisms underlying METH‑induced neurotoxicity. METH's mechanism of action involves the inhibition of dopamine, serotonin, and norepinephrine reuptake, resulting in altered synaptic function. Prolonged METH exposure triggers oxidative stress, endoplasmic...
Source: Acta Neurobiologiae Experimentalis - January 15, 2024 Category: Neurology Authors: Samareh Omidvari Zahra Azimzadeh Fariborz Rashnoo Foozhan Tahmasebinia Aliasghar Keramatinia Navid Ahmady Roozbahany Hojjat Allah Abbaszadeh Shahram Darabi Source Type: research

Molecular mechanisms and treatment strategies for methamphetamine ‑induced neurodegeneration, inflammation and neurotoxicity
Acta Neurobiol Exp (Wars). 2023 Dec 28;83(4):414-431. doi: 10.55782/ane-2023-2488.ABSTRACTMethamphetamine (METH) is a highly addictive psychostimulant known for its profound impact on the nervous system. Chronic METH use leads to neurotoxicity characterized by various molecular and structural alterations in the brain. This review article primarily aims to elucidate the mechanisms underlying METH‑induced neurotoxicity. METH's mechanism of action involves the inhibition of dopamine, serotonin, and norepinephrine reuptake, resulting in altered synaptic function. Prolonged METH exposure triggers oxidative stress, endoplasmic...
Source: Acta Neurobiologiae Experimentalis - January 15, 2024 Category: Neurology Authors: Samareh Omidvari Zahra Azimzadeh Fariborz Rashnoo Foozhan Tahmasebinia Aliasghar Keramatinia Navid Ahmady Roozbahany Hojjat Allah Abbaszadeh Shahram Darabi Source Type: research

Molecular mechanisms and treatment strategies for methamphetamine ‑induced neurodegeneration, inflammation and neurotoxicity
Acta Neurobiol Exp (Wars). 2023 Dec 28;83(4):414-431. doi: 10.55782/ane-2023-2488.ABSTRACTMethamphetamine (METH) is a highly addictive psychostimulant known for its profound impact on the nervous system. Chronic METH use leads to neurotoxicity characterized by various molecular and structural alterations in the brain. This review article primarily aims to elucidate the mechanisms underlying METH‑induced neurotoxicity. METH's mechanism of action involves the inhibition of dopamine, serotonin, and norepinephrine reuptake, resulting in altered synaptic function. Prolonged METH exposure triggers oxidative stress, endoplasmic...
Source: Acta Neurobiologiae Experimentalis - January 15, 2024 Category: Neurology Authors: Samareh Omidvari Zahra Azimzadeh Fariborz Rashnoo Foozhan Tahmasebinia Aliasghar Keramatinia Navid Ahmady Roozbahany Hojjat Allah Abbaszadeh Shahram Darabi Source Type: research

Molecular mechanisms and treatment strategies for methamphetamine ‑induced neurodegeneration, inflammation and neurotoxicity
Acta Neurobiol Exp (Wars). 2023 Dec 28;83(4):414-431. doi: 10.55782/ane-2023-2488.ABSTRACTMethamphetamine (METH) is a highly addictive psychostimulant known for its profound impact on the nervous system. Chronic METH use leads to neurotoxicity characterized by various molecular and structural alterations in the brain. This review article primarily aims to elucidate the mechanisms underlying METH‑induced neurotoxicity. METH's mechanism of action involves the inhibition of dopamine, serotonin, and norepinephrine reuptake, resulting in altered synaptic function. Prolonged METH exposure triggers oxidative stress, endoplasmic...
Source: Acta Neurobiologiae Experimentalis - January 15, 2024 Category: Neurology Authors: Samareh Omidvari Zahra Azimzadeh Fariborz Rashnoo Foozhan Tahmasebinia Aliasghar Keramatinia Navid Ahmady Roozbahany Hojjat Allah Abbaszadeh Shahram Darabi Source Type: research