Single Cell Opioid Responses in the Context of HIV (SCORCH) Program Expansion: CNS Data Generation for Chronic Opioid, Methamphetamine, Cocaine and/or Cannabinoid Exposures (U01 - Clinical Trial Not Allowed)
Funding Opportunity RFA-DA-23-004 from the NIH Guide for Grants and Contracts. This initiative will support exploitation of single cell technologies (transcriptome, epigenome, nucleome, and other emerging single cell assays) to identify the unique molecular features of cells involved in SUDs and/or HIV replication, latency, or reservoirs. (Source: NIH Funding Opportunities (Notices, PA, RFA))
Source: NIH Funding Opportunities (Notices, PA, RFA) - March 15, 2022 Category: Research Source Type: funding

Investigating Transposable Elements and Mobile DNA as Targets of Integration for Establishing HIV Reservoirs in the Brain (R61/R33 - Clinical Trial Optional)
Funding Opportunity RFA-DA-23-003 from the NIH Guide for Grants and Contracts. oMany substances of abuse, including cocaine, methamphetamine, and several opioids exert powerful environmental insults on genomic DNA in the brain that induce expression of transposable elements and other mobile DNA. Transposable elements and mobile DNA, which comprise almost 50% of the human genome, are typically silenced through strong epigenetic modifications. When transposable elements and mobile DNA become active in people who use drugs of abuse, they potentially provide multiple integration sites for HIV in microglia. HIV integration i...
Source: NIH Funding Opportunities (Notices, PA, RFA) - February 11, 2022 Category: Research Source Type: funding

Organoid Modeling of Neural Stimulants and HIV Comorbidity of Human Brain (R01- Clinical Trial Optional)
Funding Opportunity RFA-DA-22-009 from the NIH Guide for Grants and Contracts. This Funding Opportunity Announcement (FOA) invites grant applications to study mechanisms underlying the neuropathophysiology of HIV-associated neurological disorders (HAND) using induced microglia and cerebral organoids generated from human derived induced pluripotent stem cell (iPSC) lines. Specific emphasis is on the comorbidity of HIV and neural stimulants, including amphetamine, methamphetamine, cocaine, and nicotine, studied at the single cell and neural circuits levels. (Source: NIH Funding Opportunities (Notices, PA, RFA))
Source: NIH Funding Opportunities (Notices, PA, RFA) - June 17, 2021 Category: Research Source Type: funding

Comprehensive Addiction and Recovery Act (CARA) Local Drug Crises Grants
Grants to support community-level efforts to prevent opioid, methamphetamine, and prescription drug use among youth ages 12-18, including activities targeting rural areas and other underserved populations and communities. Geographic coverage: Nationwide -- Centers for Disease Control and Prevention, U.S. Department of Health and Human Services (Source: Funding opportunities via the Rural Health Information Hub)
Source: Funding opportunities via the Rural Health Information Hub - February 2, 2021 Category: American Health Source Type: funding

NIDA Translational Avant-Garde Award for Development of Medication to Treat Substance Use Disorders (UG3/UH3 Clinical Trial Optional)
Funding Opportunity PAR-21-092 from the NIH Guide for Grants and Contracts. The purpose of this award is to support outstanding basic and/or clinical researchers with the vision and expertise to translate research discoveries into medications for the treatment of Substance Use Disorders (SUDs) stemming from tobacco, cannabis, cocaine, methamphetamine, heroin, or prescription opiate use. Eligible applicants must demonstrate the ability to develop molecules with the potential to treat SUDs and advance them in the drug development continuum. The ultimate goal of this FOA is to bring molecules closer to FDA approval. (Sourc...
Source: NIH Funding Opportunities (Notices, PA, RFA) - December 21, 2020 Category: Research Source Type: funding

Notice to Add a Receipt Date to RFA-DA-21-019 Single Cell Opioid Responses in the Context of HIV (SCORCH) Program Expansion: CNS Data Generation for Chronic Opioid, Methamphetamine, and/or Cocaine Exposures (U01 Clinical Trial Not Allowed)
Notice NOT-DA-20-063 from the NIH Guide for Grants and Contracts (Source: NIH Funding Opportunities (Notices, PA, RFA))
Source: NIH Funding Opportunities (Notices, PA, RFA) - July 8, 2020 Category: Research Source Type: funding

Single Cell Opioid Responses in the Context of HIV (SCORCH) Program Expansion: CNS Data Generation for Chronic Opioid, Methamphetamine, and/or Cocaine Exposures (U01 Clinical Trial Not Allowed)
Funding Opportunity RFA-DA-21-019 from the NIH Guide for Grants and Contracts. To support generation of single cell RNA-sequencing data sets for at least one brain region relevant to persistent HIV infection and opioid, cocaine and/or methamphetamine use disorder (Source: NIH Funding Opportunities (Notices, PA, RFA))
Source: NIH Funding Opportunities (Notices, PA, RFA) - May 12, 2020 Category: Research Source Type: funding

Targeting Inflammasomes in Substance Abuse and HIV (R01 Clinical Trial Not Allowed)
Funding Opportunity RFA-DA-19-039 from the NIH Guide for Grants and Contracts. Neuroinflammation triggered by brain trauma, neurodegenerative diseases and neurotoxicant-induced CNS disorders initiates CNS innate immune responses that activate inflammasomes. Inflammasomes are high molecular weight complexes in the cytosol of stimulated immune cells that mediate the activation of inflammatory cascades. In response to insults, Nod-like receptors (NLRs) recruit adaptor proteins and caspase-1 to assemble inflammasomes and process the release of pro-inflammatory cytokines IL-1?, IL-18 and IL-33. Recent evidence suggests that ...
Source: NIH Funding Opportunities (Notices, PA, RFA) - April 4, 2019 Category: Research Source Type: funding

NIDA Translational Avant-Garde Award for Development of Medication to Treat Substance Use Disorders (UG3/UH3, Clinical Trial Optional)
Funding Opportunity RFA-DA-18-020 from the NIH Guide for Grants and Contracts. The purpose of this award is to support outstanding basic and/or clinical researchers with the vision and expertise to translate research discoveries into medications for the treatment of Substance Use Disorders (SUDs) stemming from tobacco, cannabis, cocaine, methamphetamine, heroin, or prescription opiate use. Eligible applicants must demonstrate the ability to develop molecules with the potential to treat SUDs and advance them in the drug development continuum. The ultimate goal of this FOA is to bring molecules closer to FDA approval. (So...
Source: NIH Funding Opportunities (Notices, PA, RFA) - December 6, 2017 Category: Research Source Type: funding

Wisconsin Opioid and Methamphetamine Treatment Centers Grant
Funding to create opioid treatment and methamphetamine treatment centers in underserved areas of Wisconsin. Geographic coverage: Wisconsin -- Wisconsin Department of Health Services (Source: Funding opportunities via the Rural Health Information Hub)
Source: Funding opportunities via the Rural Health Information Hub - October 5, 2017 Category: American Health Source Type: funding

NIDA Translational Avant-Garde Award for Development of Medication to Treat Substance Use Disorders (UG3/UH3)
Funding Opportunity ID: 292303 Opportunity Number: RFA-DA-18-003 Opportunity Title: NIDA Translational Avant-Garde Award for Development of Medication to Treat Substance Use Disorders (UG3/UH3)Opportunity Category: DiscretionaryOpportunity Category Explanation: Funding Instrument Type: Cooperative AgreementCategory of Funding Activity: EducationHealthCategory Explanation: CFDA Number(s): 93.279Eligible Applicants: State governmentsCounty governmentsCity or township governmentsSpecial district governmentsIndependent school districtsPublic and State controlled institutions of higher educationNative America...
Source: Grants.gov - March 9, 2017 Category: Research Tags: Education Health Source Type: funding

NIDA Translational Avant-Garde Award for Development of Medication to Treat Substance Use Disorders (UG3/UH3)
Funding Opportunity RFA-DA-18-003 from the NIH Guide for Grants and Contracts. The purpose of this award is to support outstanding basic and/or clinical researchers with the vision and expertise to translate research discoveries into medications for the treatment of Substance Use Disorders (SUDs) stemming from tobacco, cannabis, cocaine, methamphetamine, heroin, or prescription opiate use. Eligible applicants must demonstrate the ability to develop molecules with the potential to treat SUDs and advance them in the drug development continuum. The ultimate goal of this FOA is to bring molecules closer to FDA approval. The...
Source: NIH Funding Opportunities (Notices, PA, RFA) - March 8, 2017 Category: Research Source Type: funding

Methamphetamine and Suicide Prevention Initiative - Generation Indigenous (GEN-I) Initiative Support
Awards funding to organizations in the Navajo, Phoenix, and Tucson areas that promote Native American youth development and family engagement through early intervention strategies to reduce risk factors linked to suicidal behavior and substance abuse. Geographic coverage: Arizona, New Mexico, and Utah -- Indian Health Service (Source: Funding opportunities via the Rural Health Information Hub)
Source: Funding opportunities via the Rural Health Information Hub - December 12, 2016 Category: American Health Source Type: funding

Division of Behavioral Health, Office of Clinical and Preventive Services, Methamphetamine and Suicide Prevention Initiative - Generation Indigenous (Gen-I) Initiative Support - Competing Supplement
Funding Opportunity ID: 285617 Opportunity Number: HHS-2016-IHS-MSPI-0002 Opportunity Title: Division of Behavioral Health, Office of Clinical and Preventive Services, Methamphetamine and Suicide Prevention Initiative - Generation Indigenous (Gen-I) Initiative Support - Competing SupplementOpportunity Category: DiscretionaryOpportunity Category Explanation: Funding Instrument Type: GrantCategory of Funding Activity: HealthCategory Explanation: CFDA Number(s): 93.933Eligible Applicants: Native American tribal governments (Federally recognized)Native American tribal organizations (o...
Source: Grants.gov - July 1, 2016 Category: Research Tags: Health Source Type: funding

Division of Behavioral Health, Office of Clinical and Preventive Services, Methamphetamine and Suicide Prevention Initiative - Generation Indigenous (Gen-I) Initiative Support - New
Funding Opportunity ID: 285596 Opportunity Number: HHS-2016-IHS-MSPI-0001 Opportunity Title: Division of Behavioral Health, Office of Clinical and Preventive Services, Methamphetamine and Suicide Prevention Initiative - Generation Indigenous (Gen-I) Initiative Support - NewOpportunity Category: DiscretionaryOpportunity Category Explanation: Funding Instrument Type: GrantCategory of Funding Activity: HealthCategory Explanation: CFDA Number(s): 93.933Eligible Applicants: Native American tribal governments (Federally recognized)Native American tribal organizations (other than Federal...
Source: Grants.gov - July 1, 2016 Category: Research Tags: Health Source Type: funding