How to differentiate between invasive lobular carcinoma metastasis and type 4 advanced gastric cancer: The importance of immunohistochemistry
Clin Case Rep. 2023 Jun 19;11(6):e7529. doi: 10.1002/ccr3.7529. eCollection 2023 Jun.ABSTRACTKEY CLINICAL MESSAGE: Gastric metastases derived from breast carcinomas and type 4 advanced gastric cancers are often difficult to distinguish because of their similar endoscopic and pathologic findings. Therefore, immunohistochemical analyses are key to diagnosis.ABSTRACT: Gastric metastases originating from breast carcinomas and type 4 advanced gastric cancers are often difficult to distinguish because of their similar endoscopic and pathologic characteristics. This often delays early intervention and accordingly affects prognosi...
Source: Clinical Genitourinary Cancer - June 22, 2023 Category: Cancer & Oncology Authors: Ryuhei Jinushi Tomonori Kawasaki Shomei Ryozawa Source Type: research
Cancers, Vol. 15, Pages 3299: Optimized Modeling of Metastatic Triple-Negative Invasive Lobular Breast Carcinoma
Cathrin Brisken
Invasive lobular carcinoma (ILC) is a common breast cancer subtype that is often diagnosed at advanced stages and causes significant morbidity. Late-onset secondary tumor recurrence affects up to 30% of ILC patients, posing a therapeutic challenge if resistance to systemic therapy develops. Nonetheless, there is a lack of preclinical models for ILC, and the current models do not accurately reproduce the complete range of the disease. We created clinically relevant metastatic xenografts to address this gap by grafting the triple-negative IPH-926 cell line into mouse milk ducts. The resulting intraductal ...
Source: Cancers - June 22, 2023 Category: Cancer & Oncology Authors: George Sflomos Nora Schaumann Matthias Christgen Henriette Christgen Stephan Bartels Hans Kreipe Laura Battista Cathrin Brisken Tags: Article Source Type: research
How to differentiate between invasive lobular carcinoma metastasis and type 4 advanced gastric cancer: The importance of immunohistochemistry
Immunohistochemical features of metastatic invasive lobular mammary carcinoma to the stomach. Key Clinical MessageGastric metastases derived from breast carcinomas and type 4 advanced gastric cancers are often difficult to distinguish because of their similar endoscopic and pathologic findings. Therefore, immunohistochemical analyses are key to diagnosis.AbstractGastric metastases originating from breast carcinomas and type 4 advanced gastric cancers are often difficult to distinguish because of their similar endoscopic and pathologic characteristics. This often delays early intervention and accordingly affects prognosis. ...
Source: Clinical Case Reports - June 20, 2023 Category: General Medicine Authors: Ryuhei Jinushi,
Tomonori Kawasaki,
Shomei Ryozawa Tags: CASE IMAGE Source Type: research
Cancers, Vol. 15, Pages 3239: Full-Dose Intraoperative Electron Radiotherapy for Early Breast Cancer: Evidence from a Single Center & rsquo;s Experience
Cancers, Vol. 15, Pages 3239: Full-Dose Intraoperative Electron Radiotherapy for Early Breast Cancer: Evidence from a Single Center’s Experience
Cancers doi: 10.3390/cancers15123239
Authors:
Antonio Stefanelli
Eleonora Farina
Edoardo Mastella
Sara Fabbri
Alessandro Turra
Simona Bonazza
Alessandro De Troia
Margherita K. Radica
Paolo Carcoforo
To evaluate the clinical response rate and cosmetic outcome after full-dose intraoperative electron radiotherapy (IOERT) in early breast cancer (BC) treated with conserving surgery. Inclusion criteria were: >60 years old, clinical tumor size...
Source: Cancers - June 19, 2023 Category: Cancer & Oncology Authors: Antonio Stefanelli Eleonora Farina Edoardo Mastella Sara Fabbri Alessandro Turra Simona Bonazza Alessandro De Troia Margherita K. Radica Paolo Carcoforo Tags: Article Source Type: research
A role for breast ultrasound Artificial Intelligence decision support in the evaluation of small invasive lobular carcinomas
CONCLUSION: The AI DS accurately characterized 100% of detected ILC lesions as suspicious or probably malignant. AI DS may be helpful in increasing radiologist confidence when assessing ILC on ultrasound.PMID:37311398 | DOI:10.1016/j.clinimag.2023.05.005 (Source: Clinical Breast Cancer)
Source: Clinical Breast Cancer - June 13, 2023 Category: Cancer & Oncology Authors: Tali Amir Kristen Coffey Varadan Sevilimedu Reza Fardanesh Victoria L Mango Source Type: research
A role for breast ultrasound Artificial Intelligence decision support in the evaluation of small invasive lobular carcinomas
CONCLUSION: The AI DS accurately characterized 100% of detected ILC lesions as suspicious or probably malignant. AI DS may be helpful in increasing radiologist confidence when assessing ILC on ultrasound.PMID:37311398 | DOI:10.1016/j.clinimag.2023.05.005 (Source: Clinical Genitourinary Cancer)
Source: Clinical Genitourinary Cancer - June 13, 2023 Category: Cancer & Oncology Authors: Tali Amir Kristen Coffey Varadan Sevilimedu Reza Fardanesh Victoria L Mango Source Type: research
Achieving Intraperitoneal Disease Control Using Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy: Two Cases of Metastatic Breast Cancer
In conclusion, CRS/HIPEC is safe and can provide intraperitoneal disease and symptom control in select patients with PMBC. Thus, CRS/HIPEC can be offered to these rare patients who have failed standard treatments.PMID:37303429 | PMC:PMC10250112 | DOI:10.7759/cureus.38767 (Source: Cancer Control)
Source: Cancer Control - June 12, 2023 Category: Cancer & Oncology Authors: Philipp Barakat Vadim Gushchin Luis Felipe Falla Zuniga Mary Caitlin King Armando Sardi Source Type: research
A study of clinical and molecular characteristics in bilateral primary breast cancer
ConclusionsOur study suggested that BPBC may tend to be lobular carcinoma and have the HR+/HER2 − subtype. Although our study did not find specific germline and somatic mutations in BPBC, more research is needed for verification. (Source: Cancer Medicine)
Source: Cancer Medicine - June 9, 2023 Category: Cancer & Oncology Authors: Bin Li,
Weiqi Xu,
Jianing Cao,
Duancheng Guo,
Zhonghua Tao,
Juan Jin,
Xichun Hu Tags: RESEARCH ARTICLE Source Type: research
Application of Breast Scintigraphy for Patients with Suspicious (Breast Imaging-Reporting and Data System IV) Breast Lesions
CONCLUSIONS: Breast scintigraphy with general purpose gamma camera employing SPECT imaging may assist the selection of BIRADS IV lesions in need for surgery. All uptake positive cases should undergo surgery and decision for uptake negative cases should be made based on other data.PMID:37288015 | PMC:PMC10241632 | DOI:10.4103/abr.abr_347_21 (Source: Biomed Res)
Source: Biomed Res - June 8, 2023 Category: Research Authors: Ali Reza Azarpeikan Ramesh Omranipour Habibollah Mahmoodzadeh Seyed Rouhollah Miri Narjes Mohammadzadeh Farhang Derakhshan Saeed Farzanefar Mehrshad Abbasi Source Type: research
Application of Breast Scintigraphy for Patients with Suspicious (Breast Imaging-Reporting and Data System IV) Breast Lesions
CONCLUSIONS: Breast scintigraphy with general purpose gamma camera employing SPECT imaging may assist the selection of BIRADS IV lesions in need for surgery. All uptake positive cases should undergo surgery and decision for uptake negative cases should be made based on other data.PMID:37288015 | PMC:PMC10241632 | DOI:10.4103/abr.abr_347_21 (Source: Adv Data)
Source: Adv Data - June 8, 2023 Category: Epidemiology Authors: Ali Reza Azarpeikan Ramesh Omranipour Habibollah Mahmoodzadeh Seyed Rouhollah Miri Narjes Mohammadzadeh Farhang Derakhshan Saeed Farzanefar Mehrshad Abbasi Source Type: research
Application of Breast Scintigraphy for Patients with Suspicious (Breast Imaging-Reporting and Data System IV) Breast Lesions
CONCLUSIONS: Breast scintigraphy with general purpose gamma camera employing SPECT imaging may assist the selection of BIRADS IV lesions in need for surgery. All uptake positive cases should undergo surgery and decision for uptake negative cases should be made based on other data.PMID:37288015 | PMC:PMC10241632 | DOI:10.4103/abr.abr_347_21 (Source: Biomed Res)
Source: Biomed Res - June 8, 2023 Category: Research Authors: Ali Reza Azarpeikan Ramesh Omranipour Habibollah Mahmoodzadeh Seyed Rouhollah Miri Narjes Mohammadzadeh Farhang Derakhshan Saeed Farzanefar Mehrshad Abbasi Source Type: research
Application of Breast Scintigraphy for Patients with Suspicious (Breast Imaging-Reporting and Data System IV) Breast Lesions
CONCLUSIONS: Breast scintigraphy with general purpose gamma camera employing SPECT imaging may assist the selection of BIRADS IV lesions in need for surgery. All uptake positive cases should undergo surgery and decision for uptake negative cases should be made based on other data.PMID:37288015 | PMC:PMC10241632 | DOI:10.4103/abr.abr_347_21 (Source: Adv Data)
Source: Adv Data - June 8, 2023 Category: Epidemiology Authors: Ali Reza Azarpeikan Ramesh Omranipour Habibollah Mahmoodzadeh Seyed Rouhollah Miri Narjes Mohammadzadeh Farhang Derakhshan Saeed Farzanefar Mehrshad Abbasi Source Type: research
A role for breast ultrasound artificial intelligence decision support in the evaluation of small invasive lobular carcinomas
To evaluate the diagnostic performance of an Artificial Intelligence (AI) decision support (DS) system in the ultrasound (US) assessment of invasive lobular carcinoma (ILC) of the breast, a cancer that can demonstrate variable appearance and present insidiously. (Source: Clinical Imaging)
Source: Clinical Imaging - May 16, 2023 Category: Radiology Authors: Tali Amir, Kristen Coffey, Varadan Sevilimedu, Reza Fardanesh, Victoria L. Mango Tags: Breast Imaging Source Type: research
High expression of RTN4IP1 predicts adverse prognosis for patients with breast cancer
CONCLUSIONS: Overexpressed in BC tissue, RTN4IP1 predicts adverse prognosis for patients with BC, especially in infiltrating ductal carcinoma, infiltrating lobular carcinoma, Stage II, Stages III&IV and luminal A subtype.PMID:37180657 | PMC:PMC10174766 | DOI:10.21037/tcr-22-2350 (Source: Cancer Control)
Source: Cancer Control - May 14, 2023 Category: Cancer & Oncology Authors: Xiu Wang Xinyu Li Wenying Jiang Source Type: research
Machine Learning Approach for the Determination of the Best Cut-Off Points for Ki67 Proliferation Index in Adjuvant and Neo-Adjuvant Therapy Breast Cancer Patients
CONCLUSION: Despite variability in measurement and cut-off points, the Ki-67 proliferation index is still helpful in the clinic. Further investigation is needed to determine the best cut-off points for different patients. The sensitivity and specificity of Ki-67 cutoff point prediction models in this study could further prove its significance as a prognostic factor.PMID:37156698 | DOI:10.1016/j.clbc.2023.03.015 (Source: Clinical Breast Cancer)
Source: Clinical Breast Cancer - May 8, 2023 Category: Cancer & Oncology Authors: Sepehr Khosravi Amirmahdi Khayyamfar Jamileh Karimi Mahdieh Tutuni Alireza Negahi Mohamad Esmaeil Akbari Nahid Nafissi Source Type: research
