Association of metastatic pattern in breast cancer with tumor and patient-specific factors: a nationwide autopsy study using artificial intelligence
CONCLUSION: This is the first large-scale study that demonstrates that artificial intelligence methods are efficient for IE from Dutch databanks. Different histological subtypes show different frequencies and combinations of metastatic sites which may reflect the underlying biology of metastatic breast cancer.PMID:38133738 | DOI:10.1007/s12282-023-01534-6 (Source: Breast Cancer)
Source: Breast Cancer - December 22, 2023 Category: Cancer & Oncology Authors: Fatemeh Kazemzadeh J A A Snoek Quirinus J Voorham Martijn G H van Oijen Niek Hugen Iris D Nagtegaal Source Type: research

Association of metastatic pattern in breast cancer with tumor and patient-specific factors: a nationwide autopsy study using artificial intelligence
CONCLUSION: This is the first large-scale study that demonstrates that artificial intelligence methods are efficient for IE from Dutch databanks. Different histological subtypes show different frequencies and combinations of metastatic sites which may reflect the underlying biology of metastatic breast cancer.PMID:38133738 | DOI:10.1007/s12282-023-01534-6 (Source: Breast Cancer)
Source: Breast Cancer - December 22, 2023 Category: Cancer & Oncology Authors: Fatemeh Kazemzadeh J A A Snoek Quirinus J Voorham Martijn G H van Oijen Niek Hugen Iris D Nagtegaal Source Type: research

Association of metastatic pattern in breast cancer with tumor and patient-specific factors: a nationwide autopsy study using artificial intelligence
CONCLUSION: This is the first large-scale study that demonstrates that artificial intelligence methods are efficient for IE from Dutch databanks. Different histological subtypes show different frequencies and combinations of metastatic sites which may reflect the underlying biology of metastatic breast cancer.PMID:38133738 | DOI:10.1007/s12282-023-01534-6 (Source: Breast Cancer)
Source: Breast Cancer - December 22, 2023 Category: Cancer & Oncology Authors: Fatemeh Kazemzadeh J A A Snoek Quirinus J Voorham Martijn G H van Oijen Niek Hugen Iris D Nagtegaal Source Type: research

Exploration of cancer associated fibroblasts phenotypes in the tumor microenvironment of classical and pleomorphic Invasive Lobular Carcinoma
ConclusionOur study explores multiple CAFs phenotypes between classical and pleomorphic ILC. We showed that CAFs subset differ between Classic ILC and Pleomorphic ILC. A-SMA CAFs are more prevalent in the TME of classic ILCs whereas Pleomorphic ILCs are dominated by CAFs without A-SMA expression. This also iterates the importance of exploring this particular type of breast carcinoma in more detail, paving the way for meaningful translational research. (Source: Frontiers in Oncology)
Source: Frontiers in Oncology - December 21, 2023 Category: Cancer & Oncology Source Type: research

Breast carcinoma arising in a fibroadenoma: A case series of 16  patients and review of the literature
Oncol Lett. 2023 Dec 1;27(1):39. doi: 10.3892/ol.2023.14172. eCollection 2024 Jan.ABSTRACTBreast carcinoma arising from a fibroadenoma is an uncommon entity and is frequently detected incidentally during pathological examination or excisional biopsy of a benign breast tumor. Due to only sporadic cases being reported, evidence-based guidelines are not well-established to date. The present report describes 16 patients diagnosed with breast carcinoma arising within a fibroadenoma in the Third Hospital of Nanchang (Nanchang, China) between January 2019 and December 2021 and discusses the clinicopathological characteristics, im...
Source: Oncology Letters - December 20, 2023 Category: Cancer & Oncology Authors: Liang Xu Shuya Luo Qixin Mao Yufeng Gao Lihua Luo Wei Qu Yali Cao Source Type: research

Lobular Neoplasia Diagnosed by MRI-Guided Breast Biopsy: Identifying Upgrade Rate to Malignancy and Outcomes of Clinical and Surgical Management
CONCLUSIONS: In this contemporary cohort of MRI-detected LNs, the upgrade rate was low. Omission of surgery for MRI-detected LNs in carefully selected patients may be considered in a shared decision-making capacity between the patient and the treatment team. Larger cohorts are needed to determine factors predictive of upgrade risk.PMID:38117388 | DOI:10.1245/s10434-023-14764-x (Source: Ann Oncol)
Source: Ann Oncol - December 20, 2023 Category: Cancer & Oncology Authors: Shlermine A Everidge Jia Sun Mediget Teshome Nina Tamirisa Susie Sun Taiwo Adesoye Emily Nia Therese Bevers Isabelle Bedrosian Miral Patel Puneet Singh Source Type: research

Breast carcinoma arising in a fibroadenoma: A case series of 16  patients and review of the literature
Oncol Lett. 2023 Dec 1;27(1):39. doi: 10.3892/ol.2023.14172. eCollection 2024 Jan.ABSTRACTBreast carcinoma arising from a fibroadenoma is an uncommon entity and is frequently detected incidentally during pathological examination or excisional biopsy of a benign breast tumor. Due to only sporadic cases being reported, evidence-based guidelines are not well-established to date. The present report describes 16 patients diagnosed with breast carcinoma arising within a fibroadenoma in the Third Hospital of Nanchang (Nanchang, China) between January 2019 and December 2021 and discusses the clinicopathological characteristics, im...
Source: Oncology Letters - December 20, 2023 Category: Cancer & Oncology Authors: Liang Xu Shuya Luo Qixin Mao Yufeng Gao Lihua Luo Wei Qu Yali Cao Source Type: research