ASO Visual Abstract: Is Choosing Wisely Wise for Lobular Carcinoma in Patients Over 70? A National Cancer Database (NCDB) Analysis of Sentinel Node Practice Patterns
Ann Surg Oncol. 2023 Aug 26. doi: 10.1245/s10434-023-13992-5. Online ahead of print.NO ABSTRACTPMID:37626253 | DOI:10.1245/s10434-023-13992-5 (Source: Ann Oncol)
Source: Ann Oncol - August 25, 2023 Category: Cancer & Oncology Authors: Nicole H Goldhaber Thomas O'Keefe Jessica Kang Sasha Douglas Sarah L Blair Source Type: research

Histologic heterogeneity predicts patient prognosis of HER2-positive metastatic breast cancer: A retrospective study based on SEER database
CONCLUSIONS: Histological subtypes are involved in determining the heterogeneity of HER2+ MBC patient prognosis, which is helpful to guide the prognosis prediction and monitoring of HER2+ breast cancer patients in clinics.PMID:37605516 | DOI:10.1002/cam4.6469 (Source: Cancer Control)
Source: Cancer Control - August 22, 2023 Category: Cancer & Oncology Authors: Yajie Wang Yiran Liang Fangzhou Ye Dan Luo Yuhan Jin Yaming Li Wenjing Zhao Bing Chen Lijuan Wang Qifeng Yang Source Type: research

Histologic heterogeneity predicts patient prognosis of HER2 ‐positive metastatic breast cancer: A retrospective study based on SEER database
ConclusionsHistological subtypes are involved in determining the heterogeneity of HER2+ MBC patient prognosis, which is helpful to guide the prognosis prediction and monitoring of HER2+ breast cancer patients in clinics. (Source: Cancer Medicine)
Source: Cancer Medicine - August 22, 2023 Category: Cancer & Oncology Authors: Yajie Wang, Yiran Liang, Fangzhou Ye, Dan Luo, Yuhan Jin, Yaming Li, Wenjing Zhao, Bing Chen, Lijuan Wang, Qifeng Yang Tags: RESEARCH ARTICLE Source Type: research

ASO Author Reflections: Menopausal Status Does Not Predict Successful Breast Conservation Surgery After Neoadjuvant Chemotherapy in Invasive Lobular Carcinoma
Ann Surg Oncol. 2023 Aug 10. doi: 10.1245/s10434-023-14131-w. Online ahead of print.NO ABSTRACTPMID:37561346 | DOI:10.1245/s10434-023-14131-w (Source: Ann Oncol)
Source: Ann Oncol - August 10, 2023 Category: Cancer & Oncology Authors: Kirithiga Ramalingam Rita Mukhtar Source Type: research

Successful Breast Conservation After Neoadjuvant Chemotherapy in Lobular Breast Cancer: The Role of Menopausal Status in Response to Treatment
CONCLUSION: NAC was not associated with successful BCS in either premenopausal or postmenopausal patients with ILC. Although premenopausal patients were more likely to receive NAC, these data suggest that menopausal status may not be a good predictor of response to chemotherapy. Better predictors of response and more efficacious treatment for patients with ILC are needed.PMID:37561345 | DOI:10.1245/s10434-023-14075-1 (Source: Ann Oncol)
Source: Ann Oncol - August 10, 2023 Category: Cancer & Oncology Authors: Kirithiga Ramalingam Elle Clelland Harriet Rothschild Firdows Mujir Helena Record Mandeep Kaur Rita A Mukhtar Source Type: research

ASO Author Reflections: Menopausal Status Does Not Predict Successful Breast Conservation Surgery After Neoadjuvant Chemotherapy in Invasive Lobular Carcinoma
Ann Surg Oncol. 2023 Aug 10. doi: 10.1245/s10434-023-14131-w. Online ahead of print.NO ABSTRACTPMID:37561346 | DOI:10.1245/s10434-023-14131-w (Source: Ann Oncol)
Source: Ann Oncol - August 10, 2023 Category: Cancer & Oncology Authors: Kirithiga Ramalingam Rita Mukhtar Source Type: research

Successful Breast Conservation After Neoadjuvant Chemotherapy in Lobular Breast Cancer: The Role of Menopausal Status in Response to Treatment
CONCLUSION: NAC was not associated with successful BCS in either premenopausal or postmenopausal patients with ILC. Although premenopausal patients were more likely to receive NAC, these data suggest that menopausal status may not be a good predictor of response to chemotherapy. Better predictors of response and more efficacious treatment for patients with ILC are needed.PMID:37561345 | DOI:10.1245/s10434-023-14075-1 (Source: Ann Oncol)
Source: Ann Oncol - August 10, 2023 Category: Cancer & Oncology Authors: Kirithiga Ramalingam Elle Clelland Harriet Rothschild Firdows Mujir Helena Record Mandeep Kaur Rita A Mukhtar Source Type: research

ASO Visual Abstract: Predictors of Early Versus Late Recurrence in Invasive Lobular Carcinoma of the Breast: Impact of Local and Systemic Therapy
Ann Surg Oncol. 2023 Aug 8. doi: 10.1245/s10434-023-14059-1. Online ahead of print.NO ABSTRACTPMID:37552350 | DOI:10.1245/s10434-023-14059-1 (Source: Ann Oncol)
Source: Ann Oncol - August 8, 2023 Category: Cancer & Oncology Authors: Harriet T Rothschild Elle N Clelland Firdows Mujir Helena Record Jasmine Wong Laura J Esserman Michael Alvarado Cheryl Ewing Rita A Mukhtar Source Type: research

A Look at the Other Side: High-Risk Lesions and Occult Contralateral Malignancy in Symmetry Procedures for Patients Undergoing Oncoplastic Breast-Conserving Surgery
CONCLUSION: The incidence of occult malignancy among OBCS symmetry procedures approaches 5%. The final pathology of excisional biopsies had a higher upgrade rate than previously reported. All identified malignancies were early-stage disease. The higher incidence of occult breast cancer in this population warrants the routine orientation of all specimens, which allows patients with incidental early-stage cancer the option of breast preservation.PMID:37535266 | DOI:10.1245/s10434-023-13894-6 (Source: Ann Oncol)
Source: Ann Oncol - August 3, 2023 Category: Cancer & Oncology Authors: Katherine M Jackson Janelle-Cheri Millen Javier I J Orozco Stacey L Stern Crystal E Fancher Janie G Grumley Source Type: research

A Look at the Other Side: High-Risk Lesions and Occult Contralateral Malignancy in Symmetry Procedures for Patients Undergoing Oncoplastic Breast-Conserving Surgery
CONCLUSION: The incidence of occult malignancy among OBCS symmetry procedures approaches 5%. The final pathology of excisional biopsies had a higher upgrade rate than previously reported. All identified malignancies were early-stage disease. The higher incidence of occult breast cancer in this population warrants the routine orientation of all specimens, which allows patients with incidental early-stage cancer the option of breast preservation.PMID:37535266 | DOI:10.1245/s10434-023-13894-6 (Source: Ann Oncol)
Source: Ann Oncol - August 3, 2023 Category: Cancer & Oncology Authors: Katherine M Jackson Janelle-Cheri Millen Javier I J Orozco Stacey L Stern Crystal E Fancher Janie G Grumley Source Type: research

A Look at the Other Side: High-Risk Lesions and Occult Contralateral Malignancy in Symmetry Procedures for Patients Undergoing Oncoplastic Breast-Conserving Surgery
ConclusionThe incidence of occult malignancy among OBCS symmetry procedures approaches 5%. The final pathology of excisional biopsies had a higher upgrade rate than previously reported. All identified malignancies were early-stage disease. The higher incidence of occult breast cancer in this population warrants the routine orientation of all specimens, which allows patients with incidental early-stage cancer the option of breast preservation. (Source: Annals of Surgical Oncology)
Source: Annals of Surgical Oncology - August 3, 2023 Category: Cancer & Oncology Source Type: research

Does Non-Classic Lobular Carcinoma In Situ at the Lumpectomy Margin Increase Local Recurrence?
CONCLUSIONS: For completely excised invasive breast cancers associated with NC-LCIS, extent of margin width for NC-LCIS was not associated with a difference in IBTR or LRR. These data suggest that the decision to perform reexcision of margin after lumpectomy should be driven by the invasive cancer, rather than the NC-LCIS margin.PMID:37493892 | DOI:10.1245/s10434-023-13899-1 (Source: Ann Oncol)
Source: Ann Oncol - July 26, 2023 Category: Cancer & Oncology Authors: Anna C Beck Solange Bayard George Plitas Varadan Sevilimedu M Gabriela Kuba Paula Garcia Monica Morrow Audree B Tadros Source Type: research

Does Non-Classic Lobular Carcinoma In Situ at the Lumpectomy Margin Increase Local Recurrence?
CONCLUSIONS: For completely excised invasive breast cancers associated with NC-LCIS, extent of margin width for NC-LCIS was not associated with a difference in IBTR or LRR. These data suggest that the decision to perform reexcision of margin after lumpectomy should be driven by the invasive cancer, rather than the NC-LCIS margin.PMID:37493892 | DOI:10.1245/s10434-023-13899-1 (Source: Ann Oncol)
Source: Ann Oncol - July 26, 2023 Category: Cancer & Oncology Authors: Anna C Beck Solange Bayard George Plitas Varadan Sevilimedu M Gabriela Kuba Paula Garcia Monica Morrow Audree B Tadros Source Type: research

Is Choosing Wisely Wise for Lobular Carcinoma in Patients Over 70  Years of Age? A National Cancer Database Analysis of Sentinel Node Practice Patterns
CONCLUSION: A trend de-escalation of axillary staging was identified in this study, however the majority of patients meeting the 'Choosing Wisely' criteria are still undergoing SLNBx. No increased risk of nodal positivity was identified among patients with ILC, suggesting that surgeons can continue to choose wisely and limit the use of SLNBx in women over 70 years of age with T1 ILC tumors.PMID:37490163 | DOI:10.1245/s10434-023-13886-6 (Source: Ann Oncol)
Source: Ann Oncol - July 25, 2023 Category: Cancer & Oncology Authors: Nicole H Goldhaber Thomas O'Keefe Jessica Kang Sasha Douglas Sarah L Blair Source Type: research

Absence of Lobular Carcinoma In Situ is a Poor Prognostic Marker in Invasive Lobular Carcinoma
To determine if the outcomes of patients with ILC co-occurring with LCIS are similar to pure ILC and if the presence of LCIS is a prognostic factor for ILC. (Source: European Journal of Cancer)
Source: European Journal of Cancer - July 21, 2023 Category: Cancer & Oncology Authors: Jason A. Mouabbi, Akshara Singareeka Raghavendra, Roland L. Bassett, Matthias Christgen, Lavinia Middleton, Mediget Teshome, Azadeh Nasrazadani, Gabriel Hortobagyi, Amy Hassan, Debasish Tripathy, Rachel M. Layman Tags: Original Research Source Type: research