Machine Learning Approach for the Determination of the Best Cut-Off Points for Ki67 Proliferation Index in Adjuvant and Neo-Adjuvant Therapy Breast Cancer Patients
CONCLUSION: Despite variability in measurement and cut-off points, the Ki-67 proliferation index is still helpful in the clinic. Further investigation is needed to determine the best cut-off points for different patients. The sensitivity and specificity of Ki-67 cutoff point prediction models in this study could further prove its significance as a prognostic factor.PMID:37156698 | DOI:10.1016/j.clbc.2023.03.015 (Source: Clinical Genitourinary Cancer)
Source: Clinical Genitourinary Cancer - May 8, 2023 Category: Cancer & Oncology Authors: Sepehr Khosravi Amirmahdi Khayyamfar Jamileh Karimi Mahdieh Tutuni Alireza Negahi Mohamad Esmaeil Akbari Nahid Nafissi Source Type: research
Machine Learning Approach for the Determination of the Best Cut-Off Points for Ki67 Proliferation Index in Adjuvant and Neo-Adjuvant Therapy Breast Cancer Patients
CONCLUSION: Despite variability in measurement and cut-off points, the Ki-67 proliferation index is still helpful in the clinic. Further investigation is needed to determine the best cut-off points for different patients. The sensitivity and specificity of Ki-67 cutoff point prediction models in this study could further prove its significance as a prognostic factor.PMID:37156698 | DOI:10.1016/j.clbc.2023.03.015 (Source: Clinical Breast Cancer)
Source: Clinical Breast Cancer - May 8, 2023 Category: Cancer & Oncology Authors: Sepehr Khosravi Amirmahdi Khayyamfar Jamileh Karimi Mahdieh Tutuni Alireza Negahi Mohamad Esmaeil Akbari Nahid Nafissi Source Type: research
Machine Learning Approach for the Determination of the Best Cut-Off Points for Ki67 Proliferation Index in Adjuvant and Neo-Adjuvant Therapy Breast Cancer Patients
CONCLUSION: Despite variability in measurement and cut-off points, the Ki-67 proliferation index is still helpful in the clinic. Further investigation is needed to determine the best cut-off points for different patients. The sensitivity and specificity of Ki-67 cutoff point prediction models in this study could further prove its significance as a prognostic factor.PMID:37156698 | DOI:10.1016/j.clbc.2023.03.015 (Source: Clinical Genitourinary Cancer)
Source: Clinical Genitourinary Cancer - May 8, 2023 Category: Cancer & Oncology Authors: Sepehr Khosravi Amirmahdi Khayyamfar Jamileh Karimi Mahdieh Tutuni Alireza Negahi Mohamad Esmaeil Akbari Nahid Nafissi Source Type: research
Pathologic Tumor Size versus Mammography, Sonography, and MRI in Breast Cancer Based on Pathologic Subtypes
DISCUSSION: Mammography and MRI consistently overestimated tumor size with the exception of ILC while US underestimated tumor size on all pathologic subtypes. MRI significantly overestimated tumor size in DCIS by 5.77 mm. Mammography was the most accurate imaging modality for all pathologic subtypes and never had a statistically significant difference from actual tumor size.PMID:37140069 | DOI:10.1177/00031348231174019 (Source: The American Surgeon)
Source: The American Surgeon - May 4, 2023 Category: Surgery Authors: Cory J Nonnemacher Paul Dale Anthony Scott Mary Bonner Source Type: research
Carcinoma with signet ring cell differentiation associated with invasive breast cancer: A case report
Oncol Lett. 2023 Apr 6;25(5):212. doi: 10.3892/ol.2023.13798. eCollection 2023 May.ABSTRACTCarcinoma with signet ring cell differentiation is uncommon in patients with invasive breast cancer. Clinical evidence has suggested that the prognosis of this tumor is usually poor if the stage is advanced. The case of a 40-year-old female patient with primary cancer in the right breast accompanied by bilateral neck, axillary, right subclavian and mediastinal lymph node metastases, and left breast metastasis is presented in the current study. The patient developed superior vena cava syndrome and was restricted in lifting the upper r...
Source: Oncology Letters - May 1, 2023 Category: Cancer & Oncology Authors: Wei Yang Shun Ding Litao Wang Fupeng Ren Yunying Lai Hongfang Wang Huan Wang Guodai Hong Wenbin Gao Source Type: research
Performance of [18F]FDG-PET/CT Imaging in First Recurrence of Invasive Lobular Carcinoma
CONCLUSIONS: FDG-PET/CT is an effective and reliable tool for the detection of invasive lobular carcinoma recurrence, although certain recurrence sites specific to this histological type can impair its diagnostic performance.PMID:37109252 | DOI:10.3390/jcm12082916 (Source: Clinical Lung Cancer)
Source: Clinical Lung Cancer - April 28, 2023 Category: Cancer & Oncology Authors: David Bonnin Sylvain Ladoire Nathalie Briot Aur élie Bertaut Cl ément Drouet Alexandre Cochet Jean-Louis Alberini Source Type: research
Performance of [18F]FDG-PET/CT Imaging in First Recurrence of Invasive Lobular Carcinoma
CONCLUSIONS: FDG-PET/CT is an effective and reliable tool for the detection of invasive lobular carcinoma recurrence, although certain recurrence sites specific to this histological type can impair its diagnostic performance.PMID:37109252 | DOI:10.3390/jcm12082916 (Source: Clinical Breast Cancer)
Source: Clinical Breast Cancer - April 28, 2023 Category: Cancer & Oncology Authors: David Bonnin Sylvain Ladoire Nathalie Briot Aur élie Bertaut Cl ément Drouet Alexandre Cochet Jean-Louis Alberini Source Type: research
Performance of [18F]FDG-PET/CT Imaging in First Recurrence of Invasive Lobular Carcinoma
CONCLUSIONS: FDG-PET/CT is an effective and reliable tool for the detection of invasive lobular carcinoma recurrence, although certain recurrence sites specific to this histological type can impair its diagnostic performance.PMID:37109252 | DOI:10.3390/jcm12082916 (Source: Clinical Genitourinary Cancer)
Source: Clinical Genitourinary Cancer - April 28, 2023 Category: Cancer & Oncology Authors: David Bonnin Sylvain Ladoire Nathalie Briot Aur élie Bertaut Cl ément Drouet Alexandre Cochet Jean-Louis Alberini Source Type: research
Performance of [18F]FDG-PET/CT Imaging in First Recurrence of Invasive Lobular Carcinoma
CONCLUSIONS: FDG-PET/CT is an effective and reliable tool for the detection of invasive lobular carcinoma recurrence, although certain recurrence sites specific to this histological type can impair its diagnostic performance.PMID:37109252 | PMC:PMC10144846 | DOI:10.3390/jcm12082916 (Source: Clinical Lung Cancer)
Source: Clinical Lung Cancer - April 28, 2023 Category: Cancer & Oncology Authors: David Bonnin Sylvain Ladoire Nathalie Briot Aur élie Bertaut Cl ément Drouet Alexandre Cochet Jean-Louis Alberini Source Type: research
Altered cytokeratin 5 expression in breast lobular myoepithelial cells
CONCLUSIONS: These results suggest that CK5 expression in lobular MECs may be altered by contact with cancerous luminal cells rather than benign hyperplastic luminal cells or pressure from dilated glands.PMID:37116947 | DOI:10.1136/jcp-2023-208835 (Source: Clinical Breast Cancer)
Source: Clinical Breast Cancer - April 28, 2023 Category: Cancer & Oncology Authors: Anqi Li Miao Ruan Xiaochun Fei Haimin Xu Shijie Deng Rui Bi Wentao Yang Lei Dong Source Type: research
