Machine Learning Approach for the Determination of the Best Cut-Off Points for Ki67 Proliferation Index in Adjuvant and Neo-Adjuvant Therapy Breast Cancer Patients

CONCLUSION: Despite variability in measurement and cut-off points, the Ki-67 proliferation index is still helpful in the clinic. Further investigation is needed to determine the best cut-off points for different patients. The sensitivity and specificity of Ki-67 cutoff point prediction models in this study could further prove its significance as a prognostic factor.PMID:37156698 | DOI:10.1016/j.clbc.2023.03.015

Source: Clinical Genitourinary Cancer - May 8, 2023 Category: Cancer & Oncology Authors: Sepehr Khosravi Amirmahdi Khayyamfar Jamileh Karimi Mahdieh Tutuni Alireza Negahi Mohamad Esmaeil Akbari Nahid Nafissi Source Type: research