The impact of histologic subtype on primary site surgery in the management of metastatic lobular versus ductal breast cancer: a population based study from the National Cancer Database (NCDB)
CONCLUSION: Lobular histology is associated with less primary site surgery, higher positive margin rates, less radiotherapy and chemotherapy, and shorter OS compared to those with HR-positive HER2-negative IDC. These findings support the need for ILC-specific data and treatment approaches in the setting of metastatic disease.PMID:37833450 | DOI:10.1007/s10549-023-07125-5 (Source: Cancer Control)
Source: Cancer Control - October 13, 2023 Category: Cancer & Oncology Authors: Harriet T Rothschild Elle N Clelland Mary Kathryn Abel A Jo Chien Amy M Shui Laura Esserman Seema A Khan Rita A Mukhtar Source Type: research
FGFR2 genetic variants in women with breast cancer
Mol Med Rep. 2023 Dec;28(6):226. doi: 10.3892/mmr.2023.13113. Epub 2023 Oct 13.ABSTRACTBlack African populations are more genetically diverse than others, but genetic variants have been studied primarily in European populations. The present study examined the association of four single nucleotide polymorphisms (SNPs) of the fibroblast growth factor receptor 2, associated with breast cancer in non‑African populations, with breast cancer in Black, southern African women. Genomic DNA was extracted from whole blood samples of 1,001 patients with breast cancer and 1,006 controls (without breast cancer), and the rs2981582, rs3...
Source: Molecular Medicine - October 13, 2023 Category: Molecular Biology Authors: Th érèse Dix-Peek Caroline Dickens Tanya N Augustine Boitumelo P Phakathi Eunice J Van Den Berg Maureen Joffe Oluwatosin A Ayeni Herbert Cubasch Sarah Nietz Christopher G Mathew Mahtaab Hayat Alfred I Neugut Judith S Jacobson Paul Ruff Raquel A B Duarte Source Type: research
FGFR2 genetic variants in women with breast cancer
Mol Med Rep. 2023 Dec;28(6):226. doi: 10.3892/mmr.2023.13113. Epub 2023 Oct 13.ABSTRACTBlack African populations are more genetically diverse than others, but genetic variants have been studied primarily in European populations. The present study examined the association of four single nucleotide polymorphisms (SNPs) of the fibroblast growth factor receptor 2, associated with breast cancer in non‑African populations, with breast cancer in Black, southern African women. Genomic DNA was extracted from whole blood samples of 1,001 patients with breast cancer and 1,006 controls (without breast cancer), and the rs2981582, rs3...
Source: Molecular Medicine Reports - October 13, 2023 Category: Molecular Biology Authors: Th érèse Dix-Peek Caroline Dickens Tanya N Augustine Boitumelo P Phakathi Eunice J Van Den Berg Maureen Joffe Oluwatosin A Ayeni Herbert Cubasch Sarah Nietz Christopher G Mathew Mahtaab Hayat Alfred I Neugut Judith S Jacobson Paul Ruff Raquel A B Duarte Source Type: research
Digital mammography and digital breast tomosynthesis for detecting invasive lobular and ductal carcinoma
ConclusionDBT was associated with higher CDR for ILC, IDC, and IMC for women with dense breasts. Early detection of ILC with DBT may improve outcomes for this distinct clinical entity. (Source: Breast Cancer Research and Treatment)
Source: Breast Cancer Research and Treatment - October 11, 2023 Category: Cancer & Oncology Source Type: research
Clinical and Imaging Features of MRI Screen-Detected Breast Cancer
CONCLUSION: MRI screen-detected breast cancers were most often invasive cancers. Cancers detected by MRI screening had an excellent prognosis in our study population. Invasive cancers most commonly presented as a mass.PMID:37821332 | DOI:10.1016/j.clbc.2023.09.012 (Source: Clinical Breast Cancer)
Source: Clinical Breast Cancer - October 11, 2023 Category: Cancer & Oncology Authors: Naveen Ghuman Emily B Ambinder Eniola T Oluyemi Elizabeth Sutton Kelly S Myers Source Type: research
Clinical and Imaging Features of MRI Screen-Detected Breast Cancer
CONCLUSION: MRI screen-detected breast cancers were most often invasive cancers. Cancers detected by MRI screening had an excellent prognosis in our study population. Invasive cancers most commonly presented as a mass.PMID:37821332 | DOI:10.1016/j.clbc.2023.09.012 (Source: Clinical Genitourinary Cancer)
Source: Clinical Genitourinary Cancer - October 11, 2023 Category: Cancer & Oncology Authors: Naveen Ghuman Emily B Ambinder Eniola T Oluyemi Elizabeth Sutton Kelly S Myers Source Type: research
The management of locally advanced, ulcerated breast cancer in a menopausal woman: a case report
CONCLUSION: This case report emphasizes the necessity for a comprehensive and patient-centered approach to managing complex cases of breast cancer. The findings support the development of personalized therapeutic strategies aimed at improving patient outcomes and quality of life. The successful treatment of the locally advanced, ulcerated lobular carcinoma of the breast in this postmenopausal patient further highlights the importance of considering individual factors and tailoring treatment plans accordingly.PMID:37811082 | PMC:PMC10553047 | DOI:10.1097/MS9.0000000000001187 (Source: Annals of Medicine)
Source: Annals of Medicine - October 9, 2023 Category: Internal Medicine Authors: Paolo Izzo Luciano Izzo Andrea Polistena Simone Sibio Massimo Codacci-Pisanelli Daniele Crocetti Raimondo Gabriele Claudia De Intinis Sara Izzo Source Type: research
Traumatic sigmoid colon rupture due to breast cancer metastasis: a case report
Clin J Gastroenterol. 2023 Sep 21. doi: 10.1007/s12328-023-01859-x. Online ahead of print.ABSTRACTThe metastasis of breast cancer to the gastrointestinal tract is rare. Herein, we presented the case of an 85-year-old woman who had a history of invasive lobular carcinoma and experienced complete colon rupture due to relatively low-energy trauma. The patient underwent bilateral total mastectomy and axillary dissection following preoperative chemotherapy 6 years ago. She had a local recurrence 2 years after the surgery and underwent chemotherapy. Subsequently, the cancer metastasized to the thoracolumbar area and retroperiton...
Source: Clinical Breast Cancer - September 21, 2023 Category: Cancer & Oncology Authors: Tomonori Yoshida Munenori Ide Kazuhisa Katayama Mitsuhiro Yanai Ryo Kurosaki Hisashi Shimizu Kazuhisa Arakawa Tatsuya Miyazaki Hiroshi Saeki Ken Shirabe Source Type: research
Traumatic sigmoid colon rupture due to breast cancer metastasis: a case report
Clin J Gastroenterol. 2023 Sep 21. doi: 10.1007/s12328-023-01859-x. Online ahead of print.ABSTRACTThe metastasis of breast cancer to the gastrointestinal tract is rare. Herein, we presented the case of an 85-year-old woman who had a history of invasive lobular carcinoma and experienced complete colon rupture due to relatively low-energy trauma. The patient underwent bilateral total mastectomy and axillary dissection following preoperative chemotherapy 6 years ago. She had a local recurrence 2 years after the surgery and underwent chemotherapy. Subsequently, the cancer metastasized to the thoracolumbar area and retroperiton...
Source: Clinical Genitourinary Cancer - September 21, 2023 Category: Cancer & Oncology Authors: Tomonori Yoshida Munenori Ide Kazuhisa Katayama Mitsuhiro Yanai Ryo Kurosaki Hisashi Shimizu Kazuhisa Arakawa Tatsuya Miyazaki Hiroshi Saeki Ken Shirabe Source Type: research
Traumatic sigmoid colon rupture due to breast cancer metastasis: a case report
Clin J Gastroenterol. 2023 Sep 21. doi: 10.1007/s12328-023-01859-x. Online ahead of print.ABSTRACTThe metastasis of breast cancer to the gastrointestinal tract is rare. Herein, we presented the case of an 85-year-old woman who had a history of invasive lobular carcinoma and experienced complete colon rupture due to relatively low-energy trauma. The patient underwent bilateral total mastectomy and axillary dissection following preoperative chemotherapy 6 years ago. She had a local recurrence 2 years after the surgery and underwent chemotherapy. Subsequently, the cancer metastasized to the thoracolumbar area and retroperiton...
Source: Clinical Breast Cancer - September 21, 2023 Category: Cancer & Oncology Authors: Tomonori Yoshida Munenori Ide Kazuhisa Katayama Mitsuhiro Yanai Ryo Kurosaki Hisashi Shimizu Kazuhisa Arakawa Tatsuya Miyazaki Hiroshi Saeki Ken Shirabe Source Type: research
