Renal Cell Carcinoma as the Cause of Lower Inflow Congestion
Dtsch Arztebl Int. 2024 Mar 22;121(6):195. doi: 10.3238/arztebl.m2023.0186.NO ABSTRACTPMID:38666673 | DOI:10.3238/arztebl.m2023.0186 (Source: Deutsches Arzteblatt International)
Source: Deutsches Arzteblatt International - April 26, 2024 Category: General Medicine Authors: Paul Witte Tobias Gassenmaier Michael Christ Source Type: research

In Silico and In Vitro Study of Isoquercitrin against Kidney Cancer and Inflammation by Triggering Potential Gene Targets
Curr Issues Mol Biol. 2024 Apr 12;46(4):3328-3341. doi: 10.3390/cimb46040208.ABSTRACTKidney cancer has emerged as a major medical problem in recent times. Multiple compounds are used to treat kidney cancer by triggering cancer-causing gene targets. For instance, isoquercitrin (quercetin-3-O-β-d-glucopyranoside) is frequently present in fruits, vegetables, medicinal herbs, and foods and drinks made from plants. Our previous study predicted using protein-protein interaction (PPI) and molecular docking analysis that the isoquercitrin compound can control kidney cancer and inflammation by triggering potential gene targets of ...
Source: Current Issues in Molecular Biology - April 26, 2024 Category: Molecular Biology Authors: Safia Iqbal Md Rezaul Karim Shahnawaz Mohammad Jong Chan Ahn Anjali Kariyarath Valappil Ramya Mathiyalagan Deok-Chun Yang Dae-Hyo Jung Hyocheol Bae Dong Uk Yang Source Type: research

Radiogenomics and Texture Analysis to Detect von Hippel-Lindau (VHL) Mutation in Clear Cell Renal Cell Carcinoma
Curr Issues Mol Biol. 2024 Apr 8;46(4):3236-3250. doi: 10.3390/cimb46040203.ABSTRACTRadiogenomics, a burgeoning field in biomedical research, explores the correlation between imaging features and genomic data, aiming to link macroscopic manifestations with molecular characteristics. In this review, we examine existing radiogenomics literature in clear cell renal cell carcinoma (ccRCC), the predominant renal cancer, and von Hippel-Lindau (VHL) gene mutation, the most frequent genetic mutation in ccRCC. A thorough examination of the literature was conducted through searches on the PubMed, Medline, Cochrane Library, Google Sc...
Source: Current Issues in Molecular Biology - April 26, 2024 Category: Molecular Biology Authors: Federico Greco Valerio D'Andrea Bruno Beomonte Zobel Carlo Augusto Mallio Source Type: research

In Silico and In Vitro Study of Isoquercitrin against Kidney Cancer and Inflammation by Triggering Potential Gene Targets
Curr Issues Mol Biol. 2024 Apr 12;46(4):3328-3341. doi: 10.3390/cimb46040208.ABSTRACTKidney cancer has emerged as a major medical problem in recent times. Multiple compounds are used to treat kidney cancer by triggering cancer-causing gene targets. For instance, isoquercitrin (quercetin-3-O-β-d-glucopyranoside) is frequently present in fruits, vegetables, medicinal herbs, and foods and drinks made from plants. Our previous study predicted using protein-protein interaction (PPI) and molecular docking analysis that the isoquercitrin compound can control kidney cancer and inflammation by triggering potential gene targets of ...
Source: Mol Biol Cell - April 26, 2024 Category: Molecular Biology Authors: Safia Iqbal Md Rezaul Karim Shahnawaz Mohammad Jong Chan Ahn Anjali Kariyarath Valappil Ramya Mathiyalagan Deok-Chun Yang Dae-Hyo Jung Hyocheol Bae Dong Uk Yang Source Type: research

Radiogenomics and Texture Analysis to Detect von Hippel-Lindau (VHL) Mutation in Clear Cell Renal Cell Carcinoma
Curr Issues Mol Biol. 2024 Apr 8;46(4):3236-3250. doi: 10.3390/cimb46040203.ABSTRACTRadiogenomics, a burgeoning field in biomedical research, explores the correlation between imaging features and genomic data, aiming to link macroscopic manifestations with molecular characteristics. In this review, we examine existing radiogenomics literature in clear cell renal cell carcinoma (ccRCC), the predominant renal cancer, and von Hippel-Lindau (VHL) gene mutation, the most frequent genetic mutation in ccRCC. A thorough examination of the literature was conducted through searches on the PubMed, Medline, Cochrane Library, Google Sc...
Source: Mol Biol Cell - April 26, 2024 Category: Molecular Biology Authors: Federico Greco Valerio D'Andrea Bruno Beomonte Zobel Carlo Augusto Mallio Source Type: research

[Corrigendum] MicroRNA ‑222‑3p promotes tumor cell migration and invasion and inhibits apoptosis, and is correlated with an unfavorable prognosis of patients with renal cell carcinoma
Int J Mol Med. 2024 Jun;53(6):53. doi: 10.3892/ijmm.2024.5377. Epub 2024 Apr 26.ABSTRACTFollowing the publication of the above article, an interested reader drew to the attention of the Editorial Office that, in Fig. 3A on p. 530, two pairs of data panels were overlapping, such that certain of the panels appeared to have been derived from the same original sources where the results from differently performed experiments were intended to have been portrayed. The authors have examined their original data, and realize that errors associated with data handling/labelling during the preparation of the representative images in Fi...
Source: International Journal of Molecular Medicine - April 26, 2024 Category: Molecular Biology Authors: Liwen Zhao Jing Quan Zuwei Li Xiang Pan Jingyao Wang Jinling Xu Weijie Xu Xin Guan Hang Li Shangqi Yang Yaoting Gui Yun Chen Yongqing Lai Source Type: research

[Retracted] lncRNA ROR promotes the progression of renal cell carcinoma through the miR ‑206/VEGF axis
Mol Med Rep. 2024 Jun;29(6):105. doi: 10.3892/mmr.2024.13229. Epub 2024 Apr 26.ABSTRACTFollowing the publication of this paper, it was drawn to the Editor's attention by a concerned reader that certain of the Transwell cell invasion and migration assay data shown in Fig. 2D and F on p. 3786 were strikingly similar to data appearing in different form in other articles written by different authors at different research institutes, which had already been published. Owing to the fact that the contentious data in the above article had already been published prior to its submission to Molecular Medicine Reports, the Editor has d...
Source: Molecular Medicine - April 26, 2024 Category: Molecular Biology Authors: Jianguo Shi Datian Zhang Zhenhai Zhong Wen Zhang Source Type: research

[Corrigendum] MicroRNA ‑222‑3p promotes tumor cell migration and invasion and inhibits apoptosis, and is correlated with an unfavorable prognosis of patients with renal cell carcinoma
Int J Mol Med. 2024 Jun;53(6):53. doi: 10.3892/ijmm.2024.5377. Epub 2024 Apr 26.ABSTRACTFollowing the publication of the above article, an interested reader drew to the attention of the Editorial Office that, in Fig. 3A on p. 530, two pairs of data panels were overlapping, such that certain of the panels appeared to have been derived from the same original sources where the results from differently performed experiments were intended to have been portrayed. The authors have examined their original data, and realize that errors associated with data handling/labelling during the preparation of the representative images in Fi...
Source: Molecular Medicine - April 26, 2024 Category: Molecular Biology Authors: Liwen Zhao Jing Quan Zuwei Li Xiang Pan Jingyao Wang Jinling Xu Weijie Xu Xin Guan Hang Li Shangqi Yang Yaoting Gui Yun Chen Yongqing Lai Source Type: research

[Retracted] lncRNA ROR promotes the progression of renal cell carcinoma through the miR ‑206/VEGF axis
Mol Med Rep. 2024 Jun;29(6):105. doi: 10.3892/mmr.2024.13229. Epub 2024 Apr 26.ABSTRACTFollowing the publication of this paper, it was drawn to the Editor's attention by a concerned reader that certain of the Transwell cell invasion and migration assay data shown in Fig. 2D and F on p. 3786 were strikingly similar to data appearing in different form in other articles written by different authors at different research institutes, which had already been published. Owing to the fact that the contentious data in the above article had already been published prior to its submission to Molecular Medicine Reports, the Editor has d...
Source: Molecular Medicine Reports - April 26, 2024 Category: Molecular Biology Authors: Jianguo Shi Datian Zhang Zhenhai Zhong Wen Zhang Source Type: research

Antibody-Drug Conjugates in the Treatment of Genitourinary Cancers: An Updated Review of Data
In this study, we have thoroughly completed a narrative review of the current literature and summarized preclinical studies and clinical trials that evaluated the utility, activity, and toxicity of ADCs in GU cancers, the prospects of ADC development, and the ongoing clinical trials. Prospective clinical trials, retrospective studies, case reports, and scoping reviews were included.PMID:38668075 | PMC:PMC11049516 | DOI:10.3390/curroncol31040172 (Source: Current Oncology)
Source: Current Oncology - April 26, 2024 Category: Cancer & Oncology Authors: Prathana Nathan Adnan Rajeh Meh Noor Gabriel Boldt Ricardo Fernandes Source Type: research

Soluble Immune Checkpoint Molecules as Predictors of Efficacy in Immuno-Oncology Combination Therapy in Advanced Renal Cell Carcinoma
In conclusion, sPD-L2 and sLAG-3 expression may serve as a potential biomarker for predicting IO combination therapy efficacy.PMID:38668032 | PMC:PMC11049572 | DOI:10.3390/curroncol31040129 (Source: Current Oncology)
Source: Current Oncology - April 26, 2024 Category: Cancer & Oncology Authors: Kosuke Ueda Keiichiro Uemura Naoki Ito Yuya Sakai Satoshi Ohnishi Hiroki Suekane Hirofumi Kurose Tasuku Hiroshige Katsuaki Chikui Kiyoaki Nishihara Makoto Nakiri Shigetaka Suekane Sachiko Ogasawara Hirohisa Yano Tsukasa Igawa Source Type: research

Renal Cell Carcinoma as the Cause of Lower Inflow Congestion
Dtsch Arztebl Int. 2024 Mar 22;121(6):195. doi: 10.3238/arztebl.m2023.0186.NO ABSTRACTPMID:38666673 | DOI:10.3238/arztebl.m2023.0186 (Source: Deutsches Arzteblatt International)
Source: Deutsches Arzteblatt International - April 26, 2024 Category: General Medicine Authors: Paul Witte Tobias Gassenmaier Michael Christ Source Type: research

In Silico and In Vitro Study of Isoquercitrin against Kidney Cancer and Inflammation by Triggering Potential Gene Targets
Curr Issues Mol Biol. 2024 Apr 12;46(4):3328-3341. doi: 10.3390/cimb46040208.ABSTRACTKidney cancer has emerged as a major medical problem in recent times. Multiple compounds are used to treat kidney cancer by triggering cancer-causing gene targets. For instance, isoquercitrin (quercetin-3-O-β-d-glucopyranoside) is frequently present in fruits, vegetables, medicinal herbs, and foods and drinks made from plants. Our previous study predicted using protein-protein interaction (PPI) and molecular docking analysis that the isoquercitrin compound can control kidney cancer and inflammation by triggering potential gene targets of ...
Source: Current Issues in Molecular Biology - April 26, 2024 Category: Molecular Biology Authors: Safia Iqbal Md Rezaul Karim Shahnawaz Mohammad Jong Chan Ahn Anjali Kariyarath Valappil Ramya Mathiyalagan Deok-Chun Yang Dae-Hyo Jung Hyocheol Bae Dong Uk Yang Source Type: research

Radiogenomics and Texture Analysis to Detect von Hippel-Lindau (VHL) Mutation in Clear Cell Renal Cell Carcinoma
Curr Issues Mol Biol. 2024 Apr 8;46(4):3236-3250. doi: 10.3390/cimb46040203.ABSTRACTRadiogenomics, a burgeoning field in biomedical research, explores the correlation between imaging features and genomic data, aiming to link macroscopic manifestations with molecular characteristics. In this review, we examine existing radiogenomics literature in clear cell renal cell carcinoma (ccRCC), the predominant renal cancer, and von Hippel-Lindau (VHL) gene mutation, the most frequent genetic mutation in ccRCC. A thorough examination of the literature was conducted through searches on the PubMed, Medline, Cochrane Library, Google Sc...
Source: Current Issues in Molecular Biology - April 26, 2024 Category: Molecular Biology Authors: Federico Greco Valerio D'Andrea Bruno Beomonte Zobel Carlo Augusto Mallio Source Type: research

[Corrigendum] MicroRNA ‑222‑3p promotes tumor cell migration and invasion and inhibits apoptosis, and is correlated with an unfavorable prognosis of patients with renal cell carcinoma
Int J Mol Med. 2024 Jun;53(6):53. doi: 10.3892/ijmm.2024.5377. Epub 2024 Apr 26.ABSTRACTFollowing the publication of the above article, an interested reader drew to the attention of the Editorial Office that, in Fig. 3A on p. 530, two pairs of data panels were overlapping, such that certain of the panels appeared to have been derived from the same original sources where the results from differently performed experiments were intended to have been portrayed. The authors have examined their original data, and realize that errors associated with data handling/labelling during the preparation of the representative images in Fi...
Source: International Journal of Molecular Medicine - April 26, 2024 Category: Molecular Biology Authors: Liwen Zhao Jing Quan Zuwei Li Xiang Pan Jingyao Wang Jinling Xu Weijie Xu Xin Guan Hang Li Shangqi Yang Yaoting Gui Yun Chen Yongqing Lai Source Type: research