Zika Virus Infection Associated with Autism Spectrum Disorder: A Case Report
Conclusion: Accordingly, this report firstly associates ZIKV exposure to ASD.Neuroimmunomodulation (Source: Neuroimmunomodulation)
Source: Neuroimmunomodulation - June 3, 2021 Category: Allergy & Immunology Source Type: research
Effects of the Health Belief Model-Based Intervention on Anxiety, Depression, and Quality of Life in Chronic Obstructive Pulmonary Disease
Conclusion: The HBM-based intervention alleviates anxiety and depression, enhances quality of life, and inhibits inflammation in COPD patients entering PR.Neuroimmunomodulation (Source: Neuroimmunomodulation)
Source: Neuroimmunomodulation - June 1, 2021 Category: Allergy & Immunology Source Type: research
Retraction Statement
Neuroimmunomodulation (Source: Neuroimmunomodulation)
Source: Neuroimmunomodulation - May 31, 2021 Category: Allergy & Immunology Source Type: research
Caspase-11 Noncanonical Inflammasome: A Novel Key Player in Murine Models of Neuroinflammation and Multiple Sclerosis
Inflammasomes are intracellular protein complexes consisting of the pattern recognition receptors and inflammatory molecules in the inflamed cells. In response to various ligands, inflammasomes play a pivotal role to execute the inflammatory responses by inducing the pyroptosis and the secretion of pro-inflammatory cytokines, interleukin (IL)-1 β, and IL-18. Unlike canonical inflammasomes, including NOD-like receptor family inflammasomes, such as NLRP1, NLRP3, NLRC4, and absence in melanoma 2 inflammasomes, noncanonical inflammasomes, such as mouse caspase-11 and human caspase-4/5 were recently discovered, and their roles...
Source: Neuroimmunomodulation - May 27, 2021 Category: Allergy & Immunology Source Type: research
Depression Is Associated with Downregulation of IPS-1 in Chronic HBV-Infected Patients in a Sex-Dependent Manner
Conclusion: So, it was hypothesized that depression may be associated with alteration in the expression of IPS-1 in a sex-dependent manner. In other words, it appears that the male CHB patients are at risk of depression-related alteration in immune-related gene expression.Neuroimmunomodulation (Source: Neuroimmunomodulation)
Source: Neuroimmunomodulation - May 6, 2021 Category: Allergy & Immunology Source Type: research
Activation of Insulin-Like Growth Factor-2 Ameliorates Retinal Cell Damage and Exerts Protection in in vitro Model of Diabetic Retinopathy
Conclusion: The finding of the investigation, therefore, shows that the use of IGF2 activators may prevent the progression of ocular dysfunction in the control of diabetes-related complications.Neuroimmunomodulation (Source: Neuroimmunomodulation)
Source: Neuroimmunomodulation - May 5, 2021 Category: Allergy & Immunology Source Type: research
Neurovascular Interactions in Malaria
Malaria is caused byPlasmodium infection and remains a serious public health problem worldwide, despite control efforts. Malaria can progress to severe forms, affecting multiple organs, including the brain causing cerebral malaria (CM). CM is the most severe neurological complication of malaria, and cognitive and behavior deficits are commonly reported in surviving patients. The number of deaths from malaria has been reducing in recent years, and as a consequence, neurological sequelae have been more evident. Neurological damage in malaria might be related to the neuroinflammation, characterized by glia cell activation, ne...
Source: Neuroimmunomodulation - May 5, 2021 Category: Allergy & Immunology Source Type: research
Neuroinflammation in Mood Disorders: Role of Regulatory Immune Cells
In conclusion, maladaptive immunoregulatory mechanisms seem to be involved with both onset and progression of mood disorders. A deeper understanding of these mechanisms may lead to the development of new therapeutic strategies.Neuroimmunomodulation (Source: Neuroimmunomodulation)
Source: Neuroimmunomodulation - May 5, 2021 Category: Allergy & Immunology Source Type: research
Clinical Characteristics of Chinese Male Patients with Aquaporin-4 Antibody-Positive Late-Onset Neuromyelitis Optica Spectrum Disorder
Conclusion: Less common TM at onset, less disease severity, and shorter time from onset to diagnosis probably occur in male LONMOSD patients.Neuroimmunomodulation (Source: Neuroimmunomodulation)
Source: Neuroimmunomodulation - May 4, 2021 Category: Allergy & Immunology Source Type: research
SARS-CoV-2 Infection in Pregnant Women: Neuroimmune-Endocrine Changes at the Maternal-Fetal Interface
Coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome-related coronavirus 2 (SARS-CoV-2) has devastating effects on the population worldwide. Given this scenario, the extent of the impact of the disease on more vulnerable individuals, such as pregnant women, is of great concern. Although pregnancy may be a risk factor in respiratory virus infections, there are no considerable differences regarding COVID-19 severity observed between pregnant and nonpregnant women. In these circumstances, an emergent concern is the possibility of neurodevelopmental and neuropsychiatric harm for the offspring of infe...
Source: Neuroimmunomodulation - April 28, 2021 Category: Allergy & Immunology Source Type: research
Curcumin Reduces Neuroinflammation and Improves the Impairments of Anesthetics on Learning and Memory by Regulating the Expression of miR-181a-5p
Conclusion: Cur has a protective effect on ISO-induced cognitive dysfunction, which may be achieved by regulating the expression of miR-181a-5p.Neuroimmunomodulation (Source: Neuroimmunomodulation)
Source: Neuroimmunomodulation - April 13, 2021 Category: Allergy & Immunology Source Type: research
Stress-Related Brain Neuroinflammation Impact in Depression: Role of the Corticotropin-Releasing Hormone System and P2X7 Receptor
Depression and other psychiatric stress-related disorders are leading causes of disability worldwide. Up to date, treatments of mood disorders have limited success, most likely due to the multifactorial etiology of these conditions. Alterations in inflammatory processes have been identified as possible pathophysiological mechanisms in psychiatric conditions. Here, we review the main features of 2 systems involved in the control of these inflammatory pathways: the CRH system as a key regulator of the stress response and the ATP-gated ion-channel P2X7 receptor (P2X7R) involved in the control of immune functions. The pathophy...
Source: Neuroimmunomodulation - April 12, 2021 Category: Allergy & Immunology Source Type: research
Contents, Vol. 27, 2020
Neuroimmunomodulation 2020;27:I –IV (Source: Neuroimmunomodulation)
Source: Neuroimmunomodulation - March 31, 2021 Category: Allergy & Immunology Source Type: research
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Neuroimmunomodulation 2020;27:I –IV (Source: Neuroimmunomodulation)
Source: Neuroimmunomodulation - March 31, 2021 Category: Allergy & Immunology Source Type: research
Acknowledgement to Reviewers
Neuroimmunomodulation 2020;27:203 (Source: Neuroimmunomodulation)
Source: Neuroimmunomodulation - March 31, 2021 Category: Allergy & Immunology Source Type: research
